Realmo

Buy
- For Sale
- Post a Listing
Property Types
- Retail
  
  Automotive
  
  Gas Station
  
  Auto Shop
  
  Grocery Store
  
  Storefront
  
  Shopping Center
  
  Showroom
  
  Strip Mall
- Office
  
  Office Units
  
  Building
  
  Medical Premises
- Residential Income
  
  Multifamily
  
  Duplex
  
  Triplex
  
  Mobile Home & RV Parks
- Restaurants
  
  Conventional Restaurant
  
  Drive-through
- Industrial
  
  Flex Space
  
  Distribution Center
- Warehouse
- Mixed-Use
- Hospitality
  
  Hotel
- Health Care
  
  Medical Center
- Land
  
  Residential
  
  Commercial
  
  Recreation
  
  Industrial
  
  Agricultural
  
  Hunting
- Specialty
  
  Day Care Centers
  
  Church & Religious
Rent
- For Lease
- Post a Listing
Space Uses
- Retail
- Restaurant
- Office
- Medical Space
- Industrial
- Warehouse
- Flex
Analytics
- Analytics Center
- Insight Report
- Recently Sold
- Value Estimation
- Cap Rate
- Ownership Records
- Location Intelligence
- Business Placement
- Off-Market Leads
- Zoning Insight

Advertise Sign In

For Sale
- Retail
  - Automotive
  - Gas Station
  - Auto Shop
  - Grocery Store
  - Storefront
  - Shopping Center
  - Showroom
  - Strip Mall
- Office
  - Office Units
  - Building
  - Medical Premises
- Residential Income
- Restaurants
  - Conventional Restaurant
  - Drive-through
- Industrial
  - Flex Space
  - Distribution Center
- Warehouse
- Mixed-Use
- Hospitality
  - Hotel
- Health Care
  - Medical Center
- Land
  - Residential
  - Commercial
  - Recreation
  - Industrial
  - Agricultural
  - Hunting
- Specialty
  - Day Care Centers
  - Church & Religious
For Lease
- Retail
- Restaurant
- Office
- Medical Space
- Industrial
- Warehouse
- Flex
Analytics Center
Insight Report
Recently Sold
Value Estimation
Cap Rate
Ownership Records
Location Intelligence
Business Placement
Off-Market Leads
Zoning Insight
Advertise
Find Brokers

Florence, SC

Medical Space

Florence, SC Medical Office Space for Lease

List

Map

Darlington, SC Timmonsville, SC Hawthorne, FL Hartsville, SC Marion, SC Dillon, SC

Special-Use Office Building

Updated: Jun 19

Special-Use Office Building

191 South Cashua Drive, Florence, SC 29501

Contact for pricing

2,560 sqft 0.58 AC lot

Special‑use office building totaling 2,560 SF available September 2026
Former veterinary office layout suitable for medical, professional, service‑based, or specialty office use
Located on S Cashua Dr in Florence’s 5 Points commercial district in a high‑traffic area
On‑site parking includes nine lined spaces in front, with additional parking available at the rear
Set on a 0.58‑acre lot

Retail Space in Mixed-Use District

Updated: Mar 18

Retail Space in Mixed-Use District

2295 Hoffmeyer Rd, Florence, SC 29501

Contact for pricing

7,420 sqft

Anchored just off Hoffmeyer Road in West Florence as part of a mixed‑use redevelopment repurposing existing buildings.
Located on/near Hoffmeyer Rd (AADT 18,300+) and W. Darlington St (AADT 11,700+), with combined counts exceeding 30,000 VPD.
Minutes from the I‑95 & I‑20 interchange.
Positioned between Magnolia Mall and Florence Mall.
Adjacent to Palmetto Peddlers (30,000 SF, 130+ vendors).

Mixed-Use Retail and Office Space

Mixed-Use Retail and Office Space

2295 Hoffmeyer Rd, Florence, SC 29501

Contact for pricing

7,465 sqft

7,465-square-foot property within a redevelopment featuring retail, office, medical, dining, and lifestyle spaces.

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 3 Active listings in Florence, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Brand-New Medical Office with Exam Rooms

116 Professional Park Dr., Conway, SC 29526

$10,634/Mo

3,988 sqft

New brick medical suite with 9 exam rooms, dedicated HVAC for the computer room, and 25 parking spaces.

Retail Flex Building on Highway 378

Retail Flex Building on Highway 378

2673 Green Pond Circle, Conway, SC 29527

$22 SF/Yr

7,500 sqft

Seven retail flex units front Highway 378 with LED lighting and showroom windows, with flexible consolidation options.

Commercial Office/Medical Space For Lease

Commercial Office/Medical Space For Lease

6101-a-812 Candy Park Rd, Pembroke, NC 28372

$2,600/Mo

Commercial office/medical space featuring storage, reception, and multiple rooms.

Medical Office Space with Exam Rooms

Medical Office Space with Exam Rooms

812 Candy Park Lane, Pembroke, NC 28372

$2,600/Mo

Configured for clinical operations with patient reception, support areas, and dedicated storage.

Similar Spaces for Sale in Florence, SC

Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

Medical Office Building with 13 Exam Rooms

Medical Office Building with 13 Exam Rooms

1706 2nd Loop Rd., Florence, SC 29501

$1,650,000

8,291 sqft 1.34 AC lot

CI-zoned medical office facility with 13 exam rooms, covered patient drop-off, and 62 parking spaces.

Remodeled Office Building

Remodeled Office Building

910 W Evans st, Florence, SC 29501

$300,000

2,165 sqft 0.27 AC lot

Updated office property with private rooms, a modern kitchen, wood flooring, and two bathrooms.

Medical Office Building with Parking

Medical Office Building with Parking

1706 2nd Loop Rd., Florence, SC 29501

Contact for pricing

8,300 sqft 1.34 AC lot

Multi-room medical office building with 13 exam rooms, imaging room, and 62 parking spaces on 1.34 acres.

Two-Story Single-Tenant Medical Office

Two-Story Single-Tenant Medical Office

1604 E Cheves St, Florence, SC 29506

Contact for pricing

16,444 sqft

Fee simple interest in a purpose-built two-story medical office building, single-tenant and leased to a neurosurgery practice.

Fully Furnished Medical Office Suite

Fully Furnished Medical Office Suite

1523 Heritage Lane Unit B, Florence, SC 29505

$590,000

Medical office suite with four exam rooms, a treatment room, waiting areas, and on-site staff rooms.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Development Opportunity in Greenville

Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 AC lot

1.27 acre interstate-visible land for ground lease or build-to-suit.

General Business Retail Development Site

General Business Retail Development Site

Tift Avenue N, Tifton, GA 31794

$7,500/Mo

Approximately 0.66-acre commercial land parcel zoned GB General Business in Tifton.

Prime Lexington Outlot Opportunity

Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

Corner Office Unit

Corner Office Unit

30472 Highway 72, Madison, AL 35756

$5,000/Mo

1,875 sqft

C4 zoning allows commercial, medical, and residential uses at this accessible corner property.

Florence, SC Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Florence, SC with 3 listings featured on our commercial real estate exchange. The current inventory includes 17,445 square feet of properties.

List

Map