Medical Premises

Seneca, SC Medical Office Space for Sale

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Medical Office Building
Updated: Aug 26
Medical Office Building

685 S. Oak Street, Seneca, SC 29678

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4,200 sqft
4,200 SF medical office building
Five‑year lease renewal option in March 2026
2% annual rent bumps
685 S. Oak Street, Seneca, South Carolina
Access to downtown Seneca, Clemson, and US‑123
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Scored against comparables nationwide. These are worth a look.

Scored against comparables nationwide. These are worth a look.

Cap Rate available after sign in
Est. NOI available after sign in
Local Demand available after sign in
Based on your search, we've compiled 69 Potential Opportunities for your consideration. Besides 1 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 63 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Medical Office Building For Sale
Medical Office Building For Sale

102 Buford Avenue, Anderson, SC 29621

$1,050,000
10,405 sqft

Multi-tenant medical office building near AnMed campuses with development potential.

View details
Medical Office with Consultation Rooms
Medical Office with Consultation Rooms

436 Warwoman Road, Clayton, GA 30525

$385,000
2,700 sqft 0.43 AC lot

Configured for patient-facing operations with reception, private rooms, kitchen, and separate front and rear bathrooms.

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Dental Office Space
Dental Office Space

436 Warwoman Road, Clayton, GA 30525

$385,000
2,700 sqft

Dental office layout includes a large waiting room, multiple consultation rooms, and front and back restrooms.

View details
Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

400 N Fant Street, Anderson, SC 29621

$185,000

Front suite with a medical layout, reception, waiting area, private offices, and separate exterior entrances.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Land in Greenville, SC
Prime Land in Greenville, SC

3900 Highway 153, Greenville, SC 29611

$1,800,000
10.91 AC lot

11+/- acre property ideal for development in a growing corridor.

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Off-Market Properties in Seneca, SC

Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

203 Central Park Ln
MEDICAL BUILDING

203 Central Park Ln, Seneca, SC 29678-1156

Estimated value:
$520,000
4,578 sqft 0.11 AC lot
View details
Seneca, SC 29678
MEDICAL BUILDING

Seneca, SC 29678

Estimated value:
$385,000
2,929 sqft 0.27 AC lot
View details
693 Oak St
MEDICAL BUILDING

693 Oak St, Seneca, SC 29678-3827

Estimated value:
$510,000
4,900 sqft 1.00 AC lot
View details
959 By Pass 123rd A Ste A
MEDICAL BUILDING

959 By Pass 123rd A Ste A, Seneca, SC 29678-4706

Estimated value:
$55,000
13,440 sqft 1.52 AC lot
View details
2 Leas Courtyard Dr
MEDICAL BUILDING

2 Leas Courtyard Dr, Seneca, SC 29672-6660

Estimated value:
$195,000
3,320 sqft 0.14 AC lot
View details
11 Professionals Cir
DENTAL BUILDING

11 Professionals Cir, Seneca, SC 29678-2669

Estimated value:
$340,000
2,848 sqft 0.16 AC lot
View details
10626 Clemson Blvd
MEDICAL BUILDING

10626 Clemson Blvd, Seneca, SC 29678-4526

Estimated value:
$2,150,000
13,342 sqft 0.25 AC lot
View details
15575 Wls Hwy
MEDICAL BUILDING

15575 Wls Hwy, Seneca, SC 29678-1664

Estimated value:
$905,000
9,944 sqft 1.89 AC lot
View details
241 Stork Way
DENTAL BUILDING

241 Stork Way, Seneca, SC 29678-1039

Estimated value:
$710,000
4,458 sqft 0.85 AC lot
View details
215 Stork Way
MEDICAL BUILDING

215 Stork Way, Seneca, SC 29678-1039

Estimated value:
$960,000
6,400 sqft 2.11 AC lot
View details
101 Beverly Dr
DENTAL BUILDING

101 Beverly Dr, Seneca, SC 29672-2487

Estimated value:
$1,170,000
3,945 sqft 1.93 AC lot
View details
10110 Clemson Blvd
MEDICAL BUILDING

10110 Clemson Blvd, Seneca, SC 29678-0812

Estimated value:
$265,000
6,232 sqft 2.20 AC lot
View details
112 Surgical Blvd
MEDICAL BUILDING

112 Surgical Blvd, Seneca, SC 29672-6654

Estimated value:
$225,000
2,295 sqft 0.03 AC lot
View details
103 Carter Park Dr
MEDICAL BUILDING

103 Carter Park Dr, Seneca, SC 29678-1152

Estimated value:
$2,900,000
6,056 sqft 0.14 AC lot
View details
105 Carter Park Dr
MEDICAL BUILDING

105 Carter Park Dr, Seneca, SC 29678-1152

Estimated value:
$2,900,000
6,056 sqft 0.14 AC lot
View details
1059 By Pass 123
MEDICAL BUILDING

1059 By Pass 123, Seneca, SC 29678-4762

Estimated value:
$260,000
7,100 sqft 0.93 AC lot
View details
4 Cmns Blvd
DENTAL BUILDING

4 Cmns Blvd, Seneca, SC 29678-2666

Estimated value:
$235,000
1,595 sqft 0.13 AC lot
View details
Seneca, SC 29678
DENTAL BUILDING

Seneca, SC 29678

Estimated value:
$295,000
2,468 sqft 0.74 AC lot
View details
16 Cmns Blvd
MEDICAL BUILDING

16 Cmns Blvd, Seneca, SC 29678-2666

Estimated value:
$210,000
2,288 sqft 0.26 AC lot
View details
135 Professional Park Dr
MEDICAL BUILDING

135 Professional Park Dr, Seneca, SC 29678-2558

Estimated value:
$935,000
3,954 sqft 0.97 AC lot
View details
309 Wn 2nd St
MEDICAL BUILDING

309 Wn 2nd St, Seneca, SC 29678-3111

Estimated value:
$255,000
2,216 sqft 0.46 AC lot
View details
11092 Radio Sta Rd
MEDICAL BUILDING

11092 Radio Sta Rd, Seneca, SC 29678-1142

Estimated value:
$170,000
1,968 sqft 1.34 AC lot
View details
685 Oak St
MEDICAL BUILDING

685 Oak St, Seneca, SC 29678-3827

Estimated value:
$300,000
4,291 sqft 0.50 AC lot
View details

Seneca, SC Medical Office Space Market Trends and Statistics

Explore 64 medical office space for sale in Seneca, SC on our real estate platform. These investment opportunities span a total of 4,200 square feet of properties for sale.

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Map

Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 12
Office buildings 5
Medical Office Space 2

Demographics Overview

Population 36K
Population Growth (5Y) +2.7%
Median Household Income $62,735
College Educated 31.9%

Listings Trend

New vs delisted commercial listings in Oconee County

New Delisted

Total CRE Inventory on Market (SF)

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