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    Orangeburg, SC
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    Orangeburg, SC Commercial Real Estate for Lease

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    Santee, SC Swansea, SC Gaston, SC
    16 listings
    Freestanding Restaurant with Parking
    $17 SF/Yr
    Freestanding Restaurant with Parking

    1490 Chestnut Street, Orangeburg, SC 29115

    Second-generation restaurant opportunity in a freestanding building with 46 on-site parking spaces and B-1 zoning.
    • Freestanding former Shoney’s restaurant building ideal for 2nd‑generation restaurant use
    • Located on Orangeburg’s primary commercial corridor adjacent to Planet Fitness and anchored shopping centers
    • 46 on‑site parking spaces for customers and staff
    • Zoned General Business District (B‑1), City of Orangeburg
    • Year built: 1979
    Updated: Jun 7
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    Retail Space with Drive-Thru
    Contact for pricing
    10,725 SF
    Retail Space with Drive-Thru

    1535 John C Calhoun, Orangeburg, SC

    Former CVS space with drive-thru, outparcel to WalMart.
    • Outparcel to a WalMart Neighborhood Market
    • Former CVS with drive thru, offering ~10,725 SF
    • Located on the hard corner of John C. Calhoun Drive at Stonewall Jackson Street
    • Prominent Pylon Sign with Digital Reader Board
    • Access on John C. Calhoun and Stonewall Jackson
    Updated: Nov 5, 2025
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    Industrial Outdoor Storage with Office
    $15 SF/Yr
    Industrial Outdoor Storage with Office

    10 acre industrial site with 7,040 SF office.

    625 Five Chop Rd, Orangeburg, SC

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    Orangeburg Warehouse and Distribution Space
    Contact for pricing
    213,093 SF
    Orangeburg Warehouse and Distribution Space

    213,093 SF warehouse and distribution space available for lease.

    821 State Ct, Orangeburg, SC

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    Retail Space Near Walmart
    Contact for pricing
    1,500 SF
    Retail Space Near Walmart

    Retail space available in shadow-anchored shopping center.

    2805-2831 North Rd, Orangeburg, SC

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    Orangeburg Flex/Industrial Space Available
    $5 SF/Yr
    60,000 SF
    Orangeburg Flex/Industrial Space Available

    60000 SF flex/industrial space for lease in Orangeburg.

    201 Regional Pkwy, Orangeburg, SC

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    Orangeburg Warehouse Space Available
    Contact for pricing
    50,000 SF
    Orangeburg Warehouse Space Available

    50,000 SF warehouse space available immediately in Orangeburg, South Carolina.

    2850 Magnolia St, Orangeburg, SC

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    Retail Space in Orangeburg, SC
    Contact for pricing
    4,625 SF
    Retail Space in Orangeburg, SC

    Retail space available for lease in Orangeburg, South Carolina.

    437 Stonewall Jackson Street Southwest, Orangeburg, SC

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    Retail Space in Orangeburg
    Contact for pricing
    524 SF
    Retail Space in Orangeburg

    Retail space available for lease in Orangeburg, SC.

    1350 Grove Park Dr, Orangeburg, SC

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    Orangeburg Warehouse Space Available
    Contact for pricing
    167,000 SF
    Orangeburg Warehouse Space Available

    167,000 SF warehouse space for rent in Orangeburg.

    255 Millenium Dr, Orangeburg, SC

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    Industrial Build to Suit Opportunity
    Contact for pricing
    167,000 SF
    Industrial Build to Suit Opportunity

    Industrial build to suit opportunity with ±167,000 SF available.

    147 Millenium Dr, Orangeburg, SC 29115

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    Orangeburg Commercial Property for Lease
    Contact for pricing
    Orangeburg Commercial Property for Lease

    Commercial property available for lease in Orangeburg, South Carolina.

    Magnolia Village Parkway @ North Rd (US 178), Orangeburg, SC 29118

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    Retail Space on Hwy 178
    Contact for pricing
    11,700 SF
    Retail Space on Hwy 178

    Retail opportunities in high-growth corridor near major retailers.

    2580 North Rd, Orangeburg, SC

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    Restaurant Space Available For Rent
    $10 SF/Yr
    6,000 SF
    Restaurant Space Available For Rent

    Restaurant and retail spaces available for rent.

    1214 St Matthews Rd NE, Orangeburg, SC 29118

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    Orangeburg Office Space Available
    Contact for pricing
    1,829 SF
    Orangeburg Office Space Available

    Office space for rent in Orangeburg, South Carolina.

    1175 Cook Rd, Orangeburg, SC

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    Retail Space in Grove Park
    Contact for pricing
    Retail Space in Grove Park

    Retail spaces available in a busy Orangeburg shopping center.

    1370 Chestnut St, Orangeburg, SC 29115

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    Based on your search, we've compiled 63 Potential Opportunities for your consideration. Besides 16 Active listings in Orangeburg, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 43 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Industrial Space Near Major Ports
    Contact for pricing
    23,860 SF
    Industrial Space Near Major Ports

    Industrial spaces for lease near I-95, I-26, Savannah, and Charleston.

    4826 U.S. 78, Saint George, SC

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    Port 95 Business Park
    Contact for pricing
    978,805 SF
    Port 95 Business Park

    Industrial spaces for lease in Port 95 Business Park.

    4826 US 78, Saint George, SC

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    Modern Industrial Warehouse Near I-26
    $7 SF/Yr
    50,000 SF
    Modern Industrial Warehouse Near I-26

    50,000 SF warehouse with convenient I-26 access.

    36 Sirens Ln, Gaston, SC

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    Industrial Space Available for Sublease
    Contact for pricing
    202,000 SF
    Industrial Space Available for Sublease

    Up to 202,000 SF available for sublease in Gaston, SC.

    115 15th St, Gaston, SC

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    Similar Spaces for Sale in Orangeburg, SC

    Consider Similar Space for Sale. We found 43 Spaces matching your search parameters.

    Orangeburg Commercial Property with Warehouse
    $249,900
    6,000 SF
    Orangeburg Commercial Property with Warehouse

    Two buildings ideal for office, retail, or warehouse use.

    2874 Bamberg Road, Orangeburg, SC 29115

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    6-Acre Industrial-Zoned Land Parcel
    $100,000
    6.02 Acres
    6-Acre Industrial-Zoned Land Parcel

    Expansive industrial-zoned land parcel for development, investment, or business expansion.

    290 Ashwood Street SE, Orangeburg, SC 29115

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    Multi-Entrance Office Building
    $180,000
    1,750 SF
    Multi-Entrance Office Building

    Office building with multiple entrances, eight rooms, and separate HVAC systems for flexible tenant or owner use.

    495 Dantlzer Street, Orangeburg, SC 29115

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    Orangeburg Commercial Land For Sale
    $375,000
    12.46 Acres
    Orangeburg Commercial Land For Sale

    12.46 acre commercial land parcel in prime Orangeburg location.

    0 Whittaker Parkway, Orangeburg, SC 29115

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    Orangeburg Land Tract For Sale
    $215,000
    48.00 Acres
    Orangeburg Land Tract For Sale

    48 acre tract suitable for recreation, hunting, or agriculture.

    Mahogany Lane, Orangeburg, SC 29115

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    Leased Retail Center For Sale
    $699,500
    5,000 SF
    Leased Retail Center For Sale

    5,000 SF fully leased retail center in Orangeburg, SC.

    1260 Ridgewood Dr, Orangeburg, SC 29118

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    Orangeburg Commercial Land For Sale
    $225,000
    8.58 Acres
    Orangeburg Commercial Land For Sale

    Wooded commercial land available in Orangeburg, South Carolina.

    0 Charleston Highway, Orangeburg, SC 29115

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    Commercial Land with Highway Frontage
    $195,000
    3.49 Acres
    Commercial Land with Highway Frontage

    Commercial land with significant frontage and utilities in Orangeburg, SC.

    TBD Magnolia Street, Orangeburg, SC 29118

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    Orangeburg, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Orangeburg, SC with 16 listings featured on our commercial real estate exchange. The current inventory includes 66,000 square feet of properties with an estimated lease value of $15 SF/Yr.

    Estimated lease rates for Commercial real estate in Orangeburg, SC begin at $5 SF/Yr, with an average of $7 SF/Yr and extend to $10 SF/Yr.
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