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    South Carolina Medical Office Space for Lease

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    183 properties
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    Medical Office Condo End Cap
    Medical Office Condo End Cap

    5401 Netherby Lane Ste 601, North Charleston, SC 29420

    Contact for pricing

    End cap medical office condo with private offices, conference space, and parking within a professional park.

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    Single-Story Retail Office Medical Building
    Single-Story Retail Office Medical Building

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,730 sqft

    Pre-leasing is underway for a single-story retail, office, and medical building with a planned Fall 2026 delivery.

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    Single-Story Medical Office Retail
    Single-Story Medical Office Retail

    128 Bluffton Rd, Bluffton, SC 29910

    Contact for pricing
    2,655 sqft

    Pre-leasing single-story retail and office building planned for delivery in Fall 2026.

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    Cayce Office/Medical Space Available
    Cayce Office/Medical Space Available

    1105 State St, Cayce, SC

    Contact for pricing
    5,670 sqft 0.48 AC lot

    5,670 SF building suitable for office or medical use.

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    Class A Medical Office Suite
    Class A Medical Office Suite

    1650 Skylyn Dr, Spartanburg, SC 29307

    Contact for pricing
    2,132 sqft

    NNN-leased Class A medical office suite with ample parking and an on-site gym.

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    Fully Plumbed Medical Office Suites
    Fully Plumbed Medical Office Suites

    1701 Saint Julian Pl, Columbia, SC 29204

    Contact for pricing
    14,442 sqft

    Medical office space fully plumbed for medical use, offering multiple suite options with 60 parking spots.

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    Move-in Ready Office Space
    Move-in Ready Office Space

    144 Leisure Ln, Columbia, SC

    Contact for pricing
    4,000 sqft 0.68 AC lot

    4,000 SF office space for lease in Columbia, SC.

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    Medical Office Building with Monument Signage
    Medical Office Building with Monument Signage

    101 Medical Cir, West Columbia, SC 29169

    Contact for pricing
    6,300 sqft

    Flexible commercial office space supports medical or traditional office use.

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    Medical Office Space
    Medical Office Space

    8910 Two Notch Road, Columbia, SC 29223

    Contact for pricing

    Professional office space available near major interstates and retail centers in northeast Columbia.

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    Medical Office Space with On-Site Parking
    Medical Office Space with On-Site Parking

    4100 N Main St, Columbia, SC 29203

    Contact for pricing
    1,226 sqft

    Primarily configured for clinical and medical uses, with the flexibility to support traditional office needs and on-site parking.

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    End-Cap Office Suite
    End-Cap Office Suite

    2431 Aviation Avenue # 709, North Charleston, SC 29406

    Contact for pricing
    6,127 sqft

    Professional workspace combines enclosed offices with open-plan area and abundant natural light.

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    Second-Generation Medical Office Building
    Second-Generation Medical Office Building

    100 Jimmy Love Ln, Columbia, SC 29212

    Contact for pricing

    Medical office building with existing exam and clinical areas, delivering vacant and ready for medical-related occupancy.

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    Medical Office Space For Lease
    Medical Office Space For Lease

    1000 Wellness Way, Fort Mill, SC 29715

    Contact for pricing

    Medical office space available for lease at 1000 Wellness Way in Fort Mill, SC.

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    Medical Office Building For Sale
    Medical Office Building For Sale

    1701 Saint Julian Pl, Columbia, SC

    Contact for pricing
    14,442 sqft 0.87 AC lot

    Medical office building with ample parking near medical campuses.

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    Office Unit with X-Ray Room
    Office Unit with X-Ray Room

    3841 Rivers Avenue, North Charleston, SC 29405

    Contact for pricing
    3,361 sqft

    Configured for professional operations with reception, conference rooms, kitchen, and an executive suite.

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    Medical Office Suite with Exam Rooms
    Medical Office Suite with Exam Rooms

    2891 Tricom Street Ste B, North Charleston, SC 29406

    Contact for pricing

    Suite includes reception, two exam rooms/offices, an open work area, and two bathrooms on an NNN basis.

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    Medical Office Corner Suite
    Medical Office Corner Suite

    2901-2903 Millwood Ave, Columbia, SC 29205

    Contact for pricing
    4,200 sqft

    Corner office suite with reception, open workspace, conference rooms, private offices, and seven off-street parking spaces.

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    Built-Out Medical Office Suite
    Built-Out Medical Office Suite

    205 Central Park Ln, Seneca, SC 29678

    $17.50 SF/Yr

    Fully built-out suite with clinical rooms, reception, conference space, and staff amenities.

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    Medical Office Space with 11 Treatment Rooms
    Medical Office Space with 11 Treatment Rooms

    1334 Ebenezer Rd, Rock Hill, SC 29732

    Contact for pricing
    4,135 sqft

    Free-standing medical office with 11 treatment rooms, training room, and parking for 24 plus two handicap spaces.

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    Medical Office Space with Ample Parking
    Medical Office Space with Ample Parking

    1033 Bayshore Dr, Rock Hill, SC 29732

    Contact for pricing
    3,675 sqft

    Well-maintained medical office space with ample parking, about five minutes from I-77 off Celanese Rd.

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    Free-Standing Medical Office Suite
    Free-Standing Medical Office Suite

    9133 Timber Street Suite A, North Charleston, SC 29406

    Contact for pricing

    Free-standing medical office suite with reception, offices, bathrooms, and a breakroom for lease on an NNN basis.

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    West Ashley Medical Office Sublease
    West Ashley Medical Office Sublease

    2270 Ashley Crossing Ln, Charleston, SC

    Contact for pricing
    3,746 sqft 8.99 AC lot

    3,746 SF medical office space available for immediate sublease.

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    Lower-Level Office Suite with Lab Room
    Lower-Level Office Suite with Lab Room

    1405 Grove Road, Greenville, SC 29605

    Contact for pricing

    Lower-level suite with private offices, conference room, and lab/work room for medical or professional operations.

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    Medical Office Space Available
    Medical Office Space Available

    300 Regent Park Ct, Greenville, SC 29607

    Contact for pricing

    Office spaces for healthcare providers near I-385 & Butler Rd.

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