Lexington County, SC Commercial real estate for Rent & Lease

SC, Columbia - Williams Street

1600 Williams St, Unit 2ND, Columbia, SC 29201

$129-$14,042/Mo

11-2,239 sqft

(972) 764-8885

Discover many ways to work your way in SC, Columbia - Williams Street

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Main Street

1320 Main St, Unit 300, Columbia, SC 29201

$129-$21,593/Mo

11-2,088 sqft

(972) 764-8885

Flexible workspace in Main Street. Book a tour & get info

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Updated: Jun 25

Fully Conditioned Flex Suite

4611 Broad River Road, Suite C, Columbia, SC 29210

$2,400/Mo

1,750 sqft

1,750 SF fully conditioned retail/flex space for lease on Broad River Road in Columbia
Includes private office and restroom
One 10' x 10' roll‑up door
10 ft ceilings
Ample on‑site parking

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Updated: Jun 18

Newly Renovated Office Building

1034 Briargate Circle, Columbia, SC 29210

$1,300/Mo

2,328 sqft

Freshly renovated two‑story office building in St. Andrews submarket
Available suite offers multiple offices plus conference room, storage, and reception area (1,156 SF)
Suite is expandable up to 2,328 SF
On‑site parking for 22 vehicles (4.76 parking ratio)
Close proximity to I‑20 and about 10 minutes to Downtown Columbia

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Turnkey Medical Office Suites

4100 N. Main Street, Columbia, SC 29203

$20 SF/Yr

3,742 sqft

Turnkey suites with exam rooms and plumbing, recently renovated common areas, designed for efficient medical operations.

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Freestanding Flex Building

175 Foster Brothers Dr # 179, West Columbia, SC 29172

$11 SF/Yr

6,000 sqft

Freestanding flex building with office, warehouse space, dock and drive-in doors, and room for yard storage or parking.

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Move-In Ready Office Suite

1927 Thurmond Mall, Columbia, SC 29201

$22.50 SF/Yr

6,339 sqft

Class A office space with seven private offices, conference rooms, collaboration areas, and free surface parking.

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SC, Columbia - 1501 Main St

1501 Main St, Unit 501, Columbia, SC 29201

$129-$17,909/Mo

11-2,011 sqft

Flexible workspace in SC, Columbia - 1501 Main St. Book a tour & get info

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Medical Office Complex For Rent

2601 Laurel St, Columbia, SC

$28 SF/Yr

1,797 sqft

Medical office complex in Columbia's Central Business District.

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Industrial Warehouse with Dock and Drive-In

7224 Middle Street, Columbia, SC 29223

$5,500/Mo

8,000 sqft

Functional warehouse with 14-foot ceilings, dock high and drive-in doors, and office space for distribution or light manufacturing.

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Two-Story Office Building For Rent

123 Lawand Dr, Columbia, SC 29210

$16.92 SF/Yr

3,960 sqft

Two-story office building with flexible layout in central Columbia.

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Mixed-Use Property in Cayce, SC

528-532 Knox Abbott Dr, Cayce, SC 29033

$825/Mo

7,541 sqft

Mixed-use property suitable for redevelopment, retail, or office use.

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Office Space in Vista District

500 Taylor Street, Columbia, SC 29201

$23.25 SF/Yr

6,782 sqft

Office spaces for lease in Columbia's popular Vista district.

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Industrial Flex Building with Storage

2519 Wessinger Rd, Chapin, SC 29036

$12 SF/Yr

10,500 sqft

Flexible industrial space with clear-span warehouse interiors and large paved outdoor storage.

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Retail/Office Space in Forest Acres

3304-3312 Forest Drive, Columbia, SC 29204

$19 SF/Yr

1,464 sqft

Retail/office space in a visible, accessible, and affordable location.

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Medical Office Complex For Rent

2750 Laurel St., 2601 Laurel St. & 1655 Bernardin Ave., Columbia, SC 29206

$28 SF/Yr

126,002 sqft

Medical office complex in Columbia's Central Business District, renovated.

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Premier Office Tower with Capitol Views

1221 Main Street, Columbia, SC 29201

$40 SF/Yr

2,289 sqft

Office space in Columbia's premier tower with integrated parking.

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Flex Space Near Interstate I-26

104 Corporate Boulevard, West Columbia, SC 29169

$15.75 SF/Yr

2,520 sqft

Professional flex and light manufacturing space with easy interstate access.

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Forest Acres Office Space Available

4875 Forest Dr, Columbia, SC

$25 SF/Yr

1,590 sqft

Office space in a sought-after location with monument signage.

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Columbia Flex Space For Lease

901 Brookwood Drive, Columbia, SC 29201

$12 SF/Yr

12,550 sqft

Flex space available for lease in Columbia, South Carolina.

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West Columbia Office/Medical Suite

3618 Sunset Blvd., West Columbia, SC 29169

$18 SF/Yr

12,000 sqft

Office/medical suite for lease near Lexington Medical Hospital.

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Historic Arcade Mall Retail Space

1332 Main St, Columbia, SC 29201

$600/Mo

39,320 sqft

Historic indoor shopping center with high-end finishes in downtown Columbia.

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Medical Office Space For Lease

161 Medical Circle, West Columbia, SC 29169

$20 SF/Yr

7,659 sqft

Medical office space in prime healthcare corridor location.

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Office Suite in West Columbia

1523 Sunset Blvd., West Columbia, SC 29169

$15 SF/Yr

9,890 sqft

Office suite for lease near downtown Columbia and Lexington Medical Center.

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Downtown Columbia Office Space Available

1333 Main Street, Columbia, SC 29201

$21.75 SF/Yr

17,594 sqft

Prime office space for rent in downtown Columbia.

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Columbia Office Building For Lease

1628 Browning Road, Columbia, SC 29210

$15.75 SF/Yr

16,966 sqft

Class B office space with interstate visibility and modern amenities.

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Lexington County, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Lexington County, SC with 465 listings featured on our commercial real estate exchange. The current inventory includes 3,493,542 square feet of properties with an estimated lease value of $4,666 /Mo.

Estimated lease rates for Commercial real estate in Lexington County, SC begin at $1.31 SF/Yr, with an average of $18.52 SF/Yr and extend to $140.73 SF/Yr.