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    Richland County, SC Medical Office Space for Sale

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    Columbia, SC Myrtle Beach, SC Hilton Head Island, SC Greenville, SC Charleston, SC Spartanburg, SC Anderson, SC Aiken, SC
    11 properties
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    Renovated Office Building
    Updated: Dec 3, 2025
    Renovated Office Building

    8311 Two Notch Road, Columbia, SC 29223

    $850,000
    5,969 sqft
    5,969 SF fully renovated office building
    Multiple private entrances support multi‑tenant use or separated business functions
    Conference room with updated interior finishes
    Kitchen and break area included
    Substantial storage space for business operations
    View details
    Class A Medical Office Building
    Updated: Oct 19
    Class A Medical Office Building

    140 Wildewood Park Dr, Columbia, SC 29223

    $2,700,000
    17,838 sqft
    ±17,838 SF Class A office and medical building
    Built in 2006
    On‑site parking ratio of 3.81 per 1,000 RSF
    Northeast Columbia location off Two Notch Road
    Available for sale or lease with flexible lease terms
    View details
    Freestanding Spa and Wellness Property
    Freestanding Spa and Wellness Property

    7211 Broad River Rd, Irmo, SC 29063

    Contact for pricing
    3,845 sqft 0.51 AC lot

    Freestanding salon building at a signalized intersection with parking and proximity to major healthcare and retail destinations.

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    Realmo Analytics Monitor Off-market properties and contact owners who are ready to sell. Many signals applied to make quality leads for you. Get Leads
    Medical Office with Exam Rooms
    Medical Office with Exam Rooms

    125 ALPINE CIR, Columbia, SC 29223

    Contact for pricing
    5,017 sqft

    A reception and waiting area connects to private offices, exam rooms, and a separate staff zone.

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    Office Building with Courtyard
    Office Building with Courtyard

    2712 Middleburg Dr, Columbia, SC 29204

    Contact for pricing
    48,184 sqft 3.32 AC lot

    Partially occupied office property with vacant suites available for immediate upfit and occupancy.

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    Four-Story Medical Office Building
    Four-Story Medical Office Building

    8 Medical Park Road, Columbia, SC 29203

    Contact for pricing

    Connected to Prisma Health Heart Hospital, the property is master-leased to Prisma Health-Midlands under a net lease.

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    NNN Dental Property
    NNN Dental Property

    4547 Hardscrabble Rd, Columbia, SC 29229

    Contact for pricing

    Heartland Dental leases the recently built property, with four extension periods available beyond its initial term.

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    Turnkey Dental Office For Sale
    Turnkey Dental Office For Sale

    741 Greenlawn Dr, Columbia, SC 29209

    Contact for pricing
    4,325 sqft

    Dental office for sale in Southeast Columbia near Garners Ferry.

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    Second-Floor Medical Office Suite, Suite 200
    Second-Floor Medical Office Suite, Suite 200

    2113 Adams Grove, Columbia, SC 29203

    Contact for pricing
    11,131 sqft

    Second-floor medical office suite with a large central waiting room and 8 exam rooms plus 2 procedure rooms.

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    Medical Office with Imaging Rooms
    Medical Office with Imaging Rooms

    74 Polo Rd, Columbia, SC 29223

    Contact for pricing
    9,975 sqft

    Specialized clinical layout includes diagnostic rooms, laboratory space, offices, and on-site parking.

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    Medical Office Condo For Sale
    Medical Office Condo For Sale

    2113 Adams Grove, Columbia, SC 29203

    Contact for pricing
    22,263 sqft

    Class A medical office condo available for sale or lease.

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    11 active listings match your search: Medical Office for sale in Richland County, SC. Based on your search, we've also compiled 16 Potential Opportunities for your consideration: 14 off-market properties to explore as potential leads and 2 land listings with development potential.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Office/Institutional Development Land
    Office/Institutional Development Land

    401 Arrowwood Road, Columbia, SC 29210

    $169,000
    1.61 AC lot

    OI-zoned site supports medical, professional office, educational, and community facility development with access to regional roadways.

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    Commercial Land with Utility Access
    Commercial Land with Utility Access

    2551 Augusta Highway lot: 0, Lexington, SC 29072

    $3,400,000
    9.06 AC lot

    ID-zoned tract with public water and multiple utilities serving the site.

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    Off-Market Properties in Richland County, SC

    Consider similar Off-Market properties in Richland County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    392 St Andrews Rd
    Medical Office Space

    392 St Andrews Rd, Columbia, SC 29210

    Estimated value: by Request
    2,915 sqft
    View details
    1072 Wildewood Ctr Dr
    Medical Office Space

    1072 Wildewood Ctr Dr, Columbia, SC 29229

    Estimated value: by Request
    14,580 sqft
    View details
    565 Spears Creek Church Rd
    Medical Office Space

    565 Spears Creek Church Rd, Elgin, SC 29045

    Estimated value: by Request
    8,450 sqft
    View details
    120 Highland Center Dr
    Medical Office Space

    120 Highland Center Dr, Columbia, SC 29201

    Estimated value: by Request
    2,959 sqft
    View details
    10526 Two Notch Rd
    Restaurants

    10526 Two Notch Rd, Elgin, SC 29045

    Estimated value: by Request
    66,773 sqft 8.75 AC lot
    View details
    1701 St Julian Pl
    Medical Office Space

    1701 St Julian Pl, Columbia, SC 29204

    Estimated value: by Request
    14,442 sqft
    View details
    2750 Bernardin Ave
    Medical Office Space

    2750 Bernardin Ave, Columbia, SC 29206

    Estimated value: by Request
    126,002 sqft
    View details
    1777 St Julian Pl
    Medical Office Space

    1777 St Julian Pl, Columbia, SC 29204

    Estimated value: by Request
    43,000 sqft
    View details
    1706 St Julian Pl
    Medical Office Space

    1706 St Julian Pl, Columbia, SC 29204

    Estimated value: by Request
    12,395 sqft
    View details
    1501 Main Columbia St
    Medical Office Space

    1501 Main Columbia St, Columbia, SC 29201

    Estimated value: by Request
    View details
    Longtown Rd
    Medical Office Space

    0 Longtown Rd, Columbia, SC undefined

    Estimated value: by Request
    9,796 sqft 1.41 AC lot
    View details
    1126 Us-321
    Medical Office Space

    1126 Us-321, Winnsboro, SC 29180

    Estimated value: by Request
    74,322 sqft 8.01 AC lot
    View details
    Longtown Rd
    Medical Office Space

    0 Longtown Rd, Columbia, SC 29229

    Estimated value: by Request
    9,875 sqft 1.41 AC lot
    View details

    Richland County, SC Medical Office Space Market Trends and Statistics

    Explore 25 medical office space for sale in Richland County, SC, showcased through 11 active listings on our real estate platform. These investment opportunities span a total of 128,547 square feet of properties for sale, with an estimated market value of $3,550,000.

    Sale prices for medical spaces in Richland County, SC start at $850,000, averaging $1,775,000, and reaching up to $2,700,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Featured Richland County Real Estate Agencies

    Realmo connects you with licensed Richland County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Real Estatee Professional
    Real Estate Professional, 71 sunset maple court Blythewood, SC 29016
    Phone: (803) 360-4098
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