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    Lancaster County, SC Medical Office Space for Sale

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    Columbia, SC Greenville, SC Spartanburg, SC
    6 results
    Kershaw Office Building on Large Lot
    $200,000
    1,100 SF
    Kershaw Office Building on Large Lot

    104 S Ashe Street, Kershaw, SC 29067

    Office building on 1.76 acres in Kershaw, South Carolina.
    • Large 1.76 acre lot (2 lot parcel) within town limits
    • Potential for rezoning to residential and remodeling into a home
    • Existing 1100+ sq ft building suitable for office use
    • Located in a doctor care area
    • 'Easy walking' within city limits
    Updated: May 4
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    Two Professional Buildings Near MUSC
    $975,000
    0.82 Acres
    Two Professional Buildings Near MUSC

    1201 Colonial Commons Court, Lancaster, SC 29720

    Two professional office buildings near MUSC in Lancaster, South Carolina.
    • Prime location minutes from MUSC (Medical University of South Carolina).
    • Two professional office buildings on one property.
    • Zoned "PO" Professional Office by the City of Lancaster.
    • Building 1 features a medical office layout with 14 rooms and a wired X‑ray room.
    • New flooring and new roof installed in Building 1.
    Updated: Dec 1, 2025
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    Medical Office Buildings Near MUSC
    $975,000
    Medical Office Buildings Near MUSC

    Two professional buildings suitable for medical or office use.

    1201 Colonial Commons Ct, Lancaster, SC 29720

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    Former Medical Office Space
    $150,000
    3,550 SF
    Former Medical Office Space

    3,350 SF medical office with 11 parking spaces.

    110 South Cleveland Street, Kershaw, SC 29067

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    Lancaster Medical/Office Space Available
    $875,000
    6,900 SF
    Lancaster Medical/Office Space Available

    Versatile space near MUSC Health Lancaster Medical Center.

    980 N Woodland Dr, Lancaster, SC

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    12.4 Acres Assemblage in Indian Land
    Contact for pricing
    12.40 Acres
    12.4 Acres Assemblage in Indian Land

    12.4 acres in Indian Land, South Carolina for sale.

    Charlotte Hwy, Indian Land, SC 29707

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    Based on your search, we've compiled 61 Potential Opportunities for your consideration. Besides 6 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 51 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Monroe Commercial Land For Sale
    $1,700,000
    7.62 Acres
    Monroe Commercial Land For Sale

    Commercial land available in high-traffic Monroe location.

    Charles Hunley Lane, Monroe, NC 28112

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    Commercial Land Near Future Development
    Contact for pricing
    8.00 Acres
    Commercial Land Near Future Development

    Commercial land near proposed residential development with multiple uses.

    2299 Mancke Dr, Rock Hill, SC 29732

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    Harrisburg Land Investment Opportunity
    $1,600,000
    16.05 Acres
    Harrisburg Land Investment Opportunity

    16+ acres near Atrium Medical Center, Harrisburg, NC.

    9201 McCorkle Lane, Charlotte, NC 28215

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    Commercial Lot on Hwy 74
    $289,000
    1.00 Acre
    Commercial Lot on Hwy 74

    One-acre commercial lot with high traffic and development potential.

    Tbd Us Hwy 74 None W, Wadesboro, NC 28170

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    Off-Market Properties in Lancaster County, SC

    Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1320 Hwy 9th W Byp
    MEDICAL BUILDING
    1,320 SF Lot: 70.00 Acres
    Value Estimation by Request

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

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    419 Meeting St
    MEDICAL BUILDING
    4,600 SF Lot: 22.00 Acres
    Estimated value
    $750,000

    419 Meeting St, Lancaster, SC 29720-2321

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    2536 Lengers Way
    MEDICAL BUILDING
    14,375 SF Lot: 3.60 Acres
    Estimated value
    $785,000

    2536 Lengers Way, Indian Land, SC 29707-7126

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    901 Meeting St
    MEDICAL BUILDING
    2,569 SF
    Estimated value
    $785,000

    901 Meeting St, Lancaster, SC 29720-6200

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    110 Cleveland St
    MEDICAL BUILDING
    4,110 SF Lot: 55.00 Acres
    Value Estimation by Request

    110 Cleveland St, Kershaw, SC 29067-1403

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    1002 Woodland Dr
    MEDICAL BUILDING
    3,840 SF Lot: 2.29 Acres
    Value Estimation by Request

    1002 Woodland Dr, Lancaster, SC 29720-1966

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    7666 Charlotte Hwy
    MEDICAL BUILDING
    22,198 SF Lot: 5.58 Acres
    Estimated value
    $1,275,000

    7666 Charlotte Hwy, Indian Land, SC 29707-7000

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    1370 Meeting St
    MEDICAL BUILDING
    7,654 SF Lot: 4.86 Acres
    Estimated value
    $725,000

    1370 Meeting St, Lancaster, SC 29720-2222

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    108 Healthcare Dr
    MEDICAL BUILDING
    5,738 SF Lot: 0.49 Acres
    Estimated value
    $1,230,000

    108 Healthcare Dr, Lancaster, SC 29720-8037

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    1440 Meeting St
    MEDICAL BUILDING
    2,690 SF Lot: 1.69 Acres
    Value Estimation by Request

    1440 Meeting St, Lancaster, SC 29720-2255

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    108 Cleveland St
    MEDICAL BUILDING
    2,310 SF Lot: 55.00 Acres
    Value Estimation by Request

    108 Cleveland St, Kershaw, SC 29067-1403

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    1010 Woodland Dr
    MEDICAL BUILDING
    4,705 SF Lot: 5.12 Acres
    Value Estimation by Request

    1010 Woodland Dr, Lancaster, SC 29720-1966

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    212 Marion St
    MEDICAL BUILDING
    3,360 SF Lot: 96.00 Acres
    Value Estimation by Request

    212 Marion St, Kershaw, SC 29067-1442

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    1228 Colonial Cmns Ct
    MEDICAL BUILDING
    50,800 SF Lot: 2.90 Acres
    Estimated value
    $2,880,000

    1228 Colonial Cmns Ct, Lancaster, SC 29720-2200

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    102 Colonial Ave
    MEDICAL BUILDING
    2,928 SF Lot: 2.10 Acres
    Value Estimation by Request

    102 Colonial Ave, Lancaster, SC 29720-1804

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    1201 Colonial Cmns Ct
    MEDICAL BUILDING
    3,083 SF Lot: 161.00 Acres

    1201 Colonial Cmns Ct, Lancaster, SC 29720-2210

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    902 Meeting St
    MEDICAL BUILDING
    6,006 SF Lot: 1.04 Acres
    Value Estimation by Request

    902 Meeting St, Lancaster, SC 29720-6266

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    Wylie St
    MEDICAL BUILDING
    4,665 SF Lot: 138.00 Acres
    Value Estimation by Request

    Wylie St, Lancaster, SC 29720

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    Lancaster County, SC Medical Office Space Investment Opportunities Market Analysis

    Explore 57 medical office space for sale in Lancaster County, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 11,550 square feet of properties for sale, with an estimated market value of $1,225,000.

    Sale prices for medical spaces in Lancaster County, SC start at $150,000, averaging $408,333, and reaching up to $875,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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