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    Beaufort County, SC Medical Office Space for Sale

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    Columbia, SC Hilton Head Island, SC Myrtle Beach, SC Greenville, SC Spartanburg, SC Charleston, SC Anderson, SC Aiken, SC
    16 properties
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    Remodeled Two-Level Wellness Property
    Updated: Sep 10
    Remodeled Two-Level Wellness Property

    16 Shelter Cove Lane, Hilton Head Island, SC 29928

    $1,999,000
    Remodeled standalone building with two levels
    Located at a signalized intersection along Highway 278
    Near the entrance to Shelter Cove Harbour & Marina and Palmetto Dunes
    Steps from Shelter Cove Town Centre
    Suitable for office, retail, medical, professional, and other commercial uses
    View details
    Leased Medical Office Space
    Updated: Oct 7
    Leased Medical Office Space

    53 Persimmons Street, Bluffton, SC 29910

    $1,395,000
    3,500‑square‑foot medical office property
    Fully leased to a long‑term medical tenant
    8.29% cap rate
    3% annual rent increases
    Near Bluffton Parkway
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    Medical Office with CT Scanner
    Medical Office with CT Scanner

    14 Oak Forest Road, Bluffton, SC 29910

    $1,600,000

    Renovated in 2024, the suite combines imaging equipment with exam, laboratory, and patient-support areas.

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    Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
    Medical Office Suites
    Medical Office Suites

    23 Main Street, Suite 101, Hilton Head Island, SC 29926

    $499,000
    1,500 sqft

    Ground-floor space is divided into two suites, with one currently leased and the other vacant.

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    Built-Out Medical Office Space
    Built-Out Medical Office Space

    53 Persimmons Street, Bluffton, SC 29910

    Contact for pricing

    Existing professional improvements support medical, healthcare, and other office uses with limited additional build-out needs.

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    Stand Alone Medical Office Building
    Stand Alone Medical Office Building

    4101 Main St, Suite E & F, Hilton Head Island, SC 29926

    $1,348,000
    3,600 sqft

    Stand-alone medical building on Hilton Head Island, ready for occupancy.

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    Built-Out Medical Office Space
    Built-Out Medical Office Space

    53 Persimmons Street STE 105, Bluffton, SC 29910

    Contact for pricing
    3,445 sqft

    Existing medical-office improvements support healthcare and professional occupancy, subject to the current lease and landlord approval.

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    Highway 278 Frontage Office Building
    Highway 278 Frontage Office Building

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    8,800 sqft

    Class A office/medical building on Highway 278 in Bluffton.

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    Medical Office Suite Near Hospital
    Medical Office Suite Near Hospital

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

    Contact for pricing
    750 sqft

    Ground floor medical office suite near Hilton Head Hospital.

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    Medical Office Suite with CT Scanner
    Medical Office Suite with CT Scanner

    D-14 Oak Forest Road, Bluffton, SC 29910

    $1,600,000

    Clinical space combines exam rooms with laboratory, reception, and patient waiting areas.

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    Medical Office Suite Near Hospital
    Medical Office Suite Near Hospital

    23 Main Street, Suite 101-A, Hilton Head Island, SC 29926

    Contact for pricing
    1,500 sqft

    Ground floor medical office suite available near Hilton Head Hospital.

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    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    23 Main St, Hilton Head Island, SC 29926

    Contact for pricing
    1,213 sqft

    Medical office suite near Hilton Head Hospital with reception, waiting area, restroom, and multiple exam rooms.

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    Bluffton Office/Medical Building For Sale
    Bluffton Office/Medical Building For Sale

    5 Buck Island Rd, Bluffton, SC 29910

    Contact for pricing
    17,525 sqft

    Class A office/medical building fronting Highway 278 in Bluffton.

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    Hilton Head Office/Medical Space
    Hilton Head Office/Medical Space

    23 Main Street, Suite 303, Hilton Head Island, SC 29926

    $375,000

    Office/Medical space for sale near Hilton Head Hospital.

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    Medical Office Suites For Sale
    Medical Office Suites For Sale

    25 Hospital Center Boulevard, Hilton Head Island, SC 29926

    Contact for pricing

    Medical office suites available in prestigious Hilton Head medical complex.

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    Medical Office Suites Near Hospital
    Medical Office Suites Near Hospital

    25 Hospital Center Boulevard, Hilton Head Island, SC 29926

    Contact for pricing

    Medical office suites for lease adjacent to Hilton Head Hospital.

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    16 active listings match your search: Medical Office for sale in Beaufort County, SC. Based on your search, we've also compiled 56 Potential Opportunities for your consideration: 56 off-market properties to explore as potential leads.

    Off-Market Properties in Beaufort County, SC

    Consider similar Off-Market properties in Beaufort County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    65 Sams Pt Rd
    DENTAL BUILDING

    65 Sams Pt Rd, Beaufort, SC 29907-2010

    Estimated value:
    $570,000
    1,244 sqft 0.04 AC lot
    View details
    35 Bill Fries Dr
    MEDICAL BUILDING

    35 Bill Fries Dr, Hilton Head Island, SC 29926-2730

    Estimated value:
    $335,000
    2,330 sqft 1.00 AC lot
    View details
    35 Bill Fries Dr
    MEDICAL BUILDING

    35 Bill Fries Dr, Hilton Head Island, SC 29926-2730

    Estimated value:
    $245,000
    1,986 sqft 1.00 AC lot
    View details
    33 Marshellen Dr
    MEDICAL BUILDING

    33 Marshellen Dr, Beaufort, SC 29902-6900

    Estimated value:
    $200,000
    3,369 sqft 0.08 AC lot
    View details
    845 William Hilton Pkwy
    MEDICAL BUILDING

    845 William Hilton Pkwy, Hilton Head Island, SC 29928-3404

    Estimated value:
    $430,000
    4,322 sqft 0.96 AC lot
    View details
    13 Marshellen Dr
    MEDICAL BUILDING

    13 Marshellen Dr, Beaufort, SC 29902-6900

    Estimated value:
    $480,000
    3,369 sqft 0.08 AC lot
    View details
    35 Pondberry St
    MEDICAL BUILDING

    35 Pondberry St, Bluffton, SC 29910-9724

    Estimated value:
    $3,040,000
    4,260 sqft 1.43 AC lot
    View details
    10 Marshellen Dr
    MEDICAL BUILDING

    10 Marshellen Dr, Beaufort, SC 29902-6900

    Estimated value:
    $325,000
    3,369 sqft 0.08 AC lot
    View details

    Beaufort County, SC Medical Office Space Market Trends and Statistics

    Explore 72 medical office space for sale in Beaufort County, SC, showcased through 16 active listings on our real estate platform. These investment opportunities span a total of 38,333 square feet of properties for sale, with an estimated market value of $8,816,000.

    Sale prices for medical spaces in Beaufort County, SC start at $375,000, averaging $1,259,428, and reaching up to $1,999,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Beaufort County Real Estate Agencies

    Realmo connects you with licensed Beaufort County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Daniel Ravenel Sotheby's International Realty
    6 Promenade Street, Suite 1001 Bluffton, SC 29910
    Phone: (843) 723-7150
    www.danielravenelsir.com/
    Hilton Head Real Estate Partners
    1000 Main Street, Suite 100D Hilton Head Island, SC 29926
    Phone: (843) 301-5825
    www.hiltonheadrealestatepartners.com
    Sea Pines Real Estate at The Beach Club
    P. O. Box 3191, 87 N. Sea Pines Drive Hilton Head Island, SC 29928
    Phone: (843) 816-2672
    www.beachclubrealestate.com
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