Simpsonville, SC Commercial Real Estate for Lease

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25 properties
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New Construction Retail Space
Updated: Jun 29
New Construction Retail Space

301 N Main St, Simpsonville, SC 29681

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8,361 sqft
Up to 8,361 SF of flexible retail space available for lease in downtown Simpsonville, SC
New construction project (year built: 2027) off N Main Street with strong visibility to 20,200 VPD
Great co‑tenancy with Eggs Up Grill and NY Butcher Shop
Convenient access to approximately 60 parking spaces
Flexible SF available based on the right tenant use
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Historic Mill Office Units
Updated: Jun 25
Historic Mill Office Units

300 South St, Simpsonville, SC 29681

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8,082 sqft
±8,082 SF of office space available across the first floor and mezzanine
±7,068 SF first‑floor open‑concept area
±1,014 SF mezzanine with three private offices and a breakroom
First floor includes a front desk, three individual rooms, open area, and two restrooms
Outdoor patio space included
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Second-Generation Medical Office
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

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7,880 sqft

Located near Fairview Road with convenient access to I-385.

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Simpsonville Retail Space For Lease
Simpsonville Retail Space For Lease

721 SE Main Street, Simpsonville, SC 29680

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7,500 sqft

Up to 7,500 SF retail space in Simpsonville, SC.

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Retail Space with Drive-Through
Retail Space with Drive-Through

676 Fairview Road, Simpsonville, SC 29680

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3,800 sqft

Existing pickup infrastructure and multiple access points support a customer-oriented retail operation.

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Retail Space with Pylon Signage
Retail Space with Pylon Signage

2607 Woodruff Rd, Simpsonville, SC 29681

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3,485 sqft

Retail space available with pylon signage and multiple ingress/egress points, including dedicated signalized access on Woodruff Road.

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Newly Renovated Office Space
Newly Renovated Office Space

205 New Harrison Bridge Road, Simpsonville, SC 29680

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1,425 sqft 5.00 AC lot

Newly renovated office space with a fenced laydown yard for outdoor storage.

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High-Clear Warehouse
High-Clear Warehouse

707 E Standing Springs Rd, Simpsonville, SC 29680

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146,367 sqft

Large industrial warehouse with dock access, drive-in loading, LED lighting, and ESFR fire suppression.

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Class A Industrial Distribution Center
Class A Industrial Distribution Center

2835 Kemet Way, Simpsonville, SC 29681

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215,460 sqft

New industrial distribution facility offers modern functionality and institutional-quality construction with strong interstate connectivity.

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Warehouse with Office Space
Warehouse with Office Space

502 Palmetto Dr, Simpsonville, SC 29681

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18,000 sqft 1.50 AC lot

18,000 SF warehouse with suspended gas heat, heavy 3-phase power, docks and drive-ins, plus 3,000 SF office.

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Retail Space with Signage Availability
Retail Space with Signage Availability

655 Fairview Rd, Simpsonville, SC 29680

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7,204 sqft

Retail space available in a Fairview Road submarket near a lighted intersection and major interstate access.

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Simpsonville Flex Space Available
Simpsonville Flex Space Available

1002 Old Stage Rd, Simpsonville, SC 29681

$13.50 SF/Yr

Flex space available just outside of downtown Simpsonville, South Carolina.

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Retail Spaces in Simpsonville Center
Retail Spaces in Simpsonville Center

655 Fairview Road |, Simpsonville, SC 29680

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53 sqft

Retail spaces for lease in ALDI-anchored shopping center.

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Subdividable Retail Space
Subdividable Retail Space

721 SE Main St, Simpsonville, SC 29681

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7,500 sqft

Retail space for lease near I-385 and Fairview Rd, offered alongside Pro-Fitness Gym.

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Simpsonville Warehouse Space Available
Simpsonville Warehouse Space Available

East Standing Springs Road, Simpsonville, SC 29680

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146,367 sqft

146,367 sqft warehouse/industrial space for lease in Simpsonville, SC.

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Simpsonville Industrial Buildings For Lease
Simpsonville Industrial Buildings For Lease

122 Pride Dr |, Simpsonville, SC 29681

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39 sqft

Multiple industrial buildings for lease on approximately 8.5 usable acres.

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Retail Space in Simpsonville
Retail Space in Simpsonville

107 Northeast Main Street, Simpsonville, SC

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3,000 sqft 2.35 AC lot

Retail space available for lease in Simpsonville, SC.

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Industrial Property with Storage Shed
Industrial Property with Storage Shed

122 Pride Dr, Simpsonville, SC 29681

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19,253 sqft

Industrial property featuring drive-in bays, dock doors, and storage shed.

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Simpsonville Warehouse Space Available
Simpsonville Warehouse Space Available

1224 Old Stage Rd, Simpsonville, SC

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126,261 sqft 17.75 AC lot

Large industrial warehouse space for lease in Simpsonville, SC.

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334,000 SF Office Building For Lease
334,000 SF Office Building For Lease

300 South St, Simpsonville, SC 29681

$19 SF/Yr

334,000 SF Office Building For Lease

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Beck Plaza
Beck Plaza

1028 NE Main Street, Simpsonville, SC 29681

$15 SF/Yr

1,100 SF Retail Building

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Wedding Venue Park with Covered Pavilion
Wedding Venue Park with Covered Pavilion

206 Ladean Court, Simpsonville, SC 29680

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0.74 AC lot

A 0.74-acre wedding venue park featuring a covered pavilion, commissary kitchen access, and on-site parking.

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Warehouse with Truck Doors
Warehouse with Truck Doors

3054 Fork Shoals Rd, Simpsonville, SC 29680

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60,000 sqft

Industrial warehouse offering truck access, drive-in loading, and additional laydown area.

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0 Bridgeway
0 Bridgeway

0 Bridgeway Simpsonville, SC 29681, Simpsonville, SC 29681

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±6,197 SF of office space availalble

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Simpsonville, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Simpsonville, SC with 25 listings featured on our commercial real estate exchange. The current inventory includes 793,637 square feet of properties with an estimated lease value of $47.50.

Estimated lease rates for Commercial real estate in Simpsonville, SC begin at $13.50 SF/Yr, with an average of $15.83 SF/Yr and extend to $19 SF/Yr.
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