Spartanburg, SC
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    Spartanburg, SC Commercial Real Estate for Lease

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    Boiling Springs, SC Roebuck, SC Wellford, SC
    159 results
    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF
    Premier Medical Office Space Available

    1650 Skylyn Drive, Spartanburg, SC 29307

    Class A medical office space in Spartanburg's prime location.
    • Premier Class A medical office space, strategically located on the Mary Black campus, unique to the Spartanburg market.
    • On‑site wellness amenity suite featuring a fitness gym, swimming pool, and smoothie bar exclusively for building tenants.
    • Lower NNN fees than comparable properties.
    • Direct access to the Drayton Mills Trail and proximity to the vibrant Drayton Mills mixed‑use development.
    • Abundant parking.
    Updated: Mar 7
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    Restaurant Space in Drayton Mills
    $29 SF/Yr
    6,979 SF
    Restaurant Space in Drayton Mills

    1802 Drayton Road Suite I, Spartanburg, SC 29307

    Second-generation restaurant space in a historic mixed-use development.
    • Second‑generation restaurant space significantly reduces startup costs and time to opening.
    • Located at the entrance to the vibrant Drayton Mills mixed‑use development.
    • ±6,979 SF space within a fully restored historic mill environment.
    • High ceilings, exposed brick, large windows, and authentic mill character.
    • Located within Drayton Mills live‑work campus with 500+ residents and consistent daily foot traffic.
    Updated: Mar 5
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    Spartanburg Automotive Shop For Lease
    $11 SF/Yr
    2,000 SF
    Spartanburg Automotive Shop For Lease

    2,000 SF automotive shop or light industrial space available.

    51A Dexter Rd, Spartanburg, SC 29303

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    Spartanburg Storefront Retail/Office Space
    $15 SF/Yr
    2,046 SF
    Spartanburg Storefront Retail/Office Space

    Renovated 2,046 SF retail/office space in downtown Spartanburg.

    512 E Main St, Spartanburg, SC 29302

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    6,000 SF Flex Building I-85
    Contact for pricing
    6,000 SF
    6,000 SF Flex Building I-85

    Flex building with lay-down yard fronting I-85.

    50 Fairview Church Rd, Spartanburg, SC 29303

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    Move-in Ready Furnished Office Space
    $20 SF/Yr
    Move-in Ready Furnished Office Space

    Recently renovated, fully furnished office building in a prime location.

    792 John B White Sr Boulevard, Spartanburg, SC 29306

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    Spartanburg Retail Suites For Lease
    Contact for pricing
    74,481 SF
    Spartanburg Retail Suites For Lease

    Retail suites available in a high-traffic Spartanburg shopping center.

    2199 Southport Road, Spartanburg, SC 29302

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    Historic Mill Office Space Available
    $28 SF/Yr
    53,571 SF
    Historic Mill Office Space Available

    Creative office space in a vibrant mixed-use community.

    1802 Drayton Road, Suite 140B, Spartanburg, SC 29307

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    Premier Office Suite For Rent
    $700/Mo
    425 SF
    Premier Office Suite For Rent

    Executive office suite in a premier location with ample natural light.

    1451 E Main St, Spartanburg, SC

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    Spartanburg Outdoor Storage Opportunity
    $4,000/Mo
    Spartanburg Outdoor Storage Opportunity

    4.38 AC outdoor storage lot for lease in Spartanburg.

    220 West Lanford Street |, Spartanburg, SC 29302

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    Retail Space with Highway Access
    $22 SF/Yr
    4,500 SF
    Retail Space with Highway Access

    4,500 SF retail space with flexible terms and visibility.

    2799 Reidville Rd, Spartanburg, SC

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    Spartanburg Office Space Available
    $25 SF/Yr
    444 SF
    Spartanburg Office Space Available

    Office space available for rent in Spartanburg, South Carolina.

    324 E Saint John St, Spartanburg, SC

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    Renovated Office Space Available
    $20 SF/Yr
    1,500 SF
    Renovated Office Space Available

    Newly renovated office space in a high-visibility location.

    901 S Pine St, Spartanburg, SC

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    Retail Space in Westgate Mall
    $12 SF/Yr
    1,837 SF
    Retail Space in Westgate Mall

    Retail space available for lease in Westgate Mall.

    210-220 Westgate Mall Dr, Spartanburg, SC

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    Retail Space For Rent
    $16 SF/Yr
    1,400 SF
    Retail Space For Rent

    Retail space available for lease in Spartanburg, South Carolina.

    200 Dawn Redwood Dr, Spartanburg, SC

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    Industrial Space in Spartanburg
    Contact for pricing
    140,400 SF
    Industrial Space in Spartanburg

    140,400 SF industrial space available for lease.

    171 International Park Dr, Spartanburg, SC 29301

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    Westside Office Building For Rent
    $12 SF/Yr
    5,000 SF
    Westside Office Building For Rent

    5,000 sq ft office building in westside location.

    1220 John B White Sr Blvd, Spartanburg, SC

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    Spartanburg Warehouse with Outdoor Storage
    $8 SF/Yr
    21,000 SF
    Spartanburg Warehouse with Outdoor Storage

    Warehouse/distribution space with office, showroom, and outdoor storage available for lease.

    2075 Chesnee Highway |, Spartanburg, SC 29303

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    Spartanburg Warehouse/Flex Space Available
    $8 SF/Yr
    15,000 SF
    Spartanburg Warehouse/Flex Space Available

    15,000 SF warehouse/flex space with showroom/office in Spartanburg, SC.

    511 Bryant Rd, Spartanburg, SC

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    Downtown Spartanburg Retail/Office Space
    $23 SF/Yr
    1,525 SF
    Downtown Spartanburg Retail/Office Space

    Retail or office space with high visibility in downtown.

    178-182 E Main St, Spartanburg, SC

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    Spartanburg Office Space for Lease
    $16 SF/Yr
    1,200 SF
    Spartanburg Office Space for Lease

    Office space available near downtown Spartanburg with on-site parking.

    301 N Pine St, Spartanburg, SC

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    Spartanburg Flexible Space For Rent
    $8 SF/Yr
    34,053 SF
    Spartanburg Flexible Space For Rent

    Flexible space suitable for retail or mixed-use purposes.

    1201 Union, Spartanburg, SC

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    Spartanburg Flex Building For Lease
    Contact for pricing
    6,800 SF
    Spartanburg Flex Building For Lease

    Flex building with office and outdoor storage in Spartanburg.

    440 Southport Commerce Blvd, Spartanburg, SC 29306

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    Downtown Spartanburg Office Space
    $16 SF/Yr
    1,395 SF
    Downtown Spartanburg Office Space

    Office space in downtown Spartanburg with professional finishes.

    275 E Henry St, Spartanburg, SC

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    Spartanburg, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Spartanburg, SC with 159 listings featured on our commercial real estate exchange. The current inventory includes 1,066,620 square feet of properties with an estimated lease value of $13,145 /Mo.

    Estimated lease rates for Commercial real estate in Spartanburg, SC begin at $4 SF/Yr, with an average of $177 SF/Yr and extend to $12,000 /Mo.
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