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    Spartanburg, SC Medical Office Space for Lease

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    Boiling Springs, SC Roebuck, SC Moore, SC Inman, SC Wellford, SC Cowpens, SC Duncan, SC Lyman, SC
    Class A Medical Office Suite
    Updated: Sep 8, 2025
    Class A Medical Office Suite

    1650 Skylyn Dr, Spartanburg, SC 29307

    Contact for pricing
    2,132 sqft
    Suite 380 with 2,132 SF Class A medical office
    NNN lease in place
    Ample parking on‑site
    On‑site gym with pool and snack bar
    Close to new Drayton Mills mixed‑use development
    View details
    Westside Office/Medical Space Available
    Updated: Jul 4, 2025
    Westside Office/Medical Space Available

    225 E Blackstock Rd, Spartanburg, SC

    Contact for pricing
    5,461 sqft 0.94 AC lot
    5461 ± sq. ft. office/medical space
    Convenient westside location, ½ mile from I‑26
    Includes reception, 2 private offices, 5 exam rooms & breakroom
    Benefit from a lead lined X‑Ray room
    Features 4 restrooms
    View details
    Class A Medical Office Space
    Class A Medical Office Space

    1650 Skylyn Dr, Spartanburg, SC 29307

    Contact for pricing

    Premier medical office space with wellness amenities and convenient location.

    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 3 Active listings in Spartanburg, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Turn-Key ADA Accessible Professional Office
    Turn-Key ADA Accessible Professional Office

    106 MEMORIAL DR, Greer, SC 29650

    Contact for pricing
    1,442 sqft 0.32 AC lot

    Newly remodeled office with reception, three private offices, lounge, kitchen, and 10 on-site parking spaces.

    View details
    Medical Office Space For Rent
    Medical Office Space For Rent

    3610 Moore Duncan Hwy, Moore, SC 29369

    Contact for pricing
    5,200 sqft

    Medical office space with high visibility and easy access.

    View details
    Turnkey Office Units
    Turnkey Office Units

    1791 E. Blackstock Rd., Moore, SC 29369

    Contact for pricing

    Designed for professional, medical, dental, insurance, and administrative operations with limited buildout requirements.

    View details
    Turn Key Medical Office Space
    Turn Key Medical Office Space

    100 Constantine Wy, Greer, SC

    Contact for pricing
    5,000 sqft 0.61 AC lot

    New construction medical office space in close proximity to airport.

    View details

    Similar Spaces for Sale in Spartanburg, SC

    Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

    Spartanburg Office Building For Sale
    Spartanburg Office Building For Sale

    130 Dillon Drive, Spartanburg, SC 29307

    $1,450,000
    7,200 sqft

    7,200 SF office building near Spartanburg Medical District.

    View details
    Medical/Professional Office Space Available
    Medical/Professional Office Space Available

    125 Dillon Dr, Spartanburg, SC 29307

    Contact for pricing
    10,000 sqft 1.30 AC lot

    10,000 SF property near Mary Black Regional Hospital.

    View details
    Medical Office Building with Parking
    Medical Office Building with Parking

    1776 Skylyn Dr, Spartanburg, SC 29307

    Contact for pricing
    11,832 sqft

    Medical office building with numerous exam, treatment, and procedure rooms and ample on-site parking.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing
    1.27 AC lot

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    View details

    Spartanburg, SC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Spartanburg, SC with 3 listings featured on our commercial real estate exchange. The current inventory includes 7,593 square feet of properties.
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