Lancaster County, SC Medical Office Space for sale

Updated: May 4

Kershaw Office Building on Large Lot

104 S Ashe Street, Kershaw, SC 29067

$200,000

1,100 sqft 1.76 AC lot

Large 1.76 acre lot (2 lot parcel) within town limits
Potential for rezoning to residential and remodeling into a home
Existing 1100+ sq ft building suitable for office use
Located in a doctor care area
'Easy walking' within city limits

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Updated: Dec 1, 2025

Professional Office Duplex Opportunity

1201 Colonial Commons Court, Lancaster, SC 29720

$975,000

0.82 AC lot

Two professional office buildings on one property at 1201 and 1203 Colonial Commons Ct
Building 1 (1201 Colonial Commons Ct) set up as a medical office with about 14 rooms, reception, waiting room, and separate file room
Building 1 includes an upper level work area and is wired for an X‑ray room
Building 2 (1203 Colonial Commons Ct) features three curtained areas, reception, waiting room, file room, large open space, and upper‑level work stations
Building 1 has new flooring and a new roof; both buildings use central heating and central air

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Former Medical Office Space

110 South Cleveland Street, Kershaw, SC 29067

$150,000

3,550 sqft

3,350 SF medical office with 11 parking spaces.

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Medical Office Buildings Near MUSC

1201 Colonial Commons Ct, Lancaster, SC 29720

$975,000

Two professional buildings suitable for medical or office use.

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Based on your search, we've compiled 59 Potential Opportunities for your consideration. Besides 4 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 51 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Monroe Commercial Land For Sale

Charles Hunley Lane, Monroe, NC 28112

$1,700,000

7.62 AC lot

Commercial land available in high-traffic Monroe location.

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Commercial Land Near Future Development

2299 Mancke Dr, Rock Hill, SC 29732

Contact for pricing

8.00 AC lot

Commercial land near proposed residential development with multiple uses.

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Highway Frontage Commercial Land

Tbd Us Hwy 74 None, Wadesboro, NC 28170

$289,000

1.00 AC lot

One acre commercial lot with highway frontage.

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Harrisburg Land Investment Opportunity

9201 McCorkle Lane, Charlotte, NC 28215

$1,600,000

16.05 AC lot

16+ acres near Atrium Medical Center, Harrisburg, NC.

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Off-Market Properties in Lancaster County, SC

Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.