Medical Premises

Bluffton, SC Medical Office Space for Sale

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Hilton Head Island, SC Beaufort, SC Westminster, SC Ridgeland, SC Hardeeville, SC Port Royal, SC Saint Helena Island, SC
6 properties
Leased Medical Office Space
Updated: Oct 7
Leased Medical Office Space

53 Persimmons Street, Bluffton, SC 29910

$1,395,000
3,500‑square‑foot medical office property
Fully leased to a long‑term medical tenant
8.29% cap rate
3% annual rent increases
Near Bluffton Parkway
View details
Medical Office with CT Scanner
Updated: Oct 5
Medical Office with CT Scanner

14 Oak Forest Road, Bluffton, SC 29910

$1,600,000
CT scan room and machine are included in the sale
Renovated in 2024
7 exam rooms, plus a physician’s office
Includes a lab, nurses station, reception, and waiting areas
Three bathrooms and extensive storage
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Built-Out Medical Office Space
Built-Out Medical Office Space

53 Persimmons Street, Bluffton, SC 29910

Contact for pricing

Existing professional improvements support medical, healthcare, and other office uses with limited additional build-out needs.

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Built-Out Medical Office Space
Built-Out Medical Office Space

53 Persimmons Street STE 105, Bluffton, SC 29910

Contact for pricing
3,445 sqft

Existing medical-office improvements support healthcare and professional occupancy, subject to the current lease and landlord approval.

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Highway 278 Frontage Office Building
Highway 278 Frontage Office Building

5 Buck Island Rd, Bluffton, SC 29910

Contact for pricing
8,800 sqft

Class A office/medical building on Highway 278 in Bluffton.

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Bluffton Office/Medical Building For Sale
Bluffton Office/Medical Building For Sale

5 Buck Island Rd, Bluffton, SC 29910

Contact for pricing
17,525 sqft

Class A office/medical building fronting Highway 278 in Bluffton.

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Based on your search, we've compiled 34 Potential Opportunities for your consideration. Besides 6 Active listings in Bluffton, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

NNN Corner Property
NNN Corner Property

22 W Oglethorpe Avenue # H, Savannah, GA 31401

$599,999
1,070 sqft

A triple net lease extends through May 2027, with annual CPI-based increases and an established physical therapy tenant.

View details
Leased Medical Office Space
Leased Medical Office Space

22 W Oglethorpe Avenue, Savannah, GA 31401

$599,999
1,070 sqft 0.02 AC lot

Brick medical office property with an existing triple-net lease and annual CPI-based rent increases.

View details
Stand Alone Medical Office Building
Stand Alone Medical Office Building

4101 Main St, Suite E & F, Hilton Head Island, SC 29926

$1,348,000
3,600 sqft

Stand-alone medical building on Hilton Head Island, ready for occupancy.

View details
Medical Office Suites Near Hospital
Medical Office Suites Near Hospital

25 Hospital Center Boulevard, Hilton Head Island, SC 29926

Contact for pricing

Medical office suites for lease adjacent to Hilton Head Hospital.

View details

Off-Market Properties in Bluffton, SC

Consider similar Off-Market properties in Bluffton, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

35 Pondberry St
MEDICAL BUILDING

35 Pondberry St, Bluffton, SC 29910-9724

Estimated value:
$3,040,000
4,260 sqft 1.43 AC lot
View details
3 Plantation Park Dr
MEDICAL BUILDING

3 Plantation Park Dr, Bluffton, SC 29910-6035

Estimated value:
$1,440,000
4,120 sqft 1.18 AC lot
View details
64 Bluffton Rd
MEDICAL BUILDING

64 Bluffton Rd, Bluffton, SC 29910-7621

Estimated value:
$3,475,000
6,025 sqft 0.90 AC lot
View details
100 Buckwalter Pl Blvd
MEDICAL BUILDING

100 Buckwalter Pl Blvd, Bluffton, SC 29910-5022

Estimated value:
$13,570,000
40,847 sqft 3.79 AC lot
View details
4818 Bluffton Pkwy
MEDICAL BUILDING

4818 Bluffton Pkwy, Bluffton, SC 29910-4602

Estimated value:
$250,000
5,578 sqft 0.19 AC lot
View details
Bluffton Pkwy
MEDICAL BUILDING

Bluffton Pkwy, Bluffton, SC 29910

Estimated value: by Request
6,337 sqft 0.21 AC lot
View details
110 Buckwalter Pl Blvd
MEDICAL BUILDING

110 Buckwalter Pl Blvd, Bluffton, SC 29910-5154

Estimated value: by Request
3,828 sqft 1.32 AC lot
View details
Bluffton, SC 29910
MEDICAL BUILDING

Bluffton, SC 29910

Estimated value: by Request
3,648 sqft 0.06 AC lot
View details
81 Baylor Dr
MEDICAL BUILDING

81 Baylor Dr, Bluffton, SC 29910

Estimated value: by Request
61,102 sqft 12.20 AC lot
View details
31 Innovation Dr
MEDICAL BUILDING

31 Innovation Dr, Bluffton, SC 29910-5159

Estimated value:
$1,120,000
6,320 sqft 0.08 AC lot
View details
162 Bluffton Rd
MEDICAL BUILDING

162 Bluffton Rd, Bluffton, SC 29910-6340

Estimated value: by Request
5,040 sqft 0.89 AC lot
View details
168 Bluffton Rd
MEDICAL BUILDING

168 Bluffton Rd, Bluffton, SC 29910-6248

Estimated value: by Request
2,376 sqft 0.38 AC lot
View details
164 Bluffton Rd
MEDICAL BUILDING

164 Bluffton Rd, Bluffton, SC 29910-6248

Estimated value: by Request
3,230 sqft 0.38 AC lot
View details
350 Fording Is Rd
MEDICAL BUILDING

350 Fording Is Rd, Bluffton, SC 29910-5168

Estimated value: by Request
15,991 sqft 2.03 AC lot
View details
101 Okatie Ctr S Blvd
MEDICAL BUILDING

101 Okatie Ctr S Blvd, Bluffton, SC 29909-7547

Estimated value: by Request
6,565 sqft 1.87 AC lot
View details
Buckwalter Pkwy
MEDICAL BUILDING

Buckwalter Pkwy, Bluffton, SC 29910

Estimated value: by Request
2,992 sqft 0.71 AC lot
View details
4818 Bluffton Pkwy
MEDICAL BUILDING

4818 Bluffton Pkwy, Bluffton, SC 29910-4602

Estimated value: by Request
8,664 sqft 0.28 AC lot
View details
7 Palmetto Way
MEDICAL BUILDING

7 Palmetto Way, Bluffton, SC 29910-9696

Estimated value:
$665,000
5,490 sqft 0.05 AC lot
View details

Bluffton, SC Medical Office Space Market Trends and Statistics

Explore 30 medical office space for sale in Bluffton, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 29,770 square feet of properties for sale, with an estimated market value of $2,995,000.

Sale prices for medical spaces in Bluffton, SC start at $1,395,000, averaging $1,497,500, and reaching up to $1,600,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 17
Medical Office Space 13
Office buildings 9

Demographics Overview

Population 74K
Population Growth (5Y) +24.7%
Median Household Income $94,589
College Educated 66.8%

High-Yield Neighborhoods for Investment

Identify Bluffton submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
Okatie - 29909 $950K

Taxes & Financing

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Beaufort County

New Delisted

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