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    Clemson, SC

    Clemson, SC Commercial Real Estate for Lease

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    6 properties
    Below-Boutique Retail Space
    Updated: Jun 12, 2025
    Below-Boutique Retail Space

    382 College Avenue, Clemson, SC 29631

    $2,800/Mo
    Approx. 2,100 SF of finished space
    Former Grace Coffee Shop location, currently below The Fizz Boutique
    Accessible from Kieth St
    Brick construction with tile flooring
    Central heating and central air conditioning
    View details
    First-Floor Retail and Office Suites
    Updated: Jul 13
    First-Floor Retail and Office Suites

    125 Anderson Highway, Clemson, SC 29631

    $25 SF/Yr
    GrandMarc Clemson built in 2017: 150‑room, 500‑bed student housing community with three first‑floor suites available.
    High‑traffic setting on SC‑28 (Anderson Highway) with approximately 12,400 vehicles per day.
    Clemson University campus is less than 1 mile away; property is near Littlejohn Coliseum (150+ events annually).
    Available suites for lease: Unit B 3,391 SF, Unit C 3,947 SF, and Unit E 2,053 SF.
    Suites available individually or in combination for larger tenant space needs.
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    Retail Space Near Clemson University
    Retail Space Near Clemson University

    1390 Tiger Blvd, Clemson, SC

    Contact for pricing
    1,233 sqft

    Publix-anchored retail space with high visibility near Clemson University.

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    Mixed-Use Property Near Clemson Campus
    Mixed-Use Property Near Clemson Campus

    111 Earle Street, Clemson, SC 29631

    Contact for pricing

    Mixed-use property with residential and retail components near Clemson University.

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    Retail/Restaurant Space Near Clemson University
    Retail/Restaurant Space Near Clemson University

    114 Earle St, Clemson, SC

    Contact for pricing
    1,401 sqft

    Retail/restaurant spaces available in mixed-use student housing project.

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    Retail Space Near Clemson University
    Retail Space Near Clemson University

    107 Canoy Ln, Clemson, SC 29631

    Contact for pricing

    Retail space on high-traffic corridor near Clemson University.

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    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 6 Active listings in Clemson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 10 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Historic Retail Space with Courtyard Access
    Historic Retail Space with Courtyard Access

    104 Exchange Street, Pendleton, SC 29670

    $3,500/Mo
    1,550 sqft

    One-level retail space and annex under historic renovation, with courtyard access for customer seating and programming.

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    Seneca Office Space For Lease
    Seneca Office Space For Lease

    865 Old Clemson Highway, Seneca, SC 29678

    $1,500/Mo

    Two-level office building suitable for various businesses, near Clemson.

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    Retail Space with Open Layout
    Retail Space with Open Layout

    125 N Mechanic St, Pendleton, SC 29670

    $19 SF/Yr

    Retail space featuring an open layout and additional storage.

    View details
    Land Near Oconee Medical Center
    Land Near Oconee Medical Center

    15516 Wells Hwy, Seneca, SC

    Contact for pricing

    Commercial land for rent near medical center and Clemson University.

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    Similar Spaces for Sale in Clemson, SC

    Consider Similar Space for Sale. We found 10 Spaces matching your search parameters.

    Multi-Tenant Retail Property with Unfinished Basement
    Multi-Tenant Retail Property with Unfinished Basement

    203 Pendleton Road, Clemson, SC 29631

    $1,500,000
    0.88 AC lot

    Multi-tenant retail building with ample parking and an unfinished basement, offering flexible space for investors or owner-occupants.

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    Multi-Tenant Retail Building
    Multi-Tenant Retail Building

    203 Pendleton Road, Clemson, SC 29631

    $1,500,000
    7,000 sqft 0.88 AC lot

    Multi-tenant retail building with ample parking and an unfinished basement, located on highly visible Pendleton Road.

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    Retail Building with Ample Parking
    Retail Building with Ample Parking

    990 Tiger Boulevard, Clemson, SC 29631

    $1,349,990
    0.48 AC lot

    A sizable retail building positioned on a high-traffic highway with ample parking for customer access.

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    Clemson Land for Development
    Clemson Land for Development

    76 Highway, Clemson, SC 29631

    $1,299,774
    7.66 AC lot

    7+ acres of land near Clemson University.

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    Commercial Building on Highway 123
    Commercial Building on Highway 123

    990 Tiger Blvd, Clemson, SC 29631

    $1,349,990
    6,000 sqft 0.48 AC lot

    6000 sq ft commercial building with ample parking.

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    Ground-Floor Retail and Office Suites
    Ground-Floor Retail and Office Suites

    125 Anderson Highway, Clemson, SC 29631

    Contact for pricing

    Three ground-level suites are available within a 2017 student housing community on Clemson’s primary corridor.

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    Clemson Development Opportunity
    Clemson Development Opportunity

    W HWY 76, Clemson, SC 29631

    $1,299,774
    7.66 AC lot

    7+ acres zoned for hotel or multifamily development near Clemson.

    View details
    Land for Medical Office Building
    Land for Medical Office Building

    105 Chapman Hill Rd, Clemson, SC

    $499,000
    0.37 AC lot

    Land available with approved plans for medical office building.

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    Clemson Land Parcels Available
    Clemson Land Parcels Available

    608 Issaqueena Trl, Clemson, SC

    Contact for pricing
    1.67 AC lot

    Two outparcels available in Clemson, South Carolina.

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    Commercial Land Available
    Commercial Land Available

    Central (, Clemson, SC 29630

    Contact for pricing

    Commercial land for sale in Clemson, SC.

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    Clemson, SC Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Clemson, SC with 6 listings featured on our commercial real estate exchange. The current inventory includes 6,134 square feet of properties with an estimated lease value of $25 SF/Yr.

    Estimated lease rates for Commercial real estate in Clemson, SC begin at $25 SF/Yr, with an average of $25 SF/Yr and extend to $25 SF/Yr.
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