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    Spartanburg, SC Medical Office Space for Sale

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    Boiling Springs, SC Una, SC Roebuck, SC
    6 listings
    Spartanburg Office Building For Sale
    $1,810,000
    7,200 SF
    Spartanburg Office Building For Sale

    130 Dillon Drive, Spartanburg, SC 29307

    7,200 SF office building near Spartanburg Medical District.
    • Prime location in Spartanburg, SC with excellent visibility.
    • Investment opportunity with a multi‑tenant building.
    • ±4,015 SF available, with ±3,185 SF already leased to Ortho Sport & Spine Physicians.
    • Close proximity to Spartanburg Medical District and other healthcare providers.
    • Ideal for primary care or specialty practices.
    Updated: Nov 26, 2025
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    Spartanburg Medical/Office Building For Sale
    $825,000
    9,594 SF
    Spartanburg Medical/Office Building For Sale

    1770 Skylyn Dr, Spartanburg, SC

    9,594 SF medical/office building near downtown Spartanburg.
    • Prime location just outside Downtown Spartanburg, a rapidly growing area
    • Substantial ±9,594‑SF medical/office building
    • Potential for subdivision into two tenant spaces (±6,440 SF and ±3,130 SF)
    • High visibility location
    • Ideal for medical or office use
    Updated: Mar 28, 2025
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    Medical Office Space Available
    $430,000
    4,645 SF
    Medical Office Space Available

    4,645 SF medical office space for lease.

    1241 Boiling Springs Rd, Spartanburg, SC

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    Medical/Professional Office Space Available
    $775,000
    10,000 SF
    Medical/Professional Office Space Available

    10,000 SF property near Mary Black Regional Hospital.

    125 Dillon Dr, Spartanburg, SC 29307

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    Professional Office/Medical Pads For Sale
    $150,000
    3,500 SF
    Professional Office/Medical Pads For Sale

    Two office/medical pads with utilities, parking, and infrastructure included.

    108 Burton St, Spartanburg, SC

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    Versatile Commercial Building Near Hospital
    $845,000
    11,925 SF
    Versatile Commercial Building Near Hospital

    Adaptable commercial building suitable for medical, retail, or storage use.

    200 Dillon Cir, Spartanburg, SC 29307

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    Based on your search, we've compiled 80 Potential Opportunities for your consideration. Besides 6 Active listings in Spartanburg, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 66 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Gaffney Commercial Land For Sale
    $279,000
    1.89 Acres
    Gaffney Commercial Land For Sale

    Prime commercial land with utilities available in Gaffney, SC.

    530 W Frederick Street, Gaffney, SC 29341

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    Gaffney Commercial Land For Sale
    $279,000
    1.89 Acres
    Gaffney Commercial Land For Sale

    Prime commercial location near business area and I-85.

    530,526,524 W Frederick Street, Gaffney, SC 29341

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    Medical Office Building For Sale
    $2,395,000
    7,397 SF
    Medical Office Building For Sale

    Two-story, ±7,397 SF medical office building suited for owner-occupant.

    300 Regent Park Ct, Greenville, SC

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    Freestanding Office Building For Sale
    $1,700,000
    6,046 SF
    Freestanding Office Building For Sale

    Freestanding office building in desirable Eastside office corridor.

    5 Hawthorne Park Ct, Greenville, SC 29615

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cleared Land in Greer, SC
    $209,000
    0.87 Acres
    Cleared Land in Greer, SC

    0.87-acre commercial land parcel in a high-growth area.

    Aaron Tippin Drive, Greer, SC 29650

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    High-Visibility Commercial Land For Sale
    $450,000
    0.82 Acres
    High-Visibility Commercial Land For Sale

    0.82 acre commercial land with high traffic exposure.

    4108 Old Buncombe Road, Greenville, SC 29617

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    Prime Land in Greenville, SC
    $1,800,000
    2,500 SF
    Prime Land in Greenville, SC

    11+/- acre property ideal for development in a growing corridor.

    3900 Highway 153, Greenville, SC 29611

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    Whitmire Redevelopment Opportunity
    $75,000
    3.43 Acres
    Whitmire Redevelopment Opportunity

    3.43 acre commercial tract ideal for redevelopment.

    6470 Whitmire Highway, Whitmire, SC 29178

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    Off-Market Properties in Spartanburg, SC

    Consider similar Off-Market properties in Spartanburg, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1770 Skylyn Dr
    MEDICAL BUILDING
    9,594 SF Lot: 1.21 Acres

    1770 Skylyn Dr, Spartanburg, SC 29307-1045

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    391 Henry St
    MEDICAL BUILDING
    5,279 SF Lot: 0.57 Acres
    Estimated value
    $800,000

    391 Henry St, Spartanburg, SC 29302-2639

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    397 Serpentine Dr Ste A
    MEDICAL BUILDING
    6,807 SF Lot: 0.57 Acres
    Value Estimation by Request

    397 Serpentine Dr Ste A, Spartanburg, SC 29303-3067

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    397 Serpentine Dr Ste B
    MEDICAL BUILDING
    3,272 SF Lot: 0.26 Acres
    Value Estimation by Request

    397 Serpentine Dr Ste B, Spartanburg, SC 29303-3067

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    735 Main St
    MEDICAL BUILDING
    3,941 SF Lot: 0.49 Acres
    Value Estimation by Request

    735 Main St, Spartanburg, SC 29302-1281

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    1526 John B White Sr Blvd
    MEDICAL BUILDING
    1,770 SF Lot: 0.10 Acres
    Value Estimation by Request

    1526 John B White Sr Blvd, Spartanburg, SC 29301

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    1526 John B White Sr Blvd
    MEDICAL BUILDING
    2,363 SF Lot: 0.12 Acres
    Value Estimation by Request

    1526 John B White Sr Blvd, Spartanburg, SC 29301

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    153 Oakwood Ave
    MEDICAL BUILDING
    8,724 SF Lot: 1.29 Acres
    Value Estimation by Request

    153 Oakwood Ave, Spartanburg, SC 29302

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    1330 Boiling Spgs Rd Ste, Unit 2800
    MEDICAL BUILDING
    3,530 SF Lot: 0.39 Acres
    Value Estimation by Request
    Unit 2800

    1330 Boiling Spgs Rd Ste, Spartanburg, SC 29303-4216

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    1250 John B White Sr Blvd
    MEDICAL BUILDING
    6,875 SF Lot: 0.66 Acres
    Estimated value
    $1,095,000

    1250 John B White Sr Blvd, Spartanburg, SC 29306-3929

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    480 Church St
    MEDICAL BUILDING
    5,934 SF Lot: 0.82 Acres
    Value Estimation by Request

    480 Church St, Spartanburg, SC 29303-3638

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    233 Blackstock Rd Ste J
    MEDICAL BUILDING
    1,500 SF Lot: 1.11 Acres
    Value Estimation by Request

    233 Blackstock Rd Ste J, Spartanburg, SC 29301-2652

    View details
    Pearl St
    MEDICAL BUILDING
    10,540 SF Lot: 1.13 Acres
    Estimated value
    $3,720,000

    Pearl St, Spartanburg, SC 29302

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    295 Pearl St
    MEDICAL BUILDING
    54,580 SF Lot: 2.55 Acres
    Estimated value
    $3,720,000

    295 Pearl St, Spartanburg, SC 29303-3606

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    250 Grv Medical Park Dr
    MEDICAL BUILDING
    12,836 SF Lot: 1.62 Acres
    Estimated value
    $3,190,000

    250 Grv Medical Park Dr, Spartanburg, SC 29303-4222

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    120 Dillon Dr
    MEDICAL BUILDING
    17,744 SF Lot: 3.41 Acres
    Estimated value
    $4,510,000

    120 Dillon Dr, Spartanburg, SC 29307-1018

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    115 Powell Ml Rd
    MEDICAL BUILDING
    3,549 SF Lot: 0.44 Acres
    Estimated value
    $975,000

    115 Powell Ml Rd, Spartanburg, SC 29301-1531

    View details
    740 Oak Grv Rd
    MEDICAL BUILDING
    5,511 SF Lot: 0.47 Acres
    Value Estimation by Request

    740 Oak Grv Rd, Spartanburg, SC 29301-3579

    View details

    Spartanburg, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 72 medical office space for sale in Spartanburg, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 46,864 square feet of properties for sale, with an estimated market value of $4,835,000.

    Sale prices for medical spaces in Spartanburg, SC start at $150,000, averaging $805,833, and reaching up to $1,810,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 64
    Medical Office Space 11
    Office buildings 10
    Creative space 1

    Demographics Overview

    Population 150K
    Population Growth (5Y) +8.8%
    Median Household Income $59,825
    College Educated 25.6%

    High-Yield Neighborhoods for Investment

    Identify Spartanburg submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29307 $1.1M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Spartanburg County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Spartanburg County

    Retail

    Office

    Property Size Breakdown

    The majority of commercial real estate listings in Spartanburg fall within the 10,000 to 25,000 square foot range.

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