Winnsboro, SC Commercial Real Estate for Lease

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Former Restaurant on Highway 321
Updated: Nov 21, 2025
Former Restaurant on Highway 321

195 U.S. 321 Bypass, Winnsboro, SC 29180

Contact for pricing
2,393 sqft
Free‑standing QSR building, formerly a Burger King.
Outparcel to KJ's grocery store.
Located on Hwy 321 in Winnsboro, SC.
Available for sale or lease.
Near national retailers including KFC, Pizza Hut, and McDonald's.
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Food Lion Anchored Retail Center
Updated: Aug 18, 2021
Food Lion Anchored Retail Center

1126 US-321 BUS, Winnsboro, SC 29180

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Food Lion anchored center
Great access
High visibility
Located at the entrance to Winnsboro
Access from both US Hwy 321 Bypass and US Hwy 321 Business South
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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 2 Active listings in Winnsboro, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 9 Properties for Sales.

Commercial real estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space for Lease
Retail Space for Lease

420 McNulty Street, Blythewood, SC 29016

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Retail space is available for lease, positioned off I-77 at the same exit as a nearby manufacturing facility.

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Executive Office Suite with Conference Rooms
Executive Office Suite with Conference Rooms

1131 Northpoint Boulevard, Blythewood, SC 29016

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Executive office suites with private exterior offices, reception space, and conference rooms for flexible teams.

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Industrial Land Off Interstate
Industrial Land Off Interstate

30 Commerce Blvd, Ridgeway, SC 29130

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3.21 AC lot

Industrial land site in Fairfield County, positioned just off Interstate 77 with 24-hour ground access to much of the U.S.

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Prime Land in Fairfield County
Prime Land in Fairfield County

30 Commerce Blvd, Ridgeway, SC 29130

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Strategically located land in central South Carolina, near Interstate 77.

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Similar Spaces for Sale in Winnsboro, SC

Consider Similar Space for Sale. We found 9 Spaces matching your search parameters.

Automotive Repair Shop
Automotive Repair Shop

151 Columbia Road, Winnsboro, SC 29180

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1,680 sqft 1.00 AC lot

Leased automotive repair facility with a metal building, secured yard, office entry, and multiple commercial access routes.

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Retail Storefront Building
Retail Storefront Building

314 S Congress Street, Winnsboro, SC 29150

$89,500
1,980 sqft 0.22 AC lot

Retail building with partial tenant occupancy, offering additional space and C1 zoning for compatible commercial uses.

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Agricultural Land with Barndominium
Agricultural Land with Barndominium

529 Martin Road, Winnsboro, SC 29180

$1,850,000
148.22 AC lot

Pastures, stocked ponds, timberland, and a barndominium create a mixed rural property.

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Winnsboro Commercial Property For Sale
Winnsboro Commercial Property For Sale

1132 Kincaid Brg Rd, Winnsboro, SC

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30,108 sqft 3.41 AC lot

Commercial property featuring office, warehouse, and storefront spaces for sale.

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Bed & Breakfast and Event Facility
Bed & Breakfast and Event Facility

600 S Congress St, Winnsboro, SC 29180

Contact for pricing
9,350 sqft 64.00 AC lot

Freestanding hospitality property with 15 guest suites, event spaces, and conference rooms on expansive grounds.

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Rented Multi-Building Portfolio
Rented Multi-Building Portfolio

1712 US-321, Winnsboro, SC 29180

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20.00 AC lot

Five income-producing buildings sit on 20 acres, with the option to buy individually or as a whole.

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Downtown Winnsboro Retail/Office Building
Downtown Winnsboro Retail/Office Building

401 N Congress St, Winnsboro, SC 29180

Contact for pricing
2,265 sqft

Retail/office building for sale in downtown Winnsboro.

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Industrial Land on Highway Corridor
Industrial Land on Highway Corridor

SC Hwy 34, Winnsboro, SC 29180

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130.00 AC lot

130-acre I-1 industrial land tract on Hwy 34 with utilities available and road frontage for potential out-parcels.

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For-Sale Retail Property
For-Sale Retail Property

1023 US-321, Winnsboro, SC 29180

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Retail property offered for sale, with a stated 7.75% cap rate in the listing remarks.

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Winnsboro, SC Commercial real estate Market Trends and Statistics

Explore Commercial real estate leasing options in Winnsboro, SC with 2 listings featured on our commercial real estate exchange. The current inventory includes 2,393 square feet of properties.
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