Simpsonville, SC Commercial Real Estate for Lease

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41 properties
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Former Bank Drive-Thru Building
Updated: Jun 23
Former Bank Drive-Thru Building

124 NE Main Street, Simpsonville, SC 29680

$22.50 SF/Yr
2,200 sqft
±2,200 SF former bank building available for lease
Former bank building on Main Street in Simpsonville, SC
Ample onsite parking for customers and staff
Separate drive‑thru included and could be utilized by the tenant
Multiple points of ingress/egress
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New Construction Retail Space
Updated: Jun 29
New Construction Retail Space

301 N Main St, Simpsonville, SC 29681

Contact for pricing
8,361 sqft
Up to 8,361 SF of flexible retail space available for lease in downtown Simpsonville, SC
New construction project (year built: 2027) off N Main Street with strong visibility to 20,200 VPD
Great co‑tenancy with Eggs Up Grill and NY Butcher Shop
Convenient access to approximately 60 parking spaces
Flexible SF available based on the right tenant use
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Retail Space in Shopping Center
Retail Space in Shopping Center

659 Fairview Road, Simpsonville, SC 29680

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4,486 sqft

Retail space within a shopping center with Business-General zoning and access via a signalized intersection.

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Retail Space with Parking
Retail Space with Parking

301 N Main St, Simpsonville, SC 29681

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8,361 sqft

Flexible sizing is available alongside co-tenancy with Eggs Up Grill and NY Butcher Shop.

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Flex Space with Dock Access
Flex Space with Dock Access

201 Greer Drive, Simpsonville, SC 29681

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18,000 sqft 1.50 AC lot

Industrial facility combines warehouse and office areas with heavy power, loading infrastructure, and shop support spaces.

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Historic Mill Office Units
Historic Mill Office Units

300 South St, Simpsonville, SC 29681

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8,082 sqft

NNN office availability combines open-plan workspace, private rooms, restrooms, a mezzanine, and outdoor patio space.

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Former Office Building Lease Opportunity
Former Office Building Lease Opportunity

118 NE Main St, Simpsonville, SC 29681

$15 SF/Yr

Lease a former office building with an 18-month short-term option on Main Street in Simpsonville.

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Second-Generation Medical Office
Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

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7,880 sqft

Located near Fairview Road with convenient access to I-385.

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Retail Space with Drive-Through
Retail Space with Drive-Through

676 Fairview Road, Simpsonville, SC 29680

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3,800 sqft

Existing pickup infrastructure and multiple access points support a customer-oriented retail operation.

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Retail Space with Pylon Signage
Retail Space with Pylon Signage

2607 Woodruff Rd, Simpsonville, SC 29681

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3,485 sqft

Retail space available with pylon signage and multiple ingress/egress points, including dedicated signalized access on Woodruff Road.

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Newly Renovated Office Space
Newly Renovated Office Space

205 New Harrison Bridge Road, Simpsonville, SC 29680

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1,425 sqft 5.00 AC lot

Newly renovated office space with a fenced laydown yard for outdoor storage.

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End-Unit Commercial Kitchen
End-Unit Commercial Kitchen

121 Webb St, Simpsonville, SC 29681

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1,000 sqft

Open-plan suite with one restroom, shared parking, and Business General zoning in Greenville County.

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Class A Industrial Distribution Center
Class A Industrial Distribution Center

2835 Kemet Way, Simpsonville, SC 29681

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215,460 sqft

New industrial distribution facility offers modern functionality and institutional-quality construction with strong interstate connectivity.

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Office Suite with Multiple Offices
Office Suite with Multiple Offices

131 Southeast Main Street, Simpsonville, SC 29681

$7,549/Mo

Office space offering up to eight offices, a functional kitchen, and 13 parking spots.

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Warehouse with Office Space
Warehouse with Office Space

502 Palmetto Dr, Simpsonville, SC 29681

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18,000 sqft 1.50 AC lot

18,000 SF warehouse with suspended gas heat, heavy 3-phase power, docks and drive-ins, plus 3,000 SF office.

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Simpsonville Retail Space For Lease
Simpsonville Retail Space For Lease

721 SE Main Street, Simpsonville, SC 29680

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17,500 sqft

Up to 7,500 SF retail space available for lease.

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Retail Space with Signage Availability
Retail Space with Signage Availability

655 Fairview Rd, Simpsonville, SC 29680

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7,204 sqft

Retail space available in a Fairview Road submarket near a lighted intersection and major interstate access.

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Simpsonville Retail Space For Lease
Simpsonville Retail Space For Lease

721 SE Main St, Simpsonville, SC 29681

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7,500 sqft

Up to 7,500 SF retail space in Simpsonville, SC.

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Simpsonville Flex Space Available
Simpsonville Flex Space Available

1002 Old Stage Rd, Simpsonville, SC 29681

$13.50 SF/Yr

Flex space available just outside of downtown Simpsonville, South Carolina.

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Retail Spaces in Simpsonville Center
Retail Spaces in Simpsonville Center

655 Fairview Road |, Simpsonville, SC 29680

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53 sqft

Retail spaces for lease in ALDI-anchored shopping center.

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Subdividable Retail Space
Subdividable Retail Space

721 SE Main St, Simpsonville, SC 29681

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7,500 sqft

Retail space for lease near I-385 and Fairview Rd, offered alongside Pro-Fitness Gym.

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Simpsonville Warehouse Space Available
Simpsonville Warehouse Space Available

East Standing Springs Road, Simpsonville, SC 29680

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146,367 sqft

146,367 sqft warehouse/industrial space for lease in Simpsonville, SC.

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Two-Story Office Units
Two-Story Office Units

419-421 SE Main St, Simpsonville, SC 29681

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Lease space across two office buildings with Main Street exposure, monument signage, and on-site parking.

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Simpsonville Flex Space For Rent
Simpsonville Flex Space For Rent

514 Palmetto Dr, Simpsonville, SC 29681

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24,635 sqft 5.10 AC lot

Flex space featuring warehouses, shops, and office space available for lease.

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Simpsonville, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Simpsonville, SC with 41 listings featured on our commercial real estate exchange. The current inventory includes 709,824 square feet of properties with an estimated lease value of $85.

Estimated lease rates for Commercial real estate in Simpsonville, SC begin at $13.50 SF/Yr, with an average of $17 SF/Yr and extend to $22.50 SF/Yr.
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