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    West Seneca, NY Commercial Real Estate for Sale

    34 results
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    West Seneca Office Building For Sale
    Pending
    $560,000
    6,480 SF

    West Seneca Office Building For Sale

    20 N America Dr, West Seneca, NY 14224

    6,480 SF office building in prime West Seneca location.

    • Prime West Seneca location with excellent accessibility, minutes from the 400 Expressway and Union Road.
    • Spacious 6,480 sq ft office building suitable for various business types and sizes.
    • Ample on‑site parking for employees and visitors.
    • Convenient proximity to major highways, public transportation, restaurants, shops, and services.
    • Modern, professional brick exterior.
    Updated: Oct 23, 2025
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    Modern Commercial Property in Orchard Park
    Pending
    $3,000,000
    9,865 SF

    Modern Commercial Property in Orchard Park

    3020 Orchard Park Rd, West Seneca, NY 14224

    Two-story commercial property with drive-thru, built in 2017.

    • Modern commercial property built in 2017.
    • Large building size: 9,865+ sq ft on a 1.5‑acre lot.
    • Includes a three‑bay drive‑thru teller station.
    • Equipped with an elevator providing access to all floors.
    • Features a natural gas back‑up generator and comprehensive security system (fire alarm, video surveillance, sprinkler system).
    Updated: Dec 30, 2025
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    I-90 Regional Development Site
    Contact for pricing
    93,100 SF

    I-90 Regional Development Site

    Prime West Seneca medical office & development land

    355 Orchard Park Rd, West Seneca, NY 14224
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    Clinton Street Funeral Home
    $749,000
    7,573 SF

    Clinton Street Funeral Home

    West Seneca, NY Funeral Home - $749,000

    3640 Clinton St, West Seneca, NY 14224
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    West Seneca Auto Center & Land
    $999,999
    4,702 SF

    West Seneca Auto Center & Land

    Prime Auto Center, Residential Lots

    2671 Seneca St, West Seneca, NY 14224
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    Remodeled Two-Family Home
    $164,900

    Remodeled Two-Family Home

    Two-unit home with remodeled first floor and updated second floor.

    2115 Union Rd, West Seneca, NY 14224
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    West Seneca Multifamily Investment
    $270,000

    West Seneca Multifamily Investment

    Well-maintained duplex with updated features, ideal for investors.

    125 Brookside Dr, West Seneca, NY 14220
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    West Seneca Former Medical Office
    Contact for pricing

    West Seneca Former Medical Office

    36,346 SF medical office space for sale/lease.

    130 Empire Dr, West Seneca, NY 14224
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    Restaurant Investment Property on Transit
    $950,000

    Restaurant Investment Property on Transit

    Fully leased restaurant property on Transit Road with ample parking.

    3100 Transit Rd, West Seneca, NY 14224
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    Union Road Medical Investment Property
    $1,199,900
    6,000 SF

    Union Road Medical Investment Property

    Cash flowing medical property with long-term tenant on Union Road.

    2100 Union Rd, West Seneca, NY 14224
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    Mixed-Use Property with Apartment
    Contact for pricing

    Mixed-Use Property with Apartment

    Former bar/restaurant with apartment for lease in West Seneca.

    3036 Seneca St, West Seneca, NY 14224
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    Established Motel on Southwestern Blvd
    $950,000

    Established Motel on Southwestern Blvd

    Fully functioning 13-room motel with development potential.

    1650 Southwestern Blvd, West Seneca, NY 14224
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    Freestanding Office Building Opportunity
    $134,900

    Freestanding Office Building Opportunity

    Office building with potential for customization and multiple uses.

    1403 Union Rd, West Seneca, NY 14224
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    Versatile Commercial Building with Development Potential
    $1,500,000
    15,000 SF

    Versatile Commercial Building with Development Potential

    15,000+ sq ft commercial building with development opportunity.

    1475 Orchard Park Rd, West Seneca, NY 14224
    View details
    Freestanding Building Near Southgate Plaza
    $325,000
    2,135 SF

    Freestanding Building Near Southgate Plaza

    2,135 SF building on 0.62 acres near Route 400.

    4080 Seneca St, West Seneca, NY 14224
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    Turn-Key Restaurant Opportunity
    Contact for pricing

    Turn-Key Restaurant Opportunity

    Fully equipped restaurant/bar with expansion potential in West Seneca, NY.

    1492 Southwestern Blvd, West Seneca, NY 14224
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    Multifamily Property in West Seneca
    $249,900

    Multifamily Property in West Seneca

    Multifamily property for sale in West Seneca, NY.

    25 Fernwood Ave, West Seneca, NY 14206
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    West Seneca Auto Body Shop
    $299,999
    1,740 SF

    West Seneca Auto Body Shop

    Three-bay auto shop or retail opportunity near Aurora Expressway.

    2976 Seneca St, West Seneca, NY 14224
    View details
    West Seneca Warehouse Opportunity
    $170,000
    2,960 SF

    West Seneca Warehouse Opportunity

    Freestanding warehouse building, ideal for distribution or storage.

    644-646 Potters Rd, West Seneca, NY 14224
    View details
    Kaisertown Auto Repair Shop Investment
    $324,900
    4,694 SF

    Kaisertown Auto Repair Shop Investment

    Auto repair shop with lease in place for steady income.

    2085 Clinton St, West Seneca, NY 14206
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    Retail Property with Corporate Guaranty
    $2,394,370
    15,059 SF

    Retail Property with Corporate Guaranty

    Retail property with a corporate-guaranteed lease and expansion options.

    25 Gardenville Pkwy, West Seneca, NY 14224
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    West Seneca Four Bedroom Double
    $309,900

    West Seneca Four Bedroom Double

    Meticulously maintained duplex in West Seneca school district.

    194 Boncroft Dr, West Seneca, NY 14224
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    Prime Commercial Property Near Seneca
    $749,000

    Prime Commercial Property Near Seneca

    4,282 sq ft commercial property with high visibility.

    3001 Ridge Rd, West Seneca, NY 14224
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    Artistic 1930s West Seneca Duplex
    $279,900

    Artistic 1930s West Seneca Duplex

    Well-maintained 1930s duplex with original features and modern updates.

    146 Chamberlin Dr, West Seneca, NY 14210
    View details

    West Seneca, NY Commercial Real Estate Investment Opportunities Market Analysis

    Explore 165 commercial real estate investment opportunities in West Seneca, NY with 34 listings featured on our commercial real estate marketplace. The current inventory includes 8,643,757 square feet of properties with an estimated value of $53,843,899.

    Estimated prices for commercial real estate in West Seneca, NY begin at $100,000, with an average of $555,091 and extend to $4,680,000.

    In West Seneca, NY, current investment values show:

    • Investment properties positioned at $290,517
    • Mixed-use properties measuring $290,517
    • Other investment properties assessed at $290,517
    • Retail properties calculated at $758,958
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    Browse Commercial real estate for Sale Near West Seneca, NY

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    Most Searched ZIP Codes in West Seneca, NY

    • 14224
    • 14210
    • 14206
    • 14220
    • 14218
    • 14127

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