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    Charleston, SC Medical Office Space for Sale

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    Wando, SC Mount Pleasant, SC Huger, SC
    Charleston Medical Property Investment
    $1,895,000
    Charleston Medical Property Investment

    2039 Savannah Highway, Charleston, SC 29407

    Thriving medical property in Charleston, SC with favorable lease terms.
    • High Cap Rate: Attractive 6.65% Cap Rate ensures a strong return on investment.
    • Stable Income: 100% occupancy with a favorable Triple Net Lease (NNN) provides consistent cash flow.
    • Favorable Lease Terms: 5‑year lease term with a 5‑year renewal option and 3% annual rent increases offer long‑term growth potential.
    • Strategic Location: Prime location at the intersection of Savannah Highway and I‑526 in a high‑traffic commercial corridor with excellent accessibility.
    • Recent Renovation: Renovated in 2019, the building is modern and well‑maintained.
    Updated: Jun 30, 2025
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    Free-Standing Office Building
    $895,000
    5,000 SF
    Free-Standing Office Building

    4476 Leeds Place West, Charleston, SC 29405

    A flexible office layout offers private offices, open bullpen space, and exam-ready rooms for medical or legal use.
    • 5,000 SF free‑standing office building built in 1999
    • Layout offers 3,800 SF in the front and 1,200 SF in the back
    • Includes private offices/exam rooms, open bullpen area, conference room, break room, and reception area
    • Suites can be used individually or together
    • Flexible space suited for general office, medical office, or legal office use
    Updated: Jun 2
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    Freestanding Mixed-Use Retail/Office
    $500,000
    1,330 SF
    Freestanding Mixed-Use Retail/Office

    Freestanding two-story building with flexible office, medical office, or retail use.

    154 Cannon Street, Charleston, SC 29403

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    Northbridge Executive Park Investment
    $15,968,500
    54,500 SF
    Northbridge Executive Park Investment

    Two-building office campus near Ashley Landing redevelopment.

    1176-1180 Sam Rittenberg Blvd, Charleston, SC

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    Prime Land in West Ashley
    $1,800,000
    6.32 Acres
    Prime Land in West Ashley

    6.32 acres in Charleston, SC, ideal for development.

    Henry Tecklenburg Dr, Charleston, SC 29414

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    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 5 Active listings in Charleston, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 4 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Former Daycare Near Navy Yard
    $2,300,000
    12,895 SF
    Former Daycare Near Navy Yard

    12,895 SF former daycare near new Navy Yard project.

    1910 McMillan Avenue, North Charleston, SC 29405

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    North Charleston Medical Office Building
    $1,500,000
    4,345 SF
    North Charleston Medical Office Building

    Commercial property suitable for medical or professional office use.

    3800 Faber Place Drive, North Charleston, SC 29405

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    Nexton Mixed-Use Development Opportunity
    $18,000,000
    30,000 SF
    Nexton Mixed-Use Development Opportunity

    Mixed-use property for sale or lease in Nexton, Summerville.

    1227 Nexton Pkwy, Summerville, SC 29486

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    Medical Office Space Available
    $2,050,000
    2,423 SF
    Medical Office Space Available

    Professional office suites for lease in thriving medical complex.

    85 Springview Ln, Summerville, SC

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Beaufort Land for Sale
    $459,000
    7.32 Acres
    Beaufort Land for Sale

    7.32 acre commercial land in Beaufort, South Carolina.

    Goethe Hill Road lot: 3, Beaufort, SC 29906

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    Prime Commercial Land Pawleys Island
    $450,000
    0.52 Acres
    Prime Commercial Land Pawleys Island

    Commercial real estate near Highway 17 and Litchfield By The Sea.

    Portion Wall St., Pawleys Island, SC 29585

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    Commercial Land in Murrells Inlet
    $750,000
    0.89 Acres
    Commercial Land in Murrells Inlet

    Commercial land suitable for restaurant, medical, or retail development.

    4540 Hwy 17 S, Murrells Inlet, SC 29576

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    Commercial Land Near Hospital
    $750,000
    Commercial Land Near Hospital

    Commercial land suitable for restaurant, medical, or pharmacy use.

    4540 Hwy 17 S Byp, Murrells Inlet, SC 29576

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    Off-Market Properties in Charleston, SC

    Consider similar Off-Market properties in Charleston, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1818 Remount Rd
    DENTAL BUILDING
    2,600 SF
    Value Estimation by Request

    1818 Remount Rd, Charleston, SC 29406-3239

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    1014 St Andrews Blvd
    Medical Office Space
    34,765 SF
    Value Estimation by Request

    1014 St Andrews Blvd, Charleston, SC 29407

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    18 Broad St St
    Medical Office Space
    2,167 SF
    Value Estimation by Request

    18 Broad St St, Charleston, SC 29401

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    State Rd
    Individual retail properties
    61,240 SF
    Value Estimation by Request
    State Rd

    0 State Rd, Charleston, SC 29492

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    Charleston, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 9 medical office space for sale in Charleston, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 54,500 square feet of properties for sale, with an estimated market value of $15,968,500.

    Sale prices for medical spaces in Charleston, SC start at $15,968,500, averaging $15,968,500, and reaching up to $15,968,500 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Office Units 132
    Office buildings 40
    Medical Office Space 26
    Coworking space 5
    Creative space 1

    Property Size Breakdown

    The majority of commercial real estate listings in Charleston fall within the 100,000+ square foot range.

    Demographics Overview

    Population 307K
    Population Growth (5Y) +5.8%
    Median Household Income $78,496
    College Educated 44.0%

    High-Yield Neighborhoods for Investment

    Identify Charleston submarkets with the highest inventory density on the market and evaluate the median listing prices of real estate assets

    Neighborhood Average Price
    29414 $1.8M
    29407 $1.9M

    Taxes & Financing

    Average Loan-to-Value 65.0%

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