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    Lancaster County, SC Medical Office Space for Sale

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    Kershaw Office Building on Large Lot
    Updated: May 4
    Kershaw Office Building on Large Lot

    104 S Ashe Street, Kershaw, SC 29067

    $200,000
    1,100 sqft 1.76 AC lot
    Large 1.76 acre lot (2 lot parcel) within town limits
    Potential for rezoning to residential and remodeling into a home
    Existing 1100+ sq ft building suitable for office use
    Located in a doctor care area
    'Easy walking' within city limits
    View details
    Two-Building Medical Office Property
    Updated: Dec 1, 2025
    Two-Building Medical Office Property

    1201 Colonial Commons Court, Lancaster, SC 29720

    $975,000
    0.82 AC lot
    Two professional buildings on a 0.82‑acre property
    Building 1 includes approximately 14 rooms, reception, waiting, and file areas
    Building 1 has new flooring and a new roof
    Building 2 features three curtained areas and a large open space
    PO Professional Office zoning per the City of Lancaster
    View details
    Former Medical Office Space
    Former Medical Office Space

    110 South Cleveland Street, Kershaw, SC 29067

    $150,000
    3,550 sqft

    3,350 SF medical office with 11 parking spaces.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Medical Office Buildings Near MUSC
    Medical Office Buildings Near MUSC

    1201 Colonial Commons Ct, Lancaster, SC 29720

    $975,000

    Two professional buildings suitable for medical or office use.

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    Medical Office Building
    Medical Office Building

    1370 W Meeting Street, Lancaster, SC 29720

    Contact for pricing

    Large medical office building with exam rooms, nurses stations, lab space, and ample parking.

    View details
    Based on your search, we've compiled 57 Potential Opportunities for your consideration. Besides 5 Active listings in Lancaster County, SC, we suggest exploring several alternatives: similar 51 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Medical Office Development Land
    Medical Office Development Land

    Charles Hunley Lane, Monroe, NC 28112

    $1,700,000
    7.62 AC lot

    Commercial land within a medical and office park, positioned near major highways, healthcare services, restaurants, and businesses.

    View details

    Off-Market Properties in Lancaster County, SC

    Consider similar Off-Market properties in Lancaster County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1320 Hwy 9th W Byp
    MEDICAL BUILDING

    1320 Hwy 9th W Byp, Lancaster, SC 29720-4712

    Value Estimation by Request
    1,320 sqft 70.00 AC lot
    View details
    419 Meeting St
    MEDICAL BUILDING

    419 Meeting St, Lancaster, SC 29720-2321

    $750,000
    Estimated value
    4,600 sqft 22.00 AC lot
    View details
    2536 Lengers Way
    MEDICAL BUILDING

    2536 Lengers Way, Indian Land, SC 29707-7126

    $470,000
    Estimated value
    14,375 sqft 3.60 AC lot
    View details
    901 Meeting St
    MEDICAL BUILDING

    901 Meeting St, Lancaster, SC 29720-6200

    $740,000
    Estimated value
    2,569 sqft
    View details
    110 Cleveland St
    MEDICAL BUILDING

    110 Cleveland St, Kershaw, SC 29067-1403

    $625,000
    Estimated value
    4,110 sqft 55.00 AC lot
    View details
    1002 Woodland Dr
    MEDICAL BUILDING

    1002 Woodland Dr, Lancaster, SC 29720-1966

    $265,000
    Estimated value
    3,840 sqft 2.29 AC lot
    View details
    7666 Charlotte Hwy
    MEDICAL BUILDING

    7666 Charlotte Hwy, Indian Land, SC 29707-7000

    $860,000
    Estimated value
    22,198 sqft 5.58 AC lot
    View details
    1370 Meeting St
    MEDICAL BUILDING

    1370 Meeting St, Lancaster, SC 29720-2222

    $720,000
    Estimated value
    7,654 sqft 4.86 AC lot
    View details
    108 Healthcare Dr
    MEDICAL BUILDING

    108 Healthcare Dr, Lancaster, SC 29720-8037

    $1,225,000
    Estimated value
    5,738 sqft 0.49 AC lot
    View details
    1440 Meeting St
    MEDICAL BUILDING

    1440 Meeting St, Lancaster, SC 29720-2255

    $150,000
    Estimated value
    2,690 sqft 1.69 AC lot
    View details
    108 Cleveland St
    MEDICAL BUILDING

    108 Cleveland St, Kershaw, SC 29067-1403

    $285,000
    Estimated value
    2,310 sqft 55.00 AC lot
    View details
    1010 Woodland Dr
    MEDICAL BUILDING

    1010 Woodland Dr, Lancaster, SC 29720-1966

    $510,000
    Estimated value
    4,705 sqft 5.12 AC lot
    View details
    212 Marion St
    MEDICAL BUILDING

    212 Marion St, Kershaw, SC 29067-1442

    $130,000
    Estimated value
    3,360 sqft 96.00 AC lot
    View details
    1228 Colonial Cmns Ct
    MEDICAL BUILDING

    1228 Colonial Cmns Ct, Lancaster, SC 29720-2200

    $560,000
    Estimated value
    50,800 sqft 2.90 AC lot
    View details
    102 Colonial Ave
    MEDICAL BUILDING

    102 Colonial Ave, Lancaster, SC 29720-1804

    $130,000
    Estimated value
    2,928 sqft 2.10 AC lot
    View details
    1201 Colonial Cmns Ct
    MEDICAL BUILDING

    1201 Colonial Cmns Ct, Lancaster, SC 29720-2210

    $235,000
    Estimated value
    3,083 sqft 161.00 AC lot
    View details
    902 Meeting St
    MEDICAL BUILDING

    902 Meeting St, Lancaster, SC 29720-6266

    $215,000
    Estimated value
    6,006 sqft 1.04 AC lot
    View details
    Wylie St
    MEDICAL BUILDING

    Wylie St, Lancaster, SC 29720

    $200,000
    Estimated value
    4,665 sqft 138.00 AC lot
    View details
    501 Matson St
    MEDICAL BUILDING

    501 Matson St, Kershaw, SC 29067-1011

    $320,000
    Estimated value
    4,560 sqft 1.14 AC lot
    View details

    Lancaster County, SC Medical Office Space Market Trends and Statistics

    Explore 56 medical office space for sale in Lancaster County, SC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 4,650 square feet of properties for sale, with an estimated market value of $2,300,000.

    Sale prices for medical spaces in Lancaster County, SC start at $150,000, averaging $575,000, and reaching up to $975,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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