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    Anderson, SC
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    Anderson, SC Medical Office Space for Lease

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    Belton, SC Pendleton, SC Williamston, SC
    Class A Office Space
    $3,400/Mo

    Class A Office Space

    2315 N Main Street, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Nov 13, 2025
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    East Greenville Street Office Space
    Contact for pricing
    2,000 SF

    East Greenville Street Office Space

    1403 East Greenville Street, Anderson, SC 29621

    Office or medical suite with ample parking and high visibility.

    • High‑visibility location on a heavily trafficked corridor (26,500 vehicles per day).
    • Ample free on‑site surface parking.
    • Functional layout with 5 offices, open area, admin office, and kitchen/break room.
    • Suitable for office or medical use.
    • Multiple points of ingress/egress, including access to a signalized intersection.
    Updated: Nov 22, 2025
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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 2 Active listings in Anderson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Greenville Medical Office Space
    $30 SF/Yr
    2,600 SF

    Greenville Medical Office Space

    Modern medical office space available for lease in Greenville, SC.

    3807 White Horse Rd, Greenville, SC
    View details
    Medical Office Space For Rent
    Contact for pricing
    1,336 SF

    Medical Office Space For Rent

    Newly renovated medical office space in Greenville's medical corridor.

    62 Bear Dr, Greenville, SC
    View details
    334,000 SF Office Building For Lease
    $19 SF/Yr

    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681
    View details
    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF

    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681
    View details

    Similar Spaces for Sale in Anderson, SC

    Consider Similar Space for Sale. We found 8 Spaces matching your search parameters.

    Buildable Medical Office Pad Site
    $90,000
    0.48 Acres
    Buildable Medical Office Pad Site

    Condo-style pad site in established medical park setting.

    110 Buford Avenue lot: 28B, Anderson, SC 29621

    View details
    Move-in Ready Office Space
    $189,900
    Move-in Ready Office Space

    Professional office space in excellent condition near hospital.

    400 N Fant Street, Anderson, SC 29621

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    Anderson Office Building For Sale
    $649,000
    4,550 SF
    Anderson Office Building For Sale

    Well-located office building near Clemson Boulevard and AnMed Medical Center.

    131 Straight Drive, Anderson, SC 29625

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    Commercial Lot in Mall Park
    Contact for pricing
    0.15 Acres
    Commercial Lot in Mall Park

    Centrally located commercial lot near shopping, dining, and civic center.

    29 Civic Center Boulevard, Anderson, SC 29625

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    Medical Office Building For Sale
    $1,050,000
    10,405 SF
    Medical Office Building For Sale

    Multi-tenant medical office building near AnMed campuses with development potential.

    102 Buford Avenue, Anderson, SC 29621

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    Anderson Office Building For Sale
    $649,000
    4,550 SF
    Anderson Office Building For Sale

    Well-located office building near Clemson Boulevard and AnMed Medical Center.

    133 Straight Dr, Anderson, SC 29625

    View details
    Medical Office Building with Lab
    $925,000
    4,300 SF
    Medical Office Building with Lab

    4,300 SF medical office with redevelopment potential.

    1502 E Greenville St, Anderson, SC 29621

    View details
    Prime Corner Commercial Opportunity
    $1,400,000
    3,653 SF
    Prime Corner Commercial Opportunity

    High-visibility commercial space in Anderson, SC, suitable for various businesses.

    602 N Main St, Anderson, SC 29621

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
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    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
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    Corner Lot on Highway 72
    $5,000/Mo
    1,875 SF

    Corner Lot on Highway 72

    1.7 acre corner lot zoned for commercial, medical, residential.

    30472 Highway 72, Madison, AL 35756
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details

    Anderson, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Anderson, SC with 2 listings featured on our commercial real estate exchange. The current inventory includes 0 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Medical Office Space in Anderson, SC begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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