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    Greenville, SC
    Medical Space

    Greenville, SC Medical Office Space for Lease

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    Taylors, SC Greer, SC Mauldin, SC Simpsonville, SC Travelers Rest, SC Piedmont, SC Easley, SC Duncan, SC
    10 properties
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    Greenville Office/Medical Space For Rent
    Updated: Nov 25, 2025
    Greenville Office/Medical Space For Rent

    20 Creekview Ct, Greenville, SC

    $1,275/Mo
    1,005 sqft
    Located in the desirable Roper Mountain area.
    Ideal for Medical or Office use.
    Plenty of Parking available.
    Suitable for Mental Health/Alternative Medicine or General Office Use.
    Features a Medical Sink and Cabinetry.
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    Medical Office Space For Lease
    Updated: Sep 25, 2025
    Medical Office Space For Lease

    3535 Pelham Road, Greenville, SC 29615

    $13.95 SF/Yr
    8,000 sqft
    Prime location on Pelham Road corridor in Greenville County.
    Convenient access: Less than a mile to I‑85.
    Medical office space suitable for various practices.
    Flexible space: Can be divided to suit tenant needs.
    Features 9 private offices, 2 conference rooms, lobby, and break room.
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    Medical Office Space For Lease
    Medical Office Space For Lease

    10 Enterprise Blvd., Greenville, SC 29615

    $26.50 SF/Yr
    45,200 sqft

    Medical office space near Prisma Health Patewood & Bon Secours.

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    Medical Office Building in Medical Park
    Medical Office Building in Medical Park

    10 Memorial Medical Drive, Greenville, SC 29605

    Contact for pricing
    7,000 sqft

    Medical office building in Memorial Medical Park near I-185, offering space for healthcare practices or related offices.

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    Prime Medical Office Space
    Prime Medical Office Space

    800 Pelham Rd, Greenville, SC

    $18 SF/Yr
    15,448 sqft

    Eastside Greenville location near Prisma and Bon Secours campuses.

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    Second-Generation Medical Office Space
    Second-Generation Medical Office Space

    701 Congaree Rd, Greenville, SC 29607

    Contact for pricing

    Second-generation medical and professional office with existing exam rooms, patient waiting areas, and administrative offices.

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    Lower-Level Office Suite with Lab Room
    Lower-Level Office Suite with Lab Room

    1405 Grove Road, Greenville, SC 29605

    Contact for pricing

    Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

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    Medical Office Space Available
    Medical Office Space Available

    300 Regent Park Ct, Greenville, SC 29607

    Contact for pricing

    Office spaces for healthcare providers near I-385 & Butler Rd.

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    Greenville Office Space For Rent
    Greenville Office Space For Rent

    127 Halton Village Cir, Greenville, SC

    $23 SF/Yr
    5,600 sqft

    Flexible office space near Patewood Medical Campus available for rent.

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    Medical Office Space Near Hospital
    Medical Office Space Near Hospital

    1200 W Faris Rd, Greenville, SC 29605

    Contact for pricing
    4,232 sqft

    Stand-alone building ideal for medical use near Greenville Memorial.

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    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 10 Active listings in Greenville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Turn-Key ADA Accessible Professional Office
    Turn-Key ADA Accessible Professional Office

    106 MEMORIAL DR, Greer, SC 29650

    Contact for pricing
    1,442 sqft

    Newly remodeled office with reception, three private offices, lounge, kitchen, and 10 on-site parking spaces.

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    Retail or Office Suite
    Retail or Office Suite

    5823 Calhoun Memorial Highway, Easley, SC 29640

    Contact for pricing
    1,211 sqft

    Suite 1A provides flexible retail or office space within a highly visible shopping center with ample parking.

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    Turn Key Medical Office Space
    Turn Key Medical Office Space

    100 Constantine Wy, Greer, SC

    $23 SF/Yr
    5,000 sqft

    New construction medical office space in close proximity to airport.

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    Medical Office Building For Rent
    Medical Office Building For Rent

    109 Fleetwood Dr, Easley, SC 29640

    $11 SF/Yr
    18,631 sqft

    Medical office building offering approximately 18,631 square feet for lease.

    View details

    Similar Spaces for Sale in Greenville, SC

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Absolute NNN Dental Office
    Absolute NNN Dental Office

    1173 Ashmore Bridge Rd, Greenville, SC 29605

    $4,160,000
    4,200 sqft

    Newly delivered dental office offered on an Absolute NNN basis with a long-term lease and corporate guarantee.

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    Freestanding Office Building For Sale
    Freestanding Office Building For Sale

    5 Hawthorne Park Ct, Greenville, SC 29615

    $1,650,000
    6,046 sqft

    Freestanding office building in desirable Eastside office corridor.

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    Multi-Tenant Office Building
    Multi-Tenant Office Building

    25 Sweetbriar Rd, Greenville, SC 29615

    Contact for pricing
    21,750 sqft

    Multi-tenant office building with multiple suites, unfinished storage, and 71 parking spaces, offered via online auction.

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    Medical Office Building with Rental Income
    Medical Office Building with Rental Income

    9 Hawthorne Park Court, Greenville, SC 29605

    Contact for pricing

    Medical office building for sale with a current tenant, Brio Internal Medicine, and rental income through September 2021.

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    Single-Tenant Medical Office Building
    Single-Tenant Medical Office Building

    13 Edgewood Dr, Greenville, SC 29605

    Contact for pricing

    Fully leased orthopedic outpatient clinic building used by Prisma Health.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

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    Prime Commercial Lot For Rent
    Prime Commercial Lot For Rent

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    0.66 acre commercial lot with high visibility.

    View details
    Prime Lexington Outlot Opportunity
    Prime Lexington Outlot Opportunity

    3330 Partner Place, Lexington, KY 40503

    Contact for pricing

    Outlot for ground lease or build-to-suit in South Lexington.

    View details
    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft

    1.7 acre corner lot zoned for commercial, medical, residential.

    View details

    Greenville, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Greenville, SC with 10 listings featured on our commercial real estate exchange. The current inventory includes 75,253 square feet of properties with an estimated lease value of $96.67 SF/Yr.

    Estimated lease rates for Medical Office Space in Greenville, SC begin at $13.95 SF/Yr, with an average of $19.33 SF/Yr and extend to $26.50 SF/Yr.
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    Most Searched ZIP Codes in Greenville, SC

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    • 29607
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