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    Buffalo, NY Healthcare Properties for Sale

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    Accessible Two-Story Office Building
    Updated: May 21
    Accessible Two-Story Office Building

    1609 Genesee Street, Buffalo, NY 14211

    $499,900
    5,012 sqft 0.43 AC lot
    5,012 SF two‑story brick office building on a 0.43‑acre lot
    Valid Certificate of Occupancy with flexible office and multipurpose layouts
    Full elevator, wheelchair ramp, and wide hallways for accessible circulation
    Four bathrooms, with two on each floor, plus dedicated laundry areas
    Oversized parking lot with 25+ spaces and multiple entry points
    View details
    Church Property with Medical Suite
    Updated: Aug 26, 2025
    Church Property with Medical Suite

    360 Genesee Street, Buffalo, NY 14204

    $880,000
    16,438 sqft 0.87 AC lot
    16,438‑square‑foot church property on a 0.87‑acre site
    Medical suite with waiting room, conference room, and 5 exam rooms
    Three apartments are included within the property
    Sanctuary, kitchen, and dining hall provide varied interior spaces
    Built in 1832; roof, HVAC, bathrooms, kitchens, and equipment have update dates
    View details
    Lower-Level Creative Space
    Lower-Level Creative Space

    1296 Delaware Avenue, Buffalo, NY 14209

    Contact for pricing
    1,000 sqft

    Flexible lower-level premises with access to hotel amenities and owner assistance for tenant improvements.

    View details
    See hot listings in Buffalo

    Scored against comparables nationwide. These are worth a look.

    Scored against comparables nationwide. These are worth a look.

    Cap Rate available after sign in
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    Local Demand available after sign in
    Two-Suite Medical Office Property
    Two-Suite Medical Office Property

    721 Union Rd, West Seneca, NY 14224

    $599,000

    Upper- and lower-level suites support immediate occupancy for office or medical users.

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    Main Street Portfolio in Buffalo
    Main Street Portfolio in Buffalo

    1160, 1170 & 1176 Main St, Buffalo, NY 14209

    $6,900,000

    Two interconnected buildings with redevelopment potential in Buffalo's Midtown corridor.

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 5 Active listings in Buffalo, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 67 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Three-Story Mixed-Use Brick Building
    Three-Story Mixed-Use Brick Building

    33 Church Street, Fredonia, NY 14063

    $999,900
    11,273 sqft 0.17 AC lot

    Downtown commercial property with elevator access, a separate deli building, and established business occupancy.

    View details
    Three-Story Mixed-Use Brick Building
    Three-Story Mixed-Use Brick Building

    Fredonia, NY 14063

    $999,900
    11,273 sqft

    Historic commercial building with elevator access, multiple office suites, and existing occupancy across three levels.

    View details
    Turn-Key Salon and Wellness Space
    Turn-Key Salon and Wellness Space

    133 Pine St, Hamburg, NY 14075

    Contact for pricing
    939 sqft

    Well-maintained commercial space with four private stylist stations, wash areas, and reception/waiting area.

    View details
    Lakefront Mixed-Use Property
    Lakefront Mixed-Use Property

    4904 Lake Shore Road, Hamburg, NY 14075

    $524,900

    NC-zoned property with a primary residence, separate lakeside building, and owned Lake Erie frontage.

    View details

    Off-Market Properties in Buffalo, NY

    Consider similar Off-Market properties in Buffalo, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    2497 Delaware Ave
    MEDICAL CLINIC

    2497 Delaware Ave, Buffalo, NY 14216-1712

    Estimated value:
    $1,595,000
    7,583 sqft 0.54 AC lot
    View details
    235 North St
    Medical Office Space

    235 North St, Buffalo, NY 14201

    Estimated value: by Request
    19,000 sqft 0.75 AC lot
    View details
    1500 Main St
    HOMES (RETIRED, NURSING)

    1500 Main St, Buffalo, NY 14209-1722

    Estimated value:
    $1,840,000
    27,633 sqft 2.01 AC lot
    View details
    3030 Clinton St
    HOMES (RETIRED, NURSING)

    3030 Clinton St, Buffalo, NY 14224-1373

    Estimated value:
    $8,340,000
    53,638 sqft 14.65 AC lot
    View details
    700 Ellicott St
    MEDICAL CLINIC

    700 Ellicott St, Buffalo, NY 14203-1102

    Estimated value:
    $570,000
    75,255 sqft 1.25 AC lot
    View details
    3600 Harlem Rd
    MEDICAL CLINIC

    3600 Harlem Rd, Buffalo, NY 14215-2012

    Estimated value:
    $880,000
    37,496 sqft 1.43 AC lot
    View details
    1542 Maple Rd
    MEDICAL CLINIC

    1542 Maple Rd, Buffalo, NY 14221-3625

    Estimated value:
    $740,000
    27,146 sqft 2.82 AC lot
    View details
    1175 Delaware Ave
    MEDICAL CLINIC

    1175 Delaware Ave, Buffalo, NY 14209-1401

    Estimated value:
    $755,000
    54,540 sqft 1.16 AC lot
    View details
    135 Evans St
    HOMES (RETIRED, NURSING)

    135 Evans St, Williamsville, NY 14221-5527

    Estimated value:
    $1,285,000
    48,206 sqft 5.01 AC lot
    View details
    187 Bryant St
    MEDICAL CLINIC

    187 Bryant St, Buffalo, NY 14222-2065

    Estimated value:
    $100,000
    4,410 sqft 0.22 AC lot
    View details
    111 Saint Gregory Ct
    HOMES (RETIRED, NURSING)

    111 Saint Gregory Ct, Williamsville, NY 14221-2633

    Estimated value:
    $130,000
    39,117 sqft 4.95 AC lot
    View details
    1597 Elmwood Ave
    MEDICAL CLINIC

    1597 Elmwood Ave, Buffalo, NY 14207-3017

    Estimated value:
    $2,450,000
    3,570 sqft 0.46 AC lot
    View details
    142 Forman St
    MEDICAL CLINIC

    142 Forman St, Buffalo, NY 14211-2031

    Estimated value:
    $70,000
    6,530 sqft 0.20 AC lot
    View details
    1209 Delaware Ave
    HOMES (RETIRED, NURSING)

    1209 Delaware Ave, Buffalo, NY 14209

    Estimated value:
    $2,730,000
    23,320 sqft 0.23 AC lot
    View details
    3456 Delaware Ave
    HOMES (RETIRED, NURSING)

    3456 Delaware Ave, Buffalo, NY 14217-1214

    Estimated value:
    $735,000
    30,698 sqft 1.01 AC lot
    View details
    600 Doat St
    HOMES (RETIRED, NURSING)

    600 Doat St, Buffalo, NY 14211-2602

    Estimated value:
    $975,000
    123,147 sqft 7.03 AC lot
    View details
    300 Niagara St
    MEDICAL CLINIC

    300 Niagara St, Buffalo, NY 14201-2135

    Estimated value:
    $830,000
    23,938 sqft 2.39 AC lot
    View details
    115 Flint Rd
    MEDICAL CLINIC

    115 Flint Rd, Buffalo, NY 14221-3058

    Estimated value:
    $1,245,000
    40,194 sqft 2.91 AC lot
    View details
    201 Reist St
    HOMES (RETIRED, NURSING)

    201 Reist St, Buffalo, NY 14221-5387

    Estimated value:
    $1,445,000
    111,904 sqft 7.30 AC lot
    View details

    Buffalo, NY Healthcare Properties Market Trends and Statistics

    Explore 72 healthcare properties for sale in Buffalo, NY, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 22,450 square feet of properties for sale, with an estimated market value of $8,878,900.

    Sale prices for medical real estate in Buffalo, NY start at $499,900, averaging $2,219,725, and reaching up to $6,900,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Medical centers 5
    Spa & wellness properties 5
    Rehabilitation centers 1
    Senior Housing / Retirement Homes 1

    Demographics Overview

    Population 586K
    Population Growth (5Y) +6.8%
    Median Household Income $63,542
    College Educated 37.6%

    High-Yield Neighborhoods for Investment

    Identify Buffalo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    14211 $499.9K
    14204 $880K
    14209 $3.5M

    Taxes & Financing

    Tax Rate (average for all types) 2.47%
    Property Tax per SF $30.36 per SF
    Tax Rate vs County Average 1.02 pp below county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Erie County

    New Delisted

    Total CRE Inventory on Market (SF)

    Property Size Breakdown

    The majority of commercial real estate listings in Buffalo fall within the 10,000 to 25,000 square foot range.

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