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    Lancaster, SC
    Medical Premises

    Lancaster, SC Medical Office Space for Sale

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    Waxhaw, NC Fort Lawn, SC Heath Springs, SC Catawba, SC Richburg, SC Edgemoor, SC Great Falls, SC Van Wyck, SC
    Two-Building Professional Office Property
    Updated: Dec 1, 2025
    Two-Building Professional Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot
    Two professional buildings on one property: 1201 and 1203 Colonial Commons Ct
    1201 Colonial Commons Ct set up as a medical office with ~14 rooms, reception, waiting room, and wired for an X‑ray room
    1203 Colonial Commons Ct includes reception and waiting room areas, file room, three curtained areas, large open space, and upper‑level work stations
    PO (Professional Office) zoning per the City of Lancaster zoning chart
    Building 1 received new flooring and a new roof
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    Medical Office Buildings Near MUSC
    Updated: Dec 1, 2025
    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    $975,000
    Prime location minutes from MUSC.
    Two professional office buildings on one property.
    Building 1 is set up as a medical office with 14 rooms and wired for an X‑ray room.
    Zoned "PO" Professional Office by the City of Lancaster.
    New flooring and roof in Building 1.
    View details
    Medical Office Building
    Medical Office Building

    1370 W Meeting Street, Lancaster, SC 29720

    Contact for pricing

    Large medical office building with exam rooms, nurses stations, lab space, and ample parking.

    View details
    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 48 Potential Opportunities for your consideration. Besides 3 Active listings in Lancaster, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 37 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Chiropractic Office Building
    Chiropractic Office Building

    518 North Avenue, Rock Hill, SC 29732

    $850,000
    7,000 sqft

    Former chiropractic clinic offering exam and therapy rooms alongside private offices for flexible medical and office use.

    View details
    Versatile Commercial Property in Rock Hill
    Versatile Commercial Property in Rock Hill

    166 Dotson Street, Rock Hill, SC 29732

    $1,000,000
    10,479 sqft 1.24 AC lot

    10,479 SF commercial property suitable for various uses.

    View details
    Kershaw Office Building on Large Lot
    Kershaw Office Building on Large Lot

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1,100 sqft 1.76 AC lot

    Office building on 1.76 acres in Kershaw, South Carolina.

    View details
    Former Medical Office Space
    Former Medical Office Space

    110 South Cleveland Street, Kershaw, SC 29067

    $150,000
    3,550 sqft

    3,350 SF medical office with 11 parking spaces.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Monroe Commercial Land For Sale
    Monroe Commercial Land For Sale

    Charles Hunley Lane, Monroe, NC 28112

    $1,700,000
    7.62 AC lot

    Commercial land available in high-traffic Monroe location.

    View details
    Harrisburg Land Investment Opportunity
    Harrisburg Land Investment Opportunity

    9201 McCorkle Lane, Charlotte, NC 28215

    $1,600,000
    16.05 AC lot

    16+ acres near Atrium Medical Center, Harrisburg, NC.

    View details
    Highway Frontage Commercial Land
    Highway Frontage Commercial Land

    Tbd Us Hwy 74 None, Wadesboro, NC 28170

    $289,000
    1.00 AC lot

    One acre commercial lot with highway frontage.

    View details
    Whitmire Redevelopment Opportunity
    Whitmire Redevelopment Opportunity

    6470 Whitmire Highway, Whitmire, SC 29178

    $75,000
    3.43 AC lot

    3.43 acre commercial tract ideal for redevelopment.

    View details

    Off-Market Properties in Lancaster, SC

    Consider similar Off-Market properties in Lancaster, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1320 Hwy 9th W Byp
    MEDICAL BUILDING

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

    Value Estimation by Request
    1,320 sqft 70.00 AC lot
    View details
    419 Meeting St
    MEDICAL BUILDING

    419 Meeting St, Lancaster, SC 29720-2321

    $750,000
    Estimated value
    4,600 sqft 22.00 AC lot
    View details
    901 Meeting St
    MEDICAL BUILDING

    901 Meeting St, Lancaster, SC 29720-6200

    $785,000
    Estimated value
    2,569 sqft
    View details
    1002 Woodland Dr
    MEDICAL BUILDING

    1002 Woodland Dr, Lancaster, SC 29720-1966

    Value Estimation by Request
    3,840 sqft 2.29 AC lot
    View details
    1370 Meeting St
    MEDICAL BUILDING

    1370 Meeting St, Lancaster, SC 29720-2222

    $725,000
    Estimated value
    7,654 sqft 4.86 AC lot
    View details
    108 Healthcare Dr
    MEDICAL BUILDING

    108 Healthcare Dr, Lancaster, SC 29720-8037

    $1,230,000
    Estimated value
    5,738 sqft 0.49 AC lot
    View details
    1440 Meeting St
    MEDICAL BUILDING

    1440 Meeting St, Lancaster, SC 29720-2255

    Value Estimation by Request
    2,690 sqft 1.69 AC lot
    View details
    1010 Woodland Dr
    MEDICAL BUILDING

    1010 Woodland Dr, Lancaster, SC 29720-1966

    Value Estimation by Request
    4,705 sqft 5.12 AC lot
    View details
    1228 Colonial Cmns Ct
    MEDICAL BUILDING

    1228 Colonial Cmns Ct, Lancaster, SC 29720-2200

    $2,880,000
    Estimated value
    50,800 sqft 2.90 AC lot
    View details
    102 Colonial Ave
    MEDICAL BUILDING

    102 Colonial Ave, Lancaster, SC 29720-1804

    Value Estimation by Request
    2,928 sqft 2.10 AC lot
    View details
    1201 Colonial Cmns Ct
    MEDICAL BUILDING

    1201 Colonial Cmns Ct, Lancaster, SC 29720-2210

    Value Estimation by Request
    3,083 sqft 161.00 AC lot
    View details
    902 Meeting St
    MEDICAL BUILDING

    902 Meeting St, Lancaster, SC 29720-6266

    Value Estimation by Request
    6,006 sqft 1.04 AC lot
    View details
    Wylie St
    MEDICAL BUILDING

    Wylie St, Lancaster, SC 29720

    Value Estimation by Request
    4,665 sqft 138.00 AC lot
    View details
    1130 Hwy 9th W Byp
    MEDICAL BUILDING

    1130 Hwy 9th W Byp, Lancaster, SC 29720-1709

    Value Estimation by Request
    4,387 sqft 1.11 AC lot
    View details
    821 Meeting St
    MEDICAL BUILDING

    821 Meeting St, Lancaster, SC 29720-2201

    Value Estimation by Request
    1,341 sqft 110.00 AC lot
    View details
    134 Rebound Rd
    MEDICAL BUILDING

    134 Rebound Rd, Lancaster, SC 29720-7712

    $1,105,000
    Estimated value
    17,090 sqft 37.83 AC lot
    View details
    1100 Meeting St
    MEDICAL BUILDING

    1100 Meeting St, Lancaster, SC 29720-2251

    $520,000
    Estimated value
    11,600 sqft 2.24 AC lot
    View details
    406 Chesterfield Ave
    MEDICAL BUILDING

    406 Chesterfield Ave, Lancaster, SC 29720-3508

    Value Estimation by Request
    4,246 sqft 108.00 AC lot
    View details
    727 Gillsbrook Rd
    MEDICAL BUILDING

    727 Gillsbrook Rd, Lancaster, SC 29720-1817

    Value Estimation by Request
    2,210 sqft 95.00 AC lot
    View details
    1241 Colonial Cmns Ct
    MEDICAL BUILDING

    1241 Colonial Cmns Ct, Lancaster, SC 29720-2210

    Value Estimation by Request
    2,233 sqft 0.63 AC lot
    View details
    1029 Meeting St
    MEDICAL BUILDING

    1029 Meeting St, Lancaster, SC 29720-2205

    Value Estimation by Request
    10,305 sqft 0.18 AC lot
    View details

    Lancaster, SC Medical Office Space Market Trends and Statistics

    Explore 40 medical office space for sale in Lancaster, SC, showcased through 3 active listings on our real estate platform.

    Sale prices for medical spaces in Lancaster, SC average $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office buildings 6
    Office Units 4
    Medical Office Space 3

    Demographics Overview

    Population 52K
    Population Growth (5Y) +8.0%
    Median Household Income $59,039
    College Educated 9.5%

    High-Yield Neighborhoods for Investment

    Identify Lancaster submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    29720 $975K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Lancaster County

    New Delisted

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