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    Spartanburg County, SC Medical Office Space for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    7 results
    Commercial Land Near Highway 290
    $1,250,000
    1,250 SF
    Commercial Land Near Highway 290

    6046 Reidville Road, Moore, SC 29369

    5.2 acres near intersection of Hwy 290 and SC 296.
    • Prime location near the intersection of Hwy 290 and SC 296 in Moore, SC
    • 5.2 level acres of commercial land
    • High traffic count of 13,000 vehicles daily with 351 ft of road frontage on SC296
    • Directly beside River Ridge Elementary School and backs up to River Falls Golf Course
    • Suitable for various commercial developments
    Updated: Jun 14, 2025
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    Spartanburg Office Building For Sale
    $1,810,000
    7,200 SF
    Spartanburg Office Building For Sale

    130 Dillon Drive, Spartanburg, SC 29307

    7,200 SF office building near Spartanburg Medical District.
    • Prime location in Spartanburg, SC with excellent visibility.
    • Investment opportunity with a multi‑tenant building.
    • ±4,015 SF available, with ±3,185 SF already leased to Ortho Sport & Spine Physicians.
    • Close proximity to Spartanburg Medical District and other healthcare providers.
    • Ideal for primary care or specialty practices.
    Updated: Nov 26, 2025
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    Medical/Professional Office Space Available
    $775,000
    10,000 SF
    Medical/Professional Office Space Available

    10,000 SF property near Mary Black Regional Hospital.

    125 Dillon Dr, Spartanburg, SC 29307

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    Spartanburg Medical/Office Building For Sale
    $825,000
    9,594 SF
    Spartanburg Medical/Office Building For Sale

    9,594 SF medical/office building near downtown Spartanburg.

    1770 Skylyn Dr, Spartanburg, SC

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    Medical Office Space Available
    $430,000
    4,645 SF
    Medical Office Space Available

    4,645 SF medical office space for lease.

    1241 Boiling Springs Rd, Spartanburg, SC

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    Professional Office/Medical Pads For Sale
    $150,000
    3,500 SF
    Professional Office/Medical Pads For Sale

    Two office/medical pads with utilities, parking, and infrastructure included.

    108 Burton St, Spartanburg, SC

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    Versatile Commercial Building Near Hospital
    $845,000
    11,925 SF
    Versatile Commercial Building Near Hospital

    Adaptable commercial building suitable for medical, retail, or storage use.

    200 Dillon Cir, Spartanburg, SC 29307

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 7 Active listings in Spartanburg County, SC, we suggest exploring several alternatives: similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cleared Land in Greer, SC
    $209,000
    0.87 Acres
    Cleared Land in Greer, SC

    0.87-acre commercial land parcel in a high-growth area.

    Aaron Tippin Drive, Greer, SC 29650

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    Mauldin Commercial Lot For Sale
    $200,000
    1.00 Acre
    Mauldin Commercial Lot For Sale

    One-acre commercial lot in a rapidly growing Mauldin area.

    Corn and Miller Road, Mauldin, SC 29607

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    Prime Corner Lot in Mauldin
    $200,000
    1.00 Acre
    Prime Corner Lot in Mauldin

    Highly visible commercial land with development potential in a growing area.

    Corn and Miller Road, Mauldin, SC 29607

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    High-Visibility Commercial Land For Sale
    $450,000
    0.82 Acres
    High-Visibility Commercial Land For Sale

    0.82 acre commercial land with high traffic exposure.

    4108 Old Buncombe Road, Greenville, SC 29617

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    Off-Market Properties in Spartanburg County, SC

    Consider similar Off-Market properties in Spartanburg County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3610 Moore Duncan Hwy
    MEDICAL BUILDING
    5,176 SF Lot: 1.18 Acres

    3610 Moore Duncan Hwy, Moore, SC 29369-9414

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    654 Arlington Rd
    MEDICAL BUILDING
    4,624 SF Lot: 0.67 Acres
    Value Estimation by Request

    654 Arlington Rd, Greer, SC 29651-1544

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    1770 Skylyn Dr
    MEDICAL BUILDING
    9,594 SF Lot: 1.21 Acres

    1770 Skylyn Dr, Spartanburg, SC 29307-1045

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    2740 Hwy 14
    MEDICAL BUILDING
    Lot: 18.43 Acres
    Estimated value
    $22,000,000

    2740 Hwy 14, Greer, SC 29650-4922

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    391 Henry St
    MEDICAL BUILDING
    5,279 SF Lot: 0.57 Acres
    Estimated value
    $800,000

    391 Henry St, Spartanburg, SC 29302-2639

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    397 Serpentine Dr Ste A
    MEDICAL BUILDING
    6,807 SF Lot: 0.57 Acres
    Value Estimation by Request

    397 Serpentine Dr Ste A, Spartanburg, SC 29303-3067

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    397 Serpentine Dr Ste B
    MEDICAL BUILDING
    3,272 SF Lot: 0.26 Acres
    Value Estimation by Request

    397 Serpentine Dr Ste B, Spartanburg, SC 29303-3067

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    735 Main St
    MEDICAL BUILDING
    3,941 SF Lot: 0.49 Acres
    Value Estimation by Request

    735 Main St, Spartanburg, SC 29302-1281

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    1526 John B White Sr Blvd
    MEDICAL BUILDING
    1,770 SF Lot: 0.10 Acres
    Value Estimation by Request

    1526 John B White Sr Blvd, Spartanburg, SC 29301

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    1526 John B White Sr Blvd
    MEDICAL BUILDING
    2,363 SF Lot: 0.12 Acres
    Value Estimation by Request

    1526 John B White Sr Blvd, Spartanburg, SC 29301

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    2555 Boiling Spgs Rd
    MEDICAL BUILDING
    13,374 SF Lot: 1.09 Acres
    Estimated value
    $1,660,000

    2555 Boiling Spgs Rd, Boiling Springs, SC 29316-5351

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    601 Georgia St
    MEDICAL BUILDING
    3,515 SF Lot: 1.92 Acres
    Value Estimation by Request

    601 Georgia St, Woodruff, SC 29388-1953

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    900 Rutherford St
    MEDICAL BUILDING
    1,200 SF Lot: 0.56 Acres
    Value Estimation by Request

    900 Rutherford St, Landrum, SC 29356-1725

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    5052 Hwy 9th 9
    MEDICAL BUILDING
    4,597 SF Lot: 2.00 Acres
    Estimated value
    $2,350,000

    5052 Hwy 9th 9, Inman, SC 29349

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    153 Oakwood Ave
    MEDICAL BUILDING
    8,724 SF Lot: 1.29 Acres
    Value Estimation by Request

    153 Oakwood Ave, Spartanburg, SC 29302

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    2755 Hwy 14
    MEDICAL BUILDING
    2,038 SF Lot: 0.00 Acres
    Value Estimation by Request

    2755 Hwy 14, Greer, SC 29650-4926

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    1330 Boiling Spgs Rd Ste, Unit 2800
    MEDICAL BUILDING
    3,530 SF Lot: 0.39 Acres
    Value Estimation by Request
    Unit 2800

    1330 Boiling Spgs Rd Ste, Spartanburg, SC 29303-4216

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    Spartanburg County, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 72 medical office space for sale in Spartanburg County, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 48,114 square feet of properties for sale, with an estimated market value of $6,085,000.

    Sale prices for medical spaces in Spartanburg County, SC start at $150,000, averaging $869,285, and reaching up to $1,810,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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