Seneca, SC Commercial real estate for Rent & Lease

Triple net (NNN)

Flex Space with Showroom

879 By Pass 123 Highway Includes 710 Seneca Dr, Seneca, SC 29678

Flex space

$2,000/Mo

3,264 sqft Built 1980

Two commercial buildings combine customer-facing space with office, service, and garage functionality under an NNN lease structure.

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Gross

Upper-Level Office Unit

205 Stork Way Upper Unit, Seneca, SC 29678

$1,300/Mo

7–12 people 1,800 sqft

Upper-level office space offers a separate stairway entrance, open layout, kitchenette, and full bathroom.

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Modified gross

Main Corridor Office Suite

114 Nimmons Circle, Seneca, SC 29678

$1,600/Mo

6–10 people 1 space 1,500 sqft

Bottom-floor office suite with multiple offices, conference room, reception, two restrooms, and storage, with front parking and signage.

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Office Units With Suite Options

402 Cane Creek Landing Road, Seneca, SC 29672

$26.26-$74.38 SF/Yr

4 spaces

Flexible leasing includes private offices, floor suites, and full-building occupancy with shared conference and reception areas.

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Service Garage with Storage Loft

710 Seneca Drive, Seneca, SC 29678

Auto shop

$2,000/Mo

3,264 sqft

A service garage includes office, parts room, loft storage, and roll-up doors.

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Retail Storefront in Shopping Center

1640 Sandifer Boulevard, Seneca, SC 29678

Storefront property

Contact for pricing

2,550 sqft

Storefront suite in a signalized shopping center entrance with about 130 feet of frontage on Sandifer Blvd.

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Insulated Flex Space with Office

615 E S FIRST ST, Seneca, SC

Flex space

Contact for pricing

4,400 sqft

The office area offers four to five offices, two bathrooms, and recently installed HVAC units.

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Flex Space with Office

615 East South 1st Street, Seneca, SC 29678

Flex space

Contact for pricing

27,449 sqft

The office area contains four to five offices and two bathrooms.

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Five-Office Commercial Suite

100 Century Plaza Drive #Suite G-7, Seneca, SC 29678

$1,000/Mo

5–8 people 1,250 sqft

A freshly painted workspace includes a reception area, break room, and separate front and rear building access.

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Built-Out Medical Office Suite

205 Central Park Ln, Seneca, SC 29678

Medical Office Space

$17.50 SF/Yr

Built 2007

Fully built-out suite with clinical rooms, reception, conference space, and staff amenities.

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Office Suite with Reception Area

815 Robin Drive #Suite 2, Seneca, SC 29678

$2,200/Mo

Built 1995

The owner covers utilities, taxes, and insurance for this Seneca office space.

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Furnished Office Unit

10 Accountants Circle, Seneca, SC 29678

Contact for pricing

Professional suite with nearby restroom, break room access, parking, and optional office furnishings.

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Second-Floor Office Suite with Balcony

202-1510 Blue Ridge Blvd, Seneca, SC 29672

$3,000/Mo

Second-floor suite with five private offices, a kitchen area, and two private bathrooms, plus shared lobby access and a balcony.

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Retail Suite with Showroom

10139 Clemson Boulevard #B, Seneca, SC 29678

Retail space

$1,950/Mo

3,400 sqft

A large open showroom area is complemented by private offices, closets, a side entrance, and a bathroom with shower.

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Open-Plan Retail Space

1526 Blue Ridge Boulevard, Seneca, SC 29672

Retail space

$1,500/Mo

1,900 sqft

A rear roll-up door and two restrooms support flexible use of the open interior.

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Retail Redevelopment Site

1637 Sandifer Blvd, Seneca, SC 29678

Retail space

Contact for pricing

Freestanding retail site with full access along Sandifer Blvd and cross access to Stop-A-Minit.

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Highway-Facing Office Suite

100 Century Plaza Drive #Suite E-5, Seneca, SC 29678

$2,100/Mo

8–14 people 2,100 sqft

A multi-room office layout includes a conference room, reception area, storage, and two bathrooms.

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Commercial Land Outparcel

285 Applewood Center Pl, Seneca, SC 29678

Commercial land

Contact for pricing

Build-to-suit or ground-lease options are available within a Belk-anchored shopping center.

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Flex Space

4058 Keowee School Road, Seneca, SC 29672

Flex space

$2,000/Mo

Built 2006

The space can support storage, mechanical work, or warehousing.

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Based on your search, we've compiled 55 Potential Opportunities for your consideration. Besides 19 Active listings in Seneca, SC, we suggest exploring alternatives. Similar 36 Properties for Sales.

Similar Spaces for Sale in Seneca, SC

Consider Similar Space for Sale. We found 36 Spaces matching your search parameters.

Dual-Storefront Restaurant Property

124 And 118 N Townville Street Ye Ole Restaurant, Seneca, SC 29678

$799,000

5,772 sqft

Two storefront spaces provide restaurant, confectionery, and banquet-room functionality for food and event operations.

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Downtown Retail Building with Two Units

319 Main Street, Seneca, SC 29678

$1,500,000

5,500 sqft 0.24 AC lot

Two fully heated and air-conditioned retail units with private entrances and restrooms, plus street-to-street rear access.

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Two-Story Storefront Property

110 E N 1st Street, Seneca, SC 29678

$429,943

5,000 sqft

Downtown setting near shops, restaurants, and community events.

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Five-Office Professional Office Suite

C-528 By Pass 123, Seneca, SC 29678

$375,000

1,290 sqft

Move-in-ready workspace includes reception, kitchenette, and an ADA-accessible restroom.

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Professional Office Suite

528 ByPass 123, Seneca, SC 29678

$375,000

1,290 sqft

Flexible professional workspace with private offices, reception, kitchenette, and an ADA-accessible restroom.

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