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    South Carolina Commercial Real Estate for Lease

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    3,013 properties
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    ESFR Distribution Center
    ESFR Distribution Center

    2494 Florence Harllee Boulevard, Florence, SC 29506

    $6.50 SF/Yr
    100,256 sqft  28 ft clear  15 docks + 1 drive-in  50 x 50 ft

    Industrial facility offers dock access, drive-in loading, and warehouse-scale logistics functionality.

    Sprinklered  188 parking spaces
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    Dual-Entry Retail Suite
    Dual-Entry Retail Suite

    12270 Highway 17 Bypass #Unit A, Murrells Inlet, SC 29576

    $1,950/Mo
    1,250 sqft
    36,500 VPD

    The finished suite has customer doors on its front and north-facing sides.

    Pylon signage
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    Flexible Commercial Building
    Flexible Commercial Building

    1524 Ashley River Rd, Charleston, SC 29407

    Heathwood/Old Towne
    $4,500/Mo
    Highway access  Road access

    Commercial building with adaptable space and road frontage near downtown Charleston and I-526.

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    Flexible Workspace Solutions at SC, Sumter - West Hampton Avenue. Contact us today to book a tour!
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    Former School Property
    Former School Property

    1403 Highway 90, Conway, SC 29526

    Contact for pricing
    15,000 sqft  6 acres

    CFA zoning and two buildings offer varied space for commercial and institutional use.

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    Suburban Office Park in Greenville
    Suburban Office Park in Greenville

    124 Verdae Blvd, Greenville, SC 29607

    $22.50 SF/Yr
    657–1,095 people  1 space  164,299 sqft

    Office park in prime business district near shopping and restaurants.

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    Automotive Property with Paved Yard
    Automotive Property with Paved Yard

    1401 Hwy 9 Bypass, Lancaster, SC 29720

    $4,500/Mo
    1,279 sqft  Built 1997

    Office configuration includes multiple rooms, storage areas, and two restrooms.

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    End-Cap Retail Suite
    End-Cap Retail Suite

    154 Robert Smalls Parkway, Beaufort, SC 29906

    Triple net (NNN)
    $29 SF/Yr
    4,258 sqft  Built 2002
    Highway access

    A rear service area and bay door support a range of commercial operations.

    36 parking spaces  Excellent co-tenancy  Prominent monument signage  Rear loading area
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    Downtown Mixed-Use Space with Parking
    Downtown Mixed-Use Space with Parking

    1203 Main St., Conway, SC 29526

    $3,338/Mo
    1,535 sqft
    Road access  DT

    The downtown space offers professional interiors and a dedicated private parking lot.

    Private parking lot  Prominent Main Street frontage  Excellent visibility  Pedestrian traffic
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    Retail Space with Central Air
    Retail Space with Central Air

    1182 stonecrest Boulevard, Tega Cay, SC 29708

    $3,000/Mo
    Multi-tenant  1,200 sqft  Built 2021
    Tega cay family Dentistry, Simpson law firm co-tenants

    Commercial space in a PUD with a bathroom and public sewer service.

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    Freestanding Building in West Columbia
    Freestanding Building in West Columbia

    1210 Charleston Hwy., West Columbia, SC 29169

    $18.50 SF/Yr
    10,000 sqft

    10,125 SF freestanding building on a busy retail corridor.

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    Industrial Space in North Park
    Industrial Space in North Park

    1471 Dividend Loop, Myrtle Beach, SC 29577

    $16 SF/Yr
    15,000 sqft  Built 2026

    15,000 SF industrial space with build-to-suit office options.

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    Commercial Office Space with Parking
    Commercial Office Space with Parking

    105-2514 River Rd, Piedmont, SC 29673

    Triple net (NNN)
    $1,445/Mo
    4–8 people  1,200 sqft
    Highway access + Road access

    Flexible office space with modern finishes and on-site parking, available now with water and trash included.

    On-site parking
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    Greenville Office Space for Lease
    Greenville Office Space for Lease

    2000 Wade Hampton Boulevard, Greenville, SC 29615

    $19 SF/Yr
    755–1,259 people  188,900 sqft

    Up to 188,900 SF available, near Downtown Greenville.

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    Warehouse Under Construction in Conway
    Warehouse Under Construction in Conway

    155 East Cox Ferry Road, Conway, SC 29526

    $14 SF/Yr
    10,065 sqft

    Warehouse with office space, dock, and roll-up doors, available Q3 2026.

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    Service Garage with Storage Loft
    Service Garage with Storage Loft

    710 Seneca Drive, Seneca, SC 29678

    $2,000/Mo
    3,264 sqft

    A service garage includes office, parts room, loft storage, and roll-up doors.

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    New Bluffton Flex and Retail
    New Bluffton Flex and Retail

    5 Kitties Landing, Bluffton, SC 29910

    $25 SF/Yr
    8,000 sqft

    New flex and retail buildings in the heart of Bluffton.

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    Salon Suite with Sink
    Salon Suite with Sink

    2206 Mossy Oaks Road, Port Royal, SC 29935

    Full service
    $625/Mo
    80 sqft  Built 1999

    Compact salon space with a private sink, shared lobby, and two common bathrooms.

    Utilities to site  Lobby area  Shared bathrooms  Sink
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    Business-Ready Workspace at SC, Aiken – Trail Ridge. Contact us today to book a tour!
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    Retail Space with Drive-Up Windows
    Retail Space with Drive-Up Windows

    5 S Church Street, Manning, SC 29102

    $1,280/Mo
    Multi-tenant  1,500 sqft

    A lobby and rear work area provide a practical layout for customer service and back-of-house tasks.

    Drive-thru
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    Class A Office Downtown Charleston
    Class A Office Downtown Charleston

    525 East Bay Street, Charleston, SC 29403

    Garden District
    $39 SF/Yr
    58–96 people  14,515 sqft

    Class A office space for rent in downtown Charleston.

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    Serviced Office Space for Rent at SC, Hilton Head - Office Park Road. Contact us today to book a tour!
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    Serviced Offices with Business Support at SC, North Charleston - Aviation Center. Contact us today to book a tour!
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    New Bluffton Flex/Retail Buildings
    New Bluffton Flex/Retail Buildings

    5 Kitties Landing, Bluffton, SC 29910

    $25 SF/Yr
    11,360 sqft

    Two new buildings for sale in Bluffton, South Carolina.

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