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    Hilton Head Island, SC Medical Office Space for Lease

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    Columbia, SC Greenville, SC Spartanburg, SC
    Medical Building on Hilton Head
    $22 SF/Yr

    Medical Building on Hilton Head

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

    Stand-alone medical building for lease on Hilton Head Island.

    • Stand‑alone medical building, ideal for medical or wellness users.
    • Prime location on Main Street, North End of Hilton Head Island, with easy access to Highway 278.
    • Convenient access to Hilton Head Hospital and surrounding professional area.
    • Ground‑floor layout with multiple exam rooms, waiting area, and private offices.
    • Plumbing in place for additional exam or treatment rooms.
    Updated: Mar 5
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    North End Hilton Head Offices
    $22 SF/Yr

    North End Hilton Head Offices

    100 Exchange Street, Hilton Head Island, SC 29926

    Professional office/medical spaces for lease on Hilton Head Island.

    • Professional office/medical spaces for lease in the South State Bank building.
    • Prime location on the north end of Hilton Head Island, fronting William Hilton Parkway and Main Street.
    • Close proximity to Hilton Head Hospital.
    • Efficient layouts in all suites.
    • NNN included in the rent.
    Updated: Mar 5
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    Medical Suites in Hilton Head
    Contact for pricing

    Medical Suites in Hilton Head

    Medical office suites for lease in prestigious medical complex.

    Hilton Head Island, SC 29926
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    Medical Suites in Hilton Head
    Contact for pricing

    Medical Suites in Hilton Head

    Medical suites for lease in Hilton Head's medical district.

    25 Hospital Center Blvd, Hilton Head Island, SC 29926
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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 4 Active listings in Hilton Head Island, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

    Explore Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for lease on Highway 170.

    48 Terrace Drive, Okatie, SC 29909
    View details
    Bluffton Office/Medical Suites Available
    $28 SF/Yr
    3,870 SF

    Bluffton Office/Medical Suites Available

    Class A office and medical suites for rent in Bluffton.

    2 WESTBURY PKWY, Bluffton, SC
    View details
    Bluffton Retail/Office/Medical Building
    $35 SF/Yr

    Bluffton Retail/Office/Medical Building

    Pre-leasing single-story retail/office/medical building in the heart of Bluffton.

    128 Bluffton Road, 29910, SC, Bluffton, SC 29910
    View details
    Okatie Outpatient Surgery Center Shell
    Contact for pricing
    1,556 SF

    Okatie Outpatient Surgery Center Shell

    Shell space available in Okatie Outpatient Surgery Center.

    40-48 Okatie Center Blvd S, Okatie, SC
    View details

    Explore Similar Spaces for Sale in Hilton Head Island, SC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Hilton Head Office/Medical Space
    $375,000

    Hilton Head Office/Medical Space

    Office/Medical space for sale near Hilton Head Hospital.

    23 Main Street, Suite 303, Hilton Head Island, SC 29926
    View details
    Stand Alone Medical Office Building
    $1,348,000
    3,600 SF

    Stand Alone Medical Office Building

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
    View details
    Stand Alone Medical Building
    $1,348,000

    Stand Alone Medical Building

    Stand-alone medical building on Hilton Head Island for sale.

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926
    View details
    Two-Story Office Building on Hilton Head
    $1,950,000
    9,600 SF

    Two-Story Office Building on Hilton Head

    9,600 SF office building in prime Hilton Head location.

    5 Dunmore Court, Hilton Head Island, SC 29926
    View details
    Medical Office Suite Near Hospital
    Contact for pricing
    750 SF

    Medical Office Suite Near Hospital

    Ground floor medical office suite near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926
    View details
    Medical Office Suite Near Hospital
    Contact for pricing
    1,500 SF

    Medical Office Suite Near Hospital

    Ground floor medical office suite available near Hilton Head Hospital.

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Commercial Lot For Rent
    $7,500 /Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details
    Valdosta Commercial Land For Lease
    Contact for pricing
    43,560 SF

    Valdosta Commercial Land For Lease

    Prime commercial land in high-growth Valdosta corridor, suitable for various uses.

    0 Inner Perimeter Rd & Park Ave., Valdosta, GA 31602
    View details
    Winter Park Mixed-Use Opportunity
    $8,500 /Mo
    23,056 SF

    Winter Park Mixed-Use Opportunity

    Double commercial lot in Winter Park, FL, for lease.

    5589 LAKE HOWELL ROAD, Winter Park, FL 32792
    View details
    Highway 72 Corner Lot
    $6,500 /Mo
    1,875 SF

    Highway 72 Corner Lot

    1.6 acre commercial lot for rent on Highway 72.

    30472 Highway 72, Madison, AL 35756
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    Hilton Head Island, SC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Hilton Head Island, SC with 4 listings featured on our commercial real estate exchange. The current inventory includes 0 square feet of properties with an estimated lease value of $44 SF/Yr.

    Estimated lease rates for Medical Office Space in Hilton Head Island, SC begin at $22 SF/Yr, with an average of $22 SF/Yr and extend to $22 SF/Yr.
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    Browse Medical Office Space for Lease Near Hilton Head Island, SC

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    Most Searched ZIP Codes in Hilton Head Island, SC

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