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    Buffalo, NY Healthcare Properties for Sale

    14 results
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    Turnkey Medspa Business Opportunity
    $150,000

    Turnkey Medspa Business Opportunity

    3969 Main St, Buffalo, NY 14226

    Established medspa business for sale with equipment and client list.

    • Established, Turnkey Medspa Business with Existing Client List
    • Includes All Equipment Necessary for Operations
    • Prime Location with Supporting Demographics
    • Owner Willing to Assist with Transition
    • State‑of‑the‑Art Aesthetic and Laser Treatment Equipment
    Updated: Dec 19, 2025
    View details
    Premium Medical Office Building For Sale
    $1,399,000

    Premium Medical Office Building For Sale

    8270 Wehrle Dr, Buffalo, NY 14221

    Medical office building in Williamsville, NY, with modern, flexible layout.

    • Prime Location: Highly desirable Williamsville location with excellent visibility and easy access to major thoroughfares.
    • Quality Facility: Modern, flexible layout with high‑end finishes suitable for various medical uses.
    • Medical‑Grade Infrastructure: Equipped with advanced HVAC systems and ADA‑compliant entrances.
    • Ample Parking: 58 on‑site parking spots for patients and staff.
    • Prestigious Building: Well‑maintained, professionally managed building ensuring high standards.
    Updated: Mar 25, 2025
    View details
    I-90 Regional Development Site
    Contact for pricing
    93,100 SF

    I-90 Regional Development Site

    Prime West Seneca medical office & development land

    355 Orchard Park Rd, West Seneca, NY 14224
    View details
    Williamsville Medical Office Condo
    $495,000
    3,708 SF

    Williamsville Medical Office Condo

    Prime Main St location, 3708 SF, $495,000

    6480 Main St, Williamsville, NY 14221
    View details
    Main Street Williamsville Office Building
    $1,500,000
    10,500 SF

    Main Street Williamsville Office Building

    10,500 SF Office, 60 Parking Spaces, $1.5M

    6645 Main St, Williamsville, NY 14221
    View details
    Prime Buffalo Medical Office Building
    $1,700,000
    19,000 SF

    Prime Buffalo Medical Office Building

    19,000 SF Class A Medical Office, $1.7M

    235 North St, Buffalo, NY 14201
    View details
    Executive Office Building, Buffalo
    $1,800,000
    12,000 SF

    Executive Office Building, Buffalo

    12,000 SF Office, Prime Location

    2060 Sheridan Dr, Buffalo, NY 14223
    View details
    Main Street Office Building
    $2,300,000
    33,000 SF

    Main Street Office Building

    33,000 SF Office Building, Buffalo, NY

    1236 Main St, Buffalo, NY 14209
    View details
    Delaware Ave Office Building
    $3,500,000
    42,130 SF

    Delaware Ave Office Building

    42,130 SF Office Building, Buffalo, NY

    560 Delaware Ave, Buffalo, NY 14202
    View details
    Woodlawn School: Redevelopment Gem
    $899,999
    33,000 SF

    Woodlawn School: Redevelopment Gem

    33,000 SF Mixed-Use Opportunity

    3656 Milestrip Rd, Buffalo, NY 14219
    View details
    Former Nursing Home Redevelopment Opportunity
    Contact for pricing

    Former Nursing Home Redevelopment Opportunity

    39,496 SF building on 1.43 acres for redevelopment.

    3600 Harlem Rd, Buffalo, NY 14215
    View details
    Office/Retail/Medical Building with Warehouse
    $1,500,000
    12,400 SF

    Office/Retail/Medical Building with Warehouse

    Office/Retail/Medical building with detached warehouse for sale or lease.

    1770 Northwood Dr, Buffalo, NY 14223
    View details
    Main Street Portfolio in Buffalo
    $8,000,000

    Main Street Portfolio in Buffalo

    Two interconnected buildings with redevelopment potential in Buffalo's Midtown corridor.

    1160 Main St, Buffalo, NY 14209
    View details
    End-Cap Retail/Office/Medical Space
    $259,000

    End-Cap Retail/Office/Medical Space

    2,850+/- SF end-cap in Kenmore's Elmwood Business district.

    2454 Elmwood Ave, Kenmore, NY 14217
    View details
    Based on your search, we've compiled 143 Potential Opportunities for your consideration. Besides 14 Active listings in Buffalo, NY, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 125 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Orchard Park Office/Retail Building
    $479,900
    3,284 SF

    Orchard Park Office/Retail Building

    3284 SF building on 1.2 acres in Orchard Park.

    3095 Southwestern Blvd, Orchard Park, NY 14127
    View details
    Single-Story Building on 1.72 Acres
    $1,295,000
    12,300 SF

    Single-Story Building on 1.72 Acres

    12,300 sq ft building suitable for various commercial uses.

    3385 Orchard Park Rd, Orchard Park, NY 14127
    View details
    Lockport Office Building, NY
    Contact for pricing
    3,600 SF

    Lockport Office Building, NY

    3600+ SF, 2 Suites Available

    16 Davison Ct, Lockport, NY 14094
    View details
    Lockport Office Building For Sale
    Contact for pricing
    3,407 SF

    Lockport Office Building For Sale

    Vacant Executive/Medical Office, 3407 SF

    140 Professional Pkwy, Lockport, NY 14094
    View details

    Explore Off-Market Properties in Buffalo, NY

    Consider similar Off-Market properties in Buffalo, NY. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    478 Main Rd

    478 Main Rd

    Lifestyle centers • 151,605 SF
    Value Estimation by Request
    478 Main Rd, Buffalo, NY 14202
    View details
    3720 Park Ave

    3720 Park Ave

    Medical offices • 9,728 SF
    Value Estimation by Request
    3720 Park Ave, Buffalo, NY 14219
    View details
    776 Tonawanda St

    776 Tonawanda St

    Medical space • 7,200 SF
    Value Estimation by Request
    776 Tonawanda St, Buffalo, NY 14207
    View details
    3236 Transit Rd

    3236 Transit Rd

    Medical offices • 16,000 SF
    Value Estimation by Request
    3236 Transit Rd, West Seneca, NY 14224
    View details
    1307 Jefferson Ave

    1307 Jefferson Ave

    Medical offices • 28,290 SF
    Value Estimation by Request
    1307 Jefferson Ave, Buffalo, NY 14208
    View details
    936 Delaware Ave

    936 Delaware Ave

    Medical offices • 38,450 SF
    Value Estimation by Request
    936 Delaware Ave, Buffalo, NY 14209
    View details
    950 Union Rd

    950 Union Rd

    Medical space • 390,910 SF
    Value Estimation by Request
    950 Union Rd, West Seneca, NY 14224
    View details
    1010 Main Rd

    1010 Main Rd

    Medical offices • 36,399 SF
    Value Estimation by Request
    1010 Main Rd, Buffalo, NY 14202
    View details
    39 Maple Rd

    39 Maple Rd

    Medical offices • 823 SF
    Value Estimation by Request
    39 Maple Rd, Buffalo, NY 14221
    View details
    6480 Main St

    6480 Main St

    Medical offices • 3,708 SF
    Value Estimation by Request
    6480 Main St, Williamsville, NY 14221
    View details

    Buffalo, NY Healthcare Properties Investment Opportunities Market Analysis

    Explore 139 healthcare properties for sale in Buffalo, NY, showcased through 14 active listings on our real estate platform. These investment opportunities span a total of 4,078,684 square feet of properties for sale, with an estimated market value of $39,004,999.

    Sale prices for medical real estate in Buffalo, NY start at $70,000, averaging $886,477, and reaching up to $8,340,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Healthcare properties for Sale Near Buffalo, NY

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    Most Searched ZIP Codes in Buffalo, NY

    • 14221
    • 14209
    • 14223
    • 14201
    • 14202
    • 14215
    • 14217
    • 14219
    • 14224
    • 14226

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