For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Buffalo, NY Mixed-use Properties for Lease

7 results
List
Map
Elmwood Village Mixed-Use Building
Contact for pricing
20,000 SF

Elmwood Village Mixed-Use Building

448 Elmwood Ave, Buffalo, NY 14222

20,000 SF mixed-use building in Elmwood Village, Buffalo, NY.

  • Located in the Elmwood Village at the corner of Bryant Street
  • Luxury two bedroom two bath apartments on 2nd and 3rd floors
  • Retail opportunities on first floor
  • Gated Covered Parking available for apartments
  • 20,000 SF Mixed Use building
Updated: Nov 26, 2025
View details
New Retail Space in Buffalo
Contact for pricing

New Retail Space in Buffalo

386 Grant St, Buffalo, NY 14213

Brand new 700 sqft retail space in vibrant neighborhood.

  • Brand new 700 sqft retail space in a high‑visibility location on Buffalo's vibrant West Side.
  • Rent includes heating, cooling, water, and one off‑street parking space.
  • Modern design with 14 ft ceilings, exposed ductwork, polished concrete floors, and oversized storefront glass.
  • Delivered as a vanilla box, ready for customization with new HVAC, electrical service, and ADA restroom.
  • Part of a new mixed‑use building with high‑end apartments, geothermal heating/cooling, and solar panels.
Updated: Aug 19, 2024
View details
Eastern Hills Town Center Opportunity
Contact for pricing
200,000 SF

Eastern Hills Town Center Opportunity

Mixed-use development with office, retail, and residential spaces.

4545 Transit Rd, Buffalo, NY 14221
View details
Historic Mixed-Use Building Renovation
Contact for pricing

Historic Mixed-Use Building Renovation

Renovated mixed-use building with retail, office, warehouse, and apartments.

222 Chicago St, Buffalo, NY 14204
View details
Niagara Street Mixed-Use Complex
Contact for pricing

Niagara Street Mixed-Use Complex

Renovated mixed-use complex with high ceilings and signage opportunities.

1088 Niagara St, Buffalo, NY 14213
View details
Renovated Mixed-Use Building on Michigan
Contact for pricing

Renovated Mixed-Use Building on Michigan

Recently renovated mixed-use building with office and apartment spaces.

270 Michigan Ave, Buffalo, NY 14203
View details
Historic Landmark Mixed-Use Property
Contact for pricing

Historic Landmark Mixed-Use Property

Unique commercial and residential spaces in restored historic building.

1115 Main Rd, Buffalo, NY 14209
View details
Based on your search, we've compiled 87 Potential Opportunities for your consideration. Besides 7 Active listings in Buffalo, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 76 Properties for Sales.

Explore Mixed-use properties for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Commercial Building with Established Tenants
$525,000

Commercial Building with Established Tenants

Commercial building with restaurant and office/warehouse tenants in Tonawanda.

2829 Niagara St, Tonawanda, NY 14207
View details
Mixed-Use Building with Retail Space
Contact for pricing

Mixed-Use Building with Retail Space

Mixed-use building with retail and residential spaces, including Tim Hortons.

618 Delaware St, Tonawanda, NY 14150
View details
Mixed-Use Property on North French
Contact for pricing

Mixed-Use Property on North French

Retail, office, and restaurant space with luxury apartments available.

4750 N French Rd, East Amherst, NY 14051
View details
Move-in Ready Retail Space
Contact for pricing
1,080 SF

Move-in Ready Retail Space

1,080 SqFt retail space in East Amherst, New York.

4750-4840 N French Rd, East Amherst, NY 14051
View details

Explore Similar Spaces for Sale in Buffalo, NY

Consider Similar Space for Sale. We found 17 Spaces in Nearby Locations matching your search parameters.

Turn-Key Restaurant with Warehouse
$629,900
10,908 SF

Turn-Key Restaurant with Warehouse

Restaurant, renovated apartment, and warehouse for diverse income streams.

898 Genesee St, Buffalo, NY 14211
View details
Harlem Road Commercial Opportunity
$519,999
6,119 SF

Harlem Road Commercial Opportunity

6,119 Sqft building on 0.62-acre lot in high-traffic location.

1113- Harlem Rd, Buffalo, NY 14227
View details
Harlem Road Commercial Opportunity
$519,999
6,119 SF

Harlem Road Commercial Opportunity

High-traffic location suitable for office, retail, or mixed-use redevelopment.

1113- Harlem Rd, Buffalo, NY 14227
View details
Updated Mixed-Use Investment Opportunity
$449,900
7,748 SF

Updated Mixed-Use Investment Opportunity

Updated mixed-use property near Cazenovia Park with high income potential.

2342 Seneca St, Buffalo, NY 14210
View details
Mixed-Use Building in Seneca District
$449,900
4,515 SF

Mixed-Use Building in Seneca District

Mixed-use property with storefronts and updated apartments in Buffalo.

2096 Seneca St, Buffalo, NY 14210
View details
Main Street Mixed-Use Investment
$399,000
4,620 SF

Main Street Mixed-Use Investment

High-visibility mixed-use property with income potential on Main Street.

2290 Main St, Buffalo, NY 14214
View details
Elmwood Village Mixed-Use Investment
$449,000
4,746 SF

Elmwood Village Mixed-Use Investment

Mixed-use property in desirable location with income and appreciation potential.

1094 Elmwood Ave, Buffalo, NY 14222
View details
Mixed-Use Building in Hertel Business District
$950,000
10,320 SF

Mixed-Use Building in Hertel Business District

9-unit mixed-use building with storefronts and apartments in prime location.

1661 Hertel Ave, Buffalo, NY 14216
View details
Genesee Street Mixed-Use Redevelopment Opportunity
$570,000
12,720 SF

Genesee Street Mixed-Use Redevelopment Opportunity

Mixed-use property in Cheektowaga, NY, ideal for redevelopment.

2376 Genesee St, Buffalo, NY 14225
View details
Mixed-Use Investment Opportunity, Buffalo NY
$300,000
5,712 SF

Mixed-Use Investment Opportunity, Buffalo NY

Mixed-use property with retail and residential units for sale.

2364 Genesee St, Buffalo, NY 14225
View details
Renovated Mixed-Use Building, Buffalo
$499,000
2,626 SF

Renovated Mixed-Use Building, Buffalo

Fully renovated mixed-use building in a convenient Buffalo location.

970 Sycamore St, Buffalo, NY 14212
View details
Mixed-Use Property in Prime Location
$429,900
5,408 SF

Mixed-Use Property in Prime Location

Versatile property with commercial space and residential apartments.

41 Elmwood Ave, Buffalo, NY 14201
View details
Mixed-Use Investment Property in Buffalo
$224,900
4,001 SF

Mixed-Use Investment Property in Buffalo

Tenant-occupied mixed-use property with storefront and apartments in Buffalo.

1892 Seneca St, Buffalo, NY 14210
View details
Kaisertown Investment Opportunity
$219,900
4,656 SF

Kaisertown Investment Opportunity

Mixed-use property with storefront and residential units in Buffalo.

2047 Clinton St, Buffalo, NY 14206
View details
Kaisertown Investment Opportunity
$219,900
4,656 SF

Kaisertown Investment Opportunity

Mixed-use property with storefront and residential units in Buffalo.

2047 Clinton St, Buffalo, NY 14206
View details
Seneca Street Mixed-Use Investment Opportunity
$149,900
2,806 SF

Seneca Street Mixed-Use Investment Opportunity

Rehabbed mixed-use property with storefront and apartment near Cazenovia Park.

2346 Seneca St, Buffalo, NY 14210
View details
Updated Mixed-Use Investment Opportunity
$224,900
4,517 SF

Updated Mixed-Use Investment Opportunity

Mixed-use property with high cap rate and rental income.

1890 Seneca St, Buffalo, NY 14210
View details

Buffalo, NY Mixed-use properties Leasing Opportunities Market Analysis

Explore Mixed-use properties leasing options in Buffalo, NY with 7 listings featured on our commercial real estate exchange. The current inventory includes 9,583,200,000 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Mixed-use properties in Buffalo, NY begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
List
Map