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Erie County, NY Medical Offices for Sale

48 results
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Derby, NY Commercial Opportunity
$99,900
1,016 SF

Derby, NY Commercial Opportunity

6850 Prescott Dr, Derby, NY 14047

Commercial building in Derby, NY, suitable for various uses.

  • Terrific location near Lakeshore, just off Route 5, offering high visibility.
  • Zoned GB, suitable for a variety of businesses including retail, insurance, accounting, law, or medical.
  • Multiple rooms on the first floor.
  • Office/storage space on the second floor.
  • Public water and sewer connections.
Updated: Sep 5, 2025
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Equipped Dental Office in Buffalo
$179,000
1,107 SF

Equipped Dental Office in Buffalo

646 N French #5 Rd, Buffalo, NY 14228

Fully equipped dental office with parking and easy access.

  • Fully equipped dental office ready for immediate use.
  • Ample parking and easy access from Sweethome or N. French Road.
  • Durable brick and concrete construction.
  • Efficient forced air heating with natural gas.
  • Public water and sewer connections.
Updated: Oct 15, 2025
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Historic Church with Multifaceted Potential
$999,900
16,438 SF

Historic Church with Multifaceted Potential

Versatile church property with medical suite and residential units.

360 Genesee St, Buffalo, NY 14204
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Updated Condominium on Maple Road
$325,000
2,100 SF

Updated Condominium on Maple Road

Updated condominium suitable for medical, accounting, or attorney offices.

37 Maple Rd, Buffalo, NY 14221
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Professional Office Building in Buffalo
Pending
$250,000
1,005 SF

Professional Office Building in Buffalo

Well-maintained 1,000 SF office building suitable for various business uses.

1616 Abbott Rd, Buffalo, NY 14218
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I-90 Regional Development Site
Contact for pricing
93,100 SF

I-90 Regional Development Site

Prime West Seneca medical office & development land

355 Orchard Park Rd, West Seneca, NY 14224
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Williamsville Medical Office Condo
$495,000
3,708 SF

Williamsville Medical Office Condo

Prime Main St location, 3708 SF, $495,000

6480 Main St, Williamsville, NY 14221
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Main Street Williamsville Office Building
$1,500,000
10,500 SF

Main Street Williamsville Office Building

10,500 SF Office, 60 Parking Spaces, $1.5M

6645 Main St, Williamsville, NY 14221
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Prime Buffalo Medical Office Building
$1,700,000
19,000 SF

Prime Buffalo Medical Office Building

19,000 SF Class A Medical Office, $1.7M

235 North St, Buffalo, NY 14201
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Executive Office Building, Buffalo
$1,800,000
12,000 SF

Executive Office Building, Buffalo

12,000 SF Office, Prime Location

2060 Sheridan Dr, Buffalo, NY 14223
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Boston Office Building - 3 Units
$340,000
3,744 SF

Boston Office Building - 3 Units

Mixed-use, 3,744 sq ft, great location.

8397 Boston State Rd, Boston, NY 14025
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Main Street Office Building
$2,300,000
33,000 SF

Main Street Office Building

33,000 SF Office Building, Buffalo, NY

1236 Main St, Buffalo, NY 14209
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Orion Plaza: Hamburg Mixed-Use Investment
$1,750,000
20,550 SF

Orion Plaza: Hamburg Mixed-Use Investment

High-yield, multi-tenant office complex

5893 Camp Rd, Hamburg, NY 14075
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Delaware Ave Office Building
$3,500,000
42,130 SF

Delaware Ave Office Building

42,130 SF Office Building, Buffalo, NY

560 Delaware Ave, Buffalo, NY 14202
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Depew Medical Office Building For Sale
$1,799,999
5,520 SF

Depew Medical Office Building For Sale

Prime Medical Office, 5,520 SF, High Traffic

6140 Transit Rd, Depew, NY 14043
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Lancaster Office/Retail Space for Sale
$309,900
1,600 SF

Lancaster Office/Retail Space for Sale

Prime Lancaster location, 1600 sq ft, vacant.

5294 Broadway, Lancaster, NY 14086
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Move-in Ready Dental Office
$550,000
1,482 SF

Move-in Ready Dental Office

Dental office in Hamburg, near retail and Highmark Stadium.

4931 Southwestern Blvd, Hamburg, NY 14075
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Remodeled Medical/Office Property in Elmwood Village
$899,999
2,643 SF

Remodeled Medical/Office Property in Elmwood Village

High-end medical/office property in Buffalo's Elmwood Village.

142 Bidwell Pkwy, Buffalo, NY 14222
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West Seneca Former Medical Office
Contact for pricing

West Seneca Former Medical Office

36,346 SF medical office space for sale/lease.

130 Empire Dr, West Seneca, NY 14224
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Corner Medical Office Investment Property
Contact for pricing
4,921 SF

Corner Medical Office Investment Property

Fully leased medical building with a strong, credit tenant.

2556 Delaware Ave, Buffalo, NY 14216
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Bailey Avenue Medical Office Buildings
$799,000
17,437 SF

Bailey Avenue Medical Office Buildings

Four vacant medical office buildings near University of Buffalo South Campus.

3435 Bailey Ave, Buffalo, NY 14215
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Union Road Medical Investment Property
$1,199,900
6,000 SF

Union Road Medical Investment Property

Cash flowing medical property with long-term tenant on Union Road.

2100 Union Rd, West Seneca, NY 14224
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Main Street Professional Office
$475,000
3,965 SF

Main Street Professional Office

Former medical office suitable for various professional uses.

8995 Main St, Clarence, NY 14031
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Amherst Office Building For Sale
Contact for pricing

Amherst Office Building For Sale

1,122 SF office building in a convenient, strategic location.

656 North French Rd, Amherst, NY 14228
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Erie County, NY Medical Offices Investment Opportunities Market Analysis

Explore 163 medical offices for sale in Erie County, NY, showcased through 48 active listings on our real estate platform. These investment opportunities span a total of 1,694,827 square feet of properties for sale, with an estimated market value of $33,408,700.

Prices for medical spaces in Erie County, NY start at $70,000, averaging $710,823, and reaching up to $6,105,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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