Spartanburg County, SC Commercial real estate for Rent & Lease

Updated: Jun 21

Renovated Furnished Office Units

792 John B White Sr Boulevard, Spartanburg, SC 29306

$2,808/Mo

0.56 AC lot

1,230‑square‑foot furnished office property
Recently renovated with updated lighting, LVP, carpet, and contemporary finishes
Flexible office layout with central heating and central air
0.56‑acre site with parking lot and porch
Access to Interstate 26 and Interstate 85

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Updated: Sep 4

Freestanding Drive-Through Restaurant

497 E Blackstock Road, Spartanburg, SC 29301

$6,000/Mo

0.65 AC lot

Approximately 3,200 SF freestanding restaurant building
0.65‑acre parcel with on‑site parking
Drive‑through functionality with multiple access points
Commercial kitchen and walk‑in cooler/freezer
Dining and customer‑service areas already configured

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Modern Medical Office Space

391 Serpentine Drive, Spartanburg, SC 29303

$1,156/Mo

4,387 sqft

Modern medical suites with patient-care areas, elevator access, on-site parking, and proximity to Spartanburg Regional Medical Hospital.

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Retail/Flex Building at Signalized Corner

1321 Union St, Spartanburg, SC 29306

$12 SF/Yr

8,400 sqft

A retail-flex building with signalized intersection visibility and road frontage on a high-traffic corridor.

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Industrial Flex Space with Two Buildings

113 Ian Ct, Spartanburg, SC 29306

$12,500/Mo

12,500 sqft 1.95 AC lot

Two-building property combines office areas with warehouse space for flexible business operations.

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Retail Space at Signalized Intersection

1208 Union Street, Spartanburg, SC 29302

$12 SF/Yr

4,000 sqft

Versatile retail space in a shopping center anchored by grocery and ice machine businesses, with substantial road frontage.

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Endcap Flex Space with Dock Door

552 Mayfield Road, Duncan, SC 29334

$9 SF/Yr

6,250 sqft

Endcap flex space available for sublease with one dock door, upgraded LED lighting, and clear height up to 21 feet.

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Flex Space with Conditioned Warehouse

1095 Southport Rd, Spartanburg, SC 29306

$8 SF/Yr

24,000 sqft

Industrial property combining office accommodation with conditioned warehouse and manufacturing space.

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Highway 290 Retail Development Space

1723 East Main Street, Duncan, SC 29334

$40 SF/Yr

9,850 sqft

Retail/office space in growing Duncan market near Highway 290.

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Spartanburg Storefront Retail/Office Space

512 E Main St, Spartanburg, SC 29302

$15 SF/Yr

2,046 sqft

Renovated 2,046 SF retail/office space in downtown Spartanburg.

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Buildout-Ready Anchor Retail Space

116-122 South Main Street, Woodruff, SC 29388

Contact for pricing

14,400 sqft

Buildout-ready shell with flexible configuration for single- or multi-tenant retail use.

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Spartanburg Outdoor Storage Opportunity

220 West Lanford Street, Spartanburg, SC 29302

$4,000/Mo

4 sqft 4.38 AC lot

4.38 AC outdoor storage space for lease in Spartanburg.

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Turnkey Commercial Kitchen with Patio

1802 Drayton Road Suite I, Spartanburg, SC 29307

$23 SF/Yr

Fully equipped kitchen with adjoining patio accommodates restaurant, catering, and specialty food operations.

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Duncan Development Opportunity For Rent

Apple Valley Road, Duncan, SC 29334

$5,670/Mo

4 sqft

4.2 AC development opportunity in Duncan, SC, near I-85.

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Turnkey Commercial Kitchen Space

1802 Drayton Road, Suite 101, Spartanburg, SC 29307

Contact for pricing

2,269 sqft

Restaurant-ready suite with installed cooking equipment, prep infrastructure, and an outdoor patio for dining or events.

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Renovated Retail Space

503 Union St, Spartanburg, SC 29306

Contact for pricing

3,020 sqft

Flexible commercial space is planned for retail, restaurant, or office use.

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Industrial Space in Duncan, SC

925 Berry Shoals Rd, Duncan, SC 29334

$8.50 SF/Yr

28,000 sqft

28,000 SF industrial space for lease near I-85.

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Warehouse with Drive-In Access

501 Southport Rd, Roebuck, SC 29376

Contact for pricing

12,125 sqft 1.64 AC lot

12,125± SF metal warehouse on 1.638 acres with a loading dock, drive-in doors, roll-up doors, and private offices.

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Historic Office Building for Rent

571 East Main Street, Spartanburg, SC 29302

Contact for pricing

4,688 sqft 0.48 AC lot

Renovated historic building with multiple rooms, suited for professional office use, with street parking available.

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Flex Building with Retail Signage

1106 Rutherfordton Hwy 221, Chesnee, SC 29323

Contact for pricing

5,000 sqft

Flex building with 3-phase power and camera/alarm system, currently laid out for retail or service use.

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Enclosed Mall Retail Space

205 W Blackstock Rd, Spartanburg, SC 29301

Contact for pricing

3,306 sqft

Inline retail space within an enclosed mall serving the Spartanburg County market.

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Two-Level Retail Building with Storefront Windows

132 South Main Street, Woodruff, SC 29388

$13 SF/Yr

Restored two-level retail building with oversized storefront windows, offering an inviting main level and versatile interior layout.

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Corner Medical Office Building

108 W RUTHERFORD ST, Landrum, SC 29356

Contact for pricing

2,400 sqft

All-brick medical building offers exam rooms, multiple lobbies, and private parking lot access to two city streets.

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Renovated Flex Warehouse with Yard

608 Shiloh Church Rd, Lyman, SC 29365

Contact for pricing

10,150 sqft 0.80 AC lot

Renovated flex warehouse with 14' clear height, roll-up doors, and an on-site gravel laydown yard for outdoor storage needs.

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Spartanburg County, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Spartanburg County, SC with 260 listings featured on our commercial real estate exchange. The current inventory includes 14,745,883 square feet of properties with an estimated lease value of $223.

Estimated lease rates for Commercial real estate in Spartanburg County, SC begin at $7 SF/Yr, with an average of $13.94 SF/Yr and extend to $40 SF/Yr.

Featured Spartanburg County Real Estate Agencies

Realmo connects you with licensed Spartanburg County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Realty Spartanburg Partners

1707 John B White Sr Blvd, Suite E Spartanburg, SC 29301

Phone: 18645746000

www.kwspartanburg.com

Century 21 Blackwell & Co.

2260 Boiling Springs Road Boiling Springs, SC 29316

Phone: 18645960322

www.century21blackwell.com

Better Homes and Gardens Young & Company

8291 Warren H. Abernathy Highway Spartanburg, SC 29301

Phone: 19706605323

bhgyoung.com