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    Depew, NY Medical Office Space for Lease

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    East Amherst, NY Buffalo, NY Bowmansville, NY Elma, NY Clarence, NY Queens, NY Orchard Park, NY Alden, NY
    7 properties
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    Medical Office Space Available
    Updated: May 14
    Medical Office Space Available

    4893 Transit Road, Lancaster, NY 14043

    $25 SF/Yr
    3,004 sqft
    Excellent location on heavily travelled Transit Road (Rt. 78) with high visibility (33,000+ vehicles/day) in a rapidly growing trade area.
    Located in a 20,362 SF medical building with established medical co‑tenants (primary medical group, radiology provider).
    3,004 SF former dental suite** suitable for medical/professional conversion.
    Strong area demographics in one of WNY's rapidly growing communities.
    Ample on‑site parking.
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    Versatile Space in Catalyst Fitness Plaza
    Updated: Mar 5
    Versatile Space in Catalyst Fitness Plaza

    5087 Broadway, Depew, NY 14043

    $12 SF/Yr
    23,000 sqft
    High‑traffic corner location on Broadway & Penora Street with access from both streets.
    Diverse tenant mix including national retailers like Tops, Big Lots, and Dollar Tree.
    Ample parking with over 240 spaces.
    Available 23,000 +/- SF warehouse space with 2 docks and 2 drive‑in doors, divisible from 7,000 +/- SF.**
    Existing 5,500 +/- SF medical office space with 23 +/- private rooms and 4 restrooms, convertible to retail.**
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    Medical Building with Development Potential
    Medical Building with Development Potential

    3083 William Street, Cheektowaga, NY 14227

    Contact for pricing
    3,200 sqft

    Partially leased medical building with developable lot on William Street.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Medical Office Space Available
    Medical Office Space Available

    Cheektowaga, NY

    Contact for pricing
    11,331 sqft 2.47 AC lot

    Medical office space available for lease in 2025.

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    Transit Road Retail/Office Space
    Transit Road Retail/Office Space

    4711 Transit Rd, Lancaster, NY

    Contact for pricing
    3,168 sqft 1.12 AC lot

    Mixed-use center with high visibility and ample parking.

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    Office Units Near Transit
    Office Units Near Transit

    928 French Rd, Cheektowaga, NY 14227

    Contact for pricing
    1,250 sqft

    Office accommodation suited to medical or professional use, with parking and transit access nearby.

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    Medical Office Space with On-Site Parking
    Medical Office Space with On-Site Parking

    345 Dick Rd, Depew, NY 14043

    Contact for pricing
    2,000 sqft

    C-2 zoned medical office with on-site parking and a chiropractor willing to sign a five-year lease.

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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 7 Active listings in Depew, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Medical Office Space for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    West Seneca Medical/Office Space
    West Seneca Medical/Office Space

    220 Center Road, West Seneca, NY 14224

    $4,000/Mo
    4,500 sqft

    4,500+/- SF medical/office space in high-traffic West Seneca location.

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    Medical Office Building with Adjacent Lot
    Medical Office Building with Adjacent Lot

    3083 William St, Buffalo, NY 14227

    Contact for pricing
    7,404 sqft

    Medical-focused building with an adjacent parcel and second-floor office space.

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    West Seneca Medical Office Suites
    West Seneca Medical Office Suites

    550 Orchard Park Road, West Seneca, NY 14224

    Contact for pricing
    6,495 sqft

    Medical office suites available for lease in West Seneca.

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    First Floor Office Space Available
    First Floor Office Space Available

    4245 Union Rd, Buffalo, NY 14225

    Contact for pricing
    1,768 sqft

    Office space for rent in excellent location with high visibility.

    View details

    Similar Spaces for Sale in Depew, NY

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Medical Office Building with Adjacent Lot
    Medical Office Building with Adjacent Lot

    3083 William Street, Cheektowaga, NY 14227

    $650,000
    7,404 sqft

    Partially leased healthcare property includes additional land for expansion or parking.

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    Medical Office/Retail Building
    Medical Office/Retail Building

    6140 Transit Rd, Depew, NY 14043

    Contact for pricing
    5,520 sqft

    Medical office/retail building in C-2 Shopping Center District on a high-traffic corridor near a new O’Reilly Auto Parts.

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    Medical/Professional Office Plaza
    Medical/Professional Office Plaza

    6199 Transit Rd, Depew, NY 14043

    Contact for pricing
    16,763 sqft 1.00 AC lot

    Retail and office plaza offering 161 feet of frontage along Transit Road with prominent parking and pylon signage.

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    Two-Story Medical Office Building
    Two-Story Medical Office Building

    345 Dick Rd, Depew, NY 14043

    Contact for pricing
    6,400 sqft

    Two-story office building with 25 parking spaces, C-2 zoning, and a roof replaced in 2009.

    View details

    Depew, NY Medical Office Space Lease Rates & Market Statistics

    Browse 7 Medical Office Space listings for lease in Depew, NY on Realmo, a commercial real estate marketplace serving the Depew area. The current inventory totals 46,953 square feet of properties.

    Asking lease rates for Medical Office Space in Depew start at $12 SF/Yr, average $18.50 SF/Yr, and reach $25 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $18.50 SF/Yr is 44% below the New York state average of $32.74 SF/Yr.

    Depew accounts for 11% of the 65 medical office space listings currently available across Erie County, where nearby markets include Buffalo and West Seneca. Medical Office Space listings make up 19% of the 36 Office Spaces currently for lease in Depew, with asking rates averaging $18.50 SF/Yr — 13% above the citywide Office Spaces average of $16.41 SF/Yr. Tenants comparing options may also consider Office Units (26 listings) and Office buildings (7 listings) elsewhere in the Depew market.

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    • 14227

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