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    Greenville County, SC Commercial Real Estate for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    563 results
    SC, Greenville - E Stone Avenue
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    Piedmont Commercial Office Space
    $1,650/Mo
    Piedmont Commercial Office Space

    2514 River Road, Piedmont, SC 29673

    1,200 SF office space with high visibility and accessibility.
    • High‑visibility location on a high‑traffic road, ideal for attracting clients and customers.
    • Convenient access to I‑85 highway, facilitating easy commuting for employees and clients.
    • Flexible, customizable 1,200 square foot open layout suitable for various business types.
    • Includes water, trash, and all NNN costs in monthly rent of $1,700.
    • Modern finishes and on‑site parking create a professional and inviting atmosphere.
    Updated: Mar 24
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    Office Studio Suite in Park Square Center
    $1,500/Mo
    Office Studio Suite in Park Square Center

    1322 E Washington Street, Greenville, SC 29607

    Freshly painted rear lower-level office studio with a private bath in a thriving, multi-tenant center.
    • 700 SF office/studio space on the rear lower level at Park Square Center with 1 bath
    • Space is freshly painted and ready for a new tenant
    • Asking $1,500 per month with a 2‑year lease; tenant pays all utilities and provides commercial tenant’s insurance
    • Park Square Center is centrally located in Greenville, SC, blocks from downtown, I‑385, and about 2 miles from Hwy 85
    • Center is leased with tenants including Rocky Creek Dental, llyn Strong Gallery, Peak Performance, Neelys, PT Solutions, Browning Salon, and MJT Designs
    Updated: Jun 3
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    Main Street Professional Office Space
    $550/Mo
    Main Street Professional Office Space

    Newly renovated office spaces overlooking Main Street in Greenville, SC.

    200 N Main Street, Greenville, SC 29601

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    High-Visibility Commercial Site on White Horse
    $3,800/Mo
    2,000 SF
    High-Visibility Commercial Site on White Horse

    One-acre commercial site ideal for auto sales or similar uses.

    4707 White Horse Road, Greenville, SC 29611

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    Historic Downtown Simpsonville Office Space
    $5,084/Mo
    Historic Downtown Simpsonville Office Space

    Charming office space in historic downtown Simpsonville with ample parking.

    312 S Main Street, Simpsonville, SC 29681

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    New Commercial Unit For Lease
    $4,100/Mo
    2,500 SF
    New Commercial Unit For Lease

    Brand new commercial unit with versatile space in Travelers Rest.

    1 Brookside Drive, Travelers Rest, SC 20690

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    Downtown Greenville Office Space Available
    $1,542/Mo
    1,750 SF
    Downtown Greenville Office Space Available

    Office suites available in downtown Greenville, utilities included.

    1010 E North Street, Greenville, SC 29601

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    Specialty Commercial Rental Space
    $2,200/Mo
    Specialty Commercial Rental Space

    Commercially zoned rental property on Memorial Drive in Greer, suited for specialty uses requiring a small site.

    106 Memorial Drive, Greer, SC 29650

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    Furnished Office Space Available
    $585/Mo
    Furnished Office Space Available

    Furnished and unfurnished offices with included utilities and amenities.

    552 Memorial Drive Extension, Greer, SC 29651

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    Millport at Butler
    $129-$5,274/Mo
    Millport at Butler

    Discover many ways to work your way in Millport at Butler

    128 Millport Cir, Unit 200, Greenville, SC 29607

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    NOMA Tower
    $129-$6,037/Mo
    NOMA Tower

    Discover many ways to work your way in NOMA Tower

    220 Main St, Unit 500, Greenville, SC 29601

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    Piedmont Commercial Land For Lease
    $9,000/Mo
    Piedmont Commercial Land For Lease

    6.29 acres with high visibility from I-85.

    Durham Road, Piedmont, SC 29673

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    Prime Midtown Retail Leasing Opportunity
    $23 SF/Yr
    5,000 SF
    Prime Midtown Retail Leasing Opportunity

    Newly renovated retail space in prime Greenville location.

    1411 Laurens Rd, Greenville, SC 29607

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    Premier Greenville Office Complex
    $19 SF/Yr
    1,422 SF
    Premier Greenville Office Complex

    Variety of office spaces with extensive upgrades and easy access.

    37 Villa Rd, Greenville, SC 29615

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    Flexible Open-Layout Office Suite
    $1,650/Mo
    1,200 SF
    Flexible Open-Layout Office Suite

    Open-plan office with modern finishes and on-site parking, with water, trash, and NNN costs included.

    106-2514 River Rd, Piedmont, SC 29673

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    Office Warehouse Space For Lease
    $12 SF/Yr
    5,048 SF
    Office Warehouse Space For Lease

    Office warehouse space for lease in Greenville, SC.

    180 Commerce Center, Greenville, SC 29615

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    Retail Space Next to Fitness
    $17 SF/Yr
    14,384 SF
    Retail Space Next to Fitness

    Retail space available next to Crunch Fitness on W Butler Road.

    207 West Butler Road, Mauldin, SC 29662

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    Conditioned Industrial Building in Greer
    $16 SF/Yr
    10,000 SF
    Conditioned Industrial Building in Greer

    10,000 SF fully conditioned industrial building with office space.

    19 Concourse Way, Greer, SC 29650

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    Downtown Greenville Retail Space Available
    $30 SF/Yr
    3,370 SF
    Downtown Greenville Retail Space Available

    Retail space for lease in downtown Greenville, South Carolina.

    942 S Main Street, Greenville, SC 29601

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    Main Street Professional Office Spaces
    $550/Mo
    900 SF
    Main Street Professional Office Spaces

    Newly renovated office spaces with Main Street views for lease.

    200 North Main Street, Greenville, SC 29601

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    Class A Office Space
    $45 SF/Yr
    5,024 SF
    Class A Office Space

    Premier office space in Greenville's award-winning downtown.

    110 East Court Street, Greenville, SC 29601

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    Textile Mill Lofts in Greenville
    $20 SF/Yr
    2,035 SF
    Textile Mill Lofts in Greenville

    Live, work, and play spaces with industrial architecture.

    201 Smythe Street, Greenville, SC 29611

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    Downtown Greenville Office Space
    $22 SF/Yr
    10,308 SF
    Downtown Greenville Office Space

    Turnkey office space with high-end finishes and Main Street views.

    22 S Main St, Greenville, SC 29601

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    Greenville County, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Greenville County, SC with 563 listings featured on our commercial real estate exchange. The current inventory includes 6,012,114 square feet of properties with an estimated lease value of $8,255,015.

    Estimated lease rates for Commercial real estate in Greenville County, SC begin at $0.88 SF/Yr, with an average of $34,111 and extend to $8,250,000.
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