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Oconee County, SC Commercial Real Estate for Lease

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18 results
Move-in Ready Office Space
$2,200 /Mo

Move-in Ready Office Space

111 N Earle Street, Walhalla, SC 29691

Well-maintained office space in established professional park, ready for occupancy.

  • Highway Commercial zoning and location just off Hwy 28, ideal for establishing a professional office.
  • Potential for subdivision into multiple businesses with mirrored floor plan, two front doors with ramp access, and four meter bases.
  • Features eight private offices, reception area, breakroom, and front office.
  • 1200 sq ft unfinished basement, plumbed for an additional bathroom, offering potential for more offices or living space.
  • Move‑in ready and well‑maintained office space in an established professional park.
Updated: Jul 10, 2025
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Seneca Office Space For Lease
$1,500 /Mo

Seneca Office Space For Lease

865 Old Clemson Highway, Seneca, SC 29678

Two-level office building suitable for various businesses, near Clemson.

  • Suitable for various business types, including medical/dental offices.
  • Two levels with separate entrances and restrooms, offering flexible leasing options (entire building or individual floors).
  • Located in close proximity to Clemson and Seneca.
  • Lower level features 3 offices, conference room, and reception area (Lease: $1,750.00 NNN).
  • Upper level offers 5 offices and a reception area (Lease: $2,900.00 NNN).
Updated: Mar 28, 2025
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Office Space Near Clemson
$4,000 /Mo

Office Space Near Clemson

Two-level office building suitable for various businesses, near Clemson.

865 Old Clemson Highway, Seneca, SC 29678
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Fair Play Warehouse Space Available
$4 SF/Yr
9,100 SF

Fair Play Warehouse Space Available

9,100 SF warehouse space for lease in Fair Play.

650 E Fairplay Blvd, Fair Play, SC 29643
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Office Space in Seneca, SC
$2,500 /Mo

Office Space in Seneca, SC

Commercial office space available for lease in Seneca, South Carolina.

865 Old Clemson Highway, Seneca, SC 29678
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Seneca Retail/Office Space Available
$1,700 /Mo
712 SF

Seneca Retail/Office Space Available

Retail/office space for lease in Seneca, SC. Renovated and visible.

1109 Jennings Ave Unit A, Seneca, SC 29768
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Remodeled Restaurant Space on Main
$2,000 /Mo

Remodeled Restaurant Space on Main

Prime restaurant property in a high-traffic, growing tourist area.

100 -102 W Main Street, Walhalla, SC 29691
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Retail Space Near Clemson University
$21 SF/Yr
43,000 SF

Retail Space Near Clemson University

End-cap retail space with drive-thru potential near Clemson University.

1085 Old Clemson Highway, Seneca, SC 29672
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Retail Opportunity Near Walmart
Contact for pricing

Retail Opportunity Near Walmart

Retail space available for lease near Walmart and hospital.

Seneca, SC 29678
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Retail Property on Main Corridor
$11 SF/Yr
7,250 SF

Retail Property on Main Corridor

Retail property with excellent visibility and heavy traffic.

1592 Sandifer Blvd, Seneca, SC
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Retail Opportunity Near Walmart
Contact for pricing

Retail Opportunity Near Walmart

Retail space available for lease, GL, or build-to-suit.

1637 Sandifer Blvd, Seneca, SC
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West Union Office Space Available
$10 SF/Yr
4,800 SF

West Union Office Space Available

Office space available for rent in West Union, SC.

153 Scenic Plaza Dr, West Union, SC
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Seneca Office/Retail Space Available
$15 SF/Yr
4,800 SF

Seneca Office/Retail Space Available

Office and retail spaces for lease in Seneca, South Carolina.

12019 North Radio Station Rd, Seneca, SC
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Westminster Commercial Property For Rent
Contact for pricing

Westminster Commercial Property For Rent

Commercial property available for rent in Westminster, South Carolina.

0 East Main and S Piedmont ST, Westminster, SC 29693
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Restaurant Space Near Oconee Medical
Contact for pricing
16,000 SF

Restaurant Space Near Oconee Medical

1,600 SF 2nd Gen Restaurant Space Available For Rent.

201-273 Applewood Center Pl, Seneca, SC
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Land Near Oconee Medical Center
Contact for pricing

Land Near Oconee Medical Center

Commercial land for rent near medical center and Clemson University.

15516 Wells Hwy, Seneca, SC
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Retail Space Near Oconee Medical
Contact for pricing
1,600 SF

Retail Space Near Oconee Medical

Retail space available near Oconee Medical Center and Clemson University.

101 Applewood Center Pl, Seneca, SC
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Dominant Power Center For Rent
Contact for pricing
245,000 SF

Dominant Power Center For Rent

245,000 SF power center anchored by Belk, Hobby Lobby, etc.

201 Applewood Center Pl, Seneca, SC 29678
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Based on your search, we've compiled 102 Potential Opportunities for your consideration. Besides 18 Active listings in Oconee County, SC, we suggest exploring alternatives. Similar 84 Properties for Sales.

Explore Similar Spaces for Sale in Oconee County, SC

Consider Similar Space for Sale. We found 84 Spaces matching your search parameters.

Iconic Walhalla Space For Sale
$500,000
0.12 Acres

Iconic Walhalla Space For Sale

Versatile 2200+ sqft space suitable for retail, events, or office.

230 E Main Street, Walhalla, SC 29691
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Renovated Commercial Space on Main
$490,000
0.06 Acres

Renovated Commercial Space on Main

Prime commercial space ideal for retail, office, or restaurant.

212 E Main Street, Walhalla, SC 29691
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Walhalla Retail Property For Sale
$499,900
0.41 Acres

Walhalla Retail Property For Sale

Prime retail property in Walhalla with income-producing potential.

104 -106 W Main Street, Walhalla, SC 29691
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Downtown Walhalla Investment Opportunity
$399,900

Downtown Walhalla Investment Opportunity

Prime commercial building in downtown Walhalla with immediate income.

206 E Main Street, Walhalla, SC 29691
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Move-in Ready Office Space
$349,900
0.35 Acres

Move-in Ready Office Space

Well-maintained office space in established park, ideal for professionals.

111 N Earle Street, Walhalla, SC 29691
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West Union Shopping Center Investment
$4,200,000
6.72 Acres

West Union Shopping Center Investment

Income-producing shopping center on 6.72 acres with expansion potential.

128 Foothills Center Drive, West Union, SC 29696
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Oconee County, SC Commercial real estate Leasing Opportunities Market Analysis

Explore Commercial real estate leasing options in Oconee County, SC with 18 listings featured on our commercial real estate exchange. The current inventory includes 4,402,504,660 square feet of properties with an estimated lease value of $29 SF/Yr.

Estimated lease rates for Commercial real estate in Oconee County, SC begin at $0.69 SF/Yr, with an average of $4 SF/Yr and extend to $15 SF/Yr.
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