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    Anderson County, SC Commercial Real Estate for Lease

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    75 properties
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    Adaptable Commercial Space in Anderson
    Updated: Apr 14
    Adaptable Commercial Space in Anderson

    200 W Benson Street, Anderson, SC 29624

    $7,500/Mo
    12,545 sqft
    Prime commercial property in Anderson's historic district.
    Substantial 12,545 sq ft of adaptable space.
    Generous 0.4‑acre lot with potential for expansion.
    Prominent address on Benson Street ensures excellent visibility and accessibility.
    Architectural character harmonizes with the district's charm.
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    Historic Retail Space with Courtyard Access
    Updated: Feb 17
    Historic Retail Space with Courtyard Access

    104 Exchange Street, Pendleton, SC 29670

    $3,500/Mo
    1,550 sqft
    Located on the charming Pendleton Town Square, near Clemson University.
    Historic 1910 building, formerly the Pendleton Bank, undergoing complete renovation.
    Approximately 1,550 sq ft of space including an extended annex.
    Historic renovation to restore authenticity while incorporating modern standards.
    Opportunity to take advantage of historic tax credits for upfit with early commitment.
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    First-Floor Medical/Professional Suite
    First-Floor Medical/Professional Suite

    2315 N Main Street, Anderson, SC 29621

    $500/Mo

    First-floor private office suite with shared kitchenette and conference room in a two-story brick building.

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    Office Suite with High-End Finishes
    Office Suite with High-End Finishes

    1801 North Main Street, Anderson, SC 29621

    $18 SF/Yr
    1,800 sqft

    Well-finished office suite with private offices, conference space, ample parking, and strong visibility for professional teams.

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    First-Floor Office Suite with Conference
    First-Floor Office Suite with Conference

    2315 N Main Street, Anderson, SC 29621

    $650/Mo

    First-floor private suite in a two-story, all-brick Class A office building with shared kitchenette and conference room.

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    Belton Commercial Space For Rent
    Belton Commercial Space For Rent

    121 N Main Street, Belton, SC 29627

    $1,500/Mo

    Prime commercial space in downtown Belton, South Carolina.

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    Professional Office Suite
    Professional Office Suite

    1924 McConnell Springs Road, Anderson, SC 29621

    $2,049/Mo

    Office suite includes three offices, a kitchenette, and a dedicated restroom within a professional office building.

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    Endcap Retail or Office Space
    Endcap Retail or Office Space

    1638 North Main Street, Anderson, SC 29621

    $11 SF/Yr
    2,696 sqft

    Endcap space with strong daily traffic, signalized access, and 47 parking spaces for retail or office users.

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    First-Floor Class A Office Suite
    First-Floor Class A Office Suite

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    First-floor office suite in a two-story all-brick Class A building with on-site utilities and maintenance included.

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    First-Floor Office Suite
    First-Floor Office Suite

    2315 N Main Street, Anderson, SC 29621

    $3,400/Mo

    First-floor suite with 8 private offices, kitchen, and conference room in a Class A, all-brick building.

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    Miracle Mile Commercial Building
    Miracle Mile Commercial Building

    102 Miracle Mile Dr, Anderson, SC 29621

    $10.50 SF/Yr
    4,000 sqft

    Approximately 4000 SF building for lease with high visibility.

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    Corner Storefront with Shell Space
    Corner Storefront with Shell Space

    102 Exchange Street, Pendleton, SC 29670

    $3,100/Mo

    Historic, restored building offers a shell space for a tenant to shape a flexible street-level concept.

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    Renovated Retail Space Available
    Renovated Retail Space Available

    1012 E Shockley Ferry Rd, Anderson, SC 29624

    $1,500/Mo
    1,800 sqft

    Renovated retail building with frontage and open space.

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    Renovated Office Building For Rent
    Renovated Office Building For Rent

    1311 South Murray Avenue, Anderson, SC 29624

    $1,300/Mo
    1,300 sqft

    Renovated office building with versatile space for rent.

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    Office Space Near Downtown Anderson
    Office Space Near Downtown Anderson

    1214 North Main Street, Anderson, SC 29621

    $1,200/Mo
    900 sqft

    Office suite with three private offices, reception, and kitchenette.

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    Flex Building with Office, Warehouse
    Flex Building with Office, Warehouse

    109 Old Denver Road, Anderson, SC 29625

    $4,000/Mo
    3,200 sqft

    Flex building with office and warehouse space for lease.

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    New Warehouse Space Available
    New Warehouse Space Available

    730 Hampton Road, Williamston, SC 29697

    $8.50 SF/Yr
    30,000 sqft

    New warehouse space for lease, convenient I-85 access.

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    New Warehouse Space in Anderson
    New Warehouse Space in Anderson

    00 Vanguard Rd, Anderson, SC 29625

    $8.50 SF/Yr
    50,000 sqft

    New warehouse space for lease near I-85, Exit 19.

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    Modern Office Space Available
    Modern Office Space Available

    521 N Mcduffie St, Anderson, SC 29621

    $500/Mo

    Updated office space with 9 offices, conference room, and breakroom.

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    Corner Retail Site For Lease
    Corner Retail Site For Lease

    1499 Pearman Dairy Rd, Anderson, SC 29625

    $19 SF/Yr
    3,500 sqft

    High-visibility corner retail site available for lease or redevelopment.

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    Former Sears Box in Mall
    Former Sears Box in Mall

    3101 N Main St, Anderson, SC 29621

    Contact for pricing
    90,750 sqft

    90,750 SF retail space in Anderson Mall available for lease.

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    Multi-Building Industrial Campus
    Multi-Building Industrial Campus

    245 WELPINE RD, Pendleton, SC 29670

    Contact for pricing
    19,550 sqft

    Industrial campus with front office and reception, multiple warehouses, and two ingress/egress for practical contractor use.

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    Belton Retail/Office Suites Available
    Belton Retail/Office Suites Available

    729 Anderson Street, Belton, SC 29627

    $8 SF/Yr

    Multi-tenant strip center with retail/office suites for lease.

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    Downtown Anderson Retail Space Available
    Downtown Anderson Retail Space Available

    151 E Church St, Anderson, SC 29624

    $5,000/Mo

    Retail space available for lease in downtown Anderson, SC.

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    Anderson County, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Anderson County, SC with 75 listings featured on our commercial real estate exchange. The current inventory includes 581,775 square feet of properties with an estimated lease value of $245.22 SF/Yr.

    Estimated lease rates for Commercial real estate in Anderson County, SC begin at $4.50 SF/Yr, with an average of $12.26 SF/Yr and extend to $27.10 SF/Yr.
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