Add Listing
    Greenville, SC
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent
    $
    $
    Size
    Property Size / SF

    Greenville, SC Medical Office Space for Lease

    Notify Me
    List
    Map
    Taylors, SC Greer, SC Mauldin, SC
    13 results
    Medical Office Space For Lease
    $26 SF/Yr
    45,200 SF
    Medical Office Space For Lease

    10 Enterprise Blvd., Greenville, SC 29615

    Medical office space near Prisma Health Patewood & Bon Secours.
    • Prime Location: One block from Prisma Health Patewood Campus & Bon Secours Francis Eastside.
    • Medical/Healthcare Focus: Ideal office space for medical or healthcare practices.
    • Flexible Lease Terms: Adaptable lease options to suit tenant needs.
    • Available Space: 1,634 - 3,297 SF available, offering options for different sized practices.
    • Renovated Common Areas: Updated and well‑maintained shared spaces.
    Updated: Jan 27
    View details
    Medical Office Space For Lease
    $13 SF/Yr
    8,000 SF
    Medical Office Space For Lease

    3535 Pelham Road, Greenville, SC 29615

    Medical office space for lease in Greenville, South Carolina.
    • Prime location on Pelham Road corridor in Greenville County.
    • Convenient access: Less than a mile to I‑85.
    • Medical office space suitable for various practices.
    • Flexible space: Can be divided to suit tenant needs.
    • Features 9 private offices, 2 conference rooms, lobby, and break room.
    Updated: Sep 25, 2025
    View details
    Turnkey Healthcare Suite Available
    Contact for pricing
    Turnkey Healthcare Suite Available

    Ready-to-occupy medical suite with excellent visibility and accessibility.

    2709 Pelham Road, Greenville, SC 29615

    View details
    Greenville Medical Office Space
    $30 SF/Yr
    2,600 SF
    Greenville Medical Office Space

    Modern medical office space available for lease in Greenville, SC.

    3807 White Horse Rd, Greenville, SC

    View details
    Medical Office Near Greenville Memorial
    $18 SF/Yr
    22,786 SF
    Medical Office Near Greenville Memorial

    Medical office space for rent near Greenville Memorial Hospital.

    8 Memorial Medical Ct, Greenville, SC

    View details
    Medical Office Space For Lease
    $18 SF/Yr
    3,000 SF
    Medical Office Space For Lease

    Medical office space available for lease in Greenville, SC.

    274 B Commonwealth Drive, Greenville, SC 29615

    View details
    Prime Medical Office Space
    $18 SF/Yr
    15,448 SF
    Prime Medical Office Space

    Eastside Greenville location near Prisma and Bon Secours campuses.

    800 Pelham Rd, Greenville, SC

    View details
    Medical Office Space For Rent
    Contact for pricing
    1,336 SF
    Medical Office Space For Rent

    Newly renovated medical office space in Greenville's medical corridor.

    62 Bear Dr, Greenville, SC

    View details
    Two-Story Office Building Available
    Contact for pricing
    5,500 SF
    Two-Story Office Building Available

    Two-story office building with ample parking and multiple access points.

    501 Roper Mountain Rd, Greenville, SC

    View details
    Lower-Level Office Suite with Lab Room
    Contact for pricing
    Lower-Level Office Suite with Lab Room

    Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

    1405 Grove Road, Greenville, SC 29605

    View details
    Medical Office Space Available
    Contact for pricing
    Medical Office Space Available

    Office spaces for healthcare providers near I-385 & Butler Rd.

    300 Regent Park Ct, Greenville, SC 29607

    View details
    Greenville Office Space For Rent
    $23 SF/Yr
    5,600 SF
    Greenville Office Space For Rent

    Flexible office space near Patewood Medical Campus available for rent.

    127 Halton Village Cir, Greenville, SC

    View details
    Medical Office Space Near Hospital
    Contact for pricing
    4,232 SF
    Medical Office Space Near Hospital

    Stand-alone building ideal for medical use near Greenville Memorial.

    1200 W Faris Rd, Greenville, SC 29605

    View details
    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 13 Active listings in Greenville, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    334,000 SF Office Building For Lease
    $19 SF/Yr
    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

    View details
    Turn Key Medical Office Space
    $23 SF/Yr
    5,000 SF
    Turn Key Medical Office Space

    New construction medical office space in close proximity to airport.

    100 Constantine Wy, Greer, SC

    View details
    Simpsonville Retail Space For Lease
    Contact for pricing
    7,500 SF
    Simpsonville Retail Space For Lease

    Up to 7,500 SF retail space in Simpsonville, SC.

    721 SE Main St, Simpsonville, SC 29681

    View details
    Greer Retail & Restaurant Space
    Contact for pricing
    2,400 SF
    Greer Retail & Restaurant Space

    Retail, restaurant, and medical office spaces available for lease.

    2000 Hwy 101 S, Greer, SC

    View details

    Similar Spaces for Sale in Greenville, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Medical Office Building For Sale
    $2,395,000
    7,397 SF
    Medical Office Building For Sale

    Two-story, ±7,397 SF medical office building suited for owner-occupant.

    300 Regent Park Ct, Greenville, SC

    View details
    Medical Office Near Unity Park
    Contact for pricing
    4,076 SF
    Medical Office Near Unity Park

    Medical office space for sale near Unity Park.

    20 Mayfield Street, Greenville, SC 29601

    View details
    Freestanding Office Building For Sale
    $1,700,000
    6,046 SF
    Freestanding Office Building For Sale

    Freestanding office building in desirable Eastside office corridor.

    5 Hawthorne Park Ct, Greenville, SC 29615

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing
    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607

    View details
    Prime Commercial Lot For Rent
    $7,500/Mo
    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794

    View details
    Prime Lexington Outlot Opportunity
    Contact for pricing
    Prime Lexington Outlot Opportunity

    Outlot for ground lease or build-to-suit in South Lexington.

    3330 Partner Place, Lexington, KY 40503

    View details
    Beaumont Centre Outparcel Opportunity
    Contact for pricing
    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

    3199 Beaumont Centre Circle, Lexington, KY 40513

    View details

    Greenville, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Greenville, SC with 13 listings featured on our commercial real estate exchange. The current inventory includes 102,634 square feet of properties with an estimated lease value of $147 SF/Yr.

    Estimated lease rates for Medical Office Space in Greenville, SC begin at $13 SF/Yr, with an average of $21 SF/Yr and extend to $30 SF/Yr.
    List
    Map

    Browse Medical Office Space for Lease Near Greenville, SC

    Popular Searches in Greenville, SC

    Popular Categories

    Most Searched ZIP Codes in Greenville, SC

    • 29615
    • 29605
    • 29607

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!