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    Spartanburg County, SC Medical Office Space for Sale

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    Spartanburg Office Building For Sale
    Updated: Nov 26, 2025
    Spartanburg Office Building For Sale

    130 Dillon Drive, Spartanburg, SC 29307

    $1,810,000
    7,200 sqft
    Prime location in Spartanburg, SC with excellent visibility.
    Investment opportunity with a multi‑tenant building.
    ±4,015 SF available, with ±3,185 SF already leased to Ortho Sport & Spine Physicians.
    Close proximity to Spartanburg Medical District and other healthcare providers.
    Ideal for primary care or specialty practices.
    View details
    Medical/Professional Office Space Available
    Updated: Feb 17
    Medical/Professional Office Space Available

    125 Dillon Dr, Spartanburg, SC 29307

    $775,000
    10,000 sqft 1.30 AC lot
    Directly adjacent to Mary Black Regional Hospital
    Ideal location for medical or professional office use
    ±10,000 SF on ±1.30 AC
    Low‑interest owner‑financing terms considered
    Located in an established office park with excellent accessibility
    View details
    Spartanburg Medical/Office Building For Sale
    Spartanburg Medical/Office Building For Sale

    1770 Skylyn Dr, Spartanburg, SC

    $825,000
    9,594 sqft 1.21 AC lot

    9,594 SF medical/office building near downtown Spartanburg.

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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Adaptive Retail and Office Site
    Adaptive Retail and Office Site

    467 Cross Anchor Rd, Woodruff, SC 29388

    $1,150,000

    Open-plan commercial layout with excess land for parking or outside storage and a loading dock for practical day-to-day operations.

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    Medical Office Space Available
    Medical Office Space Available

    1241 Boiling Springs Rd, Spartanburg, SC

    $430,000
    4,645 sqft 0.50 AC lot

    4,645 SF medical office space for lease.

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    Versatile Commercial Building Near Hospital
    Versatile Commercial Building Near Hospital

    200 Dillon Cir, Spartanburg, SC 29307

    $845,000
    11,925 sqft

    Adaptable commercial building suitable for medical, retail, or storage use.

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    Professional Office/Medical Pads For Sale
    Professional Office/Medical Pads For Sale

    108 Burton St, Spartanburg, SC

    $150,000
    3,500 sqft 0.40 AC lot

    Two office/medical pads with utilities, parking, and infrastructure included.

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    Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 7 Active listings in Spartanburg County, SC, we suggest exploring several alternatives: similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cleared Land in Greer, SC
    Cleared Land in Greer, SC

    Aaron Tippin Drive, Greer, SC 29650

    $209,000
    0.87 AC lot

    0.87-acre commercial land parcel in a high-growth area.

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    High-Visibility Commercial Land For Sale
    High-Visibility Commercial Land For Sale

    4108 Old Buncombe Road, Greenville, SC 29617

    $450,000
    0.82 AC lot

    0.82 acre commercial land with high traffic exposure.

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    Prime Land in Greenville, SC
    Prime Land in Greenville, SC

    3900 Highway 153, Greenville, SC 29611

    $1,800,000
    2,500 sqft 10.91 AC lot

    11+/- acre property ideal for development in a growing corridor.

    View details
    Whitmire Redevelopment Opportunity
    Whitmire Redevelopment Opportunity

    6470 Whitmire Highway, Whitmire, SC 29178

    $75,000
    3.43 AC lot

    3.43 acre commercial tract ideal for redevelopment.

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    Off-Market Properties in Spartanburg County, SC

    Consider similar Off-Market properties in Spartanburg County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3610 Moore Duncan Hwy
    MEDICAL BUILDING

    3610 Moore Duncan Hwy, Moore, SC 29369-9414

    $685,000
    Estimated value
    5,176 sqft 1.18 AC lot
    View details
    654 Arlington Rd
    MEDICAL BUILDING

    654 Arlington Rd, Greer, SC 29651-1544

    Value Estimation by Request
    4,624 sqft 0.67 AC lot
    View details
    1770 Skylyn Dr
    MEDICAL BUILDING

    1770 Skylyn Dr, Spartanburg, SC 29307-1045

    $565,000
    Estimated value
    9,594 sqft 1.21 AC lot
    View details
    2740 Hwy 14
    MEDICAL BUILDING

    2740 Hwy 14, Greer, SC 29650-4922

    $22,000,000
    Estimated value
    18.43 AC lot
    View details
    391 Henry St
    MEDICAL BUILDING

    391 Henry St, Spartanburg, SC 29302-2639

    $800,000
    Estimated value
    5,279 sqft 0.57 AC lot
    View details
    397 Serpentine Dr Ste A
    MEDICAL BUILDING

    397 Serpentine Dr Ste A, Spartanburg, SC 29303-3067

    Value Estimation by Request
    6,807 sqft 0.57 AC lot
    View details
    397 Serpentine Dr Ste B
    MEDICAL BUILDING

    397 Serpentine Dr Ste B, Spartanburg, SC 29303-3067

    Value Estimation by Request
    3,272 sqft 0.26 AC lot
    View details
    735 Main St
    MEDICAL BUILDING

    735 Main St, Spartanburg, SC 29302-1281

    Value Estimation by Request
    3,941 sqft 0.49 AC lot
    View details
    1526 John B White Sr Blvd
    MEDICAL BUILDING

    1526 John B White Sr Blvd, Spartanburg, SC 29301

    Value Estimation by Request
    1,770 sqft 0.10 AC lot
    View details
    1526 John B White Sr Blvd
    MEDICAL BUILDING

    1526 John B White Sr Blvd, Spartanburg, SC 29301

    Value Estimation by Request
    2,363 sqft 0.12 AC lot
    View details
    2555 Boiling Spgs Rd
    MEDICAL BUILDING

    2555 Boiling Spgs Rd, Boiling Springs, SC 29316-5351

    $1,660,000
    Estimated value
    13,374 sqft 1.09 AC lot
    View details
    601 Georgia St
    MEDICAL BUILDING

    601 Georgia St, Woodruff, SC 29388-1953

    Value Estimation by Request
    3,515 sqft 1.92 AC lot
    View details
    900 Rutherford St
    MEDICAL BUILDING

    900 Rutherford St, Landrum, SC 29356-1725

    Value Estimation by Request
    1,200 sqft 0.56 AC lot
    View details
    5052 Hwy 9th 9
    MEDICAL BUILDING

    5052 Hwy 9th 9, Inman, SC 29349

    $2,350,000
    Estimated value
    4,597 sqft 2.00 AC lot
    View details
    153 Oakwood Ave
    MEDICAL BUILDING

    153 Oakwood Ave, Spartanburg, SC 29302

    Value Estimation by Request
    8,724 sqft 1.29 AC lot
    View details
    2755 Hwy 14
    MEDICAL BUILDING

    2755 Hwy 14, Greer, SC 29650-4926

    Value Estimation by Request
    2,038 sqft
    View details
    1330 Boiling Spgs Rd Ste, Unit 2800
    MEDICAL BUILDING

    1330 Boiling Spgs Rd Ste, Spartanburg, SC 29303-4216

    Unit 2800
    Value Estimation by Request
    3,530 sqft 0.39 AC lot
    View details

    Spartanburg County, SC Medical Office Space Market Trends and Statistics

    Explore 72 medical office space for sale in Spartanburg County, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 46,864 square feet of properties for sale, with an estimated market value of $4,835,000.

    Sale prices for medical spaces in Spartanburg County, SC start at $150,000, averaging $805,833, and reaching up to $1,810,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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