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    South Carolina Commercial Real Estate for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    Showing 24 of 3,221 results
    Georgetown Retail Space For Lease
    $2,000/Mo
    2,400 SF

    Georgetown Retail Space For Lease

    2400 sq ft retail space in Georgetown, SC for lease.

    7113 South Island Rd., Georgetown, SC 29440
    View details
    Dorchester Pavilion
    $30 SF/Yr
    20,000 SF

    Dorchester Pavilion

    Charleston, SC Restaurant/Medical/Retail Space

    8636 Dorchester Rd, North Charleston, SC 29420
    View details
    Flex/Industrial Space in Northeast Columbia
    $7 SF/Yr
    13,712 SF

    Flex/Industrial Space in Northeast Columbia

    Flex/industrial space with easy access to I-20 and I-77.

    170 Pontiac Business Center Dr., Elgin, SC 29045
    View details
    High-Traffic Retail/Office Space Available
    $16 SF/Yr
    10,361 SF

    High-Traffic Retail/Office Space Available

    Highly visible commercial space on a primary Myrtle Beach corridor.

    2903 North Kings Highway, Myrtle Beach, SC 29577
    View details
    Downtown Conway Professional Office Space
    $18 SF/Yr
    7,000 SF

    Downtown Conway Professional Office Space

    Professional office space in Downtown Conway, available in 2025.

    1312 2nd Avenue, Conway, SC 29577
    View details
    Georgetown Historic District Retail Space
    $3,800/Mo
    1,200 SF

    Georgetown Historic District Retail Space

    Move-in ready retail space in Georgetown's Historic District.

    718 Front St, Georgetown, SC 29440
    View details
    Charleston Historic District Office Space
    $22 SF/Yr
    4,204 SF

    Charleston Historic District Office Space

    Renovated office suites with harbor views in historic Charleston.

    2 Cumberland St, Charleston, SC 29401
    View details
    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF

    Premier Medical Office Space Available

    Class A medical office space in Spartanburg's prime location.

    1650 Skylyn Drive, Spartanburg, SC 29307
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    Freestanding Retail Building For Lease
    $14 SF/Yr
    5,000 SF

    Freestanding Retail Building For Lease

    Freestanding retail building in high-traffic area near Dutch Square Mall.

    422 Bush River Road, Columbia, SC 29210
    View details
    Georgetown Flex Office/Warehouse Space
    $0.73 SF/Yr
    6,000 SF

    Georgetown Flex Office/Warehouse Space

    6000 sqft flex office/warehouse space in downtown Georgetown.

    1434 Hawkins Street, Georgetown, SC 29440
    View details
    Mount Pleasant Retail Space Available
    $24 SF/Yr
    5,250 SF

    Mount Pleasant Retail Space Available

    Retail space in prime Mount Pleasant location, available June 1, 2026.

    543 Long Point Road, Mount Pleasant, SC 29464
    View details
    Trade Shops/Warehouse Space Available
    $800/Mo
    1,250 SF

    Trade Shops/Warehouse Space Available

    Move-in ready units ideal for automotive, trade, and manufacturing.

    2352 Highway 9 East, Longs, SC 29568
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    Ashley Riverview Center Office Space
    $27 SF/Yr
    10,092 SF

    Ashley Riverview Center Office Space

    Multi-tenant office building with Ashley River views and easy access.

    4401 Belle Oaks Dr, North Charleston, SC 29405
    View details
    Prime Retail/Office Space Available
    $12 SF/Yr
    11,970 SF

    Prime Retail/Office Space Available

    Two-story retail/office space in high-traffic Myrtle Beach location.

    6613 N Kings Hwy, Myrtle Beach, SC 29572
    View details
    Retail Space in Commercial Corridor
    $38 SF/Yr
    6,200 SF

    Retail Space in Commercial Corridor

    Highly visible retail space with flexible sizes in Manning, SC.

    2660 Paxville Hwy, Manning, SC 29102
    View details
    Office/Warehouse Space in North Industrial
    $5,833/Mo
    5,000 SF

    Office/Warehouse Space in North Industrial

    5,000 SF office/warehouse space for lease in Myrtle Beach.

    1460 Dividend Loop Unit C, Myrtle Beach, SC 29577
    View details
    Freestanding Building with Drive-Thru
    $35 SF/Yr
    3,400 SF

    Freestanding Building with Drive-Thru

    Freestanding building with drive-thru, convenient access, and high visibility.

    700 N Main St, Summerville, SC 29483
    View details
    Restaurant Space in Drayton Mills
    $29 SF/Yr
    6,979 SF

    Restaurant Space in Drayton Mills

    Second-generation restaurant space in a historic mixed-use development.

    1802 Drayton Road Suite I, Spartanburg, SC 29307
    View details
    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF

    Reimagined Class-A Office Space

    Newly renovated office space in prime downtown location.

    1710 Gervais St., Columbia, SC 29201
    View details
    Office and Flex Warehouse Space
    $1,950/Mo
    2,400 SF

    Office and Flex Warehouse Space

    Office and flex warehouse spaces available for lease.

    354 Tiller Dr, Pawleys Island, SC 29585
    View details
    Myrtle Beach Retail/Office Unit
    $13 SF/Yr
    5,000 SF

    Myrtle Beach Retail/Office Unit

    Retail/office unit in Myrtle Beach's Arts & Innovation District.

    515 9th Avenue North, Myrtle Beach, SC 29577
    View details
    Turnkey Restaurant Space in Iva
    $2,150/Mo
    2,700 SF

    Turnkey Restaurant Space in Iva

    Move-in ready restaurant space with high visibility and convenient access.

    624 East Front Street, Iva, SC 29655
    View details
    Turn-Key Medical Office Space
    $22 SF/Yr
    8,300 SF

    Turn-Key Medical Office Space

    8,300 SF medical office in Surfside Beach, South Carolina.

    1945 Glenns Bay Road, Surfside Beach, SC 29575
    View details
    New Bluffton Flex and Retail
    $25 SF/Yr
    8,000 SF

    New Bluffton Flex and Retail

    New flex and retail buildings in the heart of Bluffton.

    5 Kitties Landing, Bluffton, SC 29910
    View details
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