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    Lexington County, SC Medical Office Space for Sale

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    39 results
    Renovated Commercial Building in Columbia
    $250,000
    1,138 SF

    Renovated Commercial Building in Columbia

    3201 Broad River Road, Columbia, SC 29210

    Multi-tenant property suitable for retail, medical, or aviation businesses.

    • Excellent location in the heart of Columbia, SC, with easy access to I‑20 and I‑26 and 8 minutes from downtown.
    • Completely renovated in 2014.
    • Multi‑tenant property suitable for retail, medical office, salon, or boutique.
    • Huge parking area with 15 spaces and roundabout driveway.
    • Currently operating as an aviation instructor academy and medical spa with existing infrastructure.
    Updated: Apr 23
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    Lexington Commercial Land For Sale
    $2,750,000
    5.89 Acres

    Lexington Commercial Land For Sale

    206 BO TIRE Way, Lexington, SC 29072

    Pad-ready commercial parcel in high-traffic area, Lexington, SC.

    • Pad‑ready ±5.88‑acre commercial parcel in Publix‑anchored Hendrix Crossing Shopping Center.
    • Located on high‑traffic Hwy 378 corridor with direct access via Bo Tire Way.
    • Fully graded with stormwater infrastructure and all major utilities in place.
    • Zoned Intensive Development (ID) allowing diverse commercial uses.
    • Subdivision potential available.
    Updated: Jan 2
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    Leesville Commercial Land Opportunity
    $275,000
    1.96 Acres

    Leesville Commercial Land Opportunity

    1.96 acres suitable for retail, medical, or office development.

    0 E Church Street, Leesville, SC 29070
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    Medical Office Building For Sale
    $695,000
    4,900 SF

    Medical Office Building For Sale

    4,900 SF medical office building with significant plumbing infrastructure.

    110 Atrium Way, Columbia, SC 29223
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    West Columbia Medical/Office Park
    $7,350,000
    39,722 SF

    West Columbia Medical/Office Park

    Four Class A buildings, 100% occupied, located on Sunset Boulevard.

    3221, 3223, 3225, & 3231 Sunset Blvd., West Columbia, SC 29169
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    Freestanding Medical Office Investment
    $1,250,000
    3,200 SF

    Freestanding Medical Office Investment

    Freestanding medical office building for sale in Northeast Columbia.

    131 Wildewood Park Drive, Columbia, SC 29223
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    High-Visibility Business/Office Center For Sale
    $2,250,000
    15,593 SF

    High-Visibility Business/Office Center For Sale

    Office/retail building with high visibility and customer parking.

    7358 Garners Ferry, Columbia, SC 29209
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    High-Traffic Commercial Center with Suites
    $2,150,000
    15,593 SF

    High-Traffic Commercial Center with Suites

    Highly visible commercial center with 41 suites in Columbia, SC.

    7358 Garners Ferry, Columbia, SC 29209
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    Downtown Office Condos For Sale
    $975,000
    5,528 SF

    Downtown Office Condos For Sale

    Four office condos totaling 5,528 SF in downtown Columbia.

    2757 Laurel St, Columbia, SC
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    Columbia Investment Property For Sale
    $1,798,000
    6,104 SF

    Columbia Investment Property For Sale

    Investment opportunity with a publicly traded tenant in Columbia, SC.

    1840 Pineview Dr, Columbia, SC
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    Medical NNN Investment Opportunity
    $2,190,000
    4,715 SF

    Medical NNN Investment Opportunity

    Single tenant medical property for sale in Lexington, SC.

    125 Park Pl Ct, Lexington, SC 29072
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    Freestanding Office Building For Sale
    Contact for pricing
    4,200 SF

    Freestanding Office Building For Sale

    4,200 SF office building for sale or lease.

    2901 Millwood Ave., Columbia, SC 29205
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    Downtown Columbia Office Building For Sale
    $3,000,000
    45,500 SF

    Downtown Columbia Office Building For Sale

    25,000 SF office building in downtown Columbia.

    950 Taylor St, Columbia, SC 29201
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    Downtown Chapin Commercial Space Available
    $400,000
    1,410 SF

    Downtown Chapin Commercial Space Available

    Commercial space suitable for various businesses in downtown Chapin, SC.

    104 East Boundary Street, Chapin, SC 29036
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    Medical/Office Building Near Lexington Medical
    $1,145,000
    6,300 SF

    Medical/Office Building Near Lexington Medical

    6,300 SF building suitable for medical or traditional office use.

    101 Medical Cir, West Columbia, SC
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    Medical Office Building For Sale
    $1,850,000
    14,442 SF

    Medical Office Building For Sale

    Medical office building with ample parking near medical campuses.

    1701 Saint Julian Pl, Columbia, SC
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    Versatile Commercial Property Near Columbia
    $399,000
    136,778 SF

    Versatile Commercial Property Near Columbia

    3.16 acres with 3,000+ sqft building, multiple operational possibilities.

    1510 Canal Dr, Columbia, SC 29210
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    Office/Medical Building Near Interchange
    $262,350
    2,915 SF

    Office/Medical Building Near Interchange

    2,915 SF office/medical building with ample parking for sale.

    392 St. Andrews Road, Columbia, SC 29210
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    Medical/Office Space in Forest Acres
    $2,050,000
    14,442 SF

    Medical/Office Space in Forest Acres

    Medical/office space available for sale or lease in Columbia.

    1701 St. Julian Place, Columbia, SC 29204
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    Turn-Key Medical Office in Columbia
    $3,150,000
    9,875 SF

    Turn-Key Medical Office in Columbia

    Class A medical office in NE Columbia with flexible layout.

    229 Longtown Rd, Columbia, SC
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    West Columbia Office/Medical Building
    $2,145,000
    12,956 SF

    West Columbia Office/Medical Building

    12,956 SF office/medical building in high-demand corridor.

    3221-3231 Sunset Blvd, West Columbia, SC
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    Columbia Office/Medical Building For Sale
    $3,000,000
    25,000 SF

    Columbia Office/Medical Building For Sale

    Office or medical building with flexible floorplates in Columbia.

    1527 Park St, Columbia, SC
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    West Columbia Medical Office Opportunity
    $4,000,000
    10,840 SF

    West Columbia Medical Office Opportunity

    Medical office building for sale in West Columbia, SC.

    110 Medical Cir, West Columbia, SC 29169
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    Medical Office Condo Near Prisma
    $1,980,000
    22,263 SF

    Medical Office Condo Near Prisma

    Class A medical office condo for sale or lease.

    2113 Adams Grove Rd., Columbia, SC 29203
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    Lexington County, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 303 medical office space for sale in Lexington County, SC, showcased through 39 active listings on our real estate platform. These investment opportunities span a total of 508,748 square feet of properties for sale, with an estimated market value of $62,173,200.

    Sale prices for medical spaces in Lexington County, SC start at $230,000, averaging $1,942,912, and reaching up to $7,350,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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