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    Lexington County, SC Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    575 results
    SC, Columbia - 1501 Main St
    Contact for pricing

    SC, Columbia - 1501 Main St

    Discover many ways to work your way in SC, Columbia - 1501 Main St

    1501 Main St, Unit 501, Columbia, SC 29201
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    Main Street
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    Main Street

    Discover many ways to work your way in Main Street

    1320 Main St, Unit 300, Columbia, SC 29201
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    Freestanding Retail Building For Lease
    $14 SF/Yr
    5,000 SF

    Freestanding Retail Building For Lease

    422 Bush River Road, Columbia, SC 29210

    Freestanding retail building in high-traffic area near Dutch Square Mall.

    • Highly visible, freestanding building on a corner lot in a busy retail corridor.
    • Located directly adjacent to Dutch Square Mall.
    • High traffic counts: 22,700 VPD (Bush River Rd.) and 7,300 VPD (Colonial Life Blvd.).
    • Located in the Bush/Broad River Road retail corridor with many surrounding retailers.
    • Ample on‑site parking (3 per 1,000 RSF).
    Updated: Mar 6
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    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF

    Reimagined Class-A Office Space

    1710 Gervais St., Columbia, SC 29201

    Newly renovated office space in prime downtown location.

    • Prime Gervais Street location, walk to Capitol, Main Street, restaurants, coffee shops, and downtown amenities.
    • Newly reimagined Class‑A office space blending iconic 1969 architecture with modern finishes.
    • Complete interior gut and rebuild underway, creating a sleek, modern, and highly functional workspace with high‑end finishes.
    • Thoughtfully designed for modern office use with open collaboration areas, private offices, conference rooms, and flexible layouts for hybrid work.
    • ±7,521 SF available on the first floor (entire floor) & ±4,000 SF available on the 2nd floor.
    Updated: Mar 6
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    Retail Space on High-Traffic Corridor
    $25 SF/Yr
    3,591 SF

    Retail Space on High-Traffic Corridor

    3,500 SF retail space on Taylor St, ample parking.

    1531 Taylor St, Columbia, SC 29201
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    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    Two-story office building with flexible layout in central Columbia.

    123 Lawand Dr, Columbia, SC 29210
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    Former Restaurant on Decker Boulevard
    $22 SF/Yr
    4,320 SF

    Former Restaurant on Decker Boulevard

    4,320 SF former restaurant with drive-thru on 1.13 AC.

    2600 Decker Boulevard, Columbia, SC 29206
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    Office Space in Vista District
    $23 SF/Yr
    6,782 SF

    Office Space in Vista District

    Office spaces for lease in Columbia's popular Vista district.

    500 Taylor Street, Columbia, SC 29201
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    Mixed-Use Property in Cayce, SC
    $825 /Mo
    7,541 SF

    Mixed-Use Property in Cayce, SC

    Mixed-use property suitable for redevelopment, retail, or office use.

    528-532 Knox Abbott Dr, Cayce, SC 29033
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    West Columbia Office/Medical Suite
    $18 SF/Yr
    12,000 SF

    West Columbia Office/Medical Suite

    Office/medical suite for lease near Lexington Medical Hospital.

    3618 Sunset Blvd., West Columbia, SC 29169
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    Office Space For Rent
    $20 SF/Yr
    15,000 SF

    Office Space For Rent

    Office suites available in Columbia, between Downtown and Forest Acres.

    3321 Forest Drive, Columbia, SC 29204
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    Historic Arcade Mall Retail Space
    $600 /Mo
    39,320 SF

    Historic Arcade Mall Retail Space

    Historic indoor shopping center with high-end finishes in downtown Columbia.

    1332 Main St, Columbia, SC 29201
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    SC, Columbia - Stoneridge Drive
    Contact for pricing

    SC, Columbia - Stoneridge Drive

    Workspaces, services and support to help you work better in SC, Columbia - Stoneridge Drive

    140 Columbia Ave, Columbia, SC 29210
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    New Lexington County Office Space
    $23 SF/Yr
    6,500 SF

    New Lexington County Office Space

    Office space for lease in a growing Lexington County location.

    120 Brookside Parkway, Lexington, SC 29072
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    Office Suite in West Columbia
    $15 SF/Yr
    9,890 SF

    Office Suite in West Columbia

    Office suite for lease near downtown Columbia and Lexington Medical Center.

    1523 Sunset Blvd., West Columbia, SC 29169
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    Freestanding Building in West Columbia
    $18 SF/Yr
    10,000 SF

    Freestanding Building in West Columbia

    10,125 SF freestanding building on a busy retail corridor.

    1210 Charleston Hwy., West Columbia, SC 29169
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Circle, West Columbia, SC 29169
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    Flex Space Near Interstate I-26
    $15 SF/Yr
    2,520 SF

    Flex Space Near Interstate I-26

    Professional flex and light manufacturing space with easy interstate access.

    104 Corporate Boulevard, West Columbia, SC 29169
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    Prime Office Space on Devine
    $23 SF/Yr
    12,200 SF

    Prime Office Space on Devine

    Office space for lease in the Devine Street District.

    2422 Devine Street, Columbia, SC 29205
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    Warehouse with Secured Yard
    $12 SF/Yr
    5,000 SF

    Warehouse with Secured Yard

    5,000 SF warehouse with office and secured yard.

    125 North Shorecrest Drive, Columbia, SC 29209
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    Renovated Vista Office Space
    $21 SF/Yr
    7,280 SF

    Renovated Vista Office Space

    Office space in The Vista near State House and USC.

    720 Lady Street, Columbia, SC 29201
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    Devine Street Office Space Available
    $18 SF/Yr
    10,500 SF

    Devine Street Office Space Available

    Office space for lease on highly trafficked Devine Street.

    2442 Devine St., Columbia, SC 29205
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    Columbia Office Space For Lease
    $17 SF/Yr
    7,072 SF

    Columbia Office Space For Lease

    High-quality office space in a well-located Columbia area.

    8910 Two Notch Road, Columbia, SC 29223
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    Downtown Columbia Office Space Available
    $17 SF/Yr
    8,584 SF

    Downtown Columbia Office Space Available

    Office spaces for lease in downtown Columbia, South Carolina.

    1901 Gadsden Street, Columbia, SC 29201
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    Lexington County, SC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lexington County, SC with 575 listings featured on our commercial real estate exchange. The current inventory includes 18,562,222,800 square feet of properties with an estimated lease value of $894 /Mo.

    Estimated lease rates for Commercial real estate in Lexington County, SC begin at $5 SF/Yr, with an average of $17 SF/Yr and extend to $40 SF/Yr.
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