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    Buffalo, NY Medical Offices for Lease

    49 results
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    Elmwood Avenue Professional Office Space
    $15 SF/Yr
    7,344 SF

    Elmwood Avenue Professional Office Space

    2555 Elmwood Ave, Buffalo, NY 14217

    3,000 SF office space in high-traffic Kenmore/Elmwood corridor.

    • High‑visibility location on Elmwood Avenue with strong daily traffic counts.
    • 3,000 SF of flexible office space suitable for various professional uses.
    • On‑site parking for staff and clients.
    • Central air conditioning and forced air natural gas heating.
    • Close proximity to retail, restaurants, and dense residential neighborhoods.
    Updated: Jan 13
    View details
    Spacious Commercial Building, Buffalo, NY
    $499,900
    5,012 SF

    Spacious Commercial Building, Buffalo, NY

    1609 Genesee St, Buffalo, NY 14211

    Versatile commercial building with parking, suitable for various businesses.

    • High‑visibility location on Genesee St with oversized parking lot (25+ spaces).
    • Over 5,000 sq. ft. of versatile commercial space suitable for various business types.
    • Fully accessible with elevator, wheelchair ramp, and wide hallways.
    • Valid Certificate of Occupancy and ready for immediate use.
    • Two‑story brick building with 4 bathrooms, laundry areas on each level, and kitchen area.
    Updated: Dec 3, 2025
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    Jefferson Utica Plaza: Medical & Office Space
    $8 SF/Yr
    28,290 SF

    Jefferson Utica Plaza: Medical & Office Space

    Prime Erie County medical/office suites available.

    1307 Jefferson Ave, Buffalo, NY 14208
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    West Seneca Medical Office Space
    Contact for pricing
    18,607 SF

    West Seneca Medical Office Space

    Prime Medical Office Suites Available in Buffalo, NY

    550 Orchard Park Rd, West Seneca, NY 14224
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    170 Franklin Street Office Space
    $13 SF/Yr
    76,088 SF

    170 Franklin Street Office Space

    Historic Downtown Buffalo Office Building

    172 Franklin St, Buffalo, NY 14202
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    Main Street Office Building
    $14 SF/Yr
    36,399 SF

    Main Street Office Building

    Prime Buffalo Office Space, 1,331-12,133 SF

    1010 Main Rd, Buffalo, NY 14202
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    Delaware Ave Office Space
    $16 SF/Yr
    38,450 SF

    Delaware Ave Office Space

    Prime Buffalo Office, 1,196 SF Available

    936 Delaware Ave, Buffalo, NY 14209
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    1115 Main St Office Space
    $21 SF/Yr
    32,211 SF

    1115 Main St Office Space

    Prime Buffalo Medical Campus Office

    1115 Main Rd, Buffalo, NY 14209
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    Prime Williamsville Office Building
    $10 SF/Yr
    11,512 SF

    Prime Williamsville Office Building

    11,512 SF Executive/Medical Office

    8705 Sheridan Dr, Buffalo, NY 14221
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    West Seneca Office Space Available
    $240 SF/Yr
    15,181 SF

    West Seneca Office Space Available

    15,181 SF Office Building, 5,940 SF Vacant

    1900 Ridge Rd, West Seneca, NY 14224
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    110 Broadway Office Space
    $22 SF/Yr
    51,552 SF

    110 Broadway Office Space

    Downtown Buffalo Office Building, Multiple Suites Available

    110 Broadway St, Buffalo, NY 14203
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    Prime Buffalo Office Space
    $17 SF/Yr
    38,682 SF

    Prime Buffalo Office Space

    10,000+ SF Available, Main Street Location

    1100 Main Rd, Buffalo, NY 14209
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    Kenmore Ave Office Suites
    $8 SF/Yr
    12,270 SF

    Kenmore Ave Office Suites

    Buffalo Office Space: Flexible Lease Options

    974-976 Kenmore Ave, Buffalo, NY 14216
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    Prime Buffalo Office Space
    $15 SF/Yr
    15,696 SF

    Prime Buffalo Office Space

    Class A Office Suites Available

    531 Farber Lakes Dr, Buffalo, NY 14221
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    Williamsville Medical Office Building
    $19 SF/Yr
    40,000 SF

    Williamsville Medical Office Building

    Class A Office Space, Flexible Lease Options

    1150 Youngs Rd, Buffalo, NY 14221
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    270 Michigan Ave Office Space
    $19 SF/Yr
    109,880 SF

    270 Michigan Ave Office Space

    Buffalo CBD Office, Retail, Industrial

    270 Michigan Ave, Buffalo, NY 14203
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    Elmwood Ave Office Space For Lease
    $12 SF/Yr
    4,800 SF

    Elmwood Ave Office Space For Lease

    Versatile Office Building, 4,500 SF Available

    2282 Elmwood Ave, Buffalo, NY 14217
    View details
    University Commons Office Park
    $18 SF/Yr
    79,112 SF

    University Commons Office Park

    Amherst Office Space: 1,395-2,666 SF Available

    1400-1416 Sweet Home Rd, Buffalo, NY 14228
    View details
    Buffalo Office Space: Chandler St.
    $9 SF/Yr
    5,921 SF

    Buffalo Office Space: Chandler St.

    Modern Office Suites in Buffalo, NY

    155 Chandler St, Buffalo, NY 14207
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    Ellicott Street Office Space Available
    $16 SF/Yr
    4,309 SF

    Ellicott Street Office Space Available

    Versatile Office Space, Prime Location

    969 Ellicott St, Buffalo, NY 14209
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    1088 Niagara St Office Space
    $22 SF/Yr
    11,000 SF

    1088 Niagara St Office Space

    West Buffalo Office/Retail Opportunity

    1088 Niagara St, Buffalo, NY 14213
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    Amherst Medical Office Suite
    Contact for pricing
    10,228 SF

    Amherst Medical Office Suite

    1,400 SF Medical Office, High Visibility

    1630 Maple Rd, Buffalo, NY 14221
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    1091 Main Street Office Space
    $31 SF/Yr
    194,500 SF

    1091 Main Street Office Space

    Modern Buffalo Office Building, Multiple Suites Available

    1091 Main Rd, Buffalo, NY 14209
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    Prime Buffalo Office Building
    $16 SF/Yr
    12,000 SF

    Prime Buffalo Office Building

    12,000 SF Office, Sale/Lease

    2060 Sheridan Dr, Buffalo, NY 14223
    View details

    Buffalo, NY Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Buffalo, NY with 80 listings featured on our commercial real estate exchange. The current inventory includes 58,249,041,840 square feet of properties with an estimated lease value of $802 /Mo.

    Estimated lease rates for Medical offices in Buffalo, NY begin at $8 SF/Yr, with an average of $22 SF/Yr and extend to $240 SF/Yr.
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    Browse Medical offices for Lease Near Buffalo, NY

    Popular Searches in Buffalo, NY

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    Most Searched ZIP Codes in Buffalo, NY

    • 14221
    • 14209
    • 14203
    • 14224
    • 14202
    • 14207
    • 14217
    • 14223
    • 14228
    • 14208
    • 14210
    • 14211

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