Medical Space

Bluffton, SC Medical Office Space for Lease

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Office Suites with Highway Frontage
Updated: Jun 3
Office Suites with Highway Frontage

2 Westbury Park Way, Bluffton, SC 29910

$32 SF/Yr
3,870 sqft
2002‑built office property fronting Hwy 278 (Fording Island Road) with 250'+ highway frontage
2 suites available: 1,790 SF and 3,870 SF (total 5,660 SF)
Bluffton side of Hwy 278 with easy access to major thoroughfares
Ample on‑site parking for employees and visitors
Existing tenant mix includes medical, professional, institutional, and local tenants
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Turn-Key Medical Office Suite
Updated: Jul 7
Turn-Key Medical Office Suite

14 OAK FOREST RD, Bluffton, SC 29910

Contact for pricing
950 sqft
2003‑built 950‑SF medical office suite available for sublease and immediate occupancy
Includes waiting room, reception area with check‑in window, and a private reception office
Three patient/exam rooms for clinical or wellness services
Private restroom and kitchenette included in the suite
Ready for immediate occupancy with bright, modern finishes and light flooring
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Single-Story Retail Office Medical Building
Single-Story Retail Office Medical Building

128 Bluffton Rd, Bluffton, SC 29910

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2,730 sqft

Pre-leasing is underway for a single-story retail, office, and medical building with a planned Fall 2026 delivery.

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Single-Story Medical Office Retail
Single-Story Medical Office Retail

128 Bluffton Rd, Bluffton, SC 29910

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2,655 sqft

Pre-leasing single-story retail and office building planned for delivery in Fall 2026.

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Class A Office Medical Building
Class A Office Medical Building

5 Buck Island Rd, Bluffton, SC 29910

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17,525 sqft

Class A office and medical building with floor-to-ceiling windows and an interior elevator at a highway intersection.

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Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 5 Active listings in Bluffton, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Medical Office Suite with Private Offices
Medical Office Suite with Private Offices

1264 Ribaut Road, Beaufort, SC 29902

$2,845/Mo
0.01 AC lot

Open work area, data room, shower, and existing plumbing support varied professional uses.

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Medical Building on Hilton Head
Medical Building on Hilton Head

4101 Main St, Suite E & F, Hilton Head Island, SC 29926

$17 SF/Yr

Stand-alone medical building for lease on Hilton Head Island.

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Medical Office Suite with Plumbing
Medical Office Suite with Plumbing

1264 Ribaut Rd, Suite 302, Beaufort, SC 29902

Contact for pricing
1,484 sqft

Lease-ready suite offers flexible work areas, private offices, clinical plumbing, and a dedicated data room.

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Medical Office Suites
Medical Office Suites

25 Hospital Center Blvd, Hilton Head Island, SC 29926

Contact for pricing
2,774 sqft

Three-story medical pavilion offers multiple suite layouts for lease, connected by breezeway to Hilton Head Hospital.

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Similar Spaces for Sale in Bluffton, SC

Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

Highway 278 Frontage Office Building
Highway 278 Frontage Office Building

5 Buck Island Rd, Bluffton, SC 29910

Contact for pricing
8,800 sqft

Class A office/medical building on Highway 278 in Bluffton.

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Furnished Medical Office Space
Furnished Medical Office Space

102-4 Okatie Center Blvd S, Bluffton, SC 29909

$950,000

Ground-floor practice features exam rooms, patient amenities, storage, and ADA-compliant access.

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Bluffton Office/Medical Building For Sale
Bluffton Office/Medical Building For Sale

5 Buck Island Rd, Bluffton, SC 29910

Contact for pricing
17,525 sqft

Class A office/medical building fronting Highway 278 in Bluffton.

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Medical Office Suite
Medical Office Suite

4 Okatie Center Boulevard South, Okatie, SC 29909

Contact for pricing
3,075 sqft

Medical office suite available in Okatie Center, located just off Hwy 170 near the Hwy 278 interchange.

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Furnished Medical Office Suite
Furnished Medical Office Suite

4 Okatie Center Boulevard S, Bluffton, SC 29909

$950,000

Ground-floor medical office with patient-facing areas, substantial storage, and ADA-compliant access.

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Leased Office Building
Leased Office Building

10 Plantation Park Drive, Bluffton, SC 29910

Contact for pricing
10,219 sqft

Multi-tenant office property with established occupants and proximity to Hilton Head Island.

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Leased Medical Office Space
Leased Medical Office Space

100b-14 Oak Forest Rd, Bluffton, SC 29910

$647,111

Family-practice space under a new NNN lease with annual increases and renewal options.

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Bluffton, SC Medical Office Space Lease Rates & Market Statistics

Explore 5 Medical Office Space listings for lease in Bluffton, SC on Realmo, a commercial real estate exchange covering the Bluffton area. The current inventory totals 27,730 square feet of properties.

Asking lease rates for Medical Office Space in Bluffton start at $32 SF/Yr, average $32 SF/Yr, and reach $32 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $32 SF/Yr is 47% above the South Carolina state average of $21.78 SF/Yr.

Bluffton accounts for 42% of the 12 medical office space listings currently available across Beaufort County, where nearby markets include Beaufort and Hilton Head Island. Medical Office Space listings make up 42% of the 12 Office Spaces currently for lease in Bluffton, with asking rates in line with the citywide Office Spaces average. Also worth a look for tenants weighing alternatives: Office Units (8 listings) elsewhere in the Bluffton market.

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