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    Lancaster, SC
    Medical Premises

    Lancaster, SC Medical Office Space for Sale

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    Two-Building Medical Office Property
    Updated: Dec 1, 2025
    Two-Building Medical Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot
    Two professional buildings on a 0.82‑acre property
    Building 1 includes approximately 14 rooms, reception, waiting, and file areas
    Building 1 has new flooring and a new roof
    Building 2 features three curtained areas and a large open space
    PO Professional Office zoning per the City of Lancaster
    View details
    Medical Office Buildings Near MUSC
    Updated: Jan 26
    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    $975,000
    Prime location minutes from MUSC.
    Two professional office buildings on one property.
    Building 1 is set up as a medical office with 14 rooms and wired for an X‑ray room.
    Zoned "PO" Professional Office by the City of Lancaster.
    New flooring and roof in Building 1.**
    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 44 Potential Opportunities for your consideration. Besides 2 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 37 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Freestanding Office Building
    Freestanding Office Building

    500 Lakeshore Parkway, Rock Hill, SC 29730

    Contact for pricing
    6,560 sqft 1.18 AC lot

    Single-story layout includes private offices, reception areas, conference space, workstations, and on-site parking.

    View details
    Medical Office on Acreage
    Medical Office on Acreage

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1.76 AC lot

    Former dental office with electric heating and air conditioning within Kershaw town limits.

    View details
    Former Medical Office Space
    Former Medical Office Space

    110 South Cleveland Street, Kershaw, SC 29067

    $150,000
    3,550 sqft

    3,350 SF medical office with 11 parking spaces.

    View details
    Freestanding Medical Office Space
    Freestanding Medical Office Space

    611 E Main Street, Rock Hill, SC 29730

    $200,000

    Existing configuration includes a reception area, multiple offices, and a kitchen.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Medical Office Development Land
    Medical Office Development Land

    Charles Hunley Lane, Monroe, NC 28112

    $1,700,000
    7.62 AC lot

    Commercial land within a medical and office park, positioned near major highways, healthcare services, restaurants, and businesses.

    View details

    Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1320 Hwy 9th W Byp
    MEDICAL BUILDING

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

    Estimated value:
    by Request
    1,320 sqft 70.00 AC lot
    View details
    419 Meeting St
    MEDICAL BUILDING

    419 Meeting St, Lancaster, SC 29720-2321

    Estimated value:
    $750,000
    4,600 sqft 22.00 AC lot
    View details
    901 Meeting St
    MEDICAL BUILDING

    901 Meeting St, Lancaster, SC 29720-6200

    Estimated value:
    $740,000
    2,569 sqft
    View details
    1002 Woodland Dr
    MEDICAL BUILDING

    1002 Woodland Dr, Lancaster, SC 29720-1966

    Estimated value:
    $265,000
    3,840 sqft 2.29 AC lot
    View details
    1370 Meeting St
    MEDICAL BUILDING

    1370 Meeting St, Lancaster, SC 29720-2222

    Estimated value:
    $720,000
    7,654 sqft 4.86 AC lot
    View details
    108 Healthcare Dr
    MEDICAL BUILDING

    108 Healthcare Dr, Lancaster, SC 29720-8037

    Estimated value:
    $1,225,000
    5,738 sqft 0.49 AC lot
    View details
    1440 Meeting St
    MEDICAL BUILDING

    1440 Meeting St, Lancaster, SC 29720-2255

    Estimated value:
    $150,000
    2,690 sqft 1.69 AC lot
    View details
    1010 Woodland Dr
    MEDICAL BUILDING

    1010 Woodland Dr, Lancaster, SC 29720-1966

    Estimated value:
    $510,000
    4,705 sqft 5.12 AC lot
    View details
    1228 Colonial Cmns Ct
    MEDICAL BUILDING

    1228 Colonial Cmns Ct, Lancaster, SC 29720-2200

    Estimated value:
    $560,000
    50,800 sqft 2.90 AC lot
    View details
    102 Colonial Ave
    MEDICAL BUILDING

    102 Colonial Ave, Lancaster, SC 29720-1804

    Estimated value:
    $130,000
    2,928 sqft 2.10 AC lot
    View details
    1201 Colonial Cmns Ct
    MEDICAL BUILDING

    1201 Colonial Cmns Ct, Lancaster, SC 29720-2210

    Estimated value:
    $235,000
    3,083 sqft 161.00 AC lot
    View details
    902 Meeting St
    MEDICAL BUILDING

    902 Meeting St, Lancaster, SC 29720-6266

    Estimated value:
    $215,000
    6,006 sqft 1.04 AC lot
    View details
    Wylie St
    MEDICAL BUILDING

    Wylie St, Lancaster, SC 29720

    Estimated value:
    $200,000
    4,665 sqft 138.00 AC lot
    View details
    1130 Hwy 9th W Byp
    MEDICAL BUILDING

    1130 Hwy 9th W Byp, Lancaster, SC 29720-1709

    Estimated value:
    $255,000
    4,387 sqft 1.11 AC lot
    View details
    821 Meeting St
    MEDICAL BUILDING

    821 Meeting St, Lancaster, SC 29720-2201

    Estimated value:
    $160,000
    1,341 sqft 110.00 AC lot
    View details
    134 Rebound Rd
    MEDICAL BUILDING

    134 Rebound Rd, Lancaster, SC 29720-7712

    Estimated value:
    $1,105,000
    17,090 sqft 37.83 AC lot
    View details
    1100 Meeting St
    MEDICAL BUILDING

    1100 Meeting St, Lancaster, SC 29720-2251

    Estimated value:
    $520,000
    11,600 sqft 2.24 AC lot
    View details
    406 Chesterfield Ave
    MEDICAL BUILDING

    406 Chesterfield Ave, Lancaster, SC 29720-3508

    Estimated value:
    $170,000
    4,246 sqft 108.00 AC lot
    View details
    727 Gillsbrook Rd
    MEDICAL BUILDING

    727 Gillsbrook Rd, Lancaster, SC 29720-1817

    Estimated value:
    $110,000
    2,210 sqft 95.00 AC lot
    View details
    1241 Colonial Cmns Ct
    MEDICAL BUILDING

    1241 Colonial Cmns Ct, Lancaster, SC 29720-2210

    Estimated value:
    $195,000
    2,233 sqft 0.63 AC lot
    View details
    1029 Meeting St
    MEDICAL BUILDING

    1029 Meeting St, Lancaster, SC 29720-2205

    Estimated value:
    $460,000
    10,305 sqft 0.18 AC lot
    View details
    1025 Meeting St
    MEDICAL BUILDING

    1025 Meeting St, Lancaster, SC 29720-2204

    Estimated value:
    $755,000
    16,796 sqft 202.00 AC lot
    View details

    Lancaster, SC Medical Office Space Market Trends and Statistics

    Explore 39 medical office space for sale in Lancaster, SC on our real estate platform.

    Sale prices for medical spaces in Lancaster, SC average $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 9
    Medical Office Space 2
    Office Units 2

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29720 $975K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Lancaster County

    New Delisted

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