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    South Carolina Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Myrtle Beach, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Conway, SC
    3,004 properties
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    Retail Space with Highway Access
    Retail Space with Highway Access

    1040 Oak Forest Ln., Myrtle Beach, SC 29577

    $5,446/Mo
    1,556 sqft

    HC-zoned retail space near major shopping destinations and regional road connections.

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    First-Floor Professional Office Suite
    First-Floor Professional Office Suite

    3876 Renee Dr., Myrtle Beach, SC 29579

    $3,920/Mo
    9–15 people  2,352 sqft  0.56 acres

    Eight private offices, two conference rooms, and a reception area create a defined workspace layout.

    13 parking spaces
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    Medical Office Space in Office Park
    Medical Office Space in Office Park

    710 21st Ave. N, Myrtle Beach, SC 29577

    $1,040/Mo
    567 sqft  0.16 acres

    A 567-square-foot offering is part of a two-building professional office campus in Myrtle Beach.

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    Fully Serviced Business Solutions at Fountian Park. Contact us today to book a tour!
    Fully Serviced Business Solutions at Fountian Park. Contact us today to book a tour!

    331 E Main St, Unit 200, Rock Hill, SC 29730

    Coworking
    $129-$29,257/Mo per office
    1–15 people  16 spaces  11–2,254 sqft

    Flexible workspace in Fountian Park. Book a tour & get info

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    Multi-Suite Office Property
    Multi-Suite Office Property

    1013 Surf Pine Dr., Surfside Beach, SC 29575

    $4,500/Mo
    13–22 people  3,419 sqft  0.6 acres

    Flexible office configuration with private rooms, meeting areas, kitchen facilities, storage, and a secured outdoor yard.

    20 parking spaces
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    Open-Plan Retail Space
    Open-Plan Retail Space

    741 Bultman Drive, Sumter, SC 29150

    $650/Mo
    513 sqft

    The lease includes water, sewer, and dumpster service, with public water and sewer connections.

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    Office Suite with Private Offices
    Office Suite with Private Offices

    2001 Ocean Blvd. S, Myrtle Beach, SC 29577

    $2,500/Mo
    8–14 people  2,200 sqft

    A former professional-office layout includes reception, private rooms, a work area, and two restrooms.

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    Workspace Solutions at Millport at Butler. Contact us today to book a tour!
    Workspace Solutions at Millport at Butler. Contact us today to book a tour!

    128 Millport Cir, Unit 200, Greenville, SC 29607

    Coworking
    $129-$21,652/Mo per office
    1–14 people  16 spaces  11–2,174 sqft

    Flexible workspace in Millport at Butler. Book a tour & get info

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    Retail Space at Hammock Shops Village
    Retail Space at Hammock Shops Village

    10880 Ocean Highway, Pawleys Island, SC 29585

    $4,336/Mo
    2,365 sqft

    GC-zoned space includes dressing rooms, a private restroom and exterior storage.

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    Historic Retail Space with Loft Areas
    Historic Retail Space with Loft Areas

    110 E Main Street, Union, SC 29379

    $2,300/Mo
    4,200 sqft

    Character-rich commercial space with flexible areas, exposed brick, arched windows, and built-in shelving.

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    Medical Office Space with Drop-Off Area
    Medical Office Space with Drop-Off Area

    230 Giles Dr, Boiling Springs, SC 29316

    $6,730/Mo
    6,730 sqft  1.25 acres

    Private offices, shared work areas, and a dedicated vehicle drop-off area provide a flexible existing layout.

    25 parking spaces
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    Corner Retail Space
    Corner Retail Space

    1089 Alice Drive, Sumter, SC 29150

    $1,603/Mo
    Multi-tenant  1,267 sqft
    Bakers Sweets, Ward's BBQ co-tenants  Corner location

    Open-plan commercial space includes one office and a half bath for flexible retail or office use.

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    Dental Medical Office Suite
    Dental Medical Office Suite

    417 W Cheves Street, Florence, SC 29501

    $3,000/Mo
    1,850 sqft  Built 1979

    The layout includes operatories, laboratory space, reception areas, and a private office.

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    Office Units with Separate Entrances
    Office Units with Separate Entrances

    8311 Two Notch Road, Columbia, SC 29223

    $7,500/Mo
    23–39 people  5,969 sqft  Built 1985
    Highway access

    Interior conference, break, and storage areas support day-to-day business operations.

    Conference room  Kitchen/break area  Storage  Private entrances
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    Medical Office Suite in Professional Park
    Medical Office Suite in Professional Park

    710 21st Ave. N, Myrtle Beach, SC 29577

    $1,166/Mo
    560 sqft  0.16 acres

    The space is part of a multi-building office park with medical and professional units.

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    Renovated Medical Office Suite
    Renovated Medical Office Suite

    4310 Highway 17 Business, Murrells Inlet, SC 29576

    $8,000/Mo
    3,557 sqft  3 acres

    Recently renovated Class A space with shared patient amenities, dedicated elevators, and services included in the lease package.

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    Retail Space with Dual Signage
    Retail Space with Dual Signage

    2818 Devine St, Columbia, SC 29205

    $3,334/Mo
    3,334 sqft

    Available in February 2027 with customer parking and signage at both entrances.

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    Oceanfront Retail Space
    Oceanfront Retail Space

    2310 N Ocean Blvd., Myrtle Beach, SC 29577

    $2,500/Mo
    1,000 sqft

    Ground-floor suite combines an open sales area with a private office and restroom.

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    Flexible Retail Showroom Space
    Flexible Retail Showroom Space

    144 Southport Rd, Spartanburg, SC 29306

    $14.95 SF/Yr
    5,800 sqft  Built 1979
    Highway access

    Flexible commercial space combines a retail showroom with conditioned warehouse capacity and potential outdoor storage.

    Signage
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    Retail Suite with Private Office
    Retail Suite with Private Office

    2126 Highway 9 E, Longs, SC 29568

    $2,000/Mo
    1,188 sqft

    HC-zoned space combines an open-plan area with a restroom and rear storage.

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    Oceanfront Restaurant with Patio
    Oceanfront Restaurant with Patio

    706 North Ocean Blvd. #Unit D, Myrtle Beach, SC 29577

    $6,700/Mo
    2,680 sqft

    The leased premises include restaurant furnishings, bar equipment, and a functioning kitchen with ventilation hood.

    Commercial hood  Patio  Equipment included  Furnished
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    In-Line Retail Suite
    In-Line Retail Suite

    10729 Ocean Highway, Pawleys Island, SC 29585

    $2,888/Mo
    1,083 sqft

    GC-zoned space is positioned at Ocean Highway and Professional Lane within a dining and shopping center.

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    Restaurant Space with Full Bar
    Restaurant Space with Full Bar

    10185A Ocean Hwy, Pawleys Island, SC 29585

    $4,278/Mo
    4,278 sqft  146 seats

    The dining room accommodates a substantial guest count, with a transferable liquor license available to the incoming operator.

    Liquor license
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    Medical Office Suite
    Medical Office Suite

    710 21st Ave. N, Myrtle Beach, SC 29577

    $2,410/Mo
    1,157 sqft  0.16 acres

    A medical and professional office unit is available within a multi-building office park.

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