Greenville County, SC Medical Office Space for sale

Updated: Apr 20

Single-Level Brick Medical Office

203 S Weston Street, Fountain Inn, SC 29644

$1,500,000

0.59 AC lot

Medical office property at 201 and 203 S Weston Street
C‑1 zoning with 0.59 acres included
Single‑level brick building built in the 1950s
Adjacent lot provides over 30 parking spaces
24x24 brick outbuilding included

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Updated: Jul 13

Absolute NNN Dental Office

1173 Ashmore Bridge Rd, Greenville, SC 29605

Contact for pricing

4,200 sqft

Newly delivered 4,200 SF dental office built in 2026
Absolute NNN lease structure with zero landlord responsibilities
12‑year lease term commencing June 2026
Lease includes 10% rental increases at Year 6 and Year 11 and throughout all option periods
Full corporate guarantee from Heartland Dental

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Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing

7,880 sqft

Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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Medical Office with Basement

202 Memorial Drive, Greer, SC 29650

Contact for pricing

1,144 sqft 0.34 AC lot

The property includes on-site parking and additional basement area for potential office conversion.

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Medical Office with Parking

21 Memorial Medical Dr, Greenville, SC 29605

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3,400 sqft 0.50 AC lot

Former dermatology practice with dedicated parking near I-85 and Faris Road.

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All-Brick Medical Office Building

3115 Brushy Creek Rd, Greer, SC 29650

Contact for pricing

6,244 sqft

All-brick medical office building in a professional office park with a 10-year leaseback.

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Single-Tenant Medical Office Building

13 Edgewood Dr, Greenville, SC 29605

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Fully leased orthopedic outpatient clinic building used by Prisma Health.

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 7 Active listings in Greenville County, SC, we suggest exploring several alternatives: similar 65 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cleared Commercial Land

4 Aaron Tippin Drive, Greer, SC 29650

$194,000

0.87 AC lot

Level OP-zoned site with public water and sewer available for office, medical, and professional development.

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Prime Land in Greenville, SC

3900 Highway 153, Greenville, SC 29611

$1,800,000

10.91 AC lot

11+/- acre property ideal for development in a growing corridor.

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Commercial Land with Shared Parking

29 Civic Center Boulevard, Anderson, SC 29625

Contact for pricing

0.15 AC lot

Commercial lot with shared parking, exterior lighting, and high-speed internet access.

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Commercial Lot with Shared Parking

29 Civic Center Boulevard, Anderson, SC 29625

Contact for pricing

0.15 AC lot

Commercial site with shared parking, exterior lighting, public water, and high-speed internet access.

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Off-Market Properties in Greenville County, SC

Consider similar Off-Market properties in Greenville County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

MEDICAL BUILDING

Value Estimation by Request

0.74 AC lot

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MEDICAL BUILDING

6704 White Horse Rd, Greenville, SC 29611-2504

$1,555,000

Estimated value

0.74 AC lot

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DENTAL BUILDING

155 Halton Vlg Cir, Greenville, SC 29607-6825

$345,000

Estimated value

0.19 AC lot

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MEDICAL BUILDING

141 Halton Vlg Cir, Greenville, SC 29607-6825

$2,160,000

Estimated value

0.29 AC lot

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DENTAL BUILDING

100 Woodruff Pl Cir, Simpsonville, SC 29681-3672

$1,280,000

Estimated value

0.06 AC lot

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MEDICAL BUILDING

812 Wade Hampton Blvd, Greer, SC 29650-1309

$315,000

Estimated value

0.40 AC lot

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Greenville County, SC Medical Office Space Market Trends and Statistics

Explore 72 medical office space for sale in Greenville County, SC, showcased through 7 active listings on our real estate platform. These investment opportunities span a total of 22,868 square feet of properties for sale, with an estimated market value of $1,500,000.

Sale prices for medical spaces in Greenville County, SC average $1,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Featured Greenville County Real Estate Agencies

Realmo connects you with licensed Greenville County CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

Keller Williams Greenville Upstate

403 Woods Lake Rd Greenville, SC 29607

Phone: 18642347500

www.kwgreenvillesc.com

BlackStream International Real Estate

20 Overbrook Court, Suite 400 Greenville, SC 29607

Phone: 18645531998

www.blackstreaminternational.com

Coldwell Banker Caine

111 Williams Street Greenville, SC 29601

Phone: 18642502800

cbcaine.com