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    Florence County, SC Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    45 results
    Adaptable Office Space in Florence
    $4,200 /Mo
    3,600 SF

    Adaptable Office Space in Florence

    720 S Coit St, Florence, SC 29501

    Well-located office building for lease in a desirable professional location.

    • Prime location directly across from Timrod Park and minutes from downtown Florence.
    • Functional layout with multiple private offices, meeting room, and reception area.
    • Ample on‑site parking for employees and visitors.
    • Classic architectural character, hardwood floors, and abundant natural light.
    • Full kitchen and basement storage.
    Updated: Apr 1
    View details
    Charming Historic Office Building Rental
    $4,200 /Mo
    3,000 SF

    Charming Historic Office Building Rental

    720 S Coit St., Florence, SC 29501

    Office building for rent across from Timrod Park.

    • Serene location directly across from Timrod Park
    • Ample parking for tenants and guests
    • Historic building with character
    • Five oversized offices
    • Includes a reception area and conference room
    Updated: Mar 26
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    Versatile Commercial Space in Florence
    $5,000 /Mo
    11,390 SF

    Versatile Commercial Space in Florence

    Commercial property with bay doors, ideal for automotive or warehouse.

    374 Darlington St., Florence, SC 29501
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    Restaurant Space Near I-95
    $7,680 /Mo
    4,190 SF

    Restaurant Space Near I-95

    Restaurant space for lease with high visibility and traffic.

    3751 W Palmetto St, Florence, SC 29501
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    Restaurant Space Near I-95
    $7,680 /Mo
    4,190 SF

    Restaurant Space Near I-95

    Restaurant space for lease with high visibility and traffic.

    3751 W Palmetto St., Florence, SC 29501
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    Retail Spaces in CrossRoads Center
    $18,134 /Mo
    95,840 SF

    Retail Spaces in CrossRoads Center

    Retail spaces available in high-traffic Florence commercial corridor.

    2522, 2524, 2528 David H McLeod Blvd, Florence, SC 29501
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    146,270 SF Industrial Warehouse
    Contact for pricing
    146,270 SF

    146,270 SF Industrial Warehouse

    Industrial warehouse with versatile use options and strategic prime location.

    729 White Oak Dr, Johnsonville, SC 29555
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    Retail Space in Florence, SC
    Contact for pricing

    Retail Space in Florence, SC

    Located at a busy intersection with high visibility and access.

    Florence, SC 29501
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    Commercial Land for Ground Lease
    Contact for pricing

    Commercial Land for Ground Lease

    2.38 acres available for ground lease in Florence, SC.

    3821 Bancroft Rd, Florence, SC 29501
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    Retail Space in Regional Destination
    $22 SF/Yr
    2,800 SF

    Retail Space in Regional Destination

    Retail space available in premier shopping center, built in 2015.

    112-120 Woody Jones Blvd, Florence, SC
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    Industrial Warehouse with Rail Access
    Contact for pricing
    146,270 SF

    Industrial Warehouse with Rail Access

    146,270 sq ft warehouse for lease near rail line.

    729 White Oak Dr, Johnsonville, SC 29555
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    Retail Space in Lake City
    $12 SF/Yr
    1,200 SF

    Retail Space in Lake City

    Retail spaces available in a busy Lake City shopping center.

    252 Kelley St, Lake City, SC
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    Commercial Office Space For Rent
    $1,950 /Mo
    2,000 SF

    Commercial Office Space For Rent

    Office space available in Shoppes at Celebration shopping center.

    2527 S Cashua Dr, Florence, SC 29501
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    Industrial Building Near I-95
    Contact for pricing
    30,000 SF

    Industrial Building Near I-95

    30,000 SF industrial space for lease near I-95.

    Enterprise Drive, Florence, SC 29501
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    Lake City Retail/Office Building
    $10 SF/Yr
    11,000 SF

    Lake City Retail/Office Building

    Retail/office building in Lake City available through 1/31/2032.

    231 Kelley St, Lake City, SC
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    Prime Land for Lease
    Contact for pricing

    Prime Land for Lease

    Strategically located land parcel with high visibility and access.

    3335 Sneed Rd, Florence, SC
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    Retail Space in Regional Destination
    $25 SF/Yr
    2,400 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination, built in 2015.

    104 Woody Jones Blvd, Florence, SC
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    Retail Space in Florence, SC
    Contact for pricing
    8,000 SF

    Retail Space in Florence, SC

    8,000 SF retail space available for lease.

    2600 David H Mcleod Blvd, Florence, SC
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    Florence Warehouse in West End
    Contact for pricing
    36,360 SF

    Florence Warehouse in West End

    Warehouse in Florence's West End District, near major retailers.

    2295 Hoffmeyer Rd, Florence, SC 29501
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    Industrial Warehouse in Florence, SC
    $4 SF/Yr
    400,000 SF

    Industrial Warehouse in Florence, SC

    400,000 SF industrial warehouse with expansion potential.

    901 N Douglas St, Florence, SC 29501
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    Renovated Retail Space on US-52
    Contact for pricing
    22,800 SF

    Renovated Retail Space on US-52

    Anchor suite in renovated shopping center with high visibility.

    1611 S Irby St, Florence, SC 29505
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    Retail Space in Regional Destination
    $22 SF/Yr
    4,475 SF

    Retail Space in Regional Destination

    Retail spaces available in premier shopping destination near major highways.

    110 Woody Jones Blvd, Florence, SC
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    Downtown Florence Open Concept Office
    Contact for pricing

    Downtown Florence Open Concept Office

    Open concept office space with exceptional visibility in Downtown Florence.

    620 W Evans St, Florence, SC 29501
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    Office Space Across From Park
    Contact for pricing

    Office Space Across From Park

    Flexible office spaces for rent in historic building.

    720 S Coit St., Florence, SC 29501
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    Florence County, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Florence County, SC with 45 listings featured on our commercial real estate exchange. The current inventory includes 1,314,205,200 square feet of properties with an estimated lease value of $94 SF/Yr.

    Estimated lease rates for Commercial real estate in Florence County, SC begin at $5 SF/Yr, with an average of $15 SF/Yr and extend to $22 SF/Yr.
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