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    South Carolina Commercial Real Estate for Lease

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    3,255 properties
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    Newly Renovated Office Building
    Newly Renovated Office Building

    3265 N Carolina Ave, North Charleston, SC 29405

    $2,123/Mo
    2,400 sqft

    Newly renovated office building with ample on-site parking and convenient access to major roads.

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    Office Suite with Private Offices
    Office Suite with Private Offices

    4259 Whiskey Road, Aiken, SC 29803

    $2,600/Mo
    1,500 sqft

    Well-appointed office layout with three private offices, reception, conference room, kitchen, and restroom, available June 1, 2026.

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    Newly Renovated Office Building
    Newly Renovated Office Building

    1034 Briargate Circle, Columbia, SC 29210

    $1,300/Mo
    2,328 sqft

    Two-story suites offer multiple offices, a conference room, storage, and reception space with on-site parking.

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    Downtown Restaurant Space
    Downtown Restaurant Space

    220 Georgia Ave, North Augusta, SC 29841

    $2,800/Mo
    1,440 sqft

    Restaurant space with an existing commercial hood, dining area, storage, and a single restroom.

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    Downtown Professional Office Suite
    Downtown Professional Office Suite

    1003 Prince St., Georgetown, SC 29440

    $2,180/Mo
    1,189 sqft

    Office suite with a reception area and two private offices, located one block from Front St.

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    Industrial Warehouse with Dock and Drive-In
    Industrial Warehouse with Dock and Drive-In

    7224 Middle Street, Columbia, SC 29223

    $5,500/Mo
    8,000 sqft

    Functional warehouse with 14-foot ceilings, dock high and drive-in doors, and office space for distribution or light manufacturing.

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    First-Floor Medical Office Suite
    First-Floor Medical Office Suite

    100-a-2315 N Main Street, Anderson, SC 29621

    $500/Mo
    100 sqft

    First-floor private office suite in a two-story, all-brick Class A building with shared kitchenette and conference room.

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    Professional Office Space Available
    Professional Office Space Available

    5187 Horry Dr., Murrells Inlet, SC 29576

    $3,670/Mo
    1,000 sqft

    Professional office space for lease in Murrells Inlet, SC.

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    Two-Story Office-Retail Building
    Two-Story Office-Retail Building

    276 East Bay Street, Charleston, SC 29401

    $42 SF/Yr
    14,518 sqft

    Two-story office/retail lease space at Historic Downtown Charleston with potential subdivision and on-site parking.

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    Industrial Warehouse with Loading Dock
    Industrial Warehouse with Loading Dock

    2969 Wagener Rd Unit A1, Aiken, SC 29801

    $8,000/Mo
    15,080 sqft

    Industrial suite offers loading dock access, fenced yard, and 240V 3-phase power with dedicated office and restrooms.

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    Office Suite with High-End Finishes
    Office Suite with High-End Finishes

    1801 North Main Street, Anderson, SC 29621

    $18 SF/Yr
    1,800 sqft

    Well-finished office suite with private offices, conference space, ample parking, and strong visibility for professional teams.

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    Free-Standing Brick Office Building
    Free-Standing Brick Office Building

    1598 Columbia Highway, Aiken, SC 29801

    $1,950/Mo
    1,494 sqft

    Zoned UD free-standing brick office with tile floors and parking lot; public water and septic tank service.

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    Restored Office Space in Historic Building
    Restored Office Space in Historic Building

    4 / 8 North Atlantic Wharf, Charleston, SC 29401

    $30 SF/Yr
    2,566 sqft

    Restored office unit with open workspace, private offices, and conference room in a historic Charleston building.

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    Office Warehouse in Murrells Inlet
    Office Warehouse in Murrells Inlet

    11772 S Highway 17 Bypass, Murrells Inlet, SC 29576

    $3,000/Mo
    2,200 sqft

    Office warehouse building for lease with great location and visibility.

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    Warehouse/Flex Units with 16' Doors
    Warehouse/Flex Units with 16' Doors

    1970 Highway 905, Conway, SC 29526

    $14 SF/Yr
    3,250 sqft

    Flex-warehouse suites with 16' drive-in bays and RE-4 zoning for office, retail, and service uses.

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    Mixed-Use Property in Cayce, SC
    Mixed-Use Property in Cayce, SC

    528-532 Knox Abbott Dr, Cayce, SC 29033

    $825/Mo
    7,541 sqft

    Mixed-use property suitable for redevelopment, retail, or office use.

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    6,000 SF Secured Warehouse Facility
    6,000 SF Secured Warehouse Facility

    7710 Southrail Rd, North Charleston, SC 29420

    $5,514/Mo
    5,514 sqft

    Metal warehouse includes 500 SF of office space, three drive-in doors, and a 5,514 SF clear-span warehouse.

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    Medical Office Suites with Ample Parking
    Medical Office Suites with Ample Parking

    1300 Hospital Dr, Mt Pleasant, SC 29464

    $1,757/Mo
    3,425 sqft

    Three-story medical office building offers suites for lease with ample on-site paved parking.

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    Office Suite with Three Rooms
    Office Suite with Three Rooms

    209 Silver Bluff Rd, Aiken, SC 29803

    $1,250/Mo
    1,450 sqft

    Three-room office suite with kitchen and reception area, plus ample rear parking for a convenient tenant experience.

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    Quaint Restaurant Space with Parking
    Quaint Restaurant Space with Parking

    2304 N Kings Hwy, Myrtle Beach, SC 29577

    $2,500/Mo
    969 sqft

    Small restaurant space with a comfortable dining area, ample storage, and convenient parking for dine-in and take-away service.

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    Renovated End-Unit Office Suite
    Renovated End-Unit Office Suite

    452 Browns Cove Rd, Ridgeland, SC 29936

    $2,800/Mo
    1,250 sqft

    Newly renovated end-unit office suite with a reception foyer, multiple private offices, and an updated bathroom.

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    Corner Office Suite
    Corner Office Suite

    501 S Wise Drive, Sumter, SC 29150

    $1,660/Mo
    1,459 sqft

    Corner office space with CAM including parking lot and landscape maintenance, area lights, and related insurance and tax overages.

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    Industrial Warehouse with Loading
    Industrial Warehouse with Loading

    1020 Industrial Court, Lexington, SC 29072

    $10 SF/Yr
    12,000 sqft

    Warehouse with 1 drive-in and 4 loading doors, plus 16'–17' ceiling height and up to 5% office included.

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    Office Suite with Private Offices
    Office Suite with Private Offices

    228 Silver Bluff Rd, Aiken, SC 29803

    $2,000/Mo
    1,246 sqft

    Well-appointed office suite with multiple private rooms, hardwood finishes, and on-site parking arrangements.

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