For Sale
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Office
1
  • Retail
  • Office
  • Residential Income
  • Restaurants
  • Industrial
  • Mixed-Use
  • Hospitality
  • Health Care
  • Sports & Entertainment
  • Land
  • Agricultural
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

West Seneca, NY Live-work Space for Sale

Notify Me
List
Map
Manufacturing Facility with Apartment
$498,000
20,400 SF

Manufacturing Facility with Apartment

1336 Genesee Street, Buffalo, NY 14211

20,400 SF manufacturing facility with apartment and expansion potential.

  • 15,800 SF Manufacturing/Warehouse Space in Opportunity Zone
  • Unique Second Floor One‑Bedroom Apartment with Private Rooftop Deck (Convertible to Offices)
  • Multiple Overhead Doors: Three 12' and Three 14'
  • Hoists Included: One Ton, Two Ton, and Half Ton
  • 20,400 SF Total Building Size with 3200 SF Second Floor Storage
Updated: Nov 21, 2025
View details
Downtown Buffalo Mixed-Use Building
$850,000
13,000 SF

Downtown Buffalo Mixed-Use Building

515-517 Main Street, Buffalo, NY 14203

13,000 SF building in the heart of downtown Buffalo.

  • 13,000 sf building in the heart of downtown Buffalo
  • Located in the quickly developing 500 block
  • Suitable for retail, apartment conversion, or live/work
  • Rare opportunity
  • Part of Buffalo’s renaissance
Updated: Nov 21, 2025
View details
Based on your search, we've compiled 35 Potential Opportunities for your consideration. Besides 2 Active listings in West Seneca, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 25 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Prime Mixed-Use Redevelopment Opportunity
$319,900
3,027 SF

Prime Mixed-Use Redevelopment Opportunity

Mixed-use property in vibrant Rochester corridor, ready for redevelopment.

606 Monroe Avenue, Rochester, NY 14607
View details
Mixed-Use Property in Center City District
$199,999
4,331 SF

Mixed-Use Property in Center City District

Mixed-use property with residential income potential in Rochester, NY.

416 Central Avenue, Rochester, NY 14605
View details
Mixed-Use Property with Commercial Space
$174,900
2,064 SF

Mixed-Use Property with Commercial Space

Versatile property with commercial space and residential apartment.

624 Black River Boulevard N, Rome, NY 13440
View details
Commercial Laundromat with Apartment
$380,000
2,400 SF

Commercial Laundromat with Apartment

Turnkey laundromat business with a well-maintained apartment.

745 Erie Blvd W, Rome, NY 13440
View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Amherst Development Opportunity
$800,000
0.65 Acres

Prime Amherst Development Opportunity

0.65 acre commercial lot in a high-traffic area.

220 Meyer Road, Buffalo, NY 14226
View details
Spacious Commercial Building on M-65
$480,000
5,500 SF

Spacious Commercial Building on M-65

Large commercial building with living space on heavily traveled M-65.

4271 N M-65, Hale, MI 48739
View details
Philadelphia Land Opportunity
$37,000
0.02 Acres

Philadelphia Land Opportunity

Two adjacent lots available for purchase in Philadelphia, PA.

5423 MARKET Street, Philadelphia, PA 19139
View details
Mixed-Use Property Near Temple
$200,000
0.02 Acres

Mixed-Use Property Near Temple

Mixed-use property with business and living space near Temple University.

1538 W SEYBERT Street, Philadelphia, PA 19121
View details

Explore Off-Market Properties in West Seneca, NY

Consider similar Off-Market properties in West Seneca, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

780 Main St

780 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 2,308 SF
Value Estimation by Request
780 Main St, West Seneca, NY 14224-3126
View details
735 Un Rd

735 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,827 SF
Value Estimation by Request
735 Un Rd, West Seneca, NY 14224-3422
View details
1370 Un Rd

1370 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 3,301 SF
Value Estimation by Request
1370 Un Rd, West Seneca, NY 14224-2957
View details
979 Un Rd

979 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 5,391 SF
Value Estimation by Request
979 Un Rd, West Seneca, NY 14224-3491
View details
1363 Un Rd

1363 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,916 SF
Value Estimation by Request
1363 Un Rd, West Seneca, NY 14224-2918
View details
66 Weiss Ave

66 Weiss Ave

OFFICE/RESIDENTIAL (MIXED USE) • 1,528 SF
Value Estimation by Request
66 Weiss Ave, West Seneca, NY 14224-4632
View details
636 Main St

636 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 3,881 SF
Value Estimation by Request
636 Main St, West Seneca, NY 14224-3052
View details
1293 Un Rd

1293 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 7,452 SF
Value Estimation
$520,000
1293 Un Rd, West Seneca, NY 14224-2941
View details
1167 Un Rd

1167 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 6,000 SF
Value Estimation
$615,000
1167 Un Rd, West Seneca, NY 14224-2932
View details
1364 Un Rd

1364 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,595 SF
Value Estimation by Request
1364 Un Rd, West Seneca, NY 14224-2919
View details
1395 Un Rd

1395 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,482 SF
Value Estimation by Request
1395 Un Rd, West Seneca, NY 14224-2938
View details
2040 Un Rd, Unit 2048

2040 Un Rd, Unit 2048

OFFICE/RESIDENTIAL (MIXED USE) • 4,844 SF
Value Estimation
$725,000
2040 Un Rd, West Seneca, NY 14224-1451
View details
1389 Un Rd

1389 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,052 SF
Value Estimation by Request
1389 Un Rd, West Seneca, NY 14224-2936
View details
1889 Un Rd

1889 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,416 SF
Value Estimation by Request
1889 Un Rd, West Seneca, NY 14224-2065
View details
1413 Un Rd

1413 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,632 SF
Value Estimation by Request
1413 Un Rd, West Seneca, NY 14224-2936
View details
1412 Un Rd

1412 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 3,304 SF
Value Estimation by Request
1412 Un Rd, West Seneca, NY 14224-2948
View details
1888 Un Rd

1888 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 1,541 SF
Value Estimation by Request
1888 Un Rd, West Seneca, NY 14224-2015
View details
2233 Un Rd

2233 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,031 SF
Value Estimation by Request
2233 Un Rd, West Seneca, NY 14224-1441
View details
425 Main St

425 Main St

OFFICE/RESIDENTIAL (MIXED USE) • 2,659 SF
Value Estimation by Request
425 Main St, West Seneca, NY 14224-2822
View details
1909 Un Rd

1909 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,739 SF
Value Estimation by Request
1909 Un Rd, West Seneca, NY 14224-2013
View details
1425 Un Rd

1425 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 3,202 SF
Value Estimation by Request
1425 Un Rd, West Seneca, NY 14224-2936
View details
2034 Un Rd

2034 Un Rd

OFFICE/RESIDENTIAL (MIXED USE) • 2,669 SF
Value Estimation by Request
2034 Un Rd, West Seneca, NY 14224-1451
View details

West Seneca, NY Live-Work Space Investment Opportunities Market Analysis

Explore 27 live-work space for sale in West Seneca, NY on our real estate platform. These investment opportunities span a total of 265,638 square feet of properties for sale, with an estimated market value of $5,745,000.

Sale prices for live-work properties in West Seneca, NY start at $100,000, averaging $287,250, and reaching up to $440,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

List
Map

Property Size Breakdown

Most commercial real estate listings in West Seneca range 100,000+ sqft.

New Listings Trend, 12 Mo

Number of new listings by month over the past year in West Seneca.

Leading Commercial Asset Segments

Office Units 7
Medical Office Space 3
Office buildings 2
Coworking space 1

Top Neighborhoods for Investment

Discover the areas of West Seneca with the highest concentration of for-sale assets and compare their average market prices.

Neighborhood Price Range Average Price
Buffalo - 14224 $325K - 354.9K $340K

Need Help?

Reach out if you need assistance with Realmo tools or have questions about your listings