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    South Carolina Medical Offices for Lease

    179 results
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    Lady's Island Versatile Office Space
    $3,600 / Mo
    19,602 SF

    Lady's Island Versatile Office Space

    27 Kemmerlin Ln, Beaufort, SC 29907

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    • Versatile 1,500 SF office space suitable for medical, wellness, salon, or traditional office use.
    • 7 treatment rooms with plumbing stubbed and capped.
    • Located in Kemmerlin Business Park with noteworthy businesses and organizations.
    • Newly renovated lobby, two ADA restrooms, and kitchenette.
    • Front and rear covered patios and ~15 shared parking spaces.
    Updated: Feb 24
    View details
    Murrells Inlet Office Space
    $2,400 / Mo
    1,250 SF

    Murrells Inlet Office Space

    637 Bellamy Ave, Murrells Inlet, SC 29576

    Multi-tenant office/retail/medical building with easy highway access. Available 4/1/26.

    • Easy access to Highway 17 Bypass, Murrells Inlet Rd, Highway 707, and Highway 17 Business.
    • 1,250 SF First Floor Office Space.
    • Suitable for Office/Retail/Medical Use.
    • Includes Three (3) Offices, Conference Room, Reception/Waiting Area.
    • Features a Break Room and One (1) Restroom.
    Updated: Feb 4
    View details
    Office Space Near Clemson
    $4,000 / Mo
    26,136 SF

    Office Space Near Clemson

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
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    Seneca Office Space For Lease
    $1,500 / Mo
    26,136 SF

    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
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    Aiken Office/Medical Space Available
    $4,810 / Mo
    2,540 SF

    Aiken Office/Medical Space Available

    Office and medical suites available for sublease in Aiken, SC.

    5000 Woodside Executive Ct, Aiken, SC 29803
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    Aiken Office Space for Rent
    $4,810 / Mo
    2,540 SF

    Aiken Office Space for Rent

    Renovated office space suitable for medical or administrative uses.

    5000 Woodside Executive Ct, Aiken, SC 29803
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    Medical Office in Woodside Village
    $6,378 / Mo
    2,639 SF

    Medical Office in Woodside Village

    Stand-alone medical office in a live, work, play community.

    210 High Gate Loop, Aiken, SC 29803
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    Rock Hill Medical Office Space
    $2,600 / Mo
    46,313 SF

    Rock Hill Medical Office Space

    Move-in ready medical office space near Piedmont Medical Center.

    744 Arden Ln, Rock Hill, SC 29732
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    Aiken Office Space For Lease
    $3,772 / Mo
    1,886 SF

    Aiken Office Space For Lease

    New build-out opportunity for office or medical space in Aiken.

    148 SW Unit, Aiken, SC 29801
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    Pawleys Island Professional Office Space
    $3,632 / Mo
    1,981 SF

    Pawleys Island Professional Office Space

    Versatile office space in high-visibility Pawleys Island location.

    38 Blackgum Rd, Pawleys Island, SC 29585
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    Class A Office Space
    $3,400 / Mo

    Class A Office Space

    Professional office suite for rent in Anderson, SC.

    2315 N Main St, Anderson, SC 29621
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    Ridgeland Medical Office Space
    $18 SF/Yr
    110,207 SF

    Ridgeland Medical Office Space

    Turnkey medical office space available for lease in Ridgeland.

    11382 N Jacob Smart Blvd, Ridgeland, SC 29936
    View details
    Myrtle Beach Office Space For Rent
    $3,000 / Mo
    2,340 SF

    Myrtle Beach Office Space For Rent

    2340 sq ft commercial space perfect for medical or professional office.

    8210 Devon Ct, Myrtle Beach, SC 29572
    View details
    Medical/Professional Office Near Conway Hospital
    $6,251 / Mo
    5,246 SF

    Medical/Professional Office Near Conway Hospital

    Medical/professional office building near Conway Medical Center with customizable space.

    8028 Myrtle Trace Dr, Conway, SC 29526
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    New Office Complex For Lease
    $1,800 / Mo
    1,150 SF

    New Office Complex For Lease

    Office complex in Carolina Forest retail/professional/office area.

    4225 Carolina Exchange Dr, Myrtle Beach, SC 29579
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    Medical Office Suite For Lease
    $2,214 / Mo
    1,155 SF

    Medical Office Suite For Lease

    Turn-key medical office suite in Georgetown, available May 1, 2025.

    1001 N Fraser St, Georgetown, SC 29440
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    Retail, Restaurant, or Medical Office
    Contact for pricing
    24,000 SF

    Retail, Restaurant, or Medical Office

    Located in a Publix-anchored shopping center with high visibility.

    2800 Rosewood Dr, Columbia, SC 29205
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    Medical Office Space For Lease
    $20 SF/Yr
    7,659 SF

    Medical Office Space For Lease

    Medical office space in prime healthcare corridor location.

    161 Medical Cir, West Columbia, SC 29169
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    Medical Office Space Available
    $30 SF/Yr
    1,500 SF

    Medical Office Space Available

    1,500 SF medical office for lease in Murrells Inlet.

    830 Inlet Square Dr, Murrells Inlet, SC 29576
    View details
    Move-in Ready Office Space
    $15 SF/Yr
    4,000 SF

    Move-in Ready Office Space

    4,000 SF office space for lease in Columbia, SC.

    144 Leisure Ln, Columbia, SC 29210
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    Greenville Medical Office Space
    $30 SF/Yr
    2,600 SF

    Greenville Medical Office Space

    Modern medical office space available for lease in Greenville, SC.

    3807 White Horse Rd, Greenville, SC 29611
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    Lake City Retail/Office Building
    $10 SF/Yr
    11,000 SF

    Lake City Retail/Office Building

    Retail/office building in Lake City available through 1/31/2032.

    231 Kelley St, Lake City, SC 29560
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    West Ashley Medical Office Space
    $22 SF/Yr
    3,000 SF

    West Ashley Medical Office Space

    3,000 SF office space in the heart of West Ashley.

    1027 Physicians Dr, Charleston, SC 29414
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    Turn Key Medical Office Space
    $29 SF/Yr
    2,587 SF

    Turn Key Medical Office Space

    Move-in ready medical office space near East Cooper Hospital.

    897 Von Kolnitz Rd, Mount Pleasant, SC 29464
    View details

    South Carolina Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in South Carolina with 320 listings featured on our commercial real estate exchange. The current inventory includes 108,287,537,212 square feet of properties with an estimated lease value of $2,434 /Mo.

    Estimated lease rates for Medical offices in South Carolina begin at $0.67 SF/Yr, with an average of $22 SF/Yr and extend to $90 SF/Yr.
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