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Buffalo, NY Medical Centers for Sale

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Main Street Portfolio in Buffalo
$8,000,000

Main Street Portfolio in Buffalo

1160 Main St, Buffalo, NY 14209

Two interconnected buildings with redevelopment potential in Buffalo's Midtown corridor.

  • Prime location in Buffalo's thriving Main Street corridor
  • Substantial square footage (113,684 SF) and flexible floorplans
  • High‑visibility frontage on heavily traveled Main Street with excellent accessibility
  • Significant income potential exceeding $1.1 million annually
  • Zoned N‑1C for flexible mixed‑use or redevelopment
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Based on your search, we've compiled 55 Potential Opportunities for your consideration. Besides 1 Active listings in Buffalo, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 50 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Leased Medical Office/Surgi-Center For Sale
Contact for pricing

Leased Medical Office/Surgi-Center For Sale

100% leased medical office building with surgi-center and strong NOI.

Monongahela, PA 15063
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Monongahela Medical Office Building For Sale
$8,500,000
40,366 SF

Monongahela Medical Office Building For Sale

Fully leased medical office building with surgi-center and strong NOI.

100 Stoops Dr, Monongahela, PA 15063
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Saginaw Medical Building For Sale
$1,509,790

Saginaw Medical Building For Sale

Single tenant Fresenius Medical Care building in Saginaw, Michigan.

920 North Niagara St, Saginaw, MI 48602
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Saginaw Office Building For Sale
$2,900,000
31,725 SF

Saginaw Office Building For Sale

Class A Office Building, 31,725 SF

4300 Fashion Square Blvd, Saginaw, MI 48603
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Explore Off-Market Properties in Buffalo, NY

Consider similar Off-Market properties in Buffalo, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

666 Oak St

666 Oak St

MEDICAL CLINIC • 24,702 SF
Value Estimation
$745,000
666 Oak St, Buffalo, NY 14203
View details
2228 Old Un Rd

2228 Old Un Rd

MEDICAL CLINIC • 31,608 SF
Value Estimation
$1,005,000
2228 Old Un Rd, Buffalo, NY 14227-2728
View details
124 Maryland St

124 Maryland St

MEDICAL CLINIC • 9,084 SF
Value Estimation by Request
124 Maryland St, Buffalo, NY 14201
View details
101 Oak St

101 Oak St

MEDICAL CLINIC • 67,325 SF
Value Estimation
$1,040,000
101 Oak St, Buffalo, NY 14203-2233
View details
1091 Abbott Rd

1091 Abbott Rd

MEDICAL CLINIC • 4,937 SF
Value Estimation by Request
1091 Abbott Rd, Buffalo, NY 14220
View details
200 Albany St

200 Albany St

MEDICAL CLINIC • 7,004 SF
Value Estimation by Request
200 Albany St, Buffalo, NY 14213-1801
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700 Ellicott St

700 Ellicott St

MEDICAL CLINIC • 75,255 SF
Value Estimation
$1,860,000
700 Ellicott St, Buffalo, NY 14203-1102
View details
920 Harlem Rd

920 Harlem Rd

MEDICAL CLINIC • 8,887 SF
Value Estimation by Request
920 Harlem Rd, Buffalo, NY 14224-1008
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2963 Main St

2963 Main St

MEDICAL CLINIC • 17,888 SF
Value Estimation by Request
2963 Main St, Buffalo, NY 14214-1003
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1176 Main St

1176 Main St

MEDICAL CLINIC • 22,228 SF
Value Estimation by Request
1176 Main St, Buffalo, NY 14209-2102
View details
225 Como Park Blvd

225 Como Park Blvd

MEDICAL CLINIC • 48,100 SF
Value Estimation
$1,370,000
225 Como Park Blvd, Buffalo, NY 14227-1416
View details
45 Carlton St

45 Carlton St

MEDICAL CLINIC • 12,084 SF
Value Estimation by Request
45 Carlton St, Buffalo, NY 14203
View details
2495 Elmwood Ave

2495 Elmwood Ave

MEDICAL CLINIC • 6,400 SF
Value Estimation by Request
2495 Elmwood Ave, Buffalo, NY 14217-2222
View details
120 Gardenville W Pkwy

120 Gardenville W Pkwy

MEDICAL CLINIC • 35,405 SF
Value Estimation
$555,000
120 Gardenville W Pkwy, Buffalo, NY 14224-1324
View details
2497 Delaware Ave

2497 Delaware Ave

MEDICAL CLINIC • 7,583 SF
Value Estimation by Request
2497 Delaware Ave, Buffalo, NY 14216-1712
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1175 Delaware Ave

1175 Delaware Ave

MEDICAL CLINIC • 54,540 SF
Value Estimation
$785,000
1175 Delaware Ave, Buffalo, NY 14209-1401
View details
374 7th St

374 7th St

MEDICAL CLINIC • 5,476 SF
Value Estimation by Request
374 7th St, Buffalo, NY 14201
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1294 Niagara St

1294 Niagara St

MEDICAL CLINIC • 47,883 SF
Value Estimation
$695,000
1294 Niagara St, Buffalo, NY 14213
View details
197 Summer St

197 Summer St

MEDICAL CLINIC • 8,694 SF
Value Estimation by Request
197 Summer St, Buffalo, NY 14222-2397
View details
78 Northland Ave

78 Northland Ave

MEDICAL CLINIC • 4,335 SF
Value Estimation by Request
78 Northland Ave, Buffalo, NY 14208-1103
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187 Bryant St

187 Bryant St

MEDICAL CLINIC • 4,410 SF
Value Estimation by Request
187 Bryant St, Buffalo, NY 14222-2065
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50 En St

50 En St

MEDICAL CLINIC • 32,760 SF
Value Estimation
$820,000
50 En St, Buffalo, NY 14203-1002
View details
1597 Elmwood Ave

1597 Elmwood Ave

MEDICAL CLINIC • 3,570 SF
Value Estimation
$2,615,000
1597 Elmwood Ave, Buffalo, NY 14207-3017
View details

Buffalo, NY Medical Centers Investment Opportunities Market Analysis

Explore 51 medical centers for sale in Buffalo, NY on our real estate platform. These investment opportunities span a total of 764,699 square feet of properties for sale, with an estimated market value of $11,385,000.

Sale prices for medical buildings in Buffalo, NY start at $70,000, averaging $421,666, and reaching up to $2,450,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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