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    North Charleston, SC Medical Office Space for Lease

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    Charleston, SC Hanahan, SC Summerville, SC
    7 results
    North Charleston Office Space Available
    $19 SF/Yr
    1,664 SF

    North Charleston Office Space Available

    2070 Northbrook Blvd, North Charleston, SC

    Office space for rent in North Rivers Business Center.

    • High Occupancy Rate (98%) indicating strong tenant demand and income stability
    • Diverse Tenant Mix including medical, government, and professional office users
    • Presence of well‑known tenants such as MUSC Children's Health Clinic and Roper St. Francis ATI
    • Strategic Location with accessibility from Rivers Avenue and Northbrook Blvd
    • Includes two buildings totaling 79,611 SF
    Updated: Oct 29, 2025
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    Former Daycare Near Navy Yard
    Contact for pricing
    12,895 SF

    Former Daycare Near Navy Yard

    1910 McMillan Avenue, North Charleston, SC 29405

    12,895 SF former daycare near new Navy Yard.

    • Located just outside the new Navy Yard redevelopment project (retail, office, residential, mixed‑use).
    • ±12,895 SF former daycare suitable for daycare/preschool, medical/professional office, church, or financial service institution.
    • $546k of New FF&E and Tenant Improvements since 2022, including a new roof and 3 replaced HVAC Units (9 total).
    • Occupancy for 300 Total Children.
    • Proximity to the Lowcountry Rapid Transit System (coming in 2026).
    Updated: Mar 6
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    Class A Medical Office Space
    $30 SF/Yr
    1,647 SF

    Class A Medical Office Space

    Premier medical office space near Roper St. Francis Hospital.

    4600 Goer Dr, North Charleston, SC
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    First-Generation Office and Medical Suites
    Contact for pricing
    6,500 SF

    First-Generation Office and Medical Suites

    Flexible, suite-divisible two-story space on a busy commercial corridor with landlord-provided shell build-out.

    8471 Dorchester Road, North Charleston, SC 29420
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    Medical Office Suite
    Contact for pricing
    1,880 SF

    Medical Office Suite

    Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

    3210 Landmark Drive, North Charleston, SC 29418
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    Medical/Professional Office Suite For Rent
    $4,078/Mo
    1,830 SF

    Medical/Professional Office Suite For Rent

    1,830 SF medical/professional office suite near Trident Hospital Campus.

    2831 Tricom St, North Charleston, SC
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    North Charleston Office Space Available
    $25 SF/Yr
    903 SF

    North Charleston Office Space Available

    Professional office space for lease in North Charleston, SC.

    8700 North Park Boulevard, North Charleston, SC
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 7 Active listings in North Charleston, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class A Medical Office Space
    Contact for pricing
    12,000 SF

    Class A Medical Office Space

    Class A medical/general office space in Nexton mixed-use development.

    655 Scholar Way, Summerville, SC 29486
    View details
    West Ashley Medical Office Sublease
    $32 SF/Yr
    3,746 SF

    West Ashley Medical Office Sublease

    3,746 SF medical office space available for immediate sublease.

    2270 Ashley Crossing Ln, Charleston, SC
    View details
    Professional Office Suite For Rent
    Contact for pricing
    853 SF

    Professional Office Suite For Rent

    Professional office suite suitable for small business or medical practice.

    310 N Gum Street # A, Summerville, SC 29483
    View details
    Medical Office Space Available
    $35 SF/Yr
    18,000 SF

    Medical Office Space Available

    Medical office space for rent in Charleston's growing submarket.

    2620 Clements Ferry Rd, Charleston, SC
    View details

    Similar Spaces for Sale in North Charleston, SC

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Former Daycare Near Navy Yard
    $2,300,000
    12,895 SF
    Former Daycare Near Navy Yard

    12,895 SF former daycare near new Navy Yard project.

    1910 McMillan Avenue, North Charleston, SC 29405

    View details
    Dorchester Road Office Space Available
    $1,150,000
    6,600 SF
    Dorchester Road Office Space Available

    High-traffic location with flexible spaces for professional uses.

    7880-7890 Dorchester Rd, North Charleston, SC

    View details
    North Charleston Medical Office Building
    $1,500,000
    4,345 SF
    North Charleston Medical Office Building

    Commercial property suitable for medical or professional office use.

    3800 Faber Place Drive, North Charleston, SC 29405

    View details
    Renovated Office Building Near I-26
    Contact for pricing
    71,711 SF
    Renovated Office Building Near I-26

    71,354 SF office building with recent $2M renovation.

    4975 Lacross Road, North Charleston, SC 29406

    View details
    White Hall Center Office Condo
    $549,900
    2,000 SF
    White Hall Center Office Condo

    Office condo in White Hall Center, North Charleston.

    5401 Netherby Lane Ste 102, North Charleston, SC 29420

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
    View details
    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    WINTER PARK Land Lease Opportunity
    $8,500/Mo
    23,056 SF

    WINTER PARK Land Lease Opportunity

    Commercial land lease opportunity in Winter Park, Florida.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details

    North Charleston, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in North Charleston, SC with 7 listings featured on our commercial real estate exchange. The current inventory includes 6,044 square feet of properties with an estimated lease value of $101 SF/Yr.

    Estimated lease rates for Medical Office Space in North Charleston, SC begin at $19 SF/Yr, with an average of $25 SF/Yr and extend to $30 SF/Yr.
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