Lexington County, SC Medical Office Space for sale

Renovated Commercial Building in Columbia

$250,000

1,138 SF

Renovated Commercial Building in Columbia

3201 Broad River Road, Columbia, SC 29210

Multi-tenant property suitable for retail, medical, or aviation businesses.

Excellent location in the heart of Columbia, SC, with easy access to I‑20 and I‑26 and 8 minutes from downtown.
Completely renovated in 2014.
Multi‑tenant property suitable for retail, medical office, salon, or boutique.
Huge parking area with 15 spaces and roundabout driveway.
Currently operating as an aviation instructor academy and medical spa with existing infrastructure.

Updated: Apr 23

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$169,000

1,800 SF

Single-Tenant Office Building

326 E Church Street, Leesville, SC 29070

1,800 SF office building on a compact lot with access off Highway 23 in Leesville.

Excellent visibility and accessibility off Highway 23.
Versatile 1,800 SF office building with mixed‑use potential.
Conveniently located minutes from Columbia and Aiken, with easy access to Lake Murray.
Low Lexington County taxes and strong area growth.
Ideal for small businesses or professional services.

Updated: Mar 16

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$1,250,000

3,200 SF

Freestanding Medical Office Investment

Freestanding medical office building for sale in Northeast Columbia.

131 Wildewood Park Drive, Columbia, SC 29223

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$7,350,000

39,722 SF

West Columbia Medical/Office Park

Four Class A buildings, 100% occupied, located on Sunset Boulevard.

3221, 3223, 3225, & 3231 Sunset Blvd., West Columbia, SC 29169

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$2,750,000

5.89 Acres

Lexington Commercial Land For Sale

Pad-ready commercial parcel in high-traffic area, Lexington, SC.

206 BO TIRE Way, Lexington, SC 29072

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High-Visibility Business/Office Center For Sale

$2,250,000

15,593 SF

High-Visibility Business/Office Center For Sale

Office/retail building with high visibility and customer parking.

7358 Garners Ferry, Columbia, SC 29209

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High-Traffic Commercial Center with Suites

$2,150,000

15,593 SF

High-Traffic Commercial Center with Suites

Highly visible commercial center with 41 suites in Columbia, SC.

7358 Garners Ferry, Columbia, SC 29209

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$975,000

5,528 SF

Downtown Office Condos For Sale

Four office condos totaling 5,528 SF in downtown Columbia.

2757 Laurel St, Columbia, SC

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$275,000

1.96 Acres

Leesville Commercial Land Opportunity

1.96 acres suitable for retail, medical, or office development.

0 E Church Street, Leesville, SC 29070

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Medical/Office Building Near Lexington Medical

$1,145,000

6,300 SF

Medical/Office Building Near Lexington Medical

6,300 SF building suitable for medical or traditional office use.

101 Medical Cir, West Columbia, SC

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$2,145,000

12,956 SF

West Columbia Office/Medical Building

12,956 SF office/medical building in high-demand corridor.

3221-3231 Sunset Blvd, West Columbia, SC

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$1,850,000

14,442 SF

Medical Office Building For Sale

Medical office building with ample parking near medical campuses.

1701 Saint Julian Pl, Columbia, SC

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$2,190,000

4,715 SF

Medical NNN Investment Opportunity

Single tenant medical property for sale in Lexington, SC.

125 Park Pl Ct, Lexington, SC 29072

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Columbia Office/Medical Building For Sale

$3,000,000

25,000 SF

Columbia Office/Medical Building For Sale

Office or medical building with flexible floorplates in Columbia.

1527 Park St, Columbia, SC

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$3,150,000

9,875 SF

Turn-Key Medical Office in Columbia

Class A medical office in NE Columbia with flexible layout.

229 Longtown Rd, Columbia, SC

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$375,000

2,600 SF

Former Day Care Commercial Facility

Formerly operated day care; versatile for medical office, retail, or services with strong exposure and easy access.

305 Veterans Road, Columbia, SC 29209

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Downtown Chapin Commercial Space Available

$400,000

1,410 SF

Downtown Chapin Commercial Space Available

Commercial space suitable for various businesses in downtown Chapin, SC.

104 East Boundary Street, Chapin, SC 29036

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West Columbia Medical Office Opportunity

$4,000,000

10,840 SF

West Columbia Medical Office Opportunity

Medical office building for sale in West Columbia, SC.

110 Medical Cir, West Columbia, SC 29169

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Versatile Commercial Property Near Columbia

$399,000

136,778 SF

Versatile Commercial Property Near Columbia

3.16 acres with 3,000+ sqft building, multiple operational possibilities.

1510 Canal Dr, Columbia, SC 29210

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$1,995,000

4,325 SF

Dental Office in Columbia Corridor

Well-maintained dental office in the SE Columbia corridor.

741 Greenlawn Dr, Columbia, SC

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$230,000

1,650 SF

Medical Office on St. Andrews

Medical office building with high visibility and accessibility.

6148 Saint Andrews Rd, Columbia, SC

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$291,500

2,915 SF

Former Dental Clinic For Rent

2,915 SF former dental clinic available for rent.

392 Saint Andrews Rd, Columbia, SC

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Contact for pricing

12,395 SF

Medical Office Near Medical Campuses

Medical office building with ample parking near medical facilities.

1706 St Julian Pl, Columbia, SC

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$4,800,000

20,000 SF

Class A Medical Office Building

Medical office building for sale in Northeast Columbia, SC.

710 Rabon Rd, Columbia, SC 29203

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Lexington County, SC Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Lexington County, SC, showcased through 32 active listings on our real estate platform. These investment opportunities span a total of 414,424 square feet of properties for sale, with an estimated market value of $52,656,850.

Sale prices for medical spaces in Lexington County, SC start at $169,000, averaging $1,950,253, and reaching up to $7,350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.