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    North Charleston, SC Medical Office Space for Sale

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    N Charleston, SC Hanahan, SC Goose Creek, SC
    Former Daycare Near Navy Yard
    $2,300,000
    12,895 SF
    Former Daycare Near Navy Yard

    1910 McMillan Avenue, North Charleston, SC 29405

    12,895 SF former daycare near new Navy Yard project.
    • Located just outside the new Navy Yard redevelopment project (retail, office, residential, mixed‑use).
    • Former daycare facility with capacity for 300 children.
    • $546k of New FF&E and Tenant Improvements since 2022, including a new roof and 3 replaced HVAC Units (9 total).
    • Suitable for daycare/preschool, medical/professional office, church, or financial service institution.
    • Proximity to the Lowcountry Rapid Transit System (coming in 2026).
    Updated: Mar 6
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    Dorchester Road Office Space Available
    $1,150,000
    6,600 SF
    Dorchester Road Office Space Available

    7880-7890 Dorchester Rd, North Charleston, SC

    High-traffic location with flexible spaces for professional uses.
    • High‑traffic, visible location on Dorchester Rd.
    • Subdividable space (4,350 and 2,250 sq ft) suitable for professional firms.
    • Ample fenced parking with a ratio of 1:140 sq ft.
    • Fresh exterior renovations including paint, awnings, and pavement.
    • Tenant improvement allowance negotiable for qualified clients with 5- and 10‑year lease options.
    Updated: Nov 4, 2025
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    North Charleston Medical Office Building
    $1,500,000
    4,345 SF
    North Charleston Medical Office Building

    Commercial property suitable for medical or professional office use.

    3800 Faber Place Drive, North Charleston, SC 29405

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    White Hall Center Office Condo
    $549,900
    2,000 SF
    White Hall Center Office Condo

    Office condo in White Hall Center, North Charleston.

    5401 Netherby Lane Ste 102, North Charleston, SC 29420

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    Renovated Office Building Near I-26
    Contact for pricing
    71,711 SF
    Renovated Office Building Near I-26

    71,354 SF office building with recent $2M renovation.

    4975 Lacross Road, North Charleston, SC 29406

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    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 5 Active listings in North Charleston, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 16 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Free-Standing Office Building
    $895,000
    5,000 SF
    Free-Standing Office Building

    A flexible office layout offers private offices, open bullpen space, and exam-ready rooms for medical or legal use.

    4476 Leeds Place West, Charleston, SC 29405

    View details
    Northbridge Executive Park Investment
    $15,968,500
    54,500 SF
    Northbridge Executive Park Investment

    Two-building office campus near Ashley Landing redevelopment.

    1176-1180 Sam Rittenberg Blvd, Charleston, SC

    View details
    Medical Office Space Available
    $2,050,000
    2,423 SF
    Medical Office Space Available

    Professional office suites for lease in thriving medical complex.

    85 Springview Ln, Summerville, SC

    View details
    Nexton Mixed-Use Development Opportunity
    $18,000,000
    30,000 SF
    Nexton Mixed-Use Development Opportunity

    Mixed-use property for sale or lease in Nexton, Summerville.

    1227 Nexton Pkwy, Summerville, SC 29486

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Beaufort Land for Sale
    $459,000
    7.32 Acres
    Beaufort Land for Sale

    7.32 acre commercial land in Beaufort, South Carolina.

    Goethe Hill Road lot: 3, Beaufort, SC 29906

    View details
    Prime Commercial Land Pawleys Island
    $450,000
    0.52 Acres
    Prime Commercial Land Pawleys Island

    Commercial real estate near Highway 17 and Litchfield By The Sea.

    Portion Wall St., Pawleys Island, SC 29585

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    Commercial Land in Murrells Inlet
    $750,000
    0.89 Acres
    Commercial Land in Murrells Inlet

    Commercial land suitable for restaurant, medical, or retail development.

    4540 Hwy 17 S, Murrells Inlet, SC 29576

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    Commercial Land Near Hospital
    $750,000
    Commercial Land Near Hospital

    Commercial land suitable for restaurant, medical, or pharmacy use.

    4540 Hwy 17 S Byp, Murrells Inlet, SC 29576

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    Off-Market Properties in North Charleston, SC

    Consider similar Off-Market properties in North Charleston, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3796 Ashley Phosphate Rd
    MEDICAL BUILDING
    2,496 SF Lot: 0.37 Acres
    Estimated value
    $735,000

    3796 Ashley Phosphate Rd, North Charleston, SC 29418-8560

    View details
    8720 Dorchester Rd
    MEDICAL BUILDING
    6,582 SF Lot: 0.72 Acres
    Estimated value
    $1,860,000

    8720 Dorchester Rd, North Charleston, SC 29420-7303

    View details
    8445 Dorchester Rd
    MEDICAL BUILDING
    4,699 SF Lot: 0.66 Acres
    Estimated value
    $1,000,000

    8445 Dorchester Rd, North Charleston, SC 29420-7307

    View details
    5401 Netherby Ln Ste, Unit 1201
    MEDICAL BUILDING
    1,852 SF Lot: 0.04 Acres
    Value Estimation by Request
    Unit 1201

    5401 Netherby Ln Ste, North Charleston, SC 29420-7363

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    5306 Parkshire Way
    MEDICAL BUILDING
    2,752 SF Lot: 0.79 Acres
    Estimated value
    $610,000

    5306 Parkshire Way, North Charleston, SC 29418-2000

    View details
    5401 Netherby Ln, Unit 500
    MEDICAL BUILDING
    1,910 SF Lot: 0.05 Acres
    Value Estimation by Request
    Unit 500

    5401 Netherby Ln, North Charleston, SC 29420-7363

    View details
    5401 Netherby Ln, Unit 500
    MEDICAL BUILDING
    1,910 SF Lot: 0.05 Acres
    Value Estimation by Request
    Unit 500

    5401 Netherby Ln, North Charleston, SC 29420-7363

    View details
    8471 Resolute Way
    MEDICAL BUILDING
    7,452 SF Lot: 1.88 Acres
    Estimated value
    $1,490,000

    8471 Resolute Way, North Charleston, SC 29420-7390

    View details
    8385 Dorchester Rd
    MEDICAL BUILDING
    2,970 SF Lot: 1.38 Acres
    Estimated value
    $660,000

    8385 Dorchester Rd, North Charleston, SC 29418-2916

    View details
    5300 Archdale Blvd
    MEDICAL BUILDING
    11,453 SF Lot: 1.46 Acres
    Estimated value
    $2,315,000

    5300 Archdale Blvd, North Charleston, SC 29418-3343

    View details
    5325 Appian Way
    MEDICAL BUILDING
    5,301 SF Lot: 0.69 Acres
    Estimated value
    $1,115,000

    5325 Appian Way, North Charleston, SC 29420-7234

    View details
    2165-2185 Ashley Phosphate Rd
    Coworking space
    20,274 SF Lot: 3.00 Acres
    Value Estimation by Request

    2165-2185 Ashley Phosphate Rd, North Charleston, SC 29406

    View details
    3844 Leeds Ave
    Coworking space
    Value Estimation by Request

    3844 Leeds Ave, North Charleston, SC 29405

    View details
    2680 Elms Plantation Blvd
    Medical Office Space
    Value Estimation by Request

    2680 Elms Plantation Blvd, North Charleston, SC 29406

    View details
    5965 Core Rd
    Office Units
    32,456 SF
    Value Estimation by Request

    5965 Core Rd, North Charleston, SC 29406

    View details
    5401 Netherby Ln
    Individual retail properties
    2,000 SF
    Value Estimation by Request

    5401 Netherby Ln, North Charleston, SC 29420

    View details

    North Charleston, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 21 medical office space for sale in North Charleston, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 25,840 square feet of properties for sale, with an estimated market value of $5,499,900.

    Sale prices for medical spaces in North Charleston, SC start at $549,900, averaging $1,374,975, and reaching up to $2,300,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 68
    Office buildings 24
    Medical Office Space 13
    Coworking space 4
    Creative space 1

    Demographics Overview

    Population 129K
    Population Growth (5Y) -1.5%
    Median Household Income $62,544
    College Educated 23.5%

    High-Yield Neighborhoods for Investment

    Identify North Charleston submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29420 $549.9K
    29405 $1.9M

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Charleston County

    New Delisted

    Property Size Breakdown

    The majority of commercial real estate listings in North Charleston fall within the 100,000+ square foot range.

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