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Greenville, SC Medical Office Space for Lease

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14 results
Medical Office Space For Lease
$26 SF/Yr
45,200 SF

Medical Office Space For Lease

10 Enterprise Blvd., Greenville, SC 29615

Medical office space near Prisma Health Patewood & Bon Secours.

  • Prime Location: One block from Prisma Health Patewood Campus & Bon Secours Francis Eastside.
  • Medical/Healthcare Focus: Ideal office space for medical or healthcare practices.
  • Flexible Lease Terms: Adaptable lease options to suit tenant needs.
  • Available Space: 1,634 - 3,297 SF available, offering options for different sized practices.
  • Renovated Common Areas: Updated and well‑maintained shared spaces.
Updated: Jan 27
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Medical Office Space For Lease
$13 SF/Yr
8,000 SF

Medical Office Space For Lease

3535 Pelham Road, Greenville, SC 29615

Medical office space for lease in Greenville, South Carolina.

  • Prime location on Pelham Road corridor in Greenville County.
  • Convenient access: Less than a mile to I‑85.
  • Medical office space suitable for various practices.
  • Flexible space: Can be divided to suit tenant needs.
  • Features 9 private offices, 2 conference rooms, lobby, and break room.
Updated: Sep 25, 2025
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Turnkey Healthcare Suite Available
Contact for pricing

Turnkey Healthcare Suite Available

Ready-to-occupy medical suite with excellent visibility and accessibility.

2709 Pelham Road, Greenville, SC 29615
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Greenville Medical Office Space
$30 SF/Yr
2,600 SF

Greenville Medical Office Space

Modern medical office space available for lease in Greenville, SC.

3807 White Horse Rd, Greenville, SC
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Medical Office Near Greenville Memorial
$18 SF/Yr
22,786 SF

Medical Office Near Greenville Memorial

Medical office space for rent near Greenville Memorial Hospital.

8 Memorial Medical Ct, Greenville, SC
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Medical Office Space For Lease
$18 SF/Yr
3,000 SF

Medical Office Space For Lease

Medical office space available for lease in Greenville, SC.

274 B Commonwealth Drive, Greenville, SC 29615
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Two-Story Office Building Available
Contact for pricing
5,500 SF

Two-Story Office Building Available

Two-story office building with ample parking and multiple access points.

501 Roper Mountain Rd, Greenville, SC
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Prime Medical Office Space
$18 SF/Yr
15,448 SF

Prime Medical Office Space

Eastside Greenville location near Prisma and Bon Secours campuses.

800 Pelham Rd, Greenville, SC
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Greenville Office/Medical Space For Rent
Contact for pricing
1,005 SF

Greenville Office/Medical Space For Rent

Office or medical space available in Greenville, SC.

20 Creekview Ct, Greenville, SC
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Medical Office Space For Rent
Contact for pricing
1,336 SF

Medical Office Space For Rent

Newly renovated medical office space in Greenville's medical corridor.

62 Bear Dr, Greenville, SC
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2,250 SF Office Building
$12 SF/Yr

2,250 SF Office Building

2,250 SF Office Building

105 Lydia St, Greenville, SC 29605
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Prime Greenville Location Retail/Medical
Contact for pricing

Prime Greenville Location Retail/Medical

Retail or medical space in high-traffic Greenville location.

75 E McBee Ave., Greenville, SC 29601
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Greenville Office Space For Rent
$23 SF/Yr
5,600 SF

Greenville Office Space For Rent

Flexible office space near Patewood Medical Campus available for rent.

127 Halton Village Cir, Greenville, SC
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Medical Office Space Near Hospital
Contact for pricing
4,232 SF

Medical Office Space Near Hospital

Stand-alone building ideal for medical use near Greenville Memorial.

1200 W Faris Rd, Greenville, SC 29605
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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 14 Active listings in Greenville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Explore Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

334,000 SF Office Building For Lease
$19 SF/Yr

334,000 SF Office Building For Lease

334,000 SF Office Building For Lease

300 South St, Simpsonville, SC 29681
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334,000 SF Office Building For Lease
$19 SF/Yr

334,000 SF Office Building For Lease

334,000 SF Office Building For Lease

300 South St, Simpsonville, SC 29681
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Turn Key Medical Office Space
$23 SF/Yr
5,000 SF

Turn Key Medical Office Space

New construction medical office space in close proximity to airport.

100 Constantine Wy, Greer, SC
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Greer Retail & Restaurant Space
Contact for pricing
2,400 SF

Greer Retail & Restaurant Space

Retail, restaurant, and medical office spaces available for lease.

2000 Hwy 101 S, Greer, SC
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Explore Similar Spaces for Sale in Greenville, SC

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

Medical Office Building For Sale
$2,395,000
7,397 SF

Medical Office Building For Sale

Two-story, ±7,397 SF medical office building suited for owner-occupant.

300 Regent Park Ct, Greenville, SC
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Freestanding Office Building For Sale
$1,700,000
6,046 SF

Freestanding Office Building For Sale

Freestanding office building in desirable Eastside office corridor.

5 Hawthorne Park Ct, Greenville, SC 29615
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Commercial Lot For Rent
$7,500/Mo

Prime Commercial Lot For Rent

0.66 acre commercial lot with high visibility.

Tift Avenue N, Tifton, GA 31794
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Highway 72 Corner Lot
$6,500/Mo
1,875 SF

Highway 72 Corner Lot

1.6 acre commercial lot for rent on Highway 72.

30472 Highway 72, Madison, AL 35756
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Valdosta Commercial Land For Lease
Contact for pricing
43,560 SF

Valdosta Commercial Land For Lease

Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
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Winter Park Mixed-Use Opportunity
$8,500/Mo
23,056 SF

Winter Park Mixed-Use Opportunity

Double commercial lot in Winter Park, FL, for lease.

5589 LAKE HOWELL ROAD, Winter Park, FL 32792
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Greenville, SC Medical Office Space Leasing Opportunities Market Analysis

Explore Medical Office Space leasing options in Greenville, SC with 14 listings featured on our commercial real estate exchange. The current inventory includes 1,542,851,640 square feet of properties with an estimated lease value of $106 SF/Yr.

Estimated lease rates for Medical Office Space in Greenville, SC begin at $12 SF/Yr, with an average of $21 SF/Yr and extend to $30 SF/Yr.
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