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    South Carolina Commercial Real Estate for Lease

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    3,004 properties
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    Open Retail Suite
    Open Retail Suite

    575 Broad Street, Sumter, SC 29150

    $1,500/Mo
    1,100 sqft

    The space faces O'Reilly's Auto Parts across Broad Street in Sumter.

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    Office Unit with Balcony
    Office Unit with Balcony

    4603 Oleander Dr., Myrtle Beach, SC 29577

    $1,750/Mo
    3–5 people  800 sqft  0.16 acres  Framed Wood
    4 private offices

    The suite combines private offices with reception, kitchen, restroom, and paved on-site parking.

    45 parking spaces  Balcony  Landscaping
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    Renovated Stand-Alone Office Building
    Renovated Stand-Alone Office Building

    725 East Martintown Road, North Augusta, SC 29841

    $16 SF/Yr
    11–18 people  1 space  2,822 sqft  Renovated 2020
    10 private offices  1 meeting rooms  Road access

    Flexible office layout with private rooms, meeting space, a breakroom, and dual-road access.

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    Freestanding Office Building
    Freestanding Office Building

    9250 Highway 17 Bypass #Building B, Murrells Inlet, SC 29576

    $8,432/Mo
    14–24 people  3,667 sqft  Renovated 2019  1-story
    1 meeting rooms

    The single-story floor plan has private offices and a glass-walled conference room, with central heat and air.

    Central heat and air  Public water and sewer  On-site parking
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    Main Street Frontage Retail Space
    Main Street Frontage Retail Space

    673 Main St., North Myrtle Beach, SC 29582

    $3,866/Mo
    1,450 sqft

    Modern center space with prominent signage opportunities, on-site parking, and GC zoning.

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    Restaurant Space Near I-95
    Restaurant Space Near I-95

    3751 W Palmetto St, Florence, SC 29501

    Triple net (NNN)
    $7,000/Mo
    4,190 sqft

    Two driveway connections and on-site parking support customer access.

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    New Retail Strip Center
    New Retail Strip Center

    4998 Carolina Forest Blvd. Unit 4, Myrtle Beach, SC 29579

    $9,447/Mo
    3,149 sqft  Built 2026

    New construction offers multiple suite configurations near established grocery, banking, and retail operators.

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    Flex Space with Covered Loading
    Flex Space with Covered Loading

    130 Wing Hill Drive SUITE B, Lexington, SC 29072

    $4,900/Mo
    4,200 sqft  16.8 ft clear  3-phase  Built 1986

    An adaptable interior pairs warehouse and shop areas with private offices, restrooms, and support space.

    Utilities to site
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    Flex Space with Loading Docks
    Flex Space with Loading Docks

    2220 Highway 643, Myrtle Beach, SC 29577

    $4,119/Mo
    3,600 sqft  2 docks
    Highway access

    LI-zoned commercial unit with roll-up access and dock loading near major Myrtle Beach routes.

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    Light Industrial Flex Suites
    Light Industrial Flex Suites

    12 Cardinal Rd, Hilton Head Island, SC 29926

    $2,100/Mo
    5,090 sqft  2 drive-in  Heavy power

    Two leaseable flex units include warehouse and office space with roll-up and drive-in doors plus dock access and a shared yard.

    Outdoor storage  Fenced yard
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    Medical-Retail Mixed-Use Space
    Medical-Retail Mixed-Use Space

    5100 Highway 17 Bypass, Murrells Inlet, SC 29576

    $3,125/Mo
    Multi-tenant  2,500 sqft  12,000 sqft building
    Highway access  Road access

    The available area can be configured as two suites or leased as a single space.

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    Renovated Medical Office Suite
    Renovated Medical Office Suite

    5000 Woodside Executive Ct, Aiken, SC 29803

    $4,278/Mo
    2,540 sqft  Built 1989  8 acres

    Newly renovated second-floor suite with kitchenette, conference room, six rooms, and private reception and bathroom.

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    Flex Space with Storefront
    Flex Space with Storefront

    1540 Highway 501, Myrtle Beach, SC 29577

    $2,150/Mo
    13,000 sqft

    An open ground-floor layout is complemented by an upper level suited to storage, inventory, or office functions.

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    Two-Story Office Units
    Two-Story Office Units

    1089 Augusta Road, Warrenville, SC 29851

    Modified gross
    $7,000/Mo
    36–60 people  9,000 sqft  Built 1975

    Adaptable commercial space with CAT6 infrastructure, controlled entry, surveillance cameras, and public water and sewer service.

    70 parking spaces
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    Two-Story Office Units
    Two-Story Office Units

    1089 Augusta Road, Warrenville, SC 29851

    Modified gross
    $7,000/Mo
    36–60 people  9,000 sqft  Built 1975  2.48 acres

    Available office space offers adaptable layouts, on-site parking, public utilities, and dedicated CAT6 infrastructure.

    50 parking spaces
    View details
    Flex Space with Laydown Yard
    Flex Space with Laydown Yard

    854 Kingswood Dr., Conway, SC 29526

    $6,397/Mo
    4,828 sqft
    Highway access  Road access

    Office and warehouse space is paired with an outdoor yard for equipment or materials staging.

    Outdoor storage
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    Flex Building with Dock High Doors
    Flex Building with Dock High Doors

    141 Dutchman Boulevard, Irmo, SC 29063

    $12.50 SF/Yr
    7,500 sqft  16 ft clear  2 docks  2,000 sqft office
    LI

    Flex building in LI zoning with two dock high doors, fenced loading area, and 10 on-site parking spaces.

    Outdoor storage  Fenced yard  10 parking spaces
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    Six-Office Professional Suite
    Six-Office Professional Suite

    130 Wing Hill Drive Suite A, Lexington, SC 29072

    $2,100/Mo
    7–12 people  1,800 sqft  Built 1986

    A flexible office configuration includes a reception area, kitchen-equipped break room, and two restrooms.

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    Flex Space with Showroom
    Flex Space with Showroom

    879 By Pass 123 Highway Includes 710 Seneca Dr, Seneca, SC 29678

    Triple net (NNN)
    $2,000/Mo
    3,264 sqft  Built 1980

    Two commercial buildings combine customer-facing space with office, service, and garage functionality under an NNN lease structure.

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    Drugstore Property with Drive-Through
    Drugstore Property with Drive-Through

    512 S Kings Hwy., Myrtle Beach, SC 29577

    $15,075/Mo
    10,050 sqft

    HC-2-zoned property at a signalized intersection with monument signage and multiple curb cuts.

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    Nine-Room Office Building
    Nine-Room Office Building

    118 Park Avenue SE, Aiken, SC 29801

    $2,800-$3,200/Mo
    10–16 people  2,522 sqft  Built 1975

    The floor plan includes two bathrooms and is suited to office or professional-service use.

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    Three Office Suites with Atrium
    Three Office Suites with Atrium

    7301 Rivers Ave, North Charleston, SC 29406

    $1,210/Mo
    10–17 people  2,591 sqft  2-story  brick
    Highway access + Road access

    Two-story brick property offers interstate access, an atrium lobby, and proximity to restaurants, shopping, and banks.

    Open atrium lobby  Live plants  Fountain  Marble flooring
    View details
    Retail Space Along Highway 90
    Retail Space Along Highway 90

    3080 Highway 90, Conway, SC 29526

    $4,800/Mo
    1,920 sqft

    A 1,920-square-foot space within a center serving Conway and Carolina Forest residents.

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    Office Building Near City Center
    Office Building Near City Center

    129 S Coit Street, Florence, SC 29501

    $1,400/Mo
    5–8 people  1,320 sqft  Built 1959

    A 1,320-square-foot office property built in 1959, positioned adjacent to City Center.

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