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    Simpsonville, SC
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    Simpsonville, SC Commercial Real Estate for Lease

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    Greenville, SC Fountain Inn, SC Mauldin, SC
    30 results
    Historic Downtown Simpsonville Office Space
    $5,084/Mo

    Historic Downtown Simpsonville Office Space

    312 S Main Street, Simpsonville, SC 29681

    Charming office space in historic downtown Simpsonville with ample parking.

    • Prime location in Historic Downtown Simpsonville with excellent visibility.
    • Elegantly finished reception area.
    • Five potential offices, including one suitable for a conference room.
    • Full kitchen and full bathroom.
    • Ample parking with approximately 12‑14 spaces.
    Updated: Feb 6
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    Simpsonville Office Suite for Rent
    $18 SF/Yr
    2,875 SF

    Simpsonville Office Suite for Rent

    419 Main St, Simpsonville, SC

    Office suite with ample parking and convenient highway access.

    • Convenient access to I‑385 & downtown Simpsonville
    • ±2,875 SF office suite with 8 spacious offices
    • ±50 parking spaces
    • Large reception/lobby and kitchenette
    • Zoned BL City of Simpsonville
    Updated: Nov 24, 2025
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    Simpsonville Flex Space Available
    $13 SF/Yr

    Simpsonville Flex Space Available

    Flex space available just outside of downtown Simpsonville, South Carolina.

    1002 Old Stage Rd, Simpsonville, SC 29681
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    Simpsonville Commercial Land For Lease
    Contact for pricing

    Simpsonville Commercial Land For Lease

    0.75 AC parcel on NE Main Street available for ground lease.

    637 NE Main St, Simpsonville, SC 29681
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    Retail Space on Main Street
    $18 SF/Yr
    1,000 SF

    Retail Space on Main Street

    Retail space in well-maintained center, prime Simpsonville location.

    1016-1032 NE Main St, Simpsonville, SC
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    Simpsonville Office Space For Rent
    $14 SF/Yr
    3,150 SF

    Simpsonville Office Space For Rent

    Office space available for lease in Simpsonville, South Carolina.

    1027 South St, Simpsonville, SC
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    Retail Space Near Fairview Road
    $28 SF/Yr
    838 SF

    Retail Space Near Fairview Road

    Retail space available near major retailers and I-385.

    3907 Grandview Dr, Simpsonville, SC
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    Simpsonville Warehouse Space Available
    $4 SF/Yr
    126,261 SF

    Simpsonville Warehouse Space Available

    Large industrial warehouse space for lease in Simpsonville, SC.

    1224 Old Stage Rd, Simpsonville, SC
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    Retail Spaces in Simpsonville Center
    Contact for pricing

    Retail Spaces in Simpsonville Center

    Retail spaces for lease in ALDI-anchored shopping center.

    655 Fairview Road |, Simpsonville, SC 29680
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    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
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    Simpsonville Flex Space For Rent
    Contact for pricing
    24,635 SF

    Simpsonville Flex Space For Rent

    Flex space featuring warehouses, shops, and office space available for lease.

    514 Palmetto Dr, Simpsonville, SC 29681
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    Simpsonville Office Space Available
    $19 SF/Yr
    12,463 SF

    Simpsonville Office Space Available

    Office space available for lease in Simpsonville, SC.

    100 Allawood Ct, Simpsonville, SC
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    Beck Plaza
    $15 SF/Yr

    Beck Plaza

    1,100 SF Retail Building

    1028 NE Main Street, Simpsonville, SC 29681
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    Industrial Property with Storage Shed
    Contact for pricing
    19,253 SF

    Industrial Property with Storage Shed

    Industrial property featuring drive-in bays, dock doors, and storage shed.

    122 Pride Dr, Simpsonville, SC 29681
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    Simpsonville Warehouse Space Available
    Contact for pricing
    146,367 SF

    Simpsonville Warehouse Space Available

    146,367 sqft warehouse/industrial space for lease in Simpsonville, SC.

    East Standing Springs Road, Simpsonville, SC 29680
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    Simpsonville Warehouse Space Available
    $5 SF/Yr
    30,000 SF

    Simpsonville Warehouse Space Available

    30,000 SF warehouse space for lease in Simpsonville.

    1102 Old Stage Rd, Simpsonville, SC
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    Simpsonville Warehouse Space Available
    $6 SF/Yr
    30,000 SF

    Simpsonville Warehouse Space Available

    30,000 square foot warehouse space for rent in Simpsonville.

    3303 N Industrial Dr, Simpsonville, SC
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    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF

    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681
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    Simpsonville Office Space For Rent
    $32 SF/Yr
    5,904 SF

    Simpsonville Office Space For Rent

    5,904 SF office space available for lease.

    220 Scuffletown Rd, Simpsonville, SC
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    Retail Space in Growing Area
    Contact for pricing
    7,900 SF

    Retail Space in Growing Area

    Retail property in Simpsonville, part of the Greenville-Mauldin-Easley MSA.

    914 W Georgia Rd, Simpsonville, SC
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    Simpsonville Industrial Space Available
    Contact for pricing
    1,525 SF

    Simpsonville Industrial Space Available

    Industrial space available for rent in Simpsonville, South Carolina.

    222 Ladean Ct, Simpsonville, SC 29680
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    Prime Retail Corridor Land Lease
    $3,750/Mo

    Prime Retail Corridor Land Lease

    Land lease in high-growth Greenville suburb with strong retail.

    699 Fairview Rd, Simpsonville, SC
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    Publix-Anchored Shopping Center Space
    Contact for pricing
    900 SF

    Publix-Anchored Shopping Center Space

    Retail space in a high-growth, affluent Simpsonville area.

    2700 Woodruff Rd, Simpsonville, SC
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    Industrial Single Tenant Space
    Contact for pricing
    1,600 SF

    Industrial Single Tenant Space

    Industrial single tenant property available for rent.

    1029 Old Stage Rd, Simpsonville, SC, Simpsonville, SC 29681
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    Simpsonville, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Simpsonville, SC with 30 listings featured on our commercial real estate exchange. The current inventory includes 221,091 square feet of properties with an estimated lease value of $170 SF/Yr.

    Estimated lease rates for Commercial real estate in Simpsonville, SC begin at $4 SF/Yr, with an average of $15 SF/Yr and extend to $32 SF/Yr.
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    Most Searched ZIP Codes in Simpsonville, SC

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    • 29680

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