Spartanburg County, SC Medical Office Space for sale

Updated: Jun 23

Medical Office Building

1250 John B White Sr Boulevard, Spartanburg, SC 29306

$1,295,000

6,875 sqft

6,875‑square‑foot medical office property
Located at 1250 John B White Sr Boulevard
Spartanburg, SC 29306 address

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Updated: Nov 26, 2025

Spartanburg Office Building For Sale

130 Dillon Drive, Spartanburg, SC 29307

$1,450,000

7,200 sqft

Prime location in Spartanburg, SC with excellent visibility.
Investment opportunity with a multi‑tenant building.
±4,015 SF available**, with ±3,185 SF already leased to Ortho Sport & Spine Physicians.
Close proximity to Spartanburg Medical District and other healthcare providers.
Ideal for primary care or specialty practices.

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All-Brick Medical Office Building

108 W Rutherford St, Landrum, SC 29356

Contact for pricing

2,400 sqft

All-brick medical office building with exam rooms, multiple lobbies and reception areas, and private parking.

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Medical/Professional Office Space Available

125 Dillon Dr, Spartanburg, SC 29307

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10,000 sqft 1.30 AC lot

10,000 SF property near Mary Black Regional Hospital.

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Medical Office Building with Parking

1776 Skylyn Dr, Spartanburg, SC 29307

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11,832 sqft

Medical office building with numerous exam, treatment, and procedure rooms and ample on-site parking.

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Office and Medical Building

1704 East Main St, Duncan, SC 29334

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3,048 sqft

Office/medical use building on Highway 290 in Duncan, with additional land available for potential mixed-use redevelopment.

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16-Chair Dialysis Medical Office

196 Sloane Garden Rd, Boiling Springs, SC 29316

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Build-to-suit clinic with a long-term lease, scheduled increases, and multiple extension options.

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Two-Unit Medical Office Property

365 E Blackstock Rd, Spartanburg, SC 29301

Contact for pricing

Flexible medical and professional office configuration with specialized treatment areas and the option to combine the suites.

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Medical Office with Fenced Lot

991 Asheville Hwy, Spartanburg, SC 29303

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Former veterinary clinic with surface parking and additional land.

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Based on your search, we've compiled 73 Potential Opportunities for your consideration. Besides 9 Active listings in Spartanburg County, SC, we suggest exploring several alternatives: similar 63 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cleared Commercial Land

4 Aaron Tippin Drive, Greer, SC 29650

$194,000

0.87 AC lot

Level OP-zoned site with public water and sewer available for office, medical, and professional development.

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Off-Market Properties in Spartanburg County, SC

Consider similar Off-Market properties in Spartanburg County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

MEDICAL BUILDING

3610 Moore Duncan Hwy, Moore, SC 29369-9414

$685,000

Estimated value

5,176 sqft 1.18 AC lot

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MEDICAL BUILDING

Value Estimation by Request

3,515 sqft 1.92 AC lot

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MEDICAL BUILDING

900 Rutherford St, Landrum, SC 29356-1725

$195,000

Estimated value

1,200 sqft 0.56 AC lot

View details

MEDICAL BUILDING

5052 Hwy 9th 9, Inman, SC 29349

$2,350,000

Estimated value

4,597 sqft 2.00 AC lot

View details

MEDICAL BUILDING

153 Oakwood Ave, Spartanburg, SC 29302

$370,000

Estimated value

8,724 sqft 1.29 AC lot

View details

Spartanburg County, SC Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Spartanburg County, SC, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 41,355 square feet of properties for sale, with an estimated market value of $2,745,000.

Sale prices for medical spaces in Spartanburg County, SC start at $1,295,000, averaging $1,372,500, and reaching up to $1,450,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Featured Spartanburg County Real Estate Agencies

Realmo connects you with licensed Spartanburg County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Realty Spartanburg Partners

1707 John B White Sr Blvd, Suite E Spartanburg, SC 29301

Phone: 18645746000

www.kwspartanburg.com

Century 21 Blackwell & Co.

2260 Boiling Springs Road Boiling Springs, SC 29316

Phone: 18645960322

www.century21blackwell.com

Better Homes and Gardens Young & Company

8291 Warren H. Abernathy Highway Spartanburg, SC 29301

Phone: 19706605323

bhgyoung.com