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    South Carolina Office Spaces for Lease

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    Greenville, SC Columbia, SC Charleston, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Myrtle Beach, SC Summerville, SC
    992 properties
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    Renovated Office Building For Lease
    Renovated Office Building For Lease

    506 Pettigru St, Greenville, SC 29601

    $26.25 SF/Yr
    3,696 sqft

    Renovated office building with suite available near downtown Greenville.

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    Office Space in First Citizens
    Office Space in First Citizens

    1230 Main St, Columbia, SC 29201

    $30 SF/Yr
    3,345 sqft

    3,345 SF office space available for rent.

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    Office Space in Forest Acres
    Office Space in Forest Acres

    4408 Forest Dr, Columbia, SC 29206

    $18 SF/Yr

    Office space for lease in a central Forest Acres location.

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    Columbia Industrial Flex Space Available
    Columbia Industrial Flex Space Available

    6011 Shakespeare Rd, Columbia, SC 29223

    Contact for pricing
    59,789 sqft

    Industrial flex buildings with office, warehouse, and storage spaces.

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    Downtown Columbia Office Space Available
    Downtown Columbia Office Space Available

    1501 Main St, Columbia, SC 29201

    $18 SF/Yr

    Office space for rent in downtown Columbia, South Carolina.

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    Office Space in Carolina Research
    Office Space in Carolina Research

    7 Technology Cir, Columbia, SC 29203

    $20.50 SF/Yr

    Office space in a campus-like setting with corporate neighbors.

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    Two-Story Office Building
    Two-Story Office Building

    213 Surfside Dr, Surfside Beach, SC 29575

    $108 SF/Yr
    2,100 sqft

    Two-story office layout with 12 on-site parking spaces and HVAC installed in 2017.

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    Commercial Land For Ground Lease
    Commercial Land For Ground Lease

    Sigma Drive, Summerville, SC 29486

    Contact for pricing

    Approximately 1.0 acre of commercial land available for lease.

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    Marion SC Commercial Space Available
    Marion SC Commercial Space Available

    1450 E Northside Avenue, Marion, SC 29571

    Contact for pricing

    Commercial space featuring reception, offices, conference, and break rooms.

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    Multi-Tenant Office Building in Columbia
    Multi-Tenant Office Building in Columbia

    1600 Williams St, Columbia, SC 29201

    $19.75 SF/Yr
    41,519 sqft

    140,206 SF office building with suites available for rent.

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    Mixed-Use Development on Highway 41
    Mixed-Use Development on Highway 41

    1031 & 1039 Hwy 41, Mount Pleasant, SC 29466

    $28 SF/Yr
    16,000 sqft

    Multi-building mixed-use development with retail and office space.

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    Rock Hill Retail/Restaurant/Office Space
    Rock Hill Retail/Restaurant/Office Space

    2670 Mills Park Dr, Rock Hill, SC 29732

    Contact for pricing
    23,000 sqft

    Affluent Rock Hill corridor, available June 2025, lease option.

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    Columbia Flex/Industrial/Office Space Available
    Columbia Flex/Industrial/Office Space Available

    2711 Alpine Rd, Columbia, SC 29223

    $10 SF/Yr

    Flex, industrial, and office spaces for lease in Columbia.

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    Office Suite for Staffing Agency
    Office Suite for Staffing Agency

    21 Orchard Park Dr, Greenville, SC 29615

    $20 SF/Yr

    Existing staffing agency office suite available for occupancy starting June 1, 2026.

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    Prestigious Office Suites in Florence
    Prestigious Office Suites in Florence

    1831 W Evans St, Florence, SC 29501

    $25 SF/Yr
    4,453 sqft

    Corporate office suites available for lease in Florence, SC.

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    Class A Office Building Suites
    Class A Office Building Suites

    1016 2nd Ave N, North Myrtle Beach, SC 29582

    $16 SF/Yr
    36,000 sqft

    Three-story office building with modern interior and executive suites.

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    Edgewater Medical/Office Building III
    Edgewater Medical/Office Building III

    Edgewater Pkwy, Indian Land, SC 29707

    Contact for pricing
    15,000 sqft

    Medical and office spaces available for lease in Indian Land.

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    Mount Pleasant Office Space
    Mount Pleasant Office Space

    1671 Belle Isle Avenue, Mount Pleasant, SC 29464

    $32 SF/Yr

    Office space available for lease in Mount Pleasant, SC.

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    New Class A Medical/Office Development
    New Class A Medical/Office Development

    00 Edgewater Pkwy, Indian Land, SC 29707

    Contact for pricing
    60,000 sqft

    New Class A medical/office development in Edgewater Corporate Park.

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    New Class A Medical/Office Development
    New Class A Medical/Office Development

    Edgewater Pkwy, Indian Land, SC 29707

    Contact for pricing
    60,000 sqft

    New Class A medical/office development in Edgewater Corporate Park.

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    High Visibility Office Space Available
    High Visibility Office Space Available

    102 Commons Blvd, Powdersville, SC 29673

    $15 SF/Yr

    Office space with high traffic and signage opportunities.

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    Class A Office Space
    Class A Office Space

    40 Calhoun St, Charleston, SC 29401

    $39.23 SF/Yr

    Walkable campus with office and service-related businesses.

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    Retail, Restaurant, or Medical Office
    Retail, Restaurant, or Medical Office

    2800 Rosewood Dr, Columbia, SC 29205

    Contact for pricing

    Located in Publix-anchored shopping center with high visibility.

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    Office Suites Available For Rent
    Office Suites Available For Rent

    301 N Main St, Greenville, SC 29601

    $25 SF/Yr

    Office suites of various sizes available for rent.

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