Office Building

Buffalo, NY Office Buildings for Lease

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50 properties
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Two-Story Office Building
Updated: Jun 25
Two-Story Office Building

3686 Seneca Street, Buffalo, NY 14224

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2,603 sqft 0.53 AC lot
2,603‑square‑foot two‑story office building
0.526‑acre parcel with 10 on‑site parking spaces
Five private offices plus reception, waiting, and conference areas
Kitchenette, two bathrooms, and basement space
Natural gas forced‑air heating and central air conditioning
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Corner Office Building for Lease
Updated: Mar 5
Corner Office Building for Lease

2060 Sheridan Drive, Buffalo, NY 14223

$16 SF/Yr
12,000 sqft
12,000 SF office building ideal for owner occupancy or up to 3 tenants.
Excellent location** at the corner of Sheridan Dr. and Colvin Blvd, with easy access to amenities and major routes (I‑290).
34 parking spaces with two curb cuts for easy accessibility.
ADA accessibility with wheelchair ramp and designated parking.
Equipped with elevator access** to all 3 floors, north and south stairwells, and a security system.
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Renovated Office Building in Williamsville
Renovated Office Building in Williamsville

395 Youngs Road, Williamsville, NY 14221

$20 SF/Yr
29,729 sqft 6.20 AC lot

Freestanding, single-story Class A office building available for lease/purchase.

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Historic Mixed-Use Building in Buffalo
Historic Mixed-Use Building in Buffalo

111 Genesee Street |, Buffalo, NY 14203

$18 SF/Yr
81,261 sqft

Restored mixed-use property with retail, office, and apartments.

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Historic Brick Office Building
Historic Brick Office Building

1334 Broadway Street, Buffalo, NY 14212

$2,000/Mo

1909 historic brick office building with a newer roof and updates, offered as-is for sale or lease.

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Recently Renovated Office Building
Recently Renovated Office Building

471 Delaware Ave, Buffalo, NY 14202

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3,600 sqft

Recently renovated office building with seven off-street parking spots in Buffalo’s downtown business district.

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Multi-Office Building with Separate Entrances
Multi-Office Building with Separate Entrances

875 Hopkins Rd, Buffalo, NY 14221

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3,600 sqft

Two-story office building offers private offices, conference rooms, open space, and kitchen across separate floor plans.

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Office Building with Attached Parking Garage
Office Building with Attached Parking Garage

257 W Genesee St, Buffalo, NY 14201

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4,594 sqft

Office building with secured key card access and an attached parking garage with highway access nearby.

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Standalone Office Building
Standalone Office Building

90 Sylvan Pkwy, Buffalo, NY 14228

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3,000 sqft

Standalone office building with updated interior finishes and ample on-site parking in a park-like setting.

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Handsomely Appointed Office Suites
Handsomely Appointed Office Suites

403 Main St, Buffalo, NY 14203

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600 sqft

Multiple office suites are available in a handicapped-accessible building with an elegant lobby and street parking nearby.

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Office Building with Secured Parking
Office Building with Secured Parking

257 W Genesee St, Buffalo, NY 14201

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5,210 sqft

Office building with an attached secured parking garage and key-card access throughout the building and garage.

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Office Building with Secured Parking Garage
Office Building with Secured Parking Garage

257 W Genesee St, Buffalo, NY 14201

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4,094 sqft

Office building with key card access and an attached 1,500-space secured parking garage.

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Office Suite Building
Office Suite Building

403 Main St, Buffalo, NY 14203

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450 sqft

Handsomely appointed office suites are available with a fully appointed conference room and handicapped accessibility.

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Secured Parking Office Building
Secured Parking Office Building

257 W Genesee St, Buffalo, NY 14201

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4,337 sqft

Office building with an attached 1,500-space secured parking garage and key-card security access throughout.

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Class A Office Building
Class A Office Building

665 Main Street, Buffalo, NY 14203

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60,000 sqft

Downtown office property with prominent corridor exposure, pedestrian activity, and on-site parking.

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Downtown Buffalo Office Space
Downtown Buffalo Office Space

300 Pearl Street, Buffalo, NY 14202

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29,454 sqft

Office complex in downtown Buffalo, proximate to courts and offices.

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LEED Silver Office Building
LEED Silver Office Building

257 West Genesee Street, Buffalo, NY 14202

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233,121 sqft

Office spaces for lease with lake and downtown views.

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Remodeled Office Building For Rent
Remodeled Office Building For Rent

1271 Harlem Road, Buffalo, NY 14206

$3,000/Mo

Stand-alone office building with recent remodeling and included utilities.

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Modern Office Building for Lease
Modern Office Building for Lease

40 Gardenville Pkwy W, West Seneca, NY 14224

$15 SF/Yr
3.30 AC lot

Renovated office spaces with flexible lease options and ample parking.

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Class A Trophy Office Space
Class A Trophy Office Space

6467 Main St, Williamsville, NY 14221

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27,150 sqft

Class A office space available for rent.

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Four-Story Medical Office Building
Four-Story Medical Office Building

11 Summer St, Buffalo, NY 14209

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16,000 sqft

Turnkey ground floor includes reception, kitchenette, and perimeter exam or office rooms in a four-story building.

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Medical/Professional Office Building For Rent
Medical/Professional Office Building For Rent

52 S Union Rd, Buffalo, NY 14221

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20,000 sqft

Two-story, 20,000 SF medical/professional office building in Williamsville.

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Classical Revival Office Space
Classical Revival Office Space

374 Delaware Ave, Buffalo, NY 14202

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3,346 sqft

Class A office space with a large open layout, new carpet, and large windows within the 1922 Huyler Building.

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Two-Story Office Building
Two-Story Office Building

3686 Seneca Street, West Seneca, NY 14224

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Configured with private offices, reception, conference, waiting, kitchenette, and on-site parking.

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Buffalo, NY Office buildings Lease Rates & Market Statistics

Explore 50 Office buildings for lease in Buffalo, NY on Realmo, a commercial real estate exchange covering the Buffalo area. The current inventory totals 736,163 square feet of properties — an average of ~14,700 SF per listing.

Asking lease rates for Office buildings in Buffalo start at $15 SF/Yr, average $17.25 SF/Yr, and reach $20 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. The local average of $17.25 SF/Yr is 57% below the New York state average of $39.90 SF/Yr.

Buffalo accounts for 69% of the 72 office buildings currently available across Erie County, where nearby markets include Getzville and Hamburg. Office buildings make up 21% of the 240 Office Spaces currently for lease in Buffalo, with asking rates averaging $17.25 SF/Yr — 24% above the citywide Office Spaces average of $13.87 SF/Yr. Tenants comparing options may also consider Office Units (170 listings) and Medical Office Space (35 listings) elsewhere in the Buffalo market.

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