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    Florence County, SC Medical Office Space for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    Remodeled Commercial Building Near Downtown
    $320,000
    2,165 SF
    Remodeled Commercial Building Near Downtown

    910 W Evans st, Florence, SC 29501

    Turnkey commercial property in prime location with excellent visibility.
    • Completely remodeled/rebuilt from the ground up with new roof, HVAC, electrical, and plumbing.
    • Prime location minutes from downtown Florence with excellent visibility and access.
    • Turnkey property suitable for a medical office, salon, law firm, or small business.
    • Five spacious rooms that can serve as private offices or treatment spaces.
    • Modern kitchen with brand‑new cabinets and granite countertops.
    Updated: Apr 24
    View details
    McLeod Physician Associates For Sale
    $1,384,320
    2,666 SF
    McLeod Physician Associates For Sale

    1540 American Dr, Florence, SC

    2,666 SF medical office in Florence, SC for sale.
    • Secure Investment
    • Triple Net (NNN) Lease – Landlord Has Limited Responsibilities
    • Tenant Recently Extended Lease For an Additional 5 Years, showing long‑term commitment to the site
    • Located at 1540 American Drive in Florence, SC
    • 2,666 SF McLeod Physician Associates
    Updated: Jul 24, 2025
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    Medical Office Building Near MUSC
    $2,200,000
    7,950 SF
    Medical Office Building Near MUSC

    Medical office building near MUSC campus with ample parking.

    1929 Mountain Laurel Court, Florence, SC

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    Timmonsville Medical Office Building
    $125,000
    1,968 SF
    Timmonsville Medical Office Building

    Well-maintained 2,000 SF building suitable for various office uses.

    101 Market St, Timmonsville, SC 29161

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 4 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 68 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land on Highway 501
    $225,000
    1.40 Acres
    Commercial Land on Highway 501

    1.35 acre commercial land with 200 feet on Hwy 501.

    College Park Rd. lot: 1 & 2, Conway, SC 29527

    View details
    Hamlet, NC Land Opportunity
    $285,000
    10.75 Acres
    Hamlet, NC Land Opportunity

    10.75 acre tract zoned OI near Hamlet, NC.

    Wiregrass Road, Hamlet, NC 28345

    View details
    Commercial Land Near Conway Medical
    $375,000
    0.78 Acres
    Commercial Land Near Conway Medical

    Cleared commercial lot with approved medical office plans.

    Professional Park Dr. lot: 11, Conway, SC 29526

    View details
    Rockingham Land Near FirstHealth
    $50,000
    0.50 Acres
    Rockingham Land Near FirstHealth

    0.5 acre lot ideal for medical or office use.

    105 Medical Circle lot: 2, Rockingham, NC 28379

    View details

    Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    316 Mcqueen St
    MEDICAL BUILDING
    1,470 SF Lot: 0.18 Acres
    Value Estimation by Request

    316 Mcqueen St, Florence, SC 29501-4723

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    1530 Mclure Ct
    MEDICAL BUILDING
    10,148 SF Lot: 1.22 Acres
    Value Estimation by Request

    1530 Mclure Ct, Florence, SC 29505-6174

    View details
    130 Acline St
    MEDICAL BUILDING
    2,052 SF Lot: 0.22 Acres
    Value Estimation by Request

    130 Acline St, Lake City, SC 29560-2633

    View details
    262 Cheves St
    DENTAL BUILDING
    1,460 SF Lot: 0.52 Acres
    Value Estimation by Request

    262 Cheves St, Florence, SC 29501-4404

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    411 Dargan St
    MEDICAL BUILDING
    5,187 SF
    Value Estimation by Request

    411 Dargan St, Florence, SC 29506-2541

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    331 Elizabeth Anne Ct
    MEDICAL BUILDING
    7,920 SF Lot: 1.10 Acres
    Estimated value
    $1,905,000

    331 Elizabeth Anne Ct, Lake City, SC 29560-2488

    View details
    406 Church St
    MEDICAL BUILDING
    8,160 SF Lot: 0.29 Acres
    Estimated value
    $1,445,000

    406 Church St, Florence, SC 29506-3000

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    1525 Heritage Ln
    DENTAL BUILDING
    1,736 SF Lot: 0.30 Acres
    Estimated value
    $535,000

    1525 Heritage Ln, Florence, SC 29505-3141

    View details
    1260 Celebration Blvd
    MEDICAL BUILDING
    3,953 SF Lot: 0.63 Acres
    Value Estimation by Request

    1260 Celebration Blvd, Florence, SC 29501-5498

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    325 Mercy St
    MEDICAL BUILDING
    5,461 SF Lot: 0.64 Acres
    Value Estimation by Request

    325 Mercy St, Lake City, SC 29560-2331

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    115 Matthews Rd
    MEDICAL BUILDING
    1,588 SF Lot: 0.29 Acres
    Value Estimation by Request

    115 Matthews Rd, Lake City, SC 29560-2309

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    312 Mcqueen St
    MEDICAL BUILDING
    3,225 SF Lot: 0.33 Acres
    Value Estimation by Request

    312 Mcqueen St, Florence, SC 29501-4723

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    1498 Freedom Blvd
    MEDICAL BUILDING
    3,562 SF Lot: 0.92 Acres
    Estimated value
    $710,000

    1498 Freedom Blvd, Florence, SC 29505-6077

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    619 Dargan St
    MEDICAL BUILDING
    3,456 SF Lot: 0.65 Acres
    Value Estimation by Request

    619 Dargan St, Florence, SC 29506-2555

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    701 Dargan St
    MEDICAL BUILDING
    1,050 SF Lot: 0.19 Acres
    Value Estimation by Request

    701 Dargan St, Florence, SC 29506-2560

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    276 Ron Mcnair Blvd
    MEDICAL BUILDING
    8,990 SF Lot: 2.16 Acres
    Estimated value
    $845,000

    276 Ron Mcnair Blvd, Lake City, SC 29560-2462

    View details
    1507 Heritage Ln
    DENTAL BUILDING
    4,800 SF Lot: 0.61 Acres
    Value Estimation by Request

    1507 Heritage Ln, Florence, SC 29505-3141

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    517 Palmetto St
    DENTAL BUILDING
    2,797 SF Lot: 0.26 Acres
    Value Estimation by Request

    517 Palmetto St, Florence, SC 29501-4427

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    2200 Irby St
    MEDICAL BUILDING
    5,996 SF Lot: 1.03 Acres
    Estimated value
    $3,190,000

    2200 Irby St, Florence, SC 29505-3423

    View details
    2410 Hoffmeyer Rd
    MEDICAL BUILDING
    4,118 SF Lot: 1.00 Acre
    Estimated value
    $2,415,000

    2410 Hoffmeyer Rd, Florence, SC 29501-7311

    View details

    Florence County, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 72 medical office space for sale in Florence County, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 14,749 square feet of properties for sale, with an estimated market value of $4,029,320.

    Sale prices for medical spaces in Florence County, SC start at $125,000, averaging $1,007,330, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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