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    Buffalo, NY Office Buildings for Lease

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    New York, NY Brooklyn, NY Queens, NY
    30 results
    Two-Story Office Building in Buffalo
    $249,900 SF/Yr
    2,603 SF

    Two-Story Office Building in Buffalo

    3686 Seneca Street, Buffalo, NY 14224

    Two-story office building for sale or lease in West Seneca.

    • Prime location in the heart of West Seneca, with easy access to I‑90, US 219, and Union Road.
    • Functional layout featuring five private offices, a conference room, reception area, kitchenette, and two bathrooms.
    • On‑site parking lot with 10 parking spaces.
    • Suitable for various small businesses such as law offices, accounting firms, and insurance companies.
    • Accessibility features including an accessible approach with ramp.
    Updated: Dec 4, 2025
    View details
    Spacious Commercial Building, Buffalo, NY
    $499,900 SF/Yr
    5,012 SF

    Spacious Commercial Building, Buffalo, NY

    1609 Genesee Street, Buffalo, NY 14211

    Versatile commercial building with parking, suitable for various businesses.

    • High‑visibility location on Genesee St with oversized parking lot (25+ spaces).
    • Over 5,000 sq. ft. of versatile commercial space suitable for various business types.
    • Fully accessible with elevator, wheelchair ramp, and wide hallways.
    • Valid Certificate of Occupancy and ready for immediate use.
    • Two‑story brick building with 4 bathrooms, laundry areas on each level, and kitchen area.
    Updated: Dec 1, 2025
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    Furnished Class A Office Space
    $19 SF/Yr
    5,700 SF

    Furnished Class A Office Space

    5,700 SF furnished office space in central business district.

    477 Main Street, Buffalo, NY 14203
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    Renovated Office Building in Buffalo
    $15 SF/Yr
    30,150 SF

    Renovated Office Building in Buffalo

    30,150 SF renovated office building in downtown Buffalo.

    374 Delaware Ave, Buffalo, NY 14202
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    Renovated Office Building in Williamsville
    $20 SF/Yr
    29,729 SF

    Renovated Office Building in Williamsville

    Freestanding, single-story Class A office building available for lease/purchase.

    395 Youngs Road, Williamsville, NY 14221
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    Corner Office Building for Lease
    Contact for pricing
    12,000 SF

    Corner Office Building for Lease

    Two-story office building with multiple tenant options and ample parking.

    2060 Sheridan Drive, Buffalo, NY 14223
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    Historic Downtown Office and Retail
    Contact for pricing
    169,640 SF

    Historic Downtown Office and Retail

    Renovated office and retail spaces in historic 1895 building.

    403 Main Street, Buffalo, NY 14203
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    Freestanding Building on Large Lot
    $16 SF/Yr
    1,800 SF

    Freestanding Building on Large Lot

    1800 SF building on one-acre lot available for lease.

    1963 Fillmore Avenue, Buffalo, NY 14214
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    LEED Silver Office Building
    Contact for pricing
    233,121 SF

    LEED Silver Office Building

    Office spaces for lease with lake and downtown views.

    257 West Genesee Street, Buffalo, NY 14202
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    Downtown Buffalo Office Space
    Contact for pricing
    29,454 SF

    Downtown Buffalo Office Space

    Office complex in downtown Buffalo, proximate to courts and offices.

    300 Pearl Street, Buffalo, NY 14202
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    Downtown Buffalo Office/Retail Building
    $699,999 SF/Yr
    8,700 SF

    Downtown Buffalo Office/Retail Building

    8700 SF office/retail building in downtown Buffalo for lease.

    1160 Main St, Buffalo, NY 14209
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    Remodeled Office Building For Rent
    Contact for pricing

    Remodeled Office Building For Rent

    Stand-alone office building with recent remodeling and included utilities.

    1271 Harlem Road, Buffalo, NY 14206
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    Downtown Building with On-Site Parking
    Contact for pricing
    11,289 SF

    Downtown Building with On-Site Parking

    Corner building with kitchen, bathrooms, and access to expressways.

    703 Washington Street, Buffalo, NY 14203
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    84,000 SF Professional Building
    Contact for pricing
    84,000 SF

    84,000 SF Professional Building

    Three-story building in walkable Williamsville with retail and office space.

    5500 Main St, Williamsville, NY
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    Delaware Avenue Medical Office Space
    Contact for pricing
    5,868 SF

    Delaware Avenue Medical Office Space

    Medical office space near Allentown and Buffalo's medical campus.

    520 Delaware Ave, Buffalo, NY
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    Class A Office Building
    Contact for pricing
    68,000 SF

    Class A Office Building

    Premier office space in downtown Buffalo with high visibility.

    Buffalo, NY 14203
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    Medical/Professional Office Building For Rent
    Contact for pricing
    20,000 SF

    Medical/Professional Office Building For Rent

    Two-story, 20,000 SF medical/professional office building in Williamsville.

    52 S Union Rd, Buffalo, NY 14221
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    Office/Retail/Medical Building with Warehouse
    $12 SF/Yr
    12,400 SF

    Office/Retail/Medical Building with Warehouse

    Freestanding building with warehouse on a signalized corner.

    1770 Colvin Blvd, Buffalo, NY
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    Class A Trophy Office Space
    Contact for pricing
    27,150 SF

    Class A Trophy Office Space

    Class A office space available for rent.

    6467 Main St, Williamsville, NY 14221
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    Class A Office Space Available
    $18 SF/Yr
    10,000 SF

    Class A Office Space Available

    State-of-the-art office building with flexible floor plans for rent.

    20 Lawrence Bell Dr, Buffalo, NY 14221
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    Brick Building with Ample Parking
    Contact for pricing
    4,800 SF

    Brick Building with Ample Parking

    4800 sq ft building suitable for office or retail.

    2282 Elmwood Ave, Buffalo, NY 14217
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    Corner Office Building For Lease
    Contact for pricing
    12,000 SF

    Corner Office Building For Lease

    Two-story office building with multiple tenant options and ample parking.

    2060 Sheridan Dr, Buffalo, NY 14223
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    Downtown Buffalo Office Building
    Contact for pricing
    3,204 SF

    Downtown Buffalo Office Building

    71,200 SF office building with ample on-site parking.

    325 Delaware Ave, Buffalo, NY
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    Main Street Office Building Available
    Contact for pricing
    3,652 SF

    Main Street Office Building Available

    Two-story office building near transportation and downtown.

    1437 Main St, Buffalo, NY 14209
    View details

    Buffalo, NY Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Buffalo, NY with 30 listings featured on our commercial real estate exchange. The current inventory includes 2,083,431,240 square feet of properties with an estimated lease value of $51 SF/Yr.

    Estimated lease rates for Office buildings in Buffalo, NY begin at $12 SF/Yr, with an average of $17 SF/Yr and extend to $20 SF/Yr.
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    Popular Searches in Buffalo, NY

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    Most Searched ZIP Codes in Buffalo, NY

    • 14203
    • 14202
    • 14209
    • 14221
    • 14223
    • 14206
    • 14211
    • 14214
    • 14217
    • 14224
    • 14226

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