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    Buffalo, NY Healthcare Properties for Sale

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    Accessible Two-Story Office Building
    Updated: May 21
    Accessible Two-Story Office Building

    1609 Genesee Street, Buffalo, NY 14211

    $499,900
    5,012 sqft 0.43 AC lot
    5,012 SF two‑story brick office building on a 0.43‑acre lot
    Valid Certificate of Occupancy with flexible office and multipurpose layouts
    Full elevator, wheelchair ramp, and wide hallways for accessible circulation
    Four bathrooms, with two on each floor, plus dedicated laundry areas
    Oversized parking lot with 25+ spaces and multiple entry points
    View details
    Historic Church Property with Medical Suite
    Updated: Aug 26, 2025
    Historic Church Property with Medical Suite

    360 Genesee Street, Buffalo, NY 14204

    $880,000
    16,438 sqft 0.87 AC lot
    0.87‑acre church property with 16,438 SF
    Built in 1832
    Bright sanctuary with ample seating
    Medical suite includes waiting room, conference room, and 5 exam rooms
    Complete kitchen and dining hall for events and gatherings
    View details
    High-Volume Salon/Day Spa For Sale
    High-Volume Salon/Day Spa For Sale

    8180 Wehrle Dr, Buffalo, NY 14221

    Contact for pricing
    2,700 sqft

    Established salon/day spa in convenient, high-traffic location.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Main Street Portfolio in Buffalo
    Main Street Portfolio in Buffalo

    1160, 1170 & 1176 Main St, Buffalo, NY 14209

    $6,900,000

    Two interconnected buildings with redevelopment potential in Buffalo's Midtown corridor.

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    Turnkey Medspa Business Opportunity
    Turnkey Medspa Business Opportunity

    3969 Main St, Buffalo, NY 14226

    $100,000

    Established medspa business for sale with equipment and client list.

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 5 Active listings in Buffalo, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office Building with Multiple Exam Rooms
    Medical Office Building with Multiple Exam Rooms

    3101 W Ridge Road, Rochester, NY 14626

    $899,900
    9,674 sqft 0.65 AC lot

    Tenant-occupied medical building with renovated offices, central air, public utilities, and paved parking on 0.65 acres.

    View details
    Fully Leased Nursing Home Building
    Fully Leased Nursing Home Building

    411-415 W 3rd St, Jamestown, NY 14701

    $850,000
    7,140 sqft 0.42 AC lot

    Fully leased, tenant-occupied nursing home building on a high-visibility Jamestown corridor for stabilized commercial use.

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    Freestanding Medical-Friendly Retail Building
    Freestanding Medical-Friendly Retail Building

    3388 Chili Ave, Rochester, NY 14624

    Contact for pricing
    3,373 sqft

    Single-tenant freestanding building offers 66’ frontage on Chili Ave and 20 on-site parking spaces.

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    Mixed-Use Live-Work Building
    Mixed-Use Live-Work Building

    117 S Main St, Jamestown, NY 14701

    Contact for pricing

    Historic live-work property featuring a salon-style lower level and a two-bedroom apartment above with abundant natural light.

    View details

    Off-Market Properties in Buffalo, NY

    Consider similar Off-Market properties in Buffalo, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2497 Delaware Ave
    MEDICAL CLINIC

    2497 Delaware Ave, Buffalo, NY 14216-1712

    $1,595,000
    Estimated value
    7,583 sqft 0.54 AC lot
    View details
    235 North St
    Medical Office Space

    235 North St, Buffalo, NY 14201

    Value Estimation by Request
    19,000 sqft 0.75 AC lot
    View details
    1500 Main St
    HOMES (RETIRED, NURSING)

    1500 Main St, Buffalo, NY 14209-1722

    $1,840,000
    Estimated value
    27,633 sqft 2.01 AC lot
    View details
    3030 Clinton St
    HOMES (RETIRED, NURSING)

    3030 Clinton St, Buffalo, NY 14224-1373

    $8,340,000
    Estimated value
    53,638 sqft 14.65 AC lot
    View details
    700 Ellicott St
    MEDICAL CLINIC

    700 Ellicott St, Buffalo, NY 14203-1102

    $570,000
    Estimated value
    75,255 sqft 1.25 AC lot
    View details
    3600 Harlem Rd
    MEDICAL CLINIC

    3600 Harlem Rd, Buffalo, NY 14215-2012

    $880,000
    Estimated value
    37,496 sqft 1.43 AC lot
    View details
    1542 Maple Rd
    MEDICAL CLINIC

    1542 Maple Rd, Buffalo, NY 14221-3625

    $740,000
    Estimated value
    27,146 sqft 2.82 AC lot
    View details
    1175 Delaware Ave
    MEDICAL CLINIC

    1175 Delaware Ave, Buffalo, NY 14209-1401

    $755,000
    Estimated value
    54,540 sqft 1.16 AC lot
    View details
    135 Evans St
    HOMES (RETIRED, NURSING)

    135 Evans St, Williamsville, NY 14221-5527

    $1,285,000
    Estimated value
    48,206 sqft 5.01 AC lot
    View details
    187 Bryant St
    MEDICAL CLINIC

    187 Bryant St, Buffalo, NY 14222-2065

    $100,000
    Estimated value
    4,410 sqft 0.22 AC lot
    View details
    111 Saint Gregory Ct
    HOMES (RETIRED, NURSING)

    111 Saint Gregory Ct, Williamsville, NY 14221-2633

    $130,000
    Estimated value
    39,117 sqft 4.95 AC lot
    View details
    1597 Elmwood Ave
    MEDICAL CLINIC

    1597 Elmwood Ave, Buffalo, NY 14207-3017

    $2,450,000
    Estimated value
    3,570 sqft 0.46 AC lot
    View details
    142 Forman St
    MEDICAL CLINIC

    142 Forman St, Buffalo, NY 14211-2031

    $70,000
    Estimated value
    6,530 sqft 0.20 AC lot
    View details
    1209 Delaware Ave
    HOMES (RETIRED, NURSING)

    1209 Delaware Ave, Buffalo, NY 14209

    $2,730,000
    Estimated value
    23,320 sqft 0.23 AC lot
    View details
    3456 Delaware Ave
    HOMES (RETIRED, NURSING)

    3456 Delaware Ave, Buffalo, NY 14217-1214

    $735,000
    Estimated value
    30,698 sqft 1.01 AC lot
    View details
    600 Doat St
    HOMES (RETIRED, NURSING)

    600 Doat St, Buffalo, NY 14211-2602

    $975,000
    Estimated value
    123,147 sqft 7.03 AC lot
    View details
    300 Niagara St
    MEDICAL CLINIC

    300 Niagara St, Buffalo, NY 14201-2135

    $830,000
    Estimated value
    23,938 sqft 2.39 AC lot
    View details
    115 Flint Rd
    MEDICAL CLINIC

    115 Flint Rd, Buffalo, NY 14221-3058

    $1,245,000
    Estimated value
    40,194 sqft 2.91 AC lot
    View details
    201 Reist St
    HOMES (RETIRED, NURSING)

    201 Reist St, Buffalo, NY 14221-5387

    $1,445,000
    Estimated value
    111,904 sqft 7.30 AC lot
    View details

    Buffalo, NY Healthcare Properties Market Trends and Statistics

    Explore 72 healthcare properties for sale in Buffalo, NY, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 24,150 square feet of properties for sale, with an estimated market value of $8,379,900.

    Sale prices for medical real estate in Buffalo, NY start at $100,000, averaging $2,094,975, and reaching up to $6,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Medical centers 8
    Spa & wellness properties 7
    Medical space 2
    Rehabilitation centers 1
    Senior Housing / Retirement Homes 1

    Demographics Overview

    Population 586K
    Population Growth (5Y) +6.8%
    Median Household Income $63,542
    College Educated 37.6%

    High-Yield Neighborhoods for Investment

    Identify Buffalo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    14211 $499.9K
    14204 $880K
    14222 $900K

    Taxes & Financing

    Tax Rate (average for all types) 2.47%
    Property Tax per SF $30.36 per SF
    Tax Rate vs County Average 1.02 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Erie County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Erie County

    Retail

    Residential Income

    Property Size Breakdown

    The majority of commercial real estate listings in Buffalo fall within the 10,000 to 25,000 square foot range.

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    Popular Searches in Buffalo, NY

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    Most Searched ZIP Codes in Buffalo, NY

    • 14204
    • 14209
    • 14221
    • 14226

    Featured Buffalo Real Estate Agencies

    Realmo connects you with licensed Buffalo CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    WINDSOR TURNER LLC
    505 Ellicott St Unit 48 Buffalo, NY
    HUNT Commercial
    Buffalo, NY 14203
    www.huntcommercial.com
    Ellicott Development
    Buffalo, NY 14203

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