Spartanburg County, SC Commercial real estate for Rent & Lease

Updated: Jun 21

Renovated Furnished Office Units

792 John B White Sr Boulevard, Spartanburg, SC 29306

$2,808/Mo

0.56 AC lot

1,230‑square‑foot furnished office property
Recently renovated with updated lighting, LVP, carpet, and contemporary finishes
Flexible office layout with central heating and central air
0.56‑acre site with parking lot and porch
Access to Interstate 26 and Interstate 85

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Updated: Sep 4

Freestanding Drive-Through Restaurant

497 E Blackstock Road, Spartanburg, SC 29301

$7,000/Mo

0.65 AC lot

Approximately 3,200 SF freestanding restaurant building
0.65‑acre parcel with on‑site parking
Drive‑through functionality with multiple access points
Commercial kitchen and walk‑in cooler/freezer
Dining and customer‑service areas already configured

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Medical Office Space with Drop-Off Area

230 Giles Dr, Boiling Springs, SC 29316

$6,730/Mo

6,730 sqft 1.25 AC lot

Private offices, shared work areas, and a dedicated vehicle drop-off area provide a flexible existing layout.

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Flexible Retail Showroom Space

144 Southport Rd, Spartanburg, SC 29306

$14.95 SF/Yr

5,800 sqft

Flexible commercial space combines a retail showroom with conditioned warehouse capacity and potential outdoor storage.

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Modern Medical Office Space

391 Serpentine Drive, Spartanburg, SC 29303

$1,156/Mo

4,387 sqft

Modern medical suites with patient-care areas, elevator access, on-site parking, and proximity to Spartanburg Regional Medical Hospital.

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Retail Showroom with Signage

146 Southport Road, Spartanburg, SC 29306

$14.95 SF/Yr

3,200 sqft

Retail space combines a customer-facing showroom with back-office and inventory areas for lease.

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Retail/Flex Building at Signalized Corner

1321 Union St, Spartanburg, SC 29306

$12 SF/Yr

8,400 sqft

A retail-flex building with signalized intersection visibility and road frontage on a high-traffic corridor.

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Flex Building with Outdoor Storage

1629 Union Street, Spartanburg, SC 29306

$10.95 SF/Yr

5,000 sqft

New construction pairs a clear-span warehouse with office space and grade-level loading.

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Industrial Flex Space with Two Buildings

113 Ian Ct, Spartanburg, SC 29306

$12,500/Mo

12,500 sqft 1.95 AC lot

Two-building property combines office areas with warehouse space for flexible business operations.

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Corner Medical Office Building

108 W Rutherford St, Landrum, SC 29356

$2,500/Mo

2,400 sqft

All-brick medical building offers exam rooms, multiple lobbies, and private parking lot access to two city streets.

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Retail Space at Signalized Intersection

1208 Union Street, Spartanburg, SC 29302

$12 SF/Yr

4,000 sqft

Versatile retail space in a shopping center anchored by grocery and ice machine businesses, with substantial road frontage.

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Endcap Flex Space with Dock Door

552 Mayfield Road, Duncan, SC 29334

$9 SF/Yr

6,250 sqft

Endcap flex space available for sublease with one dock door, upgraded LED lighting, and clear height up to 21 feet.

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Flex Space with Office

51B Dexter Road, Spartanburg, SC 29303

$11.50 SF/Yr

2,000 sqft

This light-industrial space offers HVAC throughout and the possibility of outdoor storage.

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Flex Space with Conditioned Warehouse

1095 Southport Rd, Spartanburg, SC 29306

$8 SF/Yr

24,000 sqft

Industrial property combining office accommodation with conditioned warehouse and manufacturing space.

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Highway 290 Retail Development Space

1723 East Main Street, Duncan, SC 29334

$40 SF/Yr

9,850 sqft

Retail/office space in growing Duncan market near Highway 290.

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Spartanburg Storefront Retail/Office Space

512 E Main St, Spartanburg, SC 29302

$15 SF/Yr

2,046 sqft

Renovated 2,046 SF retail/office space in downtown Spartanburg.

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Buildout-Ready Anchor Retail Space

116-122 South Main Street, Woodruff, SC 29388

Contact for pricing

14,400 sqft

Buildout-ready shell with flexible configuration for single- or multi-tenant retail use.

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Spartanburg Outdoor Storage Opportunity

220 West Lanford Street, Spartanburg, SC 29302

$4,000/Mo

4 sqft 4.38 AC lot

4.38 AC outdoor storage space for lease in Spartanburg.

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Office Units with Dual Frontage

846 WO Ezell Blvd, Spartanburg, SC 29301

Contact for pricing

3,120 sqft

B4-zoned commercial space near downtown with exposure along two public streets.

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Development-Ready Commercial Land

5831 Reidville Rd, Moore, SC 29369

$11.26 SF/Yr

11 sqft 11.26 AC lot

A development-ready commercial site with access on both Hwy 290 and Reidville Road for a range of retail and outparcel uses.

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Duncan Development Opportunity For Rent

Apple Valley Road, Duncan, SC 29334

$5,670/Mo

4 sqft

4.2 AC development opportunity in Duncan, SC, near I-85.

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Mixed-Use Marketplace with Restaurant Space

1802 Drayton Road, Drayton, SC 29333

$16 SF/Yr

Lease offerings include creative offices, a second-generation restaurant, and event space.

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Turnkey Commercial Kitchen Space

1802 Drayton Road, Suite 101, Spartanburg, SC 29307

Contact for pricing

2,269 sqft

Restaurant-ready suite with installed cooking equipment, prep infrastructure, and an outdoor patio for dining or events.

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Renovated Retail Space

503 Union St, Spartanburg, SC 29306

Contact for pricing

3,020 sqft

Flexible commercial space is planned for retail, restaurant, or office use.

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Spartanburg County, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Spartanburg County, SC with 185 listings featured on our commercial real estate exchange. The current inventory includes 14,251,120 square feet of properties with an estimated lease value of $314.11.

Estimated lease rates for Commercial real estate in Spartanburg County, SC begin at $7 SF/Yr, with an average of $13.09 SF/Yr and extend to $40 SF/Yr.

Featured Spartanburg County Real Estate Agencies

Realmo connects you with licensed Spartanburg County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Realty Spartanburg Partners

1707 John B White Sr Blvd, Suite E Spartanburg, SC 29301

Phone: (864) 574-6000

www.kwspartanburg.com

Century 21 Blackwell & Co.

2260 Boiling Springs Road Boiling Springs, SC 29316

Phone: (864) 596-0322

www.century21blackwell.com

Better Homes and Gardens Young & Company

8291 Warren H. Abernathy Highway Spartanburg, SC 29301

Phone: (970) 660-5323

bhgyoung.com