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    Horry County, SC Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    226 results
    Professional Office Space in Murrells Inlet
    $5,500 /Mo
    3,000 SF

    Professional Office Space in Murrells Inlet

    5187 Horry Dr., Murrells Inlet, SC 29576

    Well-maintained office space with excellent access and visibility.

    • Excellent location in the heart of Murrells Inlet with convenient access to Highway 17.
    • Flexible space: 3,000 SF total, divisible into 1,000 SF and 2,000 SF suites.
    • The 2,000 SF suite features a reception area, conference room, and multiple executive offices with nicely appointed finishes.
    • Tenant Improvement (TI) Allowance available for customization and upfit.
    • Ample on‑site parking and monument signage for excellent visibility.
    Updated: Mar 27
    View details
    Professional Office Space Available
    $3,670 /Mo
    2,000 SF

    Professional Office Space Available

    5187 Horry Dr., Murrells Inlet, SC 29576

    Office space for lease in Murrells Inlet, SC.

    • Prime location in the heart of Murrells Inlet with convenient access to Highway 17 Business and Bypass.
    • Flexible space options: 3,000 SF total, divisible into 1,000 SF and 2,000 SF suites.
    • Well‑designed 2,000 SF suite with reception area, conference room, and executive offices.
    • Tenant Improvement (TI) Allowance available for customization and upfit.
    • Ample on‑site parking and monument signage for excellent visibility.
    Updated: Mar 27
    View details
    Professional Office Space Available
    $3,670 /Mo
    1,000 SF

    Professional Office Space Available

    Office space for lease in Murrells Inlet, South Carolina.

    5187 Horry Dr., Murrells Inlet, SC 29576
    View details
    Versatile Flex Space in Myrtle Beach
    $4,750 /Mo
    4,110 SF

    Versatile Flex Space in Myrtle Beach

    Adaptable commercial space for lease in the Arts & Innovation District.

    716 8th Ave. N, Myrtle Beach, SC 29577
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    Retail Center Renovation in Little River
    $1,913 /Mo
    1,148 SF

    Retail Center Renovation in Little River

    Retail and office spaces available in renovated Little River center.

    4390 Spa Dr., Little River, SC 29566
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    Professional Office Building in Myrtle Beach
    $5,000 /Mo
    2,230 SF

    Professional Office Building in Myrtle Beach

    Well-maintained office building in the heart of Myrtle Beach.

    607 19th Ave. N, Myrtle Beach, SC 29577
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    Office Warehouse in Murrells Inlet
    $3,000 /Mo
    2,200 SF

    Office Warehouse in Murrells Inlet

    Office warehouse space for lease with great location and visibility.

    11772 S Highway 17 Bypass, Murrells Inlet, SC 29576
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    New Flex Development in Murrells
    $3,000 /Mo
    1,625 SF

    New Flex Development in Murrells

    New construction flex space with build-to-suit options available.

    4960 Highway 17, Murrells Inlet, SC 29576
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    Myrtle Beach Office with Restrooms
    $3,710 /Mo
    2,400 SF

    Myrtle Beach Office with Restrooms

    Office space with private executive offices and shared parking.

    2102 Cromley Circle, Myrtle Beach, SC 29577
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    Retail Space in Columbus Plaza
    $1,000 /Mo
    1,000 SF

    Retail Space in Columbus Plaza

    1,000 SF retail space for lease in Myrtle Beach.

    3721 Wesley St., Myrtle Beach, SC 29579
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    Retail Space in Little River
    $3,333 /Mo
    2,000 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River shopping center.

    4390 Spa Dr., Little River, SC 29566
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    Retail Space in Little River
    $1,931 /Mo
    1,159 SF

    Retail Space in Little River

    Retail space available in high-traffic Little River location.

    4390 Spa Dr., Little River, SC 29566
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    Murrells Inlet Office Space
    $2,187 /Mo
    1,250 SF

    Murrells Inlet Office Space

    Multi-tenant office/retail/medical building with 1,250 SF available 4/1/26.

    637 Bellamy Ave., Murrells Inlet, SC 29576
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    Murrells Inlet Office Space
    $1,510 /Mo
    1,250 SF

    Murrells Inlet Office Space

    Second floor office space available in Murrells Inlet, SC.

    637 Bellamy Ave., Murrells Inlet, SC 29576
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    Class A Office Building
    $24,000
    12,000 SF

    Class A Office Building

    Class A office building near amenities, tenants in place.

    601 21st Ave. N, Myrtle Beach, SC 29577
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    Myrtle Beach Industrial Warehouse Space
    $9,750 /Mo
    4,000 SF

    Myrtle Beach Industrial Warehouse Space

    Industrial warehouse with climate control and drive-thru capability for lease.

    3720 Wesley St., Myrtle Beach, SC 29579
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    Class A Office Space Available
    $6,118 /Mo
    2,225 SF

    Class A Office Space Available

    Premium professional office suites available for lease in Myrtle Beach.

    4559 Oleander Dr., Myrtle Beach, SC 29577
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    Class A Office Suites Leasing
    $6,118 /Mo
    2,225 SF

    Class A Office Suites Leasing

    Premium professional office suites available for lease in Myrtle Beach.

    4559 Oleander Dr., Myrtle Beach, SC 29577
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    Medical/Professional Office Near Conway Hospital
    $6,251 /Mo
    5,246 SF

    Medical/Professional Office Near Conway Hospital

    Medical/professional office building near Conway Medical Center with customizable space.

    8028 Myrtle Trace Dr., Conway, SC 29526
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    Class A Office Suites Available
    $4,360 /Mo
    1,539 SF

    Class A Office Suites Available

    Premium office suites in a Class A development for lease.

    4559 Oleander Dr., Myrtle Beach, SC 29577
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    Retail Space on Highway 17
    $8,624 /Mo
    4,500 SF

    Retail Space on Highway 17

    Established retail space with highway frontage in Myrtle Beach.

    10589 N Kings Highway, Myrtle Beach, SC 29572
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    Professional Office Suite in Murrells
    $525 /Mo

    Professional Office Suite in Murrells

    Executive office suite with shared amenities on Highway 17.

    3955 Highway 17 Bypass, Murrells Inlet, SC 29576
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    Class A Office Suites Leasing
    $5,106 /Mo
    1,857 SF

    Class A Office Suites Leasing

    Premium professional office suites in a Class A development.

    4559 Oleander Dr., Myrtle Beach, SC 29577
    View details
    Prime Retail Space in Aynor
    $2,500 /Mo
    1,507 SF

    Prime Retail Space in Aynor

    Versatile 1,507 sq ft retail space in growing Aynor, SC.

    905 N Main St., Aynor, SC 29511
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    Horry County, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Horry County, SC with 226 listings featured on our commercial real estate exchange. The current inventory includes 17,150,094,720 square feet of properties with an estimated lease value of $1,909 /Mo.

    Estimated lease rates for Commercial real estate in Horry County, SC begin at $2 SF/Yr, with an average of $20 SF/Yr and extend to $98 SF/Yr.
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